Non-neuronal nicotinic acetylcholine receptors: Cholinergic regulation of the immune processes

Neurophysiology

Volumn 39, Issue 4-5, 2007, Pages 264-271

  Skok, M V ^a  

^a PALLADIN INSTITUTE OF BIOCHEMISTRY   (Ukraine)

Author keywords

Cholinergic regulation; Immune system; Lymphocytes; Nicotinic acetylcholine receptor

Indexed keywords

EID: 73449104601     PISSN: 00902977     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11062-007-0037-2     Document Type: Conference Paper

References (81)

1. J. Lindstrom, "Neuronal nicotinic acetylcholine receptors," in: Ion Channels, Vol. 4, T. Narahashi (ed.), Plenum Press, New York (1996), pp. 377-449.
2. V. I. Skok 2002 Nicotinic acetylcholine receptors in autonomic ganglia Autonomic Neurosci. Basic Clin. 97 1 11 10.1016/S1566-0702(01)00386-1 1:CAS:528:DC%2BD38XktlOksLs%3D (Pubitemid 34240050)
3. D. Paterson A. Nordberg 2000 Neuronal nicotinic receptors in the human brain Prog. Neurobiol. 61 75 111 10759066 10.1016/S0301-0082(99)00045-3 1:CAS:528:DC%2BD3cXisValurc%3D (Pubitemid 30100404)
4. J. Arrendolo V. T. Nguen A. I. Chernyavsky, et al. 2003 Functional role of α7 nicotinic receptors in physiological control of cutaneous homeostasis Life Sci. 72 2063 2067 10.1016/S0024-3205(03)00084-5 1:CAS:528:DC%2BD3sXhs1Clt7k%3D (Pubitemid 36298948)
5. B. M. Conti-Fine D. Navaneetham S. Lei A. D. J. Maus 2000 Neuronal nicotinic receptors in non-neuronal cells: new mediators of tobacco toxicity? Eur. J. Pharmacol. 393 279 294 10771024 10.1016/S0014-2999(00)00036-4 1:CAS:528:DC%2BD3cXisFKjs7c%3D (Pubitemid 30193427)
6. A. Cormier Y. Paas R. Zini, et al. 2004 Long-term exposure to nicotine modulates the level and activity of acetylcholine receptors in white blood cells of smokers and model mice Mol. Pharmacol. 66 1 7 10.1124/mol.104.000463 1:CAS:528:DC%2BD2cXhtVOit7nN (Pubitemid 39564798)
7. K. Kawashima T. Fujii 2003 The lymphocytic cholinergic system and its biological function Life Sci. 72 2101 2109 12628464 10.1016/S0024-3205(03)00068- 7 1:CAS:528:DC%2BD3sXhs1CltLo%3D (Pubitemid 36298953)
8. H. Wang M. Yu C. A. Amella, et al. 2003 Nicotinic receptor α7 subunit is an essential regulator of inflammation Nature 421 384 388 12508119 10.1038/nature01339 1:CAS:528:DC%2BD3sXlsVantA%3D%3D (Pubitemid 36157937)
9. P. Bennekou 1993 The voltage-gated non-selective cation channel from human red cells is sensitive to acetylcholine Biochim. Biophys. Acta 1147 165 167 7682111 10.1016/0005-2736(93)90328-W 1:CAS:528:DyaK3sXit1Kgsr8%3D (Pubitemid 23104901)
10. I. K. Wessler C. J. Kirkpatrick K. Racke 1999 The cholinergic 'pitfall': acetylcholine, a universal cell molecule in biological systems, including humans Clin. Exp. Pharm. Physiol. 26 198 205 10.1046/j.1440-1681.1999.03016.x 1:CAS:528:DyaK1MXhs12rurg%3D (Pubitemid 29128015)
11. K. Bamel S. C. Gupta R. Gupta 2007 Acetylcholine causes rooting in leaf explants of in vitro raised tomato (Lycopersicon esculentum Miller) seedlings Life Sci. 80 s.24/25 2393 2396 17328922 10.1016/j.lfs.2007.01.039 1:CAS:528:DC%2BD2sXmtVehtbk%3D (Pubitemid 46818272)
12. N. Bocquet L. Prado de Carvalo J. Cartaud, et al. 2007 A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family Nature 445 116 119 17167423 10.1038/nature05371 1:CAS:528:DC%2BD2sXhsFOmtg%3D%3D (Pubitemid 46067312)
