메뉴 건너뛰기




Volumn 2, Issue 1, 2008, Pages 17-30

Diagnostic accuracy of tumor markers for hepatocellular carcinoma: A systematic review

Author keywords

Alphafetoprotein; Des gamma carboxyprothrombin; Hepatocellular carcinoma; Lens culinaris agglutinin reactive fraction of alphafetoprotein; Metaanalysis

Indexed keywords

ALPHA FETOPROTEIN; DECARBOXYPROTHROMBIN; LENS CULINARIS AGGLUTININ REACTIVE FRACTION OF ALPHA FETOPROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 69749091062     PISSN: 19360533     EISSN: 19360541     Source Type: Journal    
DOI: 10.1007/s12072-007-9038-x     Document Type: Review
Times cited : (159)

References (93)
  • 2
    • 0033545541 scopus 로고    scopus 로고
    • Rising incidence of hepatocellular carcinoma in the United States
    • El-Serag HB, Mason AC. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med 1999;340:745-50.
    • (1999) N Engl J Med , vol.340 , pp. 745-750
    • El-Serag, H.B.1    Mason, A.C.2
  • 5
    • 0027243462 scopus 로고
    • Risk factors for hepatocellular carcinoma among patients with chronic liver disease
    • Tsukuma H, Hiyama T, Tanaka S, Nakao M, Yabuuchi T, Kitamura T, et al. Risk factors for hepatocellular carcinoma among patients with chronic liver disease. N Engl J Med 1993;328:1797-801.
    • (1993) N Engl J Med , vol.328 , pp. 1797-1801
    • Tsukuma, H.1    Hiyama, T.2    Tanaka, S.3    Nakao, M.4    Yabuuchi, T.5    Kitamura, T.6
  • 6
    • 0029147454 scopus 로고
    • Characteristic difference of hepatocellular carcinoma between hepatitis B- and C- viral infection in Japan
    • Shiratori Y, Shiina S, Imamura M, Kato N, Kanai F, Okudaira T, et al. Characteristic difference of hepatocellular carcinoma between hepatitis B- and C- viral infection in Japan. Hepatology 1995;22:1027-33.
    • (1995) Hepatology , vol.22 , pp. 1027-1033
    • Shiratori, Y.1    Shiina, S.2    Imamura, M.3    Kato, N.4    Kanai, F.5    Okudaira, T.6
  • 7
    • 0028896179 scopus 로고
    • Occurrence of hepatocellular carcinoma and decompensation in western European patients with cirrhosis type B
    • for the EUROHEP Study Group on Hepatitis B Virus and Cirrhosis
    • Fattovich G, Giustina G, Schalm SW, Hadziyannis S, Sanchez-Tapias J, Almasio P, et al., for the EUROHEP Study Group on Hepatitis B Virus and Cirrhosis. Occurrence of hepatocellular carcinoma and decompensation in western European patients with cirrhosis type B. Hepatology 1995;21:77-82.
    • (1995) Hepatology , vol.21 , pp. 77-82
    • Fattovich, G.1    Giustina, G.2    Schalm, S.W.3    Hadziyannis, S.4    Sanchez-Tapias, J.5    Almasio, P.6
  • 8
    • 0028131871 scopus 로고
    • Risk of hepatocellular carcinoma in patients with cirrhosis in Japan. Analysis of infectious hepatitis viruses
    • Kato Y, Nakata K, Omagari K, Furukawa R, Kusumoto Y, Mori I, et al. Risk of hepatocellular carcinoma in patients with cirrhosis in Japan. Analysis of infectious hepatitis viruses. Cancer 1994;74:2234-8.
    • (1994) Cancer , vol.74 , pp. 2234-2238
    • Kato, Y.1    Nakata, K.2    Omagari, K.3    Furukawa, R.4    Kusumoto, Y.5    Mori, I.6
  • 9
    • 0028661203 scopus 로고
    • Screening for hepatocellular carcinoma in patients with Child's A cirrhosis: An 8-year prospective study by ultrasound and alphafetoprotein
    • Cottone M, Turri M, Caltagirone M, Parisi P, Orlando A, Fiorentino G, et al. Screening for hepatocellular carcinoma in patients with Child's A cirrhosis: An 8-year prospective study by ultrasound and alphafetoprotein. J Hepatol 1994;21:1029-34.
    • (1994) J Hepatol , vol.21 , pp. 1029-1034
    • Cottone, M.1    Turri, M.2    Caltagirone, M.3    Parisi, P.4    Orlando, A.5    Fiorentino, G.6
  • 10
    • 0033520109 scopus 로고    scopus 로고
