Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain

Mechanisms of Development

Volumn 127, Issue 1-2, 2010, Pages 62-72

  Zhao, Lanying ^a   Saitsu, Hirotomo ^a   Sun, Xiangnan ^a   Shiota, Kohei ^a   Ishibashi, Makoto ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

BMP4; Cell death; Conditional knock out; Fgf15; Optic cup; Pax2 6; Proliferation; Smoothened; Sonic hedgehog; Vax1 2

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; FIBROBLAST GROWTH FACTOR; MEMBRANE PROTEIN; PROTEIN FGF15; PROTEIN RALDH2; PROTEIN RALDH3; PROTEIN VAX1; PROTEIN VAX2; RETINOIC ACID; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PAX2; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWNSTREAM PROCESSING; EMBRYO; ENHANCER REGION; EYE DEVELOPMENT; GENE EXPRESSION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; OPTIC DISK CUP; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SOMITE; UPREGULATION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 4; CELL DEATH; CELL MEMBRANE; CELL PROLIFERATION; DEVELOPMENTAL BIOLOGY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PROTEIN STRUCTURE, TERTIARY; RETINA; SIGNAL TRANSDUCTION; TIME FACTORS;

ERINACEIDAE; VERTEBRATA;

EID: 73649092717     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mod.2009.10.006     Document Type: Article

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