13. T. Strom A. Sytkowski C. Carpenter J. Merrill 1974 Cholinergic augmentation of lymphocyte-mediated cytotoxicity. A study of the cholinergic receptor of cytotoxic T lymphocytes Proc. Natl. Acad. Sci. USA 74 1330 1333 10.1073/pnas.71.4.1330
14. D. Richman B. Arnason 1979 Nicotinic acetylcholine receptor: evidence for a functionally distinct receptor on human lymphocytes Proc. Natl. Acad. Sci. USA 76 4632 4635 291991 10.1073/pnas.76.9.4632 1:CAS:528:DyaE1MXlvFShs78%3D
15. E. Hellstrom-Lindhal A. Nordberg 1996 Muscarinic receptor subtypes in subpopulations of human blood mononuclear cells as analyzed by RT-PCR technique J. Neuroimmunol. 68 139 144 10.1016/0165-5728(96)00079-3 (Pubitemid 26279256)
16. C. Hiemke M. Stolp S. Reuss, et al. 1996 Expression of alpha subunit genes of nicotinic acetylcholine receptors in human lymphocytes Neurosci. Lett. 214 171 174 8878111 10.1016/0304-3940(96)12908-6 1:CAS:528:DyaK28XlsFyhsr8%3D (Pubitemid 26284459)
17. K. Z. Sato T. Fujii Y. Watanabe, et al. 1999 Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines Neurosci. Lett. 266 17 20 10336173 10.1016/S0304-3940(99)00259-1 1:CAS:528:DyaK1MXjtF2qurY%3D (Pubitemid 29219745)
18. S. Toyabe T. Iiai M. Fukuda, et al. 1997 Identification of nicotinic acetylcholine receptors on lymphocytes in the periphery as well as thymus in mice Immunology 92 201 205 9415027 10.1046/j.1365-2567.1997.00323.x 1:CAS:528:DyaK2sXmsVensrg%3D
19. J. Lindstrom 2002 Autoimmune diseases involving nicotinic receptors J. Neurobiol. 53 4 656 665 12436428 10.1002/neu.10106 1:CAS:528: DC%2BD38Xps1Kltrw%3D (Pubitemid 35375594)
20. W. K. Engel J. L. Trotter D. E. McFarlin C. L. McIntosh 1977 Thymic epithelial cells contain acetylcholine receptor Lancet 1 1310 1311 68406 10.1016/S0140-6736(77)91343-5 1:STN:280:DyaE2s7ptFGguw%3D%3D
21. T. Kirchner S. Tzartos F. Hoppe, et al. 1986 Acetylcholine receptor-related antigenic determinants in tumor-free thymuses and thymic epithelial tumors Am. J. Pathol. 130 268 274
22. S. Kawanami H. Kamei J. Otta, et al. 1987 Acetylcholine receptor-like protein from human thymoma associated with myasthenia gravis J. Neurol. 234 207 211 3612190 10.1007/BF00618251 1:CAS:528:DyaL2sXltlagur8%3D
23. K. I. Geuder A. Marx V. Witzmann, et al. 1992 Pathogenic significance of fetal-type acetylcholine receptors on thymic myoid cells in myasthenia gravis Dev. Immunol. 2 69 75 1643420 1:STN:280:DyaK38zltlKntg%3D%3D
24. A. Wakkach T. Guyon C. Bruand, et al. 1996 Expression of acetylcholine receptor genes in human thymic epithelial cells-implications for myasthenia gravis J. Immunol. 157 3752 3760 8871679 1:CAS:528:DyaK28Xmtlakur8%3D
25. D. Navaneetham A. S. Penn J. F. Howard B. M. Conti-Fine 2001 Human thymuses express incomplete sets of muscle acetylcholine receptor subunit transcripts that seldom include the δ subunit Muscle Nerve 24 203 210 11180203 10.1002/1097-4598(200102)24:2<203::AID-MUS50>3.0.CO;2-F 1:CAS:528:DC%2BD3MXhtVeksb4%3D (Pubitemid 32105816)
