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Volumn 8, Issue 20, 2009, Pages 1952-1961

Elevated expression of nuclear Hsp90 in invasive breast tumors

Author keywords

Breast cancer; Breast tissue arrays; Chaperones; Hsp90; Immunostaining; p23

Indexed keywords

ESTROGEN RECEPTOR; HEAT SHOCK PROTEIN 90; PROTEIN P23;

EID: 73549122974     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.8.20.9639     Document Type: Article
Times cited : (32)

References (43)
  • 1
    • 4143153881 scopus 로고    scopus 로고
    • Hsp90: An emerging target for breast cancer therapy
    • Beliakoff J, Whitesell L. Hsp90: an emerging target for breast cancer therapy. Anticancer Drugs 2004; 15:651-62.
    • (2004) Anticancer Drugs , vol.15 , pp. 651-662
    • Beliakoff, J.1    Whitesell, L.2
  • 2
    • 0031873752 scopus 로고    scopus 로고
    • The 90-kDa Molecular Chaperone Family: Structure, Function, and Clinical Applications. A Comprehensive Review
    • Csermely P, Schnaider T, Soti C, Prohaszka Z, Nardai G. The 90-kDa Molecular Chaperone Family: Structure, Function, and Clinical Applications. A Comprehensive Review. Pharmacol Ther 1998; 79:129-68.
    • (1998) Pharmacol Ther , vol.79 , pp. 129-168
    • Csermely, P.1    Schnaider, T.2    Soti, C.3    Prohaszka, Z.4    Nardai, G.5
  • 5
    • 28144439948 scopus 로고    scopus 로고
    • HSP90: A Rising Star on the Horizon of Anticancer Targets
    • Dai C, Whitesell L. HSP90: A Rising Star on the Horizon of Anticancer Targets. Future Oncol 2005; 1:529-40.
    • (2005) Future Oncol , vol.1 , pp. 529-540
    • Dai, C.1    Whitesell, L.2
  • 6
    • 0033004686 scopus 로고    scopus 로고
    • Role of telomerase in cellular proliferation and cancer
    • Holt SE, Shay JW. Role of telomerase in cellular proliferation and cancer. J Cell Physiol 1999; 180:10-8.
    • (1999) J Cell Physiol , vol.180 , pp. 10-18
    • Holt, S.E.1    Shay, J.W.2
  • 8
    • 0029849363 scopus 로고    scopus 로고
    • Expression and roles of heat shock proteins in human breast cancer
    • Yano M, Naito Z, Tanaka S, Asano G. Expression and roles of heat shock proteins in human breast cancer. Jpn J Cancer Res 1996; 87:908-15.
    • (1996) Jpn J Cancer Res , vol.87 , pp. 908-915
    • Yano, M.1    Naito, Z.2    Tanaka, S.3    Asano, G.4
  • 10
    • 0042885973 scopus 로고    scopus 로고
    • The Hsp90 chaperone complex as a novel target for cancer therapy
    • Goetz MP, Toft DO, Ames MM, Erlichman C. The Hsp90 chaperone complex as a novel target for cancer therapy. Ann Oncol 2003; 14:1169-76.
    • (2003) Ann Oncol , vol.14 , pp. 1169-1176
    • Goetz, M.P.1    Toft, D.O.2    Ames, M.M.3    Erlichman, C.4
  • 11
    • 33746191768 scopus 로고    scopus 로고
    • Inhibitors of the HSP90 Molecular Chaperone: Current Status
    • Sharp S, Workman P. Inhibitors of the HSP90 Molecular Chaperone: Current Status. Adv in Cancer Research 2006; 95:248-323.
    • (2006) Adv in Cancer Research , vol.95 , pp. 248-323
    • Sharp, S.1    Workman, P.2
  • 12
    • 41149111451 scopus 로고    scopus 로고
    • The Hsp90 molecular chaperone: An open and shut case for treatment
    • Pearl LH, Prodromou C, Workman P. The Hsp90 molecular chaperone: an open and shut case for treatment. Biochem J 2008; 410:439-53.
    • (2008) Biochem J , vol.410 , pp. 439-453
    • Pearl, L.H.1    Prodromou, C.2    Workman, P.3
  • 13
    • 85099486499 scopus 로고    scopus 로고
    • Pacey S, Banerji U, Judson I, Workman P. Hsp90 inhibitors in the clinic. HEP 2006; 172:331-58.
    • Pacey S, Banerji U, Judson I, Workman P. Hsp90 inhibitors in the clinic. HEP 2006; 172:331-58.
  • 14
    • 15444368857 scopus 로고    scopus 로고
    • Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes
