Radiation and mortality of workers at Oak Ridge National Laboratory: Positive associations for doses received at older ages

Environmental Health Perspectives

Volumn 107, Issue 8, 1999, Pages 649-656

  Richardson, David B ^a   Wing, Steve ^a  

^a IL   (United States)

Author keywords

Epidemiology; Ionizing radiation; Oak Ridge National Laboratory

Indexed keywords

ADULT; AGED; ARTICLE; CANCER MORTALITY; CANCER STATISTICS; FEMALE; HUMAN; IONIZING RADIATION; LABORATORY; LOW ENERGY RADIATION; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; PRIORITY JOURNAL; RADIATION CARCINOGENESIS; RADIATION DOSE; RADIATION EXPOSURE; UNITED STATES;

QUERCUS;

EID: 0032877235     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.99107649     Document Type: Article

References (62)

1. Cardis E, Gilbert ES. Carpenter U Howe G, Kalo l. Lave EC. Armstrong BK, Beral V, Cowper G, Douglas A, et al. Direct estimates of cancer mortality due to low doses of ionising radiation: an international study. Lancet 344:1039-1043(1994).
2. National Research Council, Committee on the Biological Effects of Ionizing Radiation. Health effects of exposure to low levels of ionizing radiation (BEIR V). Washington, DC:National Academy Press, 1990.
3. United Nations Scientific Committee on the Effects of Atomic Radiation. Sources and Effects of Ionizing Radiation. NewYork:United Nations, 1993.
4. International Commission on Radiological Protection. 1990 Recommendations of the International Commission on Radiological Protection, Vol 21 (Smith H, ed). Ist ed. Oxford:Pergamon Press, 1991.
5. Wing S, West CM, Wood JL Tankersley W. Recording of external radiation exposures at Oak Ridge National Laboratory: implications for epidemiological studies. J Expo Anal Environ Epidemiol 4:83-93 (1994).
6. Watkins J, Cragle D, Frame E, Reagan J, West C, CrawfordBrown D, Tankersley W. Collection, validation, and treatment of data for a mortality study of nuclear industry workers. Appl Occup Environ Hyg 12:195-205 (1997).
7. Checkoway H, Mathew RM, Shy CM, Watson JE Jr, Tankersley WG, Wolf SH, Smith JC, Fry SA. Radiation, work experience, and cause specific mortality among workers at an energy research laboratory. Br J Ind Med 42:525-533 (1985).
8. Wing S, Shy CM, Wood JL, Wolf S, Cragle OL, Frome EL Mortality among workers at Oak Ridge National Laboratory. Evidence of radiation effects in follow-up through 1984. JAMA 265:1397-1402(1991).
9. Wing S, Shy CM, Wood JL, Wolf S, Cragle DL Tankersley W, Frome EL Job factors, radiation and cancer mortality at Oak Ridge National Laboratory: follow-up through 1984. Am J Ind Med 23:265-279 (1993).
10. Richardson DB, Wing S. Greater sensitivity to radiation exposures at older ages among workers at Oak Ridge National Laboratory: follow-up through 1990. Int J Epidemiol (in press).
11. Richardson D, Wing S. Methods for investigating age differences in the effects of prolonged exposures. Am J Ind Med 33:123-130 (1998).
12. Frome EL, Cragle DL, Watkins JP, Wing S, Shy CM, Tankersley WG, West CM. A mortality study of employees of the nuclear industry in Oak Ridge. Tennessee. Radiât Res 148:64-80 (1997).
13. Ron E, Carter R, Jablon S, Mabuchi K. Agreement between death certificate and autopsy diagnoses among atomic bomb survivors. Epidemiology 5:48-56 (1994).
14. Siemiatycki J, Krewski D, Franco E, Kaiserman M. Associations between cigarette smoking and each of 21 types of cancer: a multi-site case-control study. Int J Epidemiol 24:504-514 (1995).
15. Watson JE, Wood JL, Tankersley WG, West CM. Estimation of radiation doses for workers without monitoring data for retrospective epidemiologic studies. Health Phys 67:402-405 (1994).
16. Preston DL, Lubin JH, Pierce DA, McConney ME. Epicure: User's Guide. Seattle, WA:Hirosoft International Corporation, 1993.
