The role of osteopontin in d-galactosamine-induced liver injury in genetically obese mice

Toxicology and Applied Pharmacology

Volumn 242, Issue 3, 2010, Pages 344-351

  Kwon, Hyo Jung ^a,b   Won, Young Suk ^a   Yoon, Won Kee ^a   Nam, Ki Hoan ^a   Kim, Dae Yong ^b   Kim, Hyoung Chin ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

d Galactosamine; Interleukin 12; Interleukin 18; Obese mice; Osteopontin

Indexed keywords

GALACTOSAMINE; INTERLEUKIN 12; INTERLEUKIN 18; LIVER ENZYME; OSTEOPONTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; HISTOPATHOLOGY; IMMUNOMODULATION; INFLAMMATION; INFLAMMATORY CELL; LIVER CELL; LIVER INJURY; MACROPHAGE MIGRATION; MOUSE MUTANT; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; UPREGULATION; WILD TYPE;

ANIMALS; CYTOKINES; DRUG-INDUCED LIVER INJURY; GALACTOSAMINE; HEPATOCYTES; INFLAMMATION; INTERLEUKIN-12; INTERLEUKIN-18; LIVER; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; OSTEOPONTIN; UP-REGULATION;

MUS;

EID: 73449095193     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.11.006     Document Type: Article

References (35)