    • Björnström L, Sjöberg M. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol Endocrinol 2005; 19:833-42.
    • (2005) Mol Endocrinol , vol.19 , pp. 833-842
    • Björnström, L.1    Sjöberg, M.2
  • 15
    • 0032915424 scopus 로고    scopus 로고
    • Role for Hsp90-associated cochaperone p23 in estrogen receptor signal transduction
    • Knoblauch R, Garabedian MJ. Role for Hsp90-associated cochaperone p23 in estrogen receptor signal transduction. Mol Cell Biol 1999; 19:3748-59.
    • (1999) Mol Cell Biol , vol.19 , pp. 3748-3759
    • Knoblauch, R.1    Garabedian, M.J.2
  • 16
    • 33745821260 scopus 로고    scopus 로고
    • The cochaperone p23 differentially regulates estrogen receptor target genes and promotes tumor cell adhesion and invasion
    • Oxelmark E, Roth JM, Brooks PC, Braunstein SE, Schneider RJ, Garabedian MJ. The cochaperone p23 differentially regulates estrogen receptor target genes and promotes tumor cell adhesion and invasion. Mol Cell Biol 2006; 26:5205-13.
    • (2006) Mol Cell Biol , vol.26 , pp. 5205-5213
    • Oxelmark, E.1    Roth, J.M.2    Brooks, P.C.3    Braunstein, S.E.4    Schneider, R.J.5    Garabedian, M.J.6
  • 17
    • 0037020680 scopus 로고    scopus 로고
    • 2+-binding modulator protein involved in cell proliferation and in cell death
    • 2+-binding modulator protein involved in cell proliferation and in cell death. Biochim Biophys Acta 2002; 1600:68-73.
    • (2002) Biochim Biophys Acta , vol.1600 , pp. 68-73
    • Krebs, J.1    Saramaslani, P.2    Caduff, R.3
  • 18
    • 0346599157 scopus 로고    scopus 로고
    • Properties of the co-chaperone protein p23 erroneously attributed to ALG-2 (apoptosis-linked gene 2)
    • Mollerup J, Krogh TN, Nielson PF, Berchtold MW. Properties of the co-chaperone protein p23 erroneously attributed to ALG-2 (apoptosis-linked gene 2). FEBS Lett 2003; 555:478-82.
    • (2003) FEBS Lett , vol.555 , pp. 478-482
    • Mollerup, J.1    Krogh, T.N.2    Nielson, P.F.3    Berchtold, M.W.4
  • 20
    • 0028832028 scopus 로고
    • Stress-response (heat-shock) protein 90 expression in tumors of the central nervous system: An immunohistochemical study
    • Kato S, Morita T, Takenaka T, Kato M, Hirano A, Herz F, Ohama E. Stress-response (heat-shock) protein 90 expression in tumors of the central nervous system: an immunohistochemical study. Acta Neuropathol 1995; 89:184-8.
    • (1995) Acta Neuropathol , vol.89 , pp. 184-188
    • Kato, S.1    Morita, T.2    Takenaka, T.3    Kato, M.4    Hirano, A.5    Herz, F.6    Ohama, E.7
  • 21
    • 33845992568 scopus 로고    scopus 로고
    • Expression of major heat shock proteins in prostate cancer: Correlation with clinicopathological outcomes in patients undergoing radical prostatectomy
    • Kurahashi T, Miyake H, Hara I, Fujisawa M. Expression of major heat shock proteins in prostate cancer: correlation with clinicopathological outcomes in patients undergoing radical prostatectomy. J Urol 2007; 177(2):757-61.
    • (2007) J Urol , vol.177 , Issue.2 , pp. 757-761
    • Kurahashi, T.1    Miyake, H.2    Hara, I.3    Fujisawa, M.4
  • 22
    • 0034199865 scopus 로고    scopus 로고
    • Overexpression and localization of heat shock proteins mRNA in pancreatic carcinoma
    • Ogata M, Naito Z, Tanaka S, Moriyama Y, Asano G. Overexpression and localization of heat shock proteins mRNA in pancreatic carcinoma. J Nippon Med Sch 2000; 67:177-85.
    • (2000) J Nippon Med Sch , vol.67 , pp. 177-185
    • Ogata, M.1    Naito, Z.2    Tanaka, S.3    Moriyama, Y.4    Asano, G.5
  • 23
    • 33746658605 scopus 로고    scopus 로고
    • Heat shock protein expression in canine malignant mammary tumors
    • Romanucci M, Marinelli A, Sarli G, Della Salda L. Heat shock protein expression in canine malignant mammary tumors. BMC Cancer 2006; 6:171-82.