26. M. Mihovilovic A. Roses 1993 Expression of α3, α5 and β4 neuronal acetylcholine receptor subunit transcripts in normal and myasthenia gravis thymus. Identification of thymocytes expressing the α3 transcripts J. Immunol. 151 6517 6524 8245482 1:CAS:528:DyaK2cXivFamsw%3D%3D
27. D. Navaneetham A. Penn J. Howard Jr. B. Conti-Fine 1997 Expression of the α7 subunit of the nicotinic acetylcholine receptor in normal and myasthenic human thymuses Cell. Mol. Biol. 43 433 442 9193799 1:CAS:528:DyaK2sXjsl2nurs%3D
28. W. Maslinski H. Laskowska-Bozek J. Ryzewski 1992 Nicotinic receptors of rat lymphocytes during adjuvant polyarthritis J. Neurosci. Res. 31 336 340 1573684 10.1002/jnr.490310215 1:CAS:528:DyaK38XhslaitLo%3D
29. F. Lebargy K. Benhammou D. Morin, et al. 1996 Tobacco smoking induces expression of very high-affinity nicotine-binding sites on blood polymorphonuclear cells Am. J. Respir. Crit. Care Med. 153 1056 1063 8630545 1:STN:280:DyaK287osFCisA%3D%3D
30. 3H]-Nicotine binding in peripheral blood cells of smokers is correlated with the number of cigarettes smoked per day Neuropharmacology 39 2818 2829 11044752 10.1016/S0028-3908(00)00153-2 1:CAS:528:DC%2BD3cXntlGqtro%3D (Pubitemid 30753053)
31. 2+ concentration in human lymphocytes Neuroimmunomodulation 3 247 253 9094447 1:CAS:528: DyaK2sXisVaktro%3D
32. 2+ stores J. Pharmacol. Exp. Ther. 293 166 171 10734166 1:CAS:528:DC%2BD3cXkvFGhtb4%3D
33. H. Peng R. L. Ferris T. Matthews, et al. 2004 Characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) and alpha (alpha) 10 (CHRNA10) in lymphocytes Life Sci. 76 3 263 280 15531379 10.1016/j.lfs.2004.05.031 1:CAS:528:DC%2BD2cXpsFWrtLc%3D (Pubitemid 39452910)
34. M. V. Skok E. N. Kalashnik L. N. Koval, et al. 2003 Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines Mol. Pharmacol. 64 885 889 14500745 10.1124/mol.64.4.885 1:CAS:528: DC%2BD3sXnslGrurY%3D (Pubitemid 37153057)
35. M. V. Skok R. Grailhe J.-P. Changeux 2005 Nicotinic receptors regulate B lymphocyte activation and immune response Eur. J. Pharmacol. 517 246 251 15963492 10.1016/j.ejphar.2005.05.011 1:CAS:528:DC%2BD2MXmtFGitr0%3D (Pubitemid 40977902)
36. M. V. Skok R. Grailhe F. Agenes J.-P. Changeux 2007 The role of nicotinic receptors in B-lymphocyte development and activation Life Sci. 80 2334 2336 17363009 10.1016/j.lfs.2007.02.005 1:CAS:528:DC%2BD2sXmtVehtLs%3D (Pubitemid 46818278)
37. M. V. Skok R. Grailhe F. Agenes J.-P. Changeux 2006 The role of nicotinic acetylcholine receptors in lymphocyte development J. Neuroimmunol. 171 86 98 16253349 10.1016/j.jneuroim.2005.09.011 1:CAS:528:DC%2BD28Xkt12q (Pubitemid 41832280)
38. P. G. Holt D. Keast 1977 Environmentally induced changes in immunological function: acute and chronic effects of inhalation of tobacco smoke and other atmospheric contaminants in man and experimental animals Bacteriol. Rev. 41 205 216 405003 1:CAS:528:DyaE2sXktVSksbw%3D
39. J. S. MacKenzie I. H. MacKenzie P. G. Holt 1976 The effect of cigarette smoking on susceptibility to epidemic influenza and on serological responses to live attenuated and killed subunit influenza vaccines J. Hyg. (Lond.) 77 409 417 1:STN:280:DyaE2s%2Fnt1Oisw%3D%3D
40. S. N. Goud A. M. Kaplan B. Subbarao 1992 Effects of cigarette smoke on the antibody response to thymic independent antigens from different lymphoid tissues of mice Arch. Toxicol. 66 164 169 1497478 10.1007/BF01974009 1:CAS:528:DyaK38Xmt1yhtb8%3D
