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Volumn 16, Issue 10, 2009, Pages 2795-2804

Significance of alpha-fetoprotein and des-γ-carboxy prothrombin in patients with hepatocellular carcinoma undergoing hepatectomy

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; DECARBOXYPROTHROMBIN; TUMOR MARKER; BIOLOGICAL MARKER; PROTEIN PRECURSOR; PROTHROMBIN;

EID: 73349113221     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-009-0618-y     Document Type: Article
Times cited : (100)

References (38)
  • 1
    • 28844480321 scopus 로고    scopus 로고
    • Practice Guidelines Committee American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma
    • Bruix J, Sherman M. Practice Guidelines Committee, American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma. Hepatology. 2005;42:1208-36.
    • (2005) Hepatology. , vol.42 , pp. 1208-36
    • Bruix, J.1    Sherman, M.2
  • 2
    • 73649210096 scopus 로고
    • Production of embryonal alpha-globulin by transplantable mouse hepatomas
    • Abelev GI, Perova SD, Khramkova NI, et al. Production of embryonal alpha-globulin by transplantable mouse hepatomas. Transplantation. 1963;1:174-80
    • (1963) Transplantation. , vol.1 , pp. 174-80
    • Abelev, G.I.1    Perova, S.D.2    Khramkova, N.I.3
  • 3
    • 0031972579 scopus 로고    scopus 로고
    • Screening for hepatocellular carcinoma
    • Collier J, Sherman M. Screening for hepatocellular carcinoma. Hepatology. 1998;27:273-8.
    • (1998) Hepatology. , vol.27 , pp. 273-8
    • Collier, J.1    Sherman, M.2
  • 4
    • 0028180445 scopus 로고
    • Prospective study of alpha-fetoprotein in cirrhotic patients monitored for development of hepatocellular carcinoma
    • Oka H, Tamori A, Kuroki T, et al. Prospective study of alpha-fetoprotein in cirrhotic patients monitored for development of hepatocellular carcinoma. Hepatology. 1994;19:61-6.
    • (1994) Hepatology. , vol.19 , pp. 61-6
    • Oka, H.1    Tamori, A.2    Kuroki, T.3
  • 5
    • 0034856294 scopus 로고    scopus 로고
    • Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver
    • Bruix J, Sherman M, Llovet JM, et al. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. J Hepatol. 2001;35:421-30.
    • (2001) J Hepatol. , vol.35 , pp. 421-30
    • Bruix, J.1    Sherman, M.2    Llovet, J.M.3
  • 6
    • 0021273094 scopus 로고
    • Des-gamma-carboxy (abnormal) prothrombin as a serum marker of primary hepato-cellular carcinoma
    • Liebman HA, Furie BC, Tong MJ, et al. Des-gamma-carboxy (abnormal) prothrombin as a serum marker of primary hepato-cellular carcinoma. N Eng J Med. 1984;310:1427-31.
    • (1984) N Eng J Med. , vol.310 , pp. 1427-31
    • Liebman, H.A.1    Furie, B.C.2    Tong, M.J.3
  • 7
    • 0024217002 scopus 로고
    • Plasma abnormal pro-thrombin levels in patients with small hepatocellular carcinoma
    • Tanabe Y, Ohnishi K, Nomura F, et al. Plasma abnormal pro-thrombin levels in patients with small hepatocellular carcinoma. Am J Gastroenterol. 1988;83:1386-9.
    • (1988) Am J Gastroenterol. , vol.83 , pp. 1386-9
    • Tanabe, Y.1    Ohnishi, K.2    Nomura, F.3
  • 8
    • 0025824756 scopus 로고
    • Clinical usefulness of des-gamma-carboxy prothrombin assay in early diagnosis of hepa-tocellular carcinoma
    • Fujiyama S, Izuno K, Gohshi K, et al. Clinical usefulness of des-gamma-carboxy prothrombin assay in early diagnosis of hepa-tocellular carcinoma. Dig Dis Sci. 1991;36:1787-92.