    • (2006) BMC Cancer , vol.6 , pp. 171-182
    • Romanucci, M.1    Marinelli, A.2    Sarli, G.3    Della Salda, L.4
  • 24
    • 0035874978 scopus 로고    scopus 로고
    • A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression
    • Akalin A, Elmore LW, Forsythe HL, Amaker BA, McCollum ED, Nelson PS, et al. A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression. Cancer Res 2001; 61:4791-6.
    • (2001) Cancer Res , vol.61 , pp. 4791-4796
    • Akalin, A.1    Elmore, L.W.2    Forsythe, H.L.3    Amaker, B.A.4    McCollum, E.D.5    Nelson, P.S.6
  • 25
    • 54549110143 scopus 로고    scopus 로고
    • Overexpression of telomerase-associated chaperone proteins in prostatic intraepithelial neoplasia and carcinomas
    • Elmore LW, Forsythe R, Forsythe H, Bright T, Nasim S, Endo K, Holt SE. Overexpression of telomerase-associated chaperone proteins in prostatic intraepithelial neoplasia and carcinomas. Oncology Rep 2008; 20:613-7.
    • (2008) Oncology Rep , vol.20 , pp. 613-617
    • Elmore, L.W.1    Forsythe, R.2    Forsythe, H.3    Bright, T.4    Nasim, S.5    Endo, K.6    Holt, S.E.7
  • 30
    • 33845651854 scopus 로고    scopus 로고
    • The 2003 Revised TNM Staging Systme for Breast Cancer: Results of Stage Re-classification on Survival and Future Comparisons among Stage Groups
    • Escobar PF, Patrick RJ, Rybicki LA, Weng DE, Crowe JP. The 2003 Revised TNM Staging Systme for Breast Cancer: Results of Stage Re-classification on Survival and Future Comparisons among Stage Groups. Ann Surg Oncol 2006; 14:143-7.
    • (2006) Ann Surg Oncol , vol.14 , pp. 143-147
    • Escobar, P.F.1    Patrick, R.J.2    Rybicki, L.A.3    Weng, D.E.4    Crowe, J.P.5
  • 31
    • 62749085753 scopus 로고    scopus 로고
    • Breast Cancer, Estrogen Receptor and Ligands
    • Bai A, Gust R. Breast Cancer, Estrogen Receptor and Ligands. Arch Pharm Chem Life Sci 2009; 342:133-49.
    • (2009) Arch Pharm Chem Life Sci , vol.342 , pp. 133-149
    • Bai, A.1    Gust, R.2
  • 32
    • 55949130920 scopus 로고    scopus 로고
    • The clinicopathologic characteristics and prognostic significance of triple-negativity in node-negative breast cancer
    • Rhee J, Han SW, Oh DY, Kim JH, Im SA, Han W, et al. The clinicopathologic characteristics and prognostic significance of triple-negativity in node-negative breast cancer. BMC Cancer 2008; 23:307-14.
    • (2008) BMC Cancer , vol.23 , pp. 307-314
    • Rhee, J.1    Han, S.W.2    Oh, D.Y.3    Kim, J.H.4    Im, S.A.5    Han, W.6
  • 33
    • 40749124091 scopus 로고    scopus 로고
    • Functioning of the Hsp90 machine in chaperoning checkpoint kinase 1 (Chk1) and the progesterone receptor (PR)
    • Felts SJ, Karnitz LM, Toft DO. Functioning of the Hsp90 machine in chaperoning checkpoint kinase 1 (Chk1) and the progesterone receptor (PR). Cell Stress Chaperones 2007; 12:353-63.
    • (2007) Cell Stress Chaperones , vol.12 , pp. 353-363
    • Felts, S.J.1    Karnitz, L.M.2    Toft, D.O.3
  • 34
    • 0141592432 scopus 로고    scopus 로고
    • Genetic dissection of p23, an Hsp90 cochaperone, reveals a distinct surface involved in estrogen receptor signaling
    • Oxelmark E, Knoblauch R, Arnal S, Su LF, Schapira M, Garabedian MJ. Genetic dissection of p23, an Hsp90 cochaperone, reveals a distinct surface involved in estrogen receptor signaling. J Biol Chem 2003; 278:36547-55.
    • (2003) J Biol Chem , vol.278 , pp. 36547-36555
    • Oxelmark, E.1    Knoblauch, R.2    Arnal, S.3    Su, L.F.4    Schapira, M.5    Garabedian, M.J.6
  • 35
    • 32944482243 scopus 로고    scopus 로고
    • Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy
    • Cui X, Schiff R, Arpino G, Osborne CK, Lee AV. Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy. J Clin Oncol 2005; 23:7721-35.