41. M. L. Sopori S. Cherian R. Chilukuri G. M. Shopp 1989 Cigarette smoke causes inhibition of the immune response to intratracheally administered antigens Toxicol. Appl. Pharmacol. 97 489 499 2609346 10.1016/0041-008X(89) 90254-8 1:CAS:528:DyaL1MXitVOlt7o%3D (Pubitemid 19094965)
42. S. M. Savage L. A. Donaldson S. Cherian, et al. 1991 Effects of cigarette smoke on the immune response. II. Chronic exposure to cigarette smoke inhibits surface immunoglobulin-mediated responses in B cells Toxicol. Appl. Pharmacol. 111 523 529 1746027 10.1016/0041-008X(91)90256-E 1:CAS:528:DyaK38XnvVentQ%3D%3D
43. Y. Geng S. M. Savage L. J. Johnson, et al. 1995 Effects of nicotine on the immune response. I. Chronic exposure to nicotine impairs antigen receptor-mediated signal transduction in lymphocytes Toxicol. Appl. Pharmacol. 135 268 278 8545837 10.1006/taap.1995.1233 1:CAS:528:DyaK28XhvFSnsQ%3D%3D (Pubitemid 26031878)
44. A. A. Frazer-Abel S. Baksh S. P. Fosmire, et al. 2004 Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells J. Pharmacol. Exp. Ther. 311 2 58 69 10.1124/jpet.104.070060 1:CAS:528:DC%2BD2cXptVKru7s%3D (Pubitemid 39391565)
45. Y. Geng S. M. Savage S. Razani-Boroujerdi M. L. Sopori 1996 Effects of nicotine on the immune response. II. Chronic nicotine treatment induces T cell anergy J. Immunol. 156 2384 2390 8786295 1:CAS:528:DyaK28XhvVGlsbY%3D
46. S. P. Singh R. Kalra P. Puttfarcken, et al. 2000 Acute and chronic nicotine exposures modulate the immune system through different pathways Toxicol. Appl. Pharmacol. 164 65 72 10739745 10.1006/taap.2000.8897 1:CAS:528:DC%2BD3cXitVais70%3D (Pubitemid 30198545)
47. P. Andersen D. F. Pedersen B. Bach G. J. Bonde 1982 Serum immunoglobulins in smokers and non-smokers Clin. Exp. Immunol. 47 467 473 7042142 1:STN:280:DyaL387osFWgtA%3D%3D
48. B. Burrows M. Halonen R. A. Barbee M. D. Lebowitz 1981 The relationship of serum immunoglobulin E to cigarette smoking Am. Rev. Resp. Dis. 124 523 525 7305105 1:CAS:528:DyaL3MXmtFKhsbs%3D
49. D. A. Hughes P. L. Haslam P. J. Townsend M. Turner-Warwick 1985 Numerical and functional alteration in circulatory lymphocytes in cigarette smokers Clin. Exp. Immunol. 61 459 466 2931227 1:STN:280:DyaL28%2Fgt12ntw%3D%3D
50. C. Heeschen J. J. Jang M. Weis, et al. 2001 Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis Nat. Med. 7 775 777 10.1038/89961 1:CAS:528:DC%2BD3MXltVagt70%3D (Pubitemid 32691639)
51. I. Rinner A. Globerson K. Kawashima, et al. 1999 A possible role for acetylcholine in the dialogue between thymocytes and thymic stroma Neuroimmunomodulation 6 51 55 9876235 10.1159/000026364 1:CAS:528: DyaK1MXmtlCjtg%3D%3D (Pubitemid 29049158)
52. K. H. Costenbader E. W. Karlson 2005 Cigarette smoking and systemic lupus erythematosus: a smoking gun? Autoimmunity 38 7 541 547 16373259 10.1080/08916930500285758 1:CAS:528:DC%2BD2MXhtlCnur7N (Pubitemid 43101788)
53. M. E. Gershwin C. Selmi H. J. Worman, et al. 2005 Risk factors and comorbidities in primary biliary cirrhosis: a controlled interview-based study of 1032 patients Hepatology 42 5 1194 1202 16250040 10.1002/hep.20907 (Pubitemid 43112687)