    • (1991) Dig Dis Sci. , vol.36 , pp. 1787-92
    • Fujiyama, S.1    Izuno, K.2    Gohshi, K.3
  • 9
    • 0029329801 scopus 로고
    • The role of tumor markers in the diagnosis of hepatocellular carcinoma, with spe-cial reference to the des-gamma-carboxy prothrombin
    • Grazi GL, Mazziotti A, Legnani C, et al. The role of tumor markers in the diagnosis of hepatocellular carcinoma, with spe-cial reference to the des-gamma-carboxy prothrombin. Liver Transpl Surg. 1995;1:249-55.
    • (1995) Liver Transpl Surg. , vol.1 , pp. 249-55
    • Grazi, G.L.1    Mazziotti, A.2    Legnani, C.3
  • 10
    • 0033048769 scopus 로고    scopus 로고
    • Serum des-gamma-car-boxy prothrombin levels determined by a new generation of sensitive immunoassays in patients with small-sized hepatocel-lular carcinoma
    • Nomura F, Ishijima M, Kuwa K, et al. Serum des-gamma-car-boxy prothrombin levels determined by a new generation of sensitive immunoassays in patients with small-sized hepatocel-lular carcinoma. Am J Gastroenterol. 1999;94:650-4.
    • (1999) Am J Gastroenterol. , vol.94 , pp. 650-4
    • Nomura, F.1    Ishijima, M.2    Kuwa, K.3
  • 11
    • 0025342730 scopus 로고
    • Plasma des-gamma-car-boxyprothrombin in the early stage of hepatocellular carcinoma
    • Tsai SL, Huang GT, Yang PM, et al. Plasma des-gamma-car-boxyprothrombin in the early stage of hepatocellular carcinoma. Hepatology. 1990;11:481-8.
    • (1990) Hepatology. , vol.11 , pp. 481-8
    • Tsai, S.L.1    Huang, G.T.2    Yang, P.M.3
  • 12
    • 0024803386 scopus 로고
    • Evaluation of des-gamma-carboxy prothrombin as a marker protein of hepatocel-lular carcinoma
    • Deyashiki Y, Nishioka Y, Takahashi K, et al. Evaluation of des-gamma-carboxy prothrombin as a marker protein of hepatocel-lular carcinoma. Cancer. 1989;64:2546-51.
    • (1989) Cancer. , vol.64 , pp. 2546-51
    • Deyashiki, Y.1    Nishioka, Y.2    Takahashi, K.3
  • 13
    • 0027130291 scopus 로고
    • Clinical evaluation of plasma des-gamma-carboxy prothrombin as a marker protein of hepatocellular carcinoma in patients with tumors of various sizes
    • Kasahara A, Hayashi N, Fusamoto H, et al. Clinical evaluation of plasma des-gamma-carboxy prothrombin as a marker protein of hepatocellular carcinoma in patients with tumors of various sizes. Dig Dis Sci. 1993;38:2170-6.
    • (1993) Dig Dis Sci. , vol.38 , pp. 2170-6
    • Kasahara, A.1    Hayashi, N.2    Fusamoto, H.3
  • 14
    • 0027939329 scopus 로고
    • Clinical significance of abnormal prothrombin (DCP) in relation to postoperative survival and prognosis in patients with hepatocellular carcinoma
    • Inoue S, Nakao A, Harada A, et al. Clinical significance of abnormal prothrombin (DCP) in relation to postoperative survival and prognosis in patients with hepatocellular carcinoma. Am J Gastroenterol. 1994;89:2222-6.
    • (1994) Am J Gastroenterol. , vol.89 , pp. 2222-6
    • Inoue, S.1    Nakao, A.2    Harada, A.3
  • 15
    • 0032781041 scopus 로고    scopus 로고
    • Use of serum PIVKA-II (DCP) determination for differentiation between benign and malignant liver diseases
    • Lamerz R, Runge M, Stieber P, et al. Use of serum PIVKA-II (DCP) determination for differentiation between benign and malignant liver diseases. Anticancer Res. 1999;19:2489-93.
