Down-regulation of lipocalin 2 expression in mouse testis after exposure to electromagnetic field

Iranian Journal of Medical Sciences

Volumn 34, Issue 4, 2009, Pages 265-270

  Roushandeh, Amaneh Mohammadi ^a   Halabian, Raheleh ^b   Mozafari, Parisa ^b   Rad, Jafar Soleimani ^a   Sadeghzadeh Oskouei, Behnaz ^a   Kuchaksaraei, Ali Samadi ^c   Roudkenar, Mehryar Habibi ^b  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b IRANIAN BLOOD TRANSFUSION ORGANIZATION   (Iran)

^c IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Electromagnetic fields; Fertility; Lcn2; Reactive oxygen species; Testis

Indexed keywords

MESSENGER RNA; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; DOWN REGULATION; ELECTROMAGNETIC FIELD; GENE EXPRESSION; HISTOLOGY; LEYDIG CELL; MALE; MICROSCOPY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPERMATOCYTE; TESTIS; WESTERN BLOTTING;

EID: 73349137652     PISSN: 02530716     EISSN: 17353688     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Khaki AA, Tubbs RS, Shoja MM, et al. The effects of an electromagnetic field on the boundary tissue of the seminiferous tubules of the rat: A light and transmission electron microscope study. Folia Morphol (Warsz) 2006; 65, 188-94.
2. Ozguner M, Koyu A, Cesur G, et al. Biological and morphological effects on the reproductive organ of rats after exposure to electromagnetic field. Saudi Med J 2005; 26: 405-10
3. Lee JS, Ahn SS, Jung KC, et al. Effects of 60 Hz electromagnetic field exposure on testicular germ cell apoptosis in mice. Asian J Androl 2004; 6: 29-34.
4. Kovacic P, Cooksy AL. Unifying mechanism for toxicity and addiction by abused drugs: electron transfer and reactive oxygen species. Med Hypotheses 2005; 64: 357-66.
5. Lantow M, Lupke M, Frahm J, et al. ROS release and Hsp70 expression after exposure to 1,800 MHz radiofrequency electromagnetic fields in primary human monocytes and lymphocytes. Radiat Environ Biophys 2006; 45: 55-62.
6. Yao K, Wu W, Yu Y, et al. Effect of superposed electromagnetic noise on DNA damage of lens epithelial cells induced by microwave radiation. Invest Ophthalmol Vis Sci 2008; 49: 2009-15.
7. Svedenstål BM, Johanson KJ, Mattsson MO, Paulsson LE. DNA damage, cell kinetics and ODC activities studied in CBA mice exposed to electromagnetic fields generated by transmission lines. In Vivo 1999; 13: 507-13.
8. Di Pietro A, Visalli G, Munaò F, et al. Oxidative damage in human epithelial alveolar cells exposed in vitro to oil fly ash transition metals. Int J Hyg Environ Health 2009; 212: 196-208.
9. Roudkenar MH, Halabian R, Oodi A, et al. Upregulation of neutrophil gelatinaseassociated lipocalin, NGAL/Lcn2, in betathalassemia patients. Arch Med Res 2008; 39: 402-7.
10. Mishra J, Ma Q, Prada A, et al. Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J Am Soc Nephrol 2003; 14: 2534-43.
11. Kai MS, Kiyoshi M, Jau YL, Avtandil K. Dual Action of Neutrophil Gelatinase-Associated Lipocalin. J Am Soc Nephrol 2007; 18: 407-13.
12. Schmidt-Ott KM, Mori K, Li JY, et al. Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 2004; 432: 917-21.
13. Kuwabara T, Mori K, Mukoyama M, et al. Urinary neutrophil gelatinase-associated lipocalin levels reflect damage to glomeruli, proximal tubules, and distal nephrons. Kidney Int 2009 75: 285-94.
14. Mishra J, Dent C, Tarabishi R, et al. Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 2005; 365:1231-8.
15. Elangovan N, Lee YC, Tzeng WF, Chu ST. Delivery of ferric ion to mouse spermatozoa is mediated by lipocalin internalization. Biochem Biophys Res Commun 2004; 319: 1096-104.
16. Fujino RS, Tanaka K, Morimatsu M, et al. Spermatogonial cell-mediated activation of an IkappaBzeta-independent nuclear factorkappaB pathway in Sertoli cells induces transcription of the lipocalin-2 gene. Molecular Endocrinol 2006; 20: 904-15.
17. Devireddy LR, Teodoro JG, Richard FA, Green MR. Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation. Science 2001; 293: 829-34.
18. Lee YC, Liao C Jr, Li PT, et al. Mouse lipocalin as an enhancer of spermatozoa motility. Mol Biol Rep 2003; 30: 165-72.
19. Das S, Chattopadhyay R, Jana SK, et al. Cut-off value of reactive oxygen species for predicting semen quality and fertilization outcome. Syst Biol Reprod Med 2008; 54: 47-54.
20. Jarow JP, Budin RE, Dym M, et al. Quantitative pathologic changes in the human testis after vasectomy. A controlled study. N Engl J Med 1985; 313: 1252-6.
21. Chung MK, Lee SJ, Kim YB, et al. Evaluation of spermatogenesis and fertility in F1 male rats after in utero and neonatal exposure to extremely low frequency electromagnetic fields. Asian J Androl 2005; 7: 189-94.
22. Tong Z, Wu X, Ovcharenko D, et al. Neutrophil gelatinase-associated lipocalin as a survival factor. Biochem J 2005; 391: 441-8.
23. Roudkenar MH, Halabian R, Ghasemipour Z, et al. Neutrophil gelatinase-associated lipocalin acts as a protective factor against H(2)O(2) toxicity. Arch Med Res 2008; 39: 560-6.
24. Deepinder F, Cocuzza M, Agarwal A. Should seminal oxidative stress measurement be offered routinely to men presenting for infertility evaluation? Endocr Pract 2008; 14: 484-91.
25. Roudkenar MH, Kuwahara Y, Baba T, et al. Oxidative stress induced lipocalin 2 gene expression: addressing its expression under the harmful conditions. J Radiat Res (Tokyo) 2007; 48: 39-44.