54. M. M. Ward M. H. Weisman J. C. Davis Jr. J. D. Reveille 2005 Risk factors for functional limitations in patients with long-standing ankylosing spondylitis Arthritis Rheumatol. 53 5 710 717 10.1002/art.21444 (Pubitemid 41463836)
55. M. M. Loembe J. Lamoureux N. Deslauriers, et al. 2001 Lack of CD40-dependent B-cell proliferation in B lymphocytes isolated from patients with persistent polyclonal B-cell lymphocytosis Br. J. Haematol. 113 699 705 11380461 10.1046/j.1365-2141.2001.02806.x 1:CAS:528:DC%2BD3MXkvFehtr8%3D (Pubitemid 32524394)
56. C. M. Mills 1993 Smoking and skin disease Int. J. Dermatol. 32 864 865 8125685 10.1111/j.1365-4362.1993.tb01399.x 1:STN:280:DyaK2c7ntFCnug%3D%3D
57. M. L. Sopori W. Kozak S. M. Savage, et al. 1998 Effect of nicotine on the immune system: possible regulation of immune responses by central and peripheral mechanisms Psychoneuroendocrinology 23 189 204 9621398 10.1016/S0306-4530(97)00076-0 1:CAS:528:DyaK1cXjslWiu7w%3D (Pubitemid 28248471)
58. G. P. Brown G. K. Iwamoto M. M. Monick G. W. Hunninghake 1989 Cigarette smoking decreases interleukin-1 release by human alveolar macrophages Am. J. Physiol. 256 C260 C264 2784033 1:CAS:528:DyaL1MXhsV2luro%3D
59. L. V. Borovikova S. Ivanova M. Zhang, et al. 2000 Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin Nature 405 458 462 10839541 10.1038/35013070 1:CAS:528:DC%2BD3cXjslyltbY%3D (Pubitemid 30367422)
60. K. Aoshiba A. Nagai K. Yasui Konno 1996 Nicotine prolongs neutrophil survival by suppressing apoptosis J. Lab. Clin. Med. 127 186 194 8636647 10.1016/S0022-2143(96)90077-3 1:CAS:528:DyaK28XhsFSitrg%3D (Pubitemid 2626801)
61. N. Serobyan S. Jagannathan I. Orlovskaya, et al. 2007 The cholinergic system is involved in regulation of the development of the hematopoietic system Life Sci. 80 2352 2360 17512954 10.1016/j.lfs.2007.04.017 1:CAS:528: DC%2BD2sXmtVehtLc%3D (Pubitemid 46818290)
62. S. Y. Felten and D. L. Felten, "Innervation of lymphoid tissue," in: Psychoneuroimmunology, R. Ader, D. L. Felten, and D. Cohen (eds.), Academic Press, San Diego (1991), pp. 21-118.
63. F. Mignini V. Strecioni F. Amenta 2003 Autonomic innervation of immune organs and neuroimmune modulation Auton. Autacoid. Pharmacol. 23 1 25 14565534 10.1046/j.1474-8673.2003.00280.x 1:CAS:528:DC%2BD3sXmt1Gns74%3D (Pubitemid 36917752)
64. V. M. Sanders A. P. Kohm 2002 Sympathetic nervous system interaction with the immune system Int. Rev. Neurobiol. 52 17 41 12498099 1:CAS:528: DC%2BD3sXhtVyhsbo%3D 10.1016/S0074-7742(02)52004-3
65. Y. Qiu Y. Peng J. Wang 1996 Immunoregulatory role of neurotransmitters Adv. Neuroimmunol. 6 223 231 8968422 10.1016/S0960-5428(96)00018-6 1:CAS:528:DyaK2sXlvFGguw%3D%3D
66. M. Artico S. Bosco C. Cavallotti, et al. 2002 Noradrenergic and cholinergic innervation of the bone marrow Int. J. Mol. Med. 10 77 80 12060854 1:CAS:528:DC%2BD38XltlOkuro%3D
67. U. Singh J. Fatani 1988 Thymic lymphopoiesis and cholinergic innervations Thymus 11 3 13 3257832 1:STN:280:DyaL1c7ks1WrtA%3D%3D
68. V. N. Chernigovskiy, S. Yu. Shehter, and A. Ya. Yaroshevskiy, Regulation of Hematopoiesis [in Russian], Nauka Publishing House, Leningrad (1967).