    • (1999) Anticancer Res. , vol.19 , pp. 2489-93
    • Lamerz, R.1    Runge, M.2    Stieber, P.3
  • 16
    • 0038236531 scopus 로고    scopus 로고
    • Diagnostic value of protein induced by vitamin K absence (PIVKA-II) and hepatoma-specific band of serum gamma-glutamyl transferase (GGTII) as hepatocellular carcinoma markers complementary to alpha-fetoprotein
    • Cui R, He J, Zhang F, et al. Diagnostic value of protein induced by vitamin K absence (PIVKA-II) and hepatoma-specific band of serum gamma-glutamyl transferase (GGTII) as hepatocellular carcinoma markers complementary to alpha-fetoprotein. Br J Cancer. 2003;88:1878-82.
    • (2003) Br J Cancer. , vol.88 , pp. 1878-82
    • Cui, R.1    He, J.2    Zhang, F.3
  • 17
    • 30644467109 scopus 로고    scopus 로고
    • Usefulness of serum des-gamma-carboxy prothrombin in detection of hepatocellular car-cinoma
    • Wang CS, Lin CL, Lee HC, et al. Usefulness of serum des-gamma-carboxy prothrombin in detection of hepatocellular car-cinoma. World J Gastroenterol. 2005;11:6115-9.
    • (2005) World J Gastroenterol. , vol.11 , pp. 6115-9
    • Wang, C.S.1    Lin, C.L.2    Lee, H.C.3
  • 18
    • 0032080912 scopus 로고    scopus 로고
    • The usefulness of deter-mining des-gamma-carboxy prothrombin by sensitive enzyme immunoassay in the early diagnosis of patients with hepatocel-lular carcinoma
    • Mita Y, Aoyagi Y, Yanagi M, et al. The usefulness of deter-mining des-gamma-carboxy prothrombin by sensitive enzyme immunoassay in the early diagnosis of patients with hepatocel-lular carcinoma. Cancer. 1998;82:1643-8.
    • (1998) Cancer. , vol.82 , pp. 1643-8
    • Mita, Y.1    Aoyagi, Y.2    Yanagi, M.3
  • 19
    • 33748366782 scopus 로고    scopus 로고
    • Sensitivity and specificity of des-gamma-carboxy prothrombin for diagnosis of patients with hepatocellular carcinoma varies according to tumor size
    • Nakamura S, Nouso K, Sakaguchi K, et al. Sensitivity and specificity of des-gamma-carboxy prothrombin for diagnosis of patients with hepatocellular carcinoma varies according to tumor size. Am J Gastroenterol. 2006;101:2038-43.
    • (2006) Am J Gastroenterol. , vol.101 , pp. 2038-43
    • Nakamura, S.1    Nouso, K.2    Sakaguchi, K.3
  • 20
    • 0037698789 scopus 로고    scopus 로고
    • Des-gamma carboxypro-thrombin can differentiate hepatocellular carcinoma from nonmalignant chronic liver disease in American patients
    • Marrero JA, Su GL, Wei W, et al. Des-gamma carboxypro-thrombin can differentiate hepatocellular carcinoma from nonmalignant chronic liver disease in American patients. Hepa-tology. 2003;37:1114-21.
    • (2003) Hepatology. , vol.37 , pp. 1114-21
    • Marrero, J.A.1    Su, G.L.2    Wei, W.3
  • 21
    • 0028291568 scopus 로고
    • Protein induced by vitamin K absence or antagonist II as a prognostic marker in hepatocellular carcinoma. Comparison with alpha-fetoprotein
    • Suehiro T, Sugimachi K, Matsumata T, et al. Protein induced by vitamin K absence or antagonist II as a prognostic marker in hepatocellular carcinoma. Comparison with alpha-fetoprotein. Cancer. 1994;73:2464-71.
    • (1994) Cancer. , vol.73 , pp. 2464-71
    • Suehiro, T.1    Sugimachi, K.2    Matsumata, T.3
  • 22
    • 33847231604 scopus 로고    scopus 로고
    • Clinical evaluation of lens culinaris agglutinin-reactive alpha-fetoprotein and des-gamma-carboxy prothrombin in histologically proven hepatocellular carcinoma in the United States
    • Carr BI, Kanke F, Wise M, et al. Clinical evaluation of lens culinaris agglutinin-reactive alpha-fetoprotein and des-gamma-carboxy prothrombin in histologically proven hepatocellular carcinoma in the United States. Dig Dis Sci. 2007;52:776-82.
