A model of cardiovascular disease giving a plausible mechanism for the effect of fractionated low-dose ionizing radiation exposure

PLoS Computational Biology

Volumn 5, Issue 10, 2009, Pages

  Little, Mark P ^a   Gola, Anna ^a   Tzoulaki, Ioanna ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLOGY; DISEASES; DOSIMETRY; RADIATION EFFECTS; RISK ASSESSMENT; UNCERTAINTY ANALYSIS;

CARDIOVASCULAR DISEASE; CAUSES OF DEATH; CORONARY HEART DISEASE; FRACTIONATED RADIATION; LOW DOSE; LOW RADIATION; PLAUSIBLE MECHANISMS; RADIATION EXPOSURE; REACTION-DIFFUSION MODELS; SPATIAL REACTION;

IONIZING RADIATION;

LOW DENSITY LIPOPROTEIN CHOLESTEROL; MONOCYTE CHEMOTACTIC PROTEIN 1; CCL2 PROTEIN, HUMAN;

ARTICLE; ATHEROSCLEROSIS; ATOMIC BOMB SURVIVOR; CANCER MORTALITY; CARDIOVASCULAR DISEASE; CELL DEATH; CHRONIC INFLAMMATION; DIFFUSION; DOSE RESPONSE; HUMAN; HYPOTHESIS; IONIZING RADIATION; JAPANESE; MATHEMATICAL MODEL; MONOCYTE; OCCUPATIONAL EXPOSURE; PREDICTION; PROTEIN DEGRADATION; RADIATION DOSE FRACTIONATION; RADIATION EXPOSURE; RADIATION HAZARD; RADIATION PROTECTION; REACTION ANALYSIS; UNCERTAINTY; ALGORITHM; BIOLOGICAL MODEL; ENDOTHELIUM CELL; METABOLISM; RADIATION INJURY; RADIATION RESPONSE; STATISTICAL MODEL; TIME;

ALGORITHMS; ATHEROSCLEROSIS; CHEMOKINE CCL2; CHOLESTEROL, LDL; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENDOTHELIAL CELLS; HUMANS; LINEAR MODELS; MODELS, CARDIOVASCULAR; MONOCYTES; OCCUPATIONAL EXPOSURE; RADIATION INJURIES; RADIATION, IONIZING; TIME FACTORS;

EID: 73449086055     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000539     Document Type: Article

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