    • Interferon therapy reduces the risk for hepatocellular carcinoma: National surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan
    • for the IHIT (Inhibition of Hepatocarcinogenesis by Interferon Therapy) Study Group
    • Yoshida H, Shiratori Y, Moriyama M, Arakawa Y, Ide T, Sata M, et al., for the IHIT (Inhibition of Hepatocarcinogenesis by Interferon Therapy) Study Group. Interferon therapy reduces the risk for hepatocellular carcinoma: National surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. Ann Intern Med 1999;131:174-81.
    • (1999) Ann Intern Med , vol.131 , pp. 174-181
    • Yoshida, H.1    Shiratori, Y.2    Moriyama, M.3    Arakawa, Y.4    Ide, T.5    Sata, M.6
  • 11
    • 0031041924 scopus 로고    scopus 로고
    • Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients
    • Fattovich G, Giustina G, Degos F, Tremolada F, Diodati G, Almasio P, et al. Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients. Gastroenterology 1997;112:463-72.
    • (1997) Gastroenterology , vol.112 , pp. 463-472
    • Fattovich, G.1    Giustina, G.2    Degos, F.3    Tremolada, F.4    Diodati, G.5    Almasio, P.6
  • 12
    • 0032862122 scopus 로고    scopus 로고
    • Accurate preoperative evaluation of liver mass lesions without fine-needle biopsy
    • Torzilli G, Minagawa M, Takayama T, Inoue K, Hui AM, Kubota K, et al. Accurate preoperative evaluation of liver mass lesions without fine-needle biopsy. Hepatology 1999;30:889-93.
    • (1999) Hepatology , vol.30 , pp. 889-893
    • Torzilli, G.1    Minagawa, M.2    Takayama, T.3    Inoue, K.4    Hui, A.M.5    Kubota, K.6
  • 13
    • 28844480321 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma
    • Bruix J, Sherman M. Management of hepatocellular carcinoma. Hepatology 2005;42:1208-36.
    • (2005) Hepatology , vol.42 , pp. 1208-1236
    • Bruix, J.1    Sherman, M.2
  • 14
    • 0002206864 scopus 로고
    • Alpha-fetoprotein
    • In: Read AE, editor. London: Butterworths
    • Kew MC. Alpha-fetoprotein. In: Read AE, editor. Modern trends in gastroenterology. London: Butterworths; 1975. p. 91.
    • (1975) Modern Trends in Gastroenterology , pp. 91
    • Kew, M.C.1
  • 15
    • 0029153698 scopus 로고
    • Screening for hepatocellular carcinoma in chronic carriers of hepatitis B virus: Incidence and prevalence of hepatocellular carcinoma in a North American urban population./
    • Sherman M, Peltekian KM, Lee C. Screening for hepatocellular carcinoma in chronic carriers of hepatitis B virus: Incidence and prevalence of hepatocellular carcinoma in a North American urban population. Hepatology 1995;22:432-8.
    • (1995) Hepatology , vol.22 , pp. 432-438
    • Sherman, M.1    Peltekian, K.M.2    Lee, C.3
  • 17
    • 0018092458 scopus 로고
    • Alpha-fetoprotein (AFP) in benign liver disease. Evidence that normal liver regeneration does not induce AFP synthesis
    • Alpert E, Feller ER. Alpha-fetoprotein (AFP) in benign liver disease. Evidence that normal liver regeneration does not induce AFP synthesis. Gastroenterology 1978;74:856-8.
    • (1978) Gastroenterology , vol.74 , pp. 856-858
    • Alpert, E.1    Feller, E.R.2
  • 18
    • 0021273094 scopus 로고
    • Des-gamma-carboxy (abnormal) prothrombin as a serum marker of primary hepatocellular carcinoma
    • Liebman HA, Furie BC, Tong MJ, Blanchard RA, Lo KJ, Lee SD, et al. Des-gamma-carboxy (abnormal) prothrombin as a serum marker of primary hepatocellular carcinoma. N Engl J Med 1984;310:1427-31.
    • (1984) N Engl J Med , vol.310 , pp. 1427-1431
    • Liebman, H.A.1    Furie, B.C.2    Tong, M.J.3    Blanchard, R.A.4    Lo, K.J.5    Lee, S.D.6
  • 19
    • 0023243522 scopus 로고
    • Production of abnormal prothrombin (des-gamma-carboxy prothrombin) by hepatocellular carcinoma. A clinical and experimental study