17. Breslow NE. Day NE. Statistical Methods in Cancer Research: The Design and Analysis of Cohort Studies, Vol II. Lyon:lnternational Agency for Research on Cancer, 1987.
18. Wood JW, Richardson DB, Wing S. A simple program to create exact person-time data in cohort analyses. Int J Epidemiol 26:395-399 (1997).
19. Arrighi HM, Hertz-Picciotto I. The evolving concept of the healthy worker survivor effect. Epidemiology 5:189-196(1994).
20. Steenland K, Stayner L The importance of employment status in occupational cohort mortality studies. Epidemiology 2:418-423 (1991).
21. Steenland K. Deddens J. Salvan A, Stayner L Negative bias in exposure-response trends in occupational studies: modeling the healthy workers survivor effect Am J Epidemiol 143:202-210 (19961.
22. Allison PD. Event History Analysis: Regression for Longitudinal Event Data. Quantitative Applications in the Social Sciences, Series 07-046 (Lewis-Beck MS, ed). Newbury Park, CA:Sage Publications, 1984.
23. Gilbert ES, Cragle DL Wiggs LD. Updated analyses of combined mortality data for workers at the Hanford Site, Oak Ridge National Laboratory, and Rocky Flats Weapons Plant. Radiât Res 136:408-421 (1993).
24. Richardson D, Wing S. Final Report Time-Related Factors in Radiation-Cancer Dose Response. R03 OH03343. Cincinnati, OH:National Institute for Occupational Safety and Health, 1997.
25. Wilkinson GS. Epidemiologie studies of nuclear and radiation workers: an overview of what is known about health risks posed by the nuclear industry. Occtip Med 6:715-724(1991).
26. Cardis E, Gilbert ES, Carpenter L, Howe G, Kato I, Fix J, Salmon L, Cowper G, Armstrong BK, Beral V, et al. Combined Analyses of Cancer Mortality Among Nuclear Industry Workers in Canada, the United Kingdom and the United States of America. IARC Technical Rpt No 25. Lyon:lnternational Agency for Research on Cancer, 1995.
27. Gilbert ES. Mortality of workers at the Oak Ridge National Laboratory. Health Phys 62:260-264 (1992).
28. Wing S, Shy CM, Wood JL, Wolf S, Cragle DL, Frome EL Mortality of workers at the Oak Ridge National Laboratory-Reply. Health Phys 62:261-264 (1992).
29. Steenland K, Beaumont J, Halperin W. Methods of control for smoking in occupational cohort mortality studies. Scand J Work Environ Health 10:143-149 (1984).
30. Axelson 0. Confounding from smoking in occupational epidemiology. Br J Ind Med 46:505-507 (1989).
31. Petersen GR, Gilbert ES, Buchanan JA, Stevens RG. A case-cohort study of lung cancer, ionizing radiation, and tobacco smoking among males at the Hanford Site. Health Phys 58:3-11 (1990).
32. Siemiatycki J, Wacholder S, Dewar R, Cardis E, Greenwood C, Richardson L Degree of confounding bias related to smoking, ethnic group, and socioeconomic status in estimates of the associations between occupation and cancer. J Occup Med 30:617-625 (1988).
33. Siemiatycki J, Wacholder S, Dewar R, Wald L, Begin D, Richardson L, Rosenman K, Gerin M. Smoking and degree of occupational exposure: are internal analyses in cohort studies likely to be confounded by smoking status? Am J Ind Med 13:59-69 (1988).
34. Axelson 0, Steenland K. Indirect methods of assessing the effects of tobacco use in occupational studies. Am J Ind Med 13:105-118(1988).
35. Kerr GD. Missing dose from mortality studies of radiation effects among workers at Oak Ridge National Laboratory. Health Phys 66:206-208 (1994).
36. Mitchell TJ, Ostrouchov G. Frame EL, Kerr GO. A method for estimating occupational radiation dose to individuals, using weekly dosimetry data. ORNL-6778. Springfield, VA:National Technical Information Services, 1993.
37. Tankersley WG, West CM, Watson JE, Reagan JL. Retrospective assessment of radiation exposures at or below the minimum detectable level at a federal nuclear reactor facility. Appl Occup Environ Hyg 11:330-333(1996).
