Synthesis of new 2(1H)-quinoxalinone derivatives for antimicrobial and antiinflammatory evaluation

Medicinal Chemistry Research

Volumn 18, Issue 9, 2009, Pages 782-797

  El Sabbagh, Osama I ^a   El Sadek, Mohamed E ^a   Lashine, Sayed M ^a   Yassin, Shada H ^b   El Nabtity, Sameh M ^a  

^a Zagazig University   (Egypt)

^b SANA A UNIVERSITY   (Yemen)

Author keywords

2(1H) Quinoxalinones; Antiinflammatory activity; Antimicrobial activity; Synthesis

Indexed keywords

3 [(2 PHENYLHYDRAZONO)METHYL] 4A,5,6,7,8,8A HEXAHYDRO 2(1H) QUINOXALINONE; 3 [(4 AMINO 5 MERCAPTO 4H 1,2,4 TRIAZOL 3 YL)METHYL] 2(1H) QUINOXALINONE; 3 [(5 MERCAPTO 1,3,4 OXADIAZOL 2 YL)METHYL] 2(1H) QUINOXALINONE; 3 [(5 MERCAPTO 4 ALLYL 4H 1,2,4 TRIAZOL 3 YL)METHYL] 2(1H) QUINOXALINONE; 3 [(5 MERCAPTO 4 ETHYL 4H 1,2,4 TRIAZOL 3 YL)METHYL] 2(1H) QUINOXALINONE; 3 [(5 MERCAPTO 4 PHENYL 4H 1,2,4 TRIAZOL 3 YL)METHYL] 2(1H) QUINOXALINONE; 3 [[2 (4 BROMOPHENYL)HYDRAZONO]METHYL] 4A,5,6,7,8,8A HEXAHYDRO 2(1H) QUINOXALINONE; 3 [[2 (4 CHLOROPHENYL)HYDRAZONO]METHYL] 4A,5,6,7,8,8A HEXAHYDRO 2(1H) QUINOXALINONE; 3 [[2 (4 FLUOROPHENYL)HYDRAZONO]METHYL] 4A,5,6,7,8,8A HEXAHYDRO 2(1H) QUINOXALINONE; 3 [[2 (4 METHYLPHENYL)HYDRAZONO]METHYL] 4A,5,6,7,8,8A HEXAHYDRO 2(1H) QUINOXALINONE; 3 [N (4 CHLOROPHENYL 2 THIOXO 2,3 DIHYDROTHIAZOL 3 YL)AMINOCARBONYLMETHYL] 2(1H)QUINOXALINONE; 3 [N (4 METHYLPHENYL 2 THIOXO 2,3 DIHYDROTHIAZOL 3 YL)AMINOCARBONYLMETHYL] 2(1H)QUINOXALINONE; 3 [N (4 PHENYL 2 THIOXO 2,3 DIHYDROTHIAZOL 3 YL)AMINOCARBONYL METHYL] 2(1H)QUINOXALINONE; 3 [N (PHTHALIMIDO)AMINOCARBONYLMETHYL)] 4A,5,6,7,8,8A HEXAHYDRO 2(1H) QUINOXALINONE; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; CELECOXIB; CIPROFLOXACIN; INDOMETACIN; N 1 [(2 OXO 1,2 DIHYDROQUINOXALIN 3 YL)METHYLCARBONYL] N 4 ALLYL THIOSEMICARBAZIDE; N 1 [(2 OXO 1,2 DIHYDROQUINOXALIN 3 YL)METHYLCARBONYL] N 4 ETHYL THIOSEMICARBAZIDE; N 1 [(2 OXO 1,2 DIHYDROQUINOXALIN 3 YL)METHYLCARBONYL] N 4 PHENYL THIOSEMICARBAZIDE; N 1 [(2 OXO 1,2,4A,5,6,7,8,8A OCTAHYDROQUINOXALIN 3 YL)METHYLCARBONYL] N 4 ALLYLTHIOSEMICARBAZIDE; N 1 [(2 OXO 1,2,4A,5,6,7,8,8A OCTAHYDROQUINOXALIN 3 YL)METHYLCARBONYL] N 4 ETHYLTHIOSEMICARBAZIDE; N 1 [(2 OXO 1,2,4A,5,6,7,8,8A OCTAHYDROQUINOXALIN 3 YL)METHYLCARBONYL] N 4 PHENYLTHIOSEMICARBAZIDE; NYSTATIN; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; FEMALE; MALE; NONHUMAN; PAW EDEMA; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STAPHYLOCOCCUS AUREUS; ULCEROGENESIS;

EID: 73449088756     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-009-9203-y     Document Type: Article

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