69. A. Antonica E. Magni L. Mearini N. Paolocci 1994 Vagal control of lymphocyte release from rat thymus J. Auton. Nerv. Sys. 48 187 197 10.1016/0165-1838(94)90047-7 1:STN:280:DyaK2M%2Flt1ejtg%3D%3D (Pubitemid 24210344)
70. D. L. Bellinger D. Lorton R. W. Hamill, et al. 1993 Acetylcholinesterase staining and choline acetyltransferase activity in the young adult rat spleen: lack of evidence for cholinergic innervations Brain, Behav., Immunity 7 191 204 10.1006/brbi.1993.1021 1:CAS:528:DyaK2cXhvVelsL0%3D (Pubitemid 23302158)
71. K. S. Lips C. Volk B. M. Schmit, et al. 2005 Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium Am. J. Respir. Cell. Mol. Biol. 33 79 88 15817714 10.1165/rcmb.2004-0363OC 1:CAS:528:DC%2BD2MXmsVSiu7s%3D (Pubitemid 40961017)
72. T. Schlereth F. Birklein K. an Haack, et al. 2006 In vivo release of non-neuronal acetylcholine from the human skin as measured by dermal microdialysis: effect of botulinum toxin Br. J. Pharmacol. 147 183 187 16273117 10.1038/sj.bjp.0706451 1:CAS:528:DC%2BD28Xmtlynsw%3D%3D (Pubitemid 43151566)
73. M. Yoshida A. Inadome Y. Maeda, et al. 2006 Non-neuronal cholinergic system in human bladder urothelium Urology 67 2 425 430 16461116 10.1016/j.urology.2005.08.014 (Pubitemid 43189886)
74. I. Rinner K. Kawashima K. Schauenstein 1998 Rat lymphocytes produce and secrete acetylcholine in dependence of differentiation and activation J. Neuroimmunol. 81 31 37 9521603 10.1016/S0165-5728(97)00155-0 1:CAS:528:DyaK1cXhtVWlsrg%3D (Pubitemid 28248181)
75. T. Fujii Y. Takada-Takatori K. Kawashima 2007 Roles played by lymphocyte function-associated antigen-1 in the regulation of lymphocytic cholinergic activity Life Sci. 80 s.24/25 2320 2324 17289088 10.1016/j.lfs.2007.01.012 1:CAS:528:DC%2BD2sXmtVehtLw%3D (Pubitemid 46818266)
76. Y. Zhou E. Deneris R. E. Zigmond 2001 Nicotinic acetylcholine receptor subunit proteins alpha7 and beta4 decrease in the superior cervical ganglion after axotomy J. Neurobiol. 46 3 178 192 11169504 10.1002/1097-4695(20010215)46: 3<178::AID-NEU1001>3.0.CO;2-C 1:CAS:528:DC%2BD3MXhtFKnuro%3D (Pubitemid 32105830)
77. R. S. Broide F. M. Leslie 1999 The alpha7 nicotinic acetylcholine receptor in neuronal plasticity Mol. Neurobiol. 20 1 16 10595869 10.1007/BF02741361 1:CAS:528:DC%2BD3cXhtFej
78. M. Alkondon E. F. R. Pereira W. S. Cortes, et al. 1997 Choline is a selective agonist of α7 nicotinic acetylcholine receptors in the rat brain neurons Eur. J. Neurosci. 9 2734 2742 9517478 10.1111/j.1460-9568.1997.tb01702. x 1:STN:280:DyaK1c7ns1Kmtw%3D%3D (Pubitemid 28082962)
79. J. Arredondo A. I. Chernyavsky R. J. Webber S. A. Grando 2005 Biological effects of SLURP-1 on human keratinocytes J. Invest. Dermatol. 125 6 1236 1241 16354194 10.1111/j.0022-202X.2005.23973.x 1:CAS:528:DC%2BD28XjvFKqtA%3D%3D
80. J. Arredondo A. I. Chernyavsky D. L. Jolkovsky, et al. 2006 SLURP-2: A novel cholinergic signaling peptide in human mucocutaneous epithelium J. Cell. Physiol. 208 1 238 245 16575903 10.1002/jcp.20661 1:CAS:528:DC%2BD28XmtVagu74%3D (Pubitemid 43849010)
81. Y. Moriwaki K. Yoshikawa H. Fukuda, et al. 2007 Immune system expression of SLURP-1 and SLURP-2, two endogenous nicotinic acetylcholine receptor ligands Life Sci. 80 s.24/25 2365 2368 17286989 10.1016/j.lfs.2006.12.028 1:CAS:528:DC%2BD2sXmtVehtb8%3D (Pubitemid 46818253)