38. Crump KS, Alien BC, Howe RB, Crockett PW. Time-related factors in quantitative risk assessment. J Chronic Dis 40(suppl2):101S-111S|1987).
39. Cohen HJ. Biology of aging as related to cancer. Cancer 74:2092-2100(1994).
40. Ershler WB. The influence of an aging immune system on cancer incidence and progression. J Gerontol 48:B3-7 (1993).
41. Fabrikant Jl. Factors that modify risks of radiationinduced cancer. Health Phys 59:77-87 (1990).
42. Narayanan S. Laboratory markers as an index of aging. Ann Clin Lab Sci 26:50-59 (1996).
43. Charlton BG. Senescence, cancer and 'endogenous parasites': a salutogenic hypothesis. J R Coll Physicians Lond 30:10-12 (1996).
44. Jan/holm B. Dose-response in epidemiology-age and time aspects. Am J Ind Med 21:101-106 (1992).
45. Stewart AM, Kneale GW. Relations between age at occupational exposure to ionising radiation and cancer risk. Occup Environ Med 53:225-230 (1996).
46. Pearce N, Checkoway H, Shy C. Time-related factors as potential confounders and effect modifiers in studies based on an occupational cohort. Scand J Work Environ Health 12:97-107 (1986).
47. Thompson DE, Mabuchi K, Ron E, Soda M, Tokunaga M, Ochikubo S, Sugimoto S, Ikeda T, Terasaki M, Izumi S, et al. Cancer incidence in atomic bomb survivors. Part II: Solid tumors, 1958-1987. Radiât Res 137(2 suppl):S17-S67 (1994).
48. Preston DL. Kusumi S, Tomonaga M, Izumi S, Ron E, Kuramoto A, Kamada N, Dohy H, Matsui T, Nonaka H, et al. Cancer incidence in atomic bomb survivors. 3. Leukemia, lymphoma and multiple myeloma, 1950-1987. Radiât Res 137(2 suppl):S68-S97 (1994).
49. Boice JD Jr, Preston D, Davis FG, Monson RR. Frequent chest X-ray fluoroscopy and breast cancer incidence among tuberculosis patients in Massachusetts. Radiât Res 125:214-222 (1991).
50. Stewart AM, Kneale GW. A-bomb radiation and evidence of late effects other than cancer. Health Phys 58:729-735(19901.
51. Stewart AM, Kneale GW. A-bomb survivors: further evidence of late effects of early deaths. Health Phys 64:467-472(1993).
52. Stewart AM, Kneale GW. Late effects of A-bomb radiation-risk problems unrelated to the new dosimetry [letter]. Health Phys 54:567-569 (1988).
53. Kneale GW, Stewart AM. Factors affecting recognition of cancer risks of nuclear workers. Occup Environ Med 52:515-523(1995).
54. Dupree EA, Watkins JP, Ingle JN, Wallace PW, West CM, Tankersley WG. Uranium dust exposure and lung cancer risk in four uranium processing operations. Epidemiology 6:370-375 (1995).
55. Geiger HJ, Rush D, Michaels D. Dead Reckoning: A Critical Review of the Department of Energy's Epidemiologie Research. Washington, DC:Physicians for Social Responsibility, 1992.
56. U.S. DOE, Office of Epidemiology and Health Surveillance. Comprehensive Epidemiologie Data Resource (CEDR). Washington, DC:U.S. Department of Energy, 1993.
57. Stockwell HG, Brooks BG, Holmes HH, Durst MJ, Shim YK, Heinig PE. The Department of Energy's Comprehensive Epidemiologie Data Resource: a publicuse database on radiation exposure. Am J Public Health 86:747-748 (1995).
58. Brown P. Popular epidemiology revisited. Curr Sociol 45:137-156 (1997).
59. Rose G. Environmental health: problems and prospects. J R Coll Physicians Lond 25:43-52 (1991).
60. Fix JJ, Salmon L, Cowper G, Cardis E. A retrospective evaluation of the dosimetry employed in an international combined epidemiological study. Radial Prot Dosimetry 74:39-53(1997).
61. Tornqvist L, Vartia P, Varia YO. How should relative changes be measured? Am Stat 39:43-46 (1985).
62. National Research Council, Committee on the Biological Effects of Ionizing Radiation (BEIR IV). Health Risks of Radon and Other Internally Deposited Alpha-Emitters. Washington, DC:National Academy Press, 1988.