In vitro and in vivo anti-tumoral activities of imidazo[1,2-a]quinoxaline, imidazo[1,5-a]quinoxaline, and pyrazolo[1,5-a]quinoxaline derivatives

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 13, 2008, Pages 6601-6610

  Moarbess, Georges ^a   Deleuze Masquefa, Carine ^a   Bonnard, Vanessa ^a   Gayraud Paniagua, Stéphanie ^a   Vidal, Jean Rémi ^c   Bressolle, Françoise ^b,c   Pinguet, Frédéric ^c   Bonnet, Pierre Antoine ^a  

^a Laboratoire de Pharmacochimie   (France)

^b UNIV MONTPELLIER   (France)

^c CENTRE VAL D AURELLE   (France)

Author keywords

Imidazoquinoxalines; Imiquimod; In vitro activity; Melanoma; Pharmacodynamic evaluation; Pyrazoloquinoxaline

Indexed keywords

2 CHLORO 1 ISOBUTYL 6 METHYLPHENYL N METHYLIMIDAZO[1,2 A]QUINOXALIN 4 AMINE; 2 CHLORO 6 METHYLPHENYL N METHYL 1 PHENETHYLIMIDAZO[1,2 A]QUINOXALIN 4 AMINE; 3 ISOBUTYL N METHYLPYRAZOLO[1,5 A]QUINOXALIN 4 AMINE; 3 ISOBUTYL N,N DIMETHYLPYRAZOLO[1,5 A]QUINOXALIN 4 AMINE; DOXORUBICIN; EAPB 0103; EAPB 0104; EAPB 0105; EAPB 0201; EAPB 0202; EAPB 0203; EAPB 0204; EAPB 0205; EAPB 0206; FOTEMUSTINE; IMIDAZO[1,2 A]QUINOXALINE DERIVATIVE; IMIDAZO[1,5 A]QUINOXALINE DERIVATIVE; IMIQUIMOD; IRINOTECAN; METHOTREXATE; N METHYL 1 METHYLIMIDAZO[1,5 A]QUINOXALIN 4 AMINE; N METHYL 1 PHENYLIMIDAZO[1,5 A]QUINOXALIN 4 AMINE; N METHYLIMIDAZO[1,5 A]QUINOXALIN 4 AMINE; N,N DIMETHYLIMIDAZO[1,5 A]QUINOXALIN 4 AMINE; PYRAZOLO[1,5 A]QUINOXALINE DERIVATIVE; QUINOXALINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; LYMPHOMA CELL LINE; MELANOMA CELL; MOUSE; NONHUMAN; PHARMACODYNAMICS;

MUS;

EID: 44949100201     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.05.022     Document Type: Article

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