    • (2007) Dig Dis Sci. , vol.52 , pp. 776-82
    • Carr, B.I.1    Kanke, F.2    Wise, M.3
  • 23
    • 0035143887 scopus 로고    scopus 로고
    • The role of serum alpha-fetoprotein estimation in the diagnosis and management of hepatocellular carcinoma
    • Johnson PJ. The role of serum alpha-fetoprotein estimation in the diagnosis and management of hepatocellular carcinoma. Clin Liver Dis. 2001;5:145-59.
    • (2001) Clin Liver Dis. , vol.5 , pp. 145-59
    • Johnson, P.J.1
  • 24
    • 0032784523 scopus 로고    scopus 로고
    • Prognostic sig-nificance of anatomical resection and des-gamma-carboxy prothrombin in patients with hepatocellular carcinoma
    • Imamura H, Matsuyama Y, Miyagawa Y, et al. Prognostic sig-nificance of anatomical resection and des-gamma-carboxy prothrombin in patients with hepatocellular carcinoma. Br J Surg. 1999;86:1032-8.
    • (1999) Br J Surg. , vol.86 , pp. 1032-8
    • Imamura, H.1    Matsuyama, Y.2    Miyagawa, Y.3
  • 25
    • 33947575209 scopus 로고    scopus 로고
    • Prognostic factors for portal venous invasion in patients with hepatocellular carcinoma
    • Hagiwara S, Kudo M, Kawasaki T, et al. Prognostic factors for portal venous invasion in patients with hepatocellular carcinoma. J Gastroenterol. 2006;41:1214-9.
    • (2006) J Gastroenterol. , vol.41 , pp. 1214-9
    • Hagiwara, S.1    Kudo, M.2    Kawasaki, T.3
  • 26
    • 0034141402 scopus 로고    scopus 로고
    • Serum levels of des-gamma-carboxy prothrombin measured using the revised enzyme immunoassay kit with increased sensitivity in relation to clini-copathologic features of solitary hepatocellular carcinoma
    • Okuda H, Nakanishi T, Takatsu K, et al. Serum levels of des-gamma-carboxy prothrombin measured using the revised enzyme immunoassay kit with increased sensitivity in relation to clini-copathologic features of solitary hepatocellular carcinoma. Cancer. 2000;88:544-9.
    • (2000) Cancer. , vol.88 , pp. 544-9
    • Okuda, H.1    Nakanishi, T.2    Takatsu, K.3
  • 27
    • 33847634740 scopus 로고    scopus 로고
    • Clinicopathologic features of poorly differentiated hepatocellular carcinoma
    • Oishi K, Itamoto T, Amano H, et al. Clinicopathologic features of poorly differentiated hepatocellular carcinoma. J Surg Oncol. 2007;95:311-6.
    • (2007) J Surg Oncol. , vol.95 , pp. 311-6
    • Oishi, K.1    Itamoto, T.2    Amano, H.3
  • 28
    • 0034596475 scopus 로고    scopus 로고
    • Adoptive immuno-therapy to lower postsurgical recurrence rate of hepatocellular carcinoma: A randomized trial
    • Takayama T, Sekine T, Makuuchi M, et al. Adoptive immuno-therapy to lower postsurgical recurrence rate of hepatocellular carcinoma: a randomized trial. Lancet. 2000;356:802-7.
    • (2000) Lancet. , vol.356 , pp. 802-7
    • Takayama, T.1    Sekine, T.2    Makuuchi, M.3
  • 29
    • 69749091062 scopus 로고    scopus 로고
    • Diagnostic accuracy of tumor markers for hepatocellular carcinoma: A systematic review
    • Tateishi R, Yoshida H, Matsuyama Y, et al. Diagnostic accuracy of tumor markers for hepatocellular carcinoma: a systematic review. Hepatol Int. 2008;2:17-30
    • (2008) Hepatol Int. , vol.2 , pp. 17-30
    • Tateishi, R.1    Yoshida, H.2    Matsuyama, Y.3
  • 31
    • 0018079655 scopus 로고    scopus 로고
    • Basic principles of ROC analysis
    • Metz CE. Basic principles of ROC analysis. Semin Nucl Med. 1998;8:283-98.