    • Okuda H, Obata H, Nakanishi T, Furukawa R, Hashimoto E. Production of abnormal prothrombin (des-gamma-carboxy prothrombin) by hepatocellular carcinoma. A clinical and experimental study. J Hepatol 1987;4:357-63.
    • (1987) J Hepatol , vol.4 , pp. 357-363
    • Okuda, H.1    Obata, H.2    Nakanishi, T.3    Furukawa, R.4    Hashimoto, E.5
  • 20
    • 0021854121 scopus 로고
    • Fucosylation of serum alpha-fetoprotein in patients with primary hepatocellular carcinoma
    • Aoyagi Y, Isemura M, Yosizawa Z, Suzuki Y, Sekine C, Ono T, et al. Fucosylation of serum alpha-fetoprotein in patients with primary hepatocellular carcinoma. Biochim Biophys Acta 1985;830:217-23.
    • (1985) Biochim Biophys Acta , vol.830 , pp. 217-223
    • Aoyagi, Y.1    Isemura, M.2    Yosizawa, Z.3    Suzuki, Y.4    Sekine, C.5    Ono, T.6
  • 21
    • 0027154890 scopus 로고
    • Early recognition of hepatocellular carcinoma based on altered profiles of alpha-fetoprotein
    • Sato Y, Nakata K, Kato Y, Shima M, Ishii N, Koji T, et al. Early recognition of hepatocellular carcinoma based on altered profiles of alpha-fetoprotein. N Engl J Med 1993;328:1802-6.
    • (1993) N Engl J Med , vol.328 , pp. 1802-1806
    • Sato, Y.1    Nakata, K.2    Kato, Y.3    Shima, M.4    Ishii, N.5    Koji, T.6
  • 22
    • 0032958169 scopus 로고    scopus 로고
    • Soluble interleukin-2 receptor levels in hepatocellular cancer: A more sensitive marker than alfa fetoprotein
    • Izzo F, Cremona F, Delrio P, Leonardi E, Castello G, Pignata S, et al. Soluble interleukin-2 receptor levels in hepatocellular cancer: A more sensitive marker than alfa fetoprotein. Ann Surg Oncol 1999;6:178-85.
    • (1999) Ann Surg Oncol , vol.6 , pp. 178-185
    • Izzo, F.1    Cremona, F.2    Delrio, P.3    Leonardi, E.4    Castello, G.5    Pignata, S.6
  • 23
    • 0033948531 scopus 로고    scopus 로고
    • Transforming growth factor beta1 and soluble Fas serum levels in hepatocellular carcinoma
    • Sacco R, Leuci D, Tortorella C, Fiore G, Marinosci F, Schiraldi O, et al. Transforming growth factor beta1 and soluble Fas serum levels in hepatocellular carcinoma. Cytokine 2000;12:811-4.
    • (2000) Cytokine , vol.12 , pp. 811-814
    • Sacco, R.1    Leuci, D.2    Tortorella, C.3    Fiore, G.4    Marinosci, F.5    Schiraldi, O.6
  • 24
    • 0034100047 scopus 로고    scopus 로고
    • Decreased function of peripheral blood dendritic cells in patients with hepatocellular carcinoma with hepatitis B and C virus infection
    • Kakumu S, Ito S, Ishikawa T, Mita Y, Tagaya T, Fukuzawa Y, et al. Decreased function of peripheral blood dendritic cells in patients with hepatocellular carcinoma with hepatitis B and C virus infection. J Gastroenterol Hepatol 2000;15:431-6.
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 431-436
    • Kakumu, S.1    Ito, S.2    Ishikawa, T.3    Mita, Y.4    Tagaya, T.5    Fukuzawa, Y.6
  • 26
    • 0028795817 scopus 로고
    • Meta-analytic methods for diagnostic test accuracy
    • discussion 31-2
    • Irwig L, Macaskill P, Glasziou P, Fahey M. Meta-analytic methods for diagnostic test accuracy. J Clin Epidemiol 1995; 48:119-30; discussion 31-2.
    • (1995) J Clin Epidemiol , vol.48 , pp. 119-130
    • Irwig, L.1    Macaskill, P.2    Glasziou, P.3    Fahey, M.4
  • 27
    • 0027290944 scopus 로고
    • Combining independent studies of a diagnostic test into a summary ROC curve: Data-analytic approaches and some additional considerations
    • Moses LE, Shapiro D, Littenberg B. Combining independent studies of a diagnostic test into a summary ROC curve: Data-analytic approaches and some additional considerations. Stat Med 1993;12:1293-316.
