Guanidine hydrochloride and urea-induced unfolding of Brugia malayi hexokinase

European Biophysics Journal

Volumn 39, Issue 2, 2010, Pages 289-297

  Singh, Alok Ranjan ^a   Joshi, Shweta ^a   Arya, Rahul ^b   Kayastha, Arvind Mohan ^c   Saxena, Jitendra Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^c BANARAS HINDU UNIVERSITY   (India)

Author keywords

BmHk; Dimer; Guanidine hydrochloride; Multimeric protein; Urea denaturation

Indexed keywords

ANIMALS; BRUGIA MALAYI; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; GLUTARAL; GUANIDINE; HELMINTH PROTEINS; HEXOKINASE; KINETICS; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; SPECTROMETRY, FLUORESCENCE; UREA;

BRUGIA MALAYI;

EID: 73649098471     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-009-0539-5     Document Type: Article

References (36)

1. AE Aleshin C Zheng GP Bourenkov HD Bartunik HJ Fromm RB Honzatko 1998 The mechanism of regulation of hexokinase: new insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate Structure 6 39 50 10.1016/S0969-2126(98)00006-9 1:CAS:528:DyaK1cXhtVGltLw%3D 9493266
2. AE Aleshin HJ Fromm RB Honzatko 1998 Multiple crystal forms of hexokinase I: new insights regarding conformational dynamics, subunit interactions, and membrane association FEBS Lett 434 42 46 10.1016/S0014-5793(98)00952-1 1:CAS:528:DyaK1cXlsl2msr8%3D 9738448 (Pubitemid 28404659)
3. AE Aleshin C Zheng HD Bartunik HJ Fromm RB Honzantko 1998 Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate J Mol Biol 282 345 357 10.1006/jmbi.1998. 2017 1:CAS:528:DyaK1cXmtlClsb4%3D 9735292 (Pubitemid 28418788)
4. AE Aleshin C Kirby X Liu GP Bourenkov HD Bartunik HJ Fromm RB Honzatko 2000 Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation J Mol Biol 296 1001 1015 10.1006/jmbi.1999.3494 1:CAS:528:DC%2BD3cXht1Onu7k%3D 10686099 (Pubitemid 30695577)
5. CM Anderson RE Stenkamp RC McDonald TA Steiz 1978 Sequencing a protein by X-ray crystallography II. Refinement of yeast hexokinase B co-ordinates and sequence at 2.1 Å resolution J Mol Biol 123 15 34 10.1016/0022-2836(78) 90374-1 1:CAS:528:DyaE1cXlslGltbs%3D 355643
6. RL Armstrong JE Wilson CB Shoemaker 1996 Purification and characterization of the hexokinase from Schistosoma mansoni, expressed in Escherichia coli Protein Expr Purif 8 374 380 10.1006/prep.1996.0113 1:CAS:528:DyaK28XntFOluro%3D 8936600 (Pubitemid 27012298)
7. WS Bennet TA Steiz 1980 Structure of a complex between yeast hexokinase A and glucose I. Structure determination and refinement at 3.5 Å resolution J Mol Biol 140 183 209 10.1016/0022-2836(80)90102-3 (Pubitemid 11234485)
8. ML Cardenas A Cornish-Bowden T Ureta 1998 Evolution and regulatory role of hexokinases Biochim Biophys Acta 1401 242 264 10.1016/S0167-4889(97)00150-X 1:CAS:528:DyaK1cXhvFGmsL0%3D 9540816 (Pubitemid 28122343)
9. RS Gokhale SS Ray H Balram P Balram 1999 Unfolding of P. falciparum triose phosphate isomerase in urea and guanidinium hydrochloride: evidence for novel disulphide exchange reaction in a covalently cross-linked mutant Biochemistry 38 423 431 10.1021/bi981087s 1:CAS:528:DyaK1cXnvVKls7g%3D 9890925 (Pubitemid 29035713)
10. S Hayashi S Nakamura 1981 Multiple forms of glucose oxidase with different carbohydrate compositions Biochim Biophys Acta 657 40 51 1:CAS:528:DyaL3MXnvFSqtg%3D%3D 7213749
11. R Janicke 1987 Stability and folding of domain proteins Prog Biophys Mol Biol 49 117 237 10.1016/0079-6107(87)90011-3
12. R Janicke H Lillie 2000 Folding and association of oligomeric and multimeric proteins Adv Protein Chem 53 329 401 10.1016/S0065-3233(00)53007-1 (Pubitemid 34194297)
13. S Joshi AR Singh A Kumar I Siddiqui PC Misra JK Saxena 2008 Molecular cloning and characterization of Plasmodium falciparum transketolase Mol Biochem Parasitol 160 32 41 10.1016/j.molbiopara.2008.03.005 1:CAS:528: DC%2BD1cXmsVamsbw%3D 18456347 (Pubitemid 351694357)
14. K Kamata M Mitsuya T Nishimura J Eiki Y Nagata 2004 Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase Structure 12 429 438 10.1016/j.str.2004.02.005 1:CAS:528:DC%2BD2cXitFKlu7s%3D 15016359 (Pubitemid 38353064)
15. WD Kohn CM Kay RS Hodges 1995 Protein destabilization by electrostatic repulsions in the two stranded alpha helical coiled/coil leucine zipper Protein Sci 4 237 250 1:CAS:528:DyaK2MXktFGmtrs%3D 7757012