    • (1998) Semin Nucl Med. , vol.8 , pp. 283-98
    • Metz, C.E.1
  • 32
    • 0035908491 scopus 로고    scopus 로고
    • Phases of biomarker devel-opment for early detection of cancer
    • Pepe MS, Etzioni R, Feng Z, et al. Phases of biomarker devel-opment for early detection of cancer. J Natl Cancer Inst. 2001;93:1054-61.
    • (2001) J Natl Cancer Inst. , vol.93 , pp. 1054-61
    • Pepe, M.S.1    Etzioni, R.2    Feng, Z.3
  • 33
    • 0026082855 scopus 로고
    • Clinical evaluation of plasma abnormal prothrombin (des-gamma-carboxy prothrombin) in hepatobiliary malignancies and other diseases
    • Nakao A, Suzuki Y, Issiki K, et al. Clinical evaluation of plasma abnormal prothrombin (des-gamma-carboxy prothrombin) in hepatobiliary malignancies and other diseases. Am J Gastroen-terol. 1991;86:62-6.
    • (1991) Am J Gastroen-terol. , vol.86 , pp. 62-6
    • Nakao, A.1    Suzuki, Y.2    Issiki, K.3
  • 34
    • 0022778810 scopus 로고
    • Des-gamma-carboxypro-thrombin assay in alcoholic cirrhotic patients with alpha-fetoprotein level slightly increased
    • Lefrere JJ, Gozin D, Lerable J, et al. Des-gamma-carboxypro-thrombin assay in alcoholic cirrhotic patients with alpha-fetoprotein level slightly increased. Hepatology. 1986;6:1066-7.
    • (1986) Hepatology. , vol.6 , pp. 1066-7
    • Lefrere, J.J.1    Gozin, D.2    Lerable, J.3
  • 35
    • 0032953265 scopus 로고    scopus 로고
    • Increase of serum des-gamma-carboxy prothrombin in alcoholic liver disease without hepatocellular carcinoma
    • Ohhira M, Ohtake T, Saito H, et al. Increase of serum des-gamma-carboxy prothrombin in alcoholic liver disease without hepatocellular carcinoma. Alcohol Clin Exp Res. 1999;23:67S-70S.
    • (1999) Alcohol Clin Exp Res. , vol.23
    • Ohhira, M.1    Ohtake, T.2    Saito, H.3
  • 36
    • 0033074462 scopus 로고    scopus 로고
    • Clinicopathologic signifi-cance of protein induced vitamin K absence or antagonist II and alpha-fetoprotein in hepatocellular carcinoma
    • Nakagawa T, Seki T, Shiro T, et al. Clinicopathologic signifi-cance of protein induced vitamin K absence or antagonist II and alpha-fetoprotein in hepatocellular carcinoma. Int J Oncol. 1999;14:281-6.
    • (1999) Int J Oncol. , vol.14 , pp. 281-6
    • Nakagawa, T.1    Seki, T.2    Shiro, T.3
  • 37
    • 0037308463 scopus 로고    scopus 로고
    • Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy
    • Imamura H, Matsuyama Y, Tanaka E, Ohkubo T, Hasegawa K, Miyagawa S, et al. Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy. J Hepatol. 2003;38:200-7.
    • (2003) J Hepatol. , vol.38 , pp. 200-7
    • Imamura, H.1    Matsuyama, Y.2    Tanaka, E.3    Ohkubo, T.4    Hasegawa, K.5    Miyagawa, S.6
  • 38
    • 0034255520 scopus 로고    scopus 로고
    • Different risk factors and prog-nosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma
    • Poon RT, Fan ST, Ng IO, et al. Different risk factors and prog-nosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma. Cancer. 2000;89:500-7.
    • (2000) Cancer. , vol.89 , pp. 500-7
    • Poon, R.T.1    Fan, S.T.2    Ng, I.O.3


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