An in vitro coculture model of transmigrant monocytes and foam cell formation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 19, Issue 10, 1999, Pages 2330-2339

  Takaku, Mikio ^a,e   Wada, Youichiro ^a,d   Jinnouchi, Katsunori ^b   Takeya, Motohiro ^b   Takahashi, Kiyoshi ^b   Usuda, Hiroyuki ^c   Naito, Makoto ^c   Kurihara, Hiroki ^d   Yazaki, Yoshio ^d   Kumazawa, Yoko ^a   Okimoto, Yuko ^a   Umetani, Michihisa ^a   Noguchi, Noriko ^a   Niki, Etsuo ^a   Hamakubo, Takao ^a   Kodama, Tatsuhiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^c NIIGATA UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Atherosclerosis; Chemoattractants; Foam cells; Macrophages; Oxidized LDLs

Indexed keywords

CD14 ANTIGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 4; FAT DROPLET; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MATRIX PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; SCAVENGER RECEPTOR;

ANIMAL CELL; AORTA MEDIA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL TRANSFORMATION; CELL ULTRASTRUCTURE; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; FOAM CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LEUKOCYTE MIGRATION; MACROPHAGE; MONOCYTE; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RABBIT; SMOOTH MUSCLE FIBER;

EID: 0032831802     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.19.10.2330     Document Type: Article

References (46)