16. DP Kumar A Tiwari R Bhatt 2004 Effect of pH on the stability and structure of yeast hexokinase A J Biol Chem 279 32093 32099 10.1074/jbc. M313449200 1:CAS:528:DC%2BD2cXmtVCiu78%3D 15145950 (Pubitemid 39014655)
17. PR Kuser S Krauchenco OA Antunes I Polikarpov 2004 The high resolution crystal structure of yeast hexokinase PII with the correct primary sequence provides new insights into the mechanism of action J Biol Chem 275 20814 20821 10.1074/jbc.M910412199
18. Lakowicz JR (1999) Principles of fluorescence spectroscopy, 2nd edn. Kluwer Academics/Plenum Publishers, New York
19. GI Makhatadze PL Privalov 1992 Protein interactions with urea and guanidium chloride: a calorimetric study J Mol Biol 226 491 505 10.1016/0022-2836(92)90963-K 1:CAS:528:DyaK3sXisFOk 1322462
20. G Mei A Venere M Burgonza P Vecchini N Rosato F Argo 1997 Role of quaternary structure in the stability of dimeric proteins: the case of ascorbate oxidase Biochemistry 36 10917 10922 10.1021/bi970614p 1:CAS:528: DyaK2sXlsVOgsLo%3D 9283082 (Pubitemid 27396247)
21. SK Misra V Bhakuni 2003 Unique holoenzyme dimers of the tetrameric enzyme E. coli methylenetetrahydrofolate reductase: characterization of structural features associated with modulation of the enzymes function Biochemistry 42 3921 3928 10.1021/bi0340200 1:CAS:528:DC%2BD3sXitVemtrs%3D 12667083 (Pubitemid 36402685)
22. Y Mochizuki 1981 Evolutionary aspects of lower deuterostomian hexokinases Comp Biochem Physiol 70B 745 751 1:CAS:528:DyaL38Xhtlymtbg%3D
23. OD Monera CM Kay RS Hodges 1994 Protein denaturation with guanidine hydrochloride or urea provides a different estimate of stability depending on the contributions of electrostatic interactions Protein Sci 3 1984 1991 10.1002/pro.5560031110 1:CAS:528:DyaK2MXivFGnu70%3D 7703845
24. AM Mulichak JE Wilson K Padmanabhan RM Garavito 1998 The structure of mammalian hexokinase I Nat Struct Biol 5 555 560 10.1038/811 1:CAS:528:DyaK1cXks1entLY%3D 9665168 (Pubitemid 28317730)
25. PK Nandi DR Robinson 1984 Effects of urea and guanidine hydrochloride on peptide and non-polar groups Biochemistry 23 6661 6668 10.1021/bi00321a058 1:CAS:528:DyaL2MXhvFymuw%3D%3D 6529576
26. CN Pace 1986 Determination and analysis of urea and guanidine hydrochloride denaturation curves Methods Enzymol 131 267 280
27. GR Parr GG Hammes 1975 Subunit dissociation and unfolding of rabbit muscle phosphofructokinase Biochemistry 14 1600 1605 10.1021/bi00679a009 1:CAS:528:DyaE2MXhs1KlurY%3D 123759
28. A Perczel K Park GD Fasman 1992 Deconvolution of the circular dichroism spectra of protein, the circular dichroism spectra of the antiparallel beta-sheet in proteins Proteins Struct Funct Genet 13 57 10.1002/prot.340130106 1:CAS:528:DyaK38Xkt1alu7c%3D 1594578
29. Phillips D, Blake CCF, Watson HC (eds) (1981) The enzymes of glycolysis: structure, activity and evolution. Philos Trans R Soc Lond B Biol Sci 293:1-214
30. JA Schellman 2002 Fifty years of solvent denaturation Biophys Chem 96 91 101 10.1016/S0301-4622(02)00009-1 1:CAS:528:DC%2BD38XktVCqtrY%3D 12034431 (Pubitemid 34548223)
31. Schmid FX (1997) Optical spectroscopy to characterize protein conformation and conformational changes. In: Creighton TE (ed) Protein structure: a practical approach. Oxford University Press, Oxford, pp 261-297
32. R Seckler R Janicke 1992 Protein folding and protein refolding FASEB J 6 2545 2552 1:CAS:528:DyaK38Xkt1ajsr0%3D 1592207
33. AR Singh S Joshi R Arya AM Kayastha KK Srivatava LM Tripathi JK Saxena 2008 Molecular cloning and characterization of Brugia malayi hexokinase Parasitol Int 57 354 361 10.1016/j.parint.2008.03.004 1:CAS:528: DC%2BD1cXnt1emtrw%3D 18499511
34. TA Steiz RJ Fletterick WF Anderson M Anderson Ch 1976 High resolution X ray structure of yeast hexokinase, an allosteric protein exhibiting a non-symmetric arrangement of subunits J Mol Biol 104 197 222 10.1016/0022-2836(76)90009-7
35. AG Tielens JM Heuvel HJ Mazijk JE Wilson CB Shoemaker 1994 The 50-kDa glucose 6-phosphate-sensitive hexokinase of Schistosoma mansoni J Biol Chem 269 24736 24741 1:CAS:528:DyaK2cXmt1Cktb8%3D 7929149
36. B Venkatesha JB Udgaonkar NA Rao HS Savithri 1998 Reversible unfolding of sheep liver tetrameric serine hydroxymethyl transferase Biochim Biophys Acta 1384 141 152 1:CAS:528:DyaK1cXisFamtrc%3D 9602099