    • (2005) J Clin Oncol , vol.23 , pp. 7721-7735
    • Cui, X.1    Schiff, R.2    Arpino, G.3    Osborne, C.K.4    Lee, A.V.5
  • 36
    • 0029781863 scopus 로고    scopus 로고
    • Loss of estrogen receptor in recurrent breast cancer is associated with poor response to endocrine therapy
    • Kuukasjärvi T, Kononen J, Helin H, Holli K, Isola J. Loss of estrogen receptor in recurrent breast cancer is associated with poor response to endocrine therapy. J Clin Oncol 1996; 14:2584-9.
    • (1996) J Clin Oncol , vol.14 , pp. 2584-2589
    • Kuukasjärvi, T.1    Kononen, J.2    Helin, H.3    Holli, K.4    Isola, J.5
  • 37
    • 0037501319 scopus 로고    scopus 로고
    • The estrogen receptor: A model for molecular medicine
    • Jensen EV, Jordan VC. The estrogen receptor: a model for molecular medicine. Clin Cancer Res 2003; 9:1980-9.
    • (2003) Clin Cancer Res , vol.9 , pp. 1980-1989
    • Jensen, E.V.1    Jordan, V.C.2
  • 38
    • 0037237481 scopus 로고    scopus 로고
    • Breast cancer endocrine resistance: How growth factor signaling and estrogen receptor coregulators modulate response
    • Schiff R, Massarweh S, Shou J, Osborne CK. Breast cancer endocrine resistance: how growth factor signaling and estrogen receptor coregulators modulate response. Clin Cancer Res 2003; 9:447-54.
    • (2003) Clin Cancer Res , vol.9 , pp. 447-454
    • Schiff, R.1    Massarweh, S.2    Shou, J.3    Osborne, C.K.4
  • 39
    • 8544226964 scopus 로고    scopus 로고
    • Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer
    • Leu YW, Yan PS, Fan M, Jin VX, Liu JC, Curran EM, et al. Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer. Cancer Res 2004; 64:8184-92.
    • (2004) Cancer Res , vol.64 , pp. 8184-8192
    • Leu, Y.W.1    Yan, P.S.2    Fan, M.3    Jin, V.X.4    Liu, J.C.5    Curran, E.M.6
  • 40
    • 0021328482 scopus 로고
    • Multiple progesterone receptor assays in human breast cancer
    • Gross GE, Clark GM, Chamness GC, McGuire WL. Multiple progesterone receptor assays in human breast cancer. Cancer Res 1984; 44:836-40.
    • (1984) Cancer Res , vol.44 , pp. 836-840
    • Gross, G.E.1    Clark, G.M.2    Chamness, G.C.3    McGuire, W.L.4
  • 41
    • 0033015682 scopus 로고    scopus 로고
    • Absence of progesterone receptor associated with secondary breast cancer in postmenopausal women
    • Balleine RL, Earl MJ, Greenberg ML, Clarke CL. Absence of progesterone receptor associated with secondary breast cancer in postmenopausal women. Br J Cancer 1999; 79:1564-71.
    • (1999) Br J Cancer , vol.79 , pp. 1564-1571
    • Balleine, R.L.1    Earl, M.J.2    Greenberg, M.L.3    Clarke, C.L.4
  • 42
    • 0028156864 scopus 로고
    • In vivo functional protein-protein interaction: Nuclear targeted hsp90 shifts cytoplasmic steroid receptor mutants into the nucleus
    • Kang KI, Devin J, Cadepond F, Jibard N, Guiochon-Mantel A, Baulieu E, Catelli M. In vivo functional protein-protein interaction: nuclear targeted hsp90 shifts cytoplasmic steroid receptor mutants into the nucleus. Proc Natl Acad Sci USA 1994; 91:340-4.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 340-344
    • Kang, K.I.1    Devin, J.2    Cadepond, F.3    Jibard, N.4    Guiochon-Mantel, A.5    Baulieu, E.6    Catelli, M.7
  • 43
    • 33744961514 scopus 로고    scopus 로고
    • FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus
    • Wesche J, Małecki J, Wiedłocha A, Skjerpen CS, Claus P, Olsnes S. FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus. J Biol Chem 2006; 281:11405-12.
    • (2006) J Biol Chem , vol.281 , pp. 11405-11412
    • Wesche, J.1    Małecki, J.2    Wiedłocha, A.3    Skjerpen, C.S.4    Claus, P.5    Olsnes, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.