1. Gerrity RG. The role of the monocyte in atherogenesis, I: transition of blood-borne monocytes into foam cells in fatty lesions. Am J Pathol. 1981;103:181-190.
2. Gerrity RG. The role of the monocyte in atherogenesis, II: migration of foam cells from atherosclerotic lesions. Am J Pathol. 1981;103:191-200.
3. Ross R. The pathogenesis of atherosclerosis: an update. N Engl J Med. 1986;314:488-500.
4. Ross R. Cell biology of atherosclerosis. Annu Rev Physiol. 1995;57: 791-804.
5. Furie MB, Cramer EB, Naprstek BL, Silverstein SC. Cultured endothelial cell monolayers that restrict the transendothelial passage of macromolecules and electrical current. J Cell Biol. 1984;98:1033-1041.
6. Navab M, Hough GP, Stevenson LW, Drinkwater DC, Laks H, Fogelman AM. Monocyte migration into the subendothelial space of a coculture of adult human aortic endothelial and smooth muscle cells. J Clin Invest. 1988;82:1853-1863.
7. Navab M, Liao F, Hough GP, Ross LA, Van Lenten BJ, Rajavashisth TB, Lusis AJ, Laks H, Drinkwater DC, Fogelman AM. Interaction of monocytes with cocultures of human aortic wall cells involves interleukins 1 and 6 with marked increases in connexin43 message. J Clin Invest. 1991;87:1763-1772.
8. Watson AD, Berliner JA, Hama SY, La Du BN, Faull KF, Fogelman AM, Navab M. Protective effect of high density lipoprotein associated paraoxonase: inhibition of the biological activity of minimally oxidized low density lipoprotein. J Clin Invest. 1995;96:2882-2891.
9. Ishikawa K, Navab M, Leitinger N, Fogelman AM, Lusis AJ. Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL. J Clin Invest. 1997;100:1209-1216.
10. Van Lenten BJ, Hama SY, de Beer FC, Stafforini DM, McIntyre TM, Prescott SM, La Du BN, Fogelman AM, Navab M. Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response: loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures. J Clin Invest. 1995;96:2758-2767.
11. Navab M, Hama SY, Van Lenten BJ, Drinkwater DC, Laks H, Fogelman AM. A new antiinflammatory compound, leumedin, inhibits modification of low density lipoprotein and the resulting monocyte transmigration into the subendothelial space of cocultures of human aortic wall cells. J Clin Invest. 1993;91:1225-1230.
12. Folkman J, Haudenschild CC, Zetter BR. Long-term culture of capillary endothelial cells. Proc Natl Acad Sci USA. 1979;76:5217-5221.
13. Madri JA, Pratt BM, Tucker AM. Phenotypic modulation of endothelial cells by transforming growth factor-β depends upon the composition and organization of the extracellular matrix. J Cell Biol. 1988;106: 1375-1384.
14. Guyton JR, Klemp KF. Early extracellular and cellular lipid deposits in aorta of cholesterol-fed rabbits. Am J Pathol. 1992;141:925-936.
15. Frank JS, Fogelman AM. Ultrastructure of the intima in WHHL and cholesterol-fed rabbit aortas prepared by ultra-rapid freezing and freeze-etching. J Lipd Res. 1989;30:967-978.
16. Watanabe Y. Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit). Atherosclerosis. 1980;36:261-268.
17. Kita T, Nagano Y, Yokode M, Ishii K, Kume N, Ooshima A, Yoshida H, Kawai C. Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia. Proc Natl Acad Sci USA. 1987;84:5928-5931.
18. Cybulsky MI, Gimbrone MA Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 1991;251: 788-791.
19. Sandig M, Negrou E, Rogers KA. Changes in the distribution of LFA-1, catenins, and F-actin during transendothelial migration of monocytes in culture. J Cell Sci. 1997;110(pt 22):2807-2818.
20. Takahashi M, Ikeda U, Masuyama J, Kitagawa S, Kasahara T, Saito M, Kano S, Shimada K. Involvement of adhesion molecules in human monocyte adhesion to and transmigration through endothelial cells in vitro. Atherosclerosis. 1994;108:73-81.
21. Goldstein JL, Basu SK, Brown MS. Receptor-mediated endocytosis of low-density lipoprotein in cultured cells. Methods Enzymol. 1983;98: 241-260.
22. Cynshi O, Takashima Y, Suzuki T, Kawabe Y, Ohba Y, Kodama T. Characterization of aggregated low density lipoproteins induced by copper-catalyzed oxidation. J Atheroscler Thromb. 1994;1:87-97.
23. Kodama T, Reddy P, Kishimoto C, Krieger M. Purification and characterization of a bovine acetyl low density lipoprotein receptor. Proc Natl Acad Sci USA. 1988;85:9238-9242.
24. Ross R, Klebanoff SJ. The smooth muscle cell, I: in vivo synthesis of connective tissue proteins. J Cell Biol. 1971;50:159-171.
25. Ross R. The smooth muscle cell, II: growth of smooth muscle in culture and formation of elastic fibers. J Cell Biol. 1971;50:172-186.
26. Hoogewerf AJ, Kuschert GSV, Proudfoot AEI, Porlat F, Clark-Lewis I, Power CA, Wells TNC. Glycosaminoglycans mediate cell surface oligomerization of chemokines. Biochemistry. 1997;36:13570-13578.
27. Nagafuchi A, Tsukita SH. The nervous tissue-specific loss of the expression of α-catenin, the 102kD cadherin-associated protein, during development. Dev Growth Differ. 1994;36:59-71.
28. Osawa M, Masuda M, Harada N, Lopes RB, Fujiwara K. Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells. Eur J Cell Biol. 1997;72:229-237.
29. Ayalon O, Sabanai H, Lampugnani MG, Dejana E, Geiger B. Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells. J Cell Biol. 1994;126:247-258.
30. Welgus HG, Campbell EJ, Curry JD, Eisen AZ, Senior RM, Wilhelm SM, Goldberg GI. Neural metalloproteinase produced by human mononuclear phagocytes: enzyme profile, regulation, and expression during cellular development. J Clin Invest. 1990;86:1496-1502.
31. Honda M, Akiyama H, Yamada Y, Kondo H, Kawabe Y, Takeya M, Takahashi K, Suzuki H, Doi T, Sakamoto A, Ookawara S, Mato M, Gough PJ, Greaves DR, Gordon S, Kodama T, Matsushita M. Immunohistochemical evidence for a macrophage scavenger receptor in Mato cells and reactive microglia of ischemia and Alzheimer's disease. Biochem Biophys Res Commun. 1998;245:734-740.
32. Pulford KAF, Rigney EM, Micklem KJ. KP1: a new monoclonal antibody that directs a monocyte/macrophage associated antigen in routinely processed tissue sections. J Clin Pathol. 1989;42:414-421.
33. Zeng L, Takeya M, Takahashi K. AM-3K, a novel monoclonal antibody specific for tissue macrophages and its application to pathological investigation. J Pathol. 1996;178:207-214.
34. Madri JA, Dreyer B, Pitlick FA, Furthmayr H. The collagenous components of the subendothelium: correlation of structure and function. Lab Invest. 1980;43:303-315.
35. Sado Y, Kagawa M, Naito I, Ueki Y, Seki T, Momota R, Oohashi T, Ninomiya Y. Organization and expression of basement membrane collagen IV genes and their roles in human disorders. J Biochem (Tokyo). 1998;123:767-776.
36. Baldus SE, Wickenhauser C, Stefanovic A, Schmitz B, Thiele J, Fischer R. Enrichment of human bone marrow mononuclear phagocytes and characterization of macrophage subpopulations by immunoenzymatic double staining. Histochem J. 1998;30:285-291.
37. Sleasman JW, Leon BH, Aleixo LF, Rojas M, Goodenow MM. Immunomagnetic selection of purified monocyte and lymphocyte populations from peripheral blood mononuclear cells following cryopreservation. Clin Diagn Lab Immunol. 1997;4:653-658.
38. Akagawa KS, Takasuka N, Nozaki Y, Komuro I, Azuma M, Ueda M, Naito M, Takahashi K. Generation of CD1+RelB+ dendritic cells and tartrate-resistant acid phosphatase-positive osteoclast-like multinucleated giant cells from human monocytes. Blood. 1996;88:4029-4039.
39. Yoshimura T, Yuhki N. Neutrophil attractant/activation protein-1 and monocyte chemoattractant protein-1 in rabbit: cDNA cloning and their expression in spleen cells. J Immunol. 1991;146:3483-3488.
40. Yoshimura T, Takeya M, Takahashi K, Kuratsu J, Leonard EJ. Production and characterization of mouse monoclonal antibodies against human monocyte chemoattractant protein-1. J Immunol. 1991;147:2229-2233.
41. Yla-Herttuala S, Lipton BA, Rosenfeld ME, Sarkioja T, Yoshimura T, Leonard EJ, Witztum JL, Steinberg D. Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc Natl Acad Sci USA. 1991;88: 5252-5256.
42. Meredith JJ, Fazeli B, Schwarz MA. The extracellular matrix as a cell survival factor. Mol Biol Cell. 1993;4:953-961.
43. Wesley RB, Meng X, Godin D, Galis ZS. Extracellular matrix modurates macrophage functions characteristic to atheroma. Arterioscler Thromb Vasc Biol. 1998;18:432-440.
44. Naito M, Suzuki H, Mori T, Matsumoto A, Kodama T, Takahashi K. Coexpression of type I and type II human macrophage scavenger receptors in macrophages of various organs and foam cells in atherosclerotic lesions. Am J Pathol. 1992;141:591-599.
45. Chao FF, Amende LM, Blanchette-Mackie EJ, Skarlatos SI, Gamble W, Resau JH, Mergner WT, Kruth HS. Unesterified cholesterol-rich lipid particles in atherosclerotic lesions of human and rabbit aortas. Am J Pathol. 1988;131:73-83.
46. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801-980.