1. Apte U.M., Banerjee A., McRee R., Wellberg E., and Ramaiah S.K. Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis. Toxicol. Appl. Pharmacol. 207 (2005) 25-38
2. Ashkar S., Weber G.F., Panoutsakopoulou V., Sanchirico M.E., Jansson M., Zawaideh S., Rittling S.R., Denhardt D.T., Glimcher M.J., and Cantor H. Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science 287 (2000) 860-864
3. Banerjee A., Apte U.M., Smith R., and Ramaiah S.K. Higher neutrophil infiltration mediated by osteopontin is a likely contributing factor to the increased susceptibility of females to alcoholic liver disease. J. Pathol. 208 (2006) 473-485
4. Banerjee A., Burghardt R.C., Johnson G.A., White F.J., and Ramaiah S.K. The temporal expression of osteopontin (SPP-1) in the rodent model of alcoholic steatohepatitis: a potential biomarker. Toxicol. Pathol. 34 (2006) 373-384
5. Banerjee A., Lee J.H., and Ramaiah S.K. Interaction of osteopontin with neutrophil alpha(4)beta(1) and alpha(9)beta(1) integrins in a rodent model of alcoholic liver disease. Toxicol. Appl. Pharmacol. 233 (2008) 238-246
6. DeAngelis R.A., Markiewski M.M., Taub R., and Lambris J.D. A high-fat diet impairs liver regeneration in C57BL/6 mice through overexpression of the NF-kappaB inhibitor. IkappaBalpha. Hepatology 42 (2005) 1148-1157
7. Diehl A.M. Nonalcoholic steatohepatitis. Semin. Liver Dis. 19 (1999) 221-229
8. Faggioni R., Fantuzzi G., Gabay C., Moser A., Dinarello C.A., Feingold K.R., and Grunfeld C. Leptin deficiency enhances sensitivity to endotoxin-induced lethality. Am. J. Physiol. 276 (1999) R136-142
9. Friedman J.M., and Halaas J.L. Leptin and the regulation of body weight in mammals. Nature 395 (1998) 763-770
10. Gomez-Ambrosi J., Catalan V., Ramirez B., Rodriguez A., Colina I., Silva C., Rotellar F., Mugueta C., Gil M.J., Cienfuegos J.A., Salvador J., and Fruhbeck G. Plasma osteopontin levels and expression in adipose tissue are increased in obesity. J. Clin. Endocrinol. Metab. 92 (2007) 3719-3727
11. Hourigan L.F., Macdonald G.A., Purdie D., Whitehall V.H., Shorthouse C., Clouston A., and Powell E.E. Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis. Hepatology 29 (1999) 1215-1219
12. Ikejima K., Okumura K., Lang T., Honda H., Abe W., Yamashina S., Enomoto N., Takei Y., and Sato N. The role of leptin in progression of non-alcoholic fatty liver disease. Hepatol. Res. 33 (2005) 151-154
13. Ikejima S., Sasaki S., Sashinami H., Mori F., Ogawa Y., Nakamura T., Abe Y., Wakabayashi K., Suda T., and Nakane A. Impairment of host resistance to Listeria monocytogenes infection in liver of db/db and ob/ob mice. Diabetes 54 (2005) 182-189
14. Kawashima R., Mochida S., Matsui A., YouLuTu Z.Y., Ishikawa K., Toshima K., Yamanobe F., Inao M., Ikeda H., Ohno A., Nagoshi S., Uede T., and Fujiwara K. Expression of osteopontin in Kupffer cells and hepatic macrophages and Stellate cells in rat liver after carbon tetrachloride intoxication: a possible factor for macrophage migration into hepatic necrotic areas. Biochem. Biophys. Res. Commun. 256 (1999) 527-531
15. Kiefer F.W., Zeyda M., Todoric J., Huber J., Geyeregger R., Weichhart T., Aszmann O., Ludvik B., Silberhumer G.R., Prager G., and Stulnig T.M. Osteopontin expression in human and murine obesity: extensive local up-regulation in adipose tissue but minimal systemic alterations. Endocrinology 149 (2008) 1350-1357
16. Koh H.S., Matsui A., Mimura S., Inao M., Saitoh E., Ohno A., Nagoshi S., Yoshimoto T., Mochida S., and Fujiwara K. Increased cytoprotective function in the liver of transgenic mice expressing osteopontin in hepatocytes. Hepatol. Res. 32 (2005) 46-51
17. Lee G.H., Proenca R., Montez J.M., Carroll K.M., Darvishzadeh J.G., Lee J.I., and Friedman J.M. Abnormal splicing of the leptin receptor in diabetic mice. Nature 379 (1996) 632-635
18. Lorena D., Darby I.A., Gadeau A.P., Leen L.L., Rittling S., Porto L.C., Rosenbaum J., and Desmouliere A. Osteopontin expression in normal and fibrotic liver. Altered liver healing in osteopontin-deficient mice. J. Hepatol. 44 (2006) 383-390
19. Mancuso P., Gottschalk A., Phare S.M., Peters-Golden M., Lukacs N.W., and Huffnagle G.B. Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia. J. Immunol. 168 (2002) 4018-4024
20. Mimura S., Mochida S., Inao M., Matsui A., Nagoshi S., Yoshimoto T., and Fujiwara K. Massive liver necrosis after provocation of imbalance between Th1 and Th2 immune reactions in osteopontin transgenic mice. J. Gastroenterol. 39 (2004) 867-872
21. Moore S.I., Huffnagle G.B., Chen G.H., White E.S., and Mancuso P. Leptin modulates neutrophil phagocytosis of Klebsiella pneumoniae. Infect. Immun. 71 (2003) 4182-4185
22. Morimoto J., Inobe M., Kimura C., Kon S., Diao H., Aoki M., Miyazaki T., Denhardt D.T., Rittling S., and Uede T. Osteopontin affects the persistence of beta-glucan-induced hepatic granuloma formation and tissue injury through two distinct mechanisms. Int. Immunol. 16 (2004) 477-488
23. Murphy-Ullrich J.E. The de-adhesive activity of matricellular proteins: is intermediate cell adhesion an adaptive state?. J. Clin. Invest. 107 (2001) 785-790
24. Nau G.J., Liaw L., Chupp G.L., Berman J.S., Hogan B.L., and Young R.A. Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin. Infect. Immun. 67 (1999) 4223-4230
25. Naveau S., Giraud V., Borotto E., Aubert A., Capron F., and Chaput J.C. Excess weight risk factor for alcoholic liver disease. Hepatology 25 (1997) 108-111
26. Nomiyama T., Perez-Tilve D., Ogawa D., Gizard F., Zhao Y., Heywood E.B., Jones K.L., Kawamori R., Cassis L.A., Tschop M.H., and Bruemmer D. Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice. J. Clin. Invest. 117 (2007) 2877-2888
27. Okamura H., Tsutsi H., Komatsu T., Yutsudo M., Hakura A., Tanimoto T., Torigoe K., Okura T., Nukada Y., Hattori K., et al. Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature 378 (1995) 88-91
28. Pelleymounter M.A., Cullen M.J., Baker M.B., Hecht R., Winters D., Boone T., and Collins F. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269 (1995) 540-543
29. Sage E.H. Regulation of interactions between cells and extracellular matrix: a command performance on several stages. J. Clin. Invest. 107 (2001) 781-783
30. Sahai A., Malladi P., Melin-Aldana H., Green R.M., and Whitington P.F. Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model. Am. J. Physiol. Gastrointest. Liver Physiol. 287 (2004) G264-273
31. Sahai A., Malladi P., Pan X., Paul R., Melin-Aldana H., Green R.M., and Whitington P.F. Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin. Am. J. Physiol. Gastrointest. Liver Physiol. 287 (2004) G1035-1043
32. Sun J., Xu Y., Dai Z., and Sun Y. Intermittent high glucose enhances proliferation of vascular smooth muscle cells by upregulating osteopontin. Mol. Cell Endocrinol. 313 (2009) 64-69
33. Tanaka Y., Takahashi A., Watanabe K., Takayama K., Yahata T., Habu S., and Nishimura T. A pivotal role of IL-12 in Th1-dependent mouse liver injury. Int. Immunol. 8 (1996) 569-576
34. Wang Y., Mochida S., Kawashima R., Inao M., Matsui A., YouLuTu Z.Y., Nagoshi S., Uede T., and Fujiwara K. Increased expression of osteopontin in activated Kupffer cells and hepatic macrophages during macrophage migration in Propionibacterium acnes-treated rat liver. J. Gastroenterol. 35 (2000) 696-701
35. Yang S.Q., Lin H.Z., Lane M.D., Clemens M., and Diehl A.M. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 2557-2562