    • (1993) Stat Med , vol.12 , pp. 1293-1316
    • Moses, L.E.1    Shapiro, D.2    Littenberg, B.3
  • 28
    • 0037093923 scopus 로고    scopus 로고
    • Properties of the summary receiver operating characteristic (SROC) curve for diagnostic test data
    • Walter SD. Properties of the summary receiver operating characteristic (SROC) curve for diagnostic test data. Stat Med 2002;21:1237-56.
    • (2002) Stat Med , vol.21 , pp. 1237-1256
    • Walter, S.D.1
  • 29
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-34.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 33
    • 0036829984 scopus 로고    scopus 로고
    • Screening tests for hepatocellular carcinoma in patients with chronic hepatitis C: A systematic review
    • Gebo KA, Chander G, Jenckes MW, Ghanem KG, Herlong HF, Torbenson MS, et al. Screening tests for hepatocellular carcinoma in patients with chronic hepatitis C: A systematic review. Hepatology 2002;36:S84-92.
    • (2002) Hepatology , vol.36
    • Gebo, K.A.1    Chander, G.2    Jenckes, M.W.3    Ghanem, K.G.4    Herlong, H.F.5    Torbenson, M.S.6
  • 34
    • 0038482034 scopus 로고    scopus 로고
    • Test characteristics of alpha-fetoprotein for detecting hepatocellular carcinoma in patients with hepatitis C. A systematic review and critical analysis
    • Gupta S, Bent S, Kohlwes J. Test characteristics of alpha-fetoprotein for detecting hepatocellular carcinoma in patients with hepatitis C. A systematic review and critical analysis. Ann Intern Med 2003;139:46-50.
    • (2003) Ann Intern Med , vol.139 , pp. 46-50
    • Gupta, S.1    Bent, S.2    Kohlwes, J.3
  • 35
    • 0027074085 scopus 로고
    • Determination of optimum cutoff levels of plasma des-gamma-carboxy prothrombin and serum alpha-fetoprotein for the diagnosis of hepatocellular carcinoma using receiver operating characteristic curves
    • Fujiyama S, Izuno K, Yamasaki K, Sato T, Taketa K. Determination of optimum cutoff levels of plasma des-gamma-carboxy prothrombin and serum alpha-fetoprotein for the diagnosis of hepatocellular carcinoma using receiver operating characteristic curves. Tumour Biol 1992;13:316-23.
    • (1992) Tumour Biol , vol.13 , pp. 316-323
    • Fujiyama, S.1    Izuno, K.2    Yamasaki, K.3    Sato, T.4    Taketa, K.5
  • 36
    • 0035722375 scopus 로고    scopus 로고
    • Surveillance for hepatocellular carcinoma in patients with chronic viral hepatitis in the United States of America
    • Tong MJ, Blatt LM, Kao VW. Surveillance for hepatocellular carcinoma in patients with chronic viral hepatitis in the United States of America. J Gastroenterol Hepatol 2001;16:553-9.
    • (2001) J Gastroenterol Hepatol , vol.16 , pp. 553-559
    • Tong, M.J.1    Blatt, L.M.2    Kao, V.W.3
  • 37
    • 0028158071 scopus 로고
    • Prospective study of screening for hepatocellular carcinoma in Caucasian patients with cirrhosis
    • Pateron D, Ganne N, Trinchet JC, Aurousseau MH, Mal F, Meicler C, et al. Prospective study of screening for hepatocellular carcinoma in Caucasian patients with cirrhosis. J Hepatol 1994;20:65-71.
    • (1994) J Hepatol , vol.20 , pp. 65-71
    • Pateron, D.1    Ganne, N.2    Trinchet, J.C.3    Aurousseau, M.H.4    Mal, F.5    Meicler, C.6
  • 39
    • 0034877265 scopus 로고    scopus 로고
    • Clinical evaluation of lentil lectin-reactive alpha-fetoprotein-L3 in histology-proven hepatocellular carcinoma
    • Khien VV, Mao HV, Chinh TT, Ha PT, Bang MH, Lac BV, et al. Clinical evaluation of lentil lectin-reactive alpha-fetoprotein-L3 in histology-proven hepatocellular carcinoma. Int J Biol Markers 2001;16:105-11.
    • (2001) Int J Biol Markers , vol.16 , pp. 105-111
    • Khien, V.V.1    Mao, H.V.2    Chinh, T.T.3    Ha, P.T.4    Bang, M.H.5    Lac, B.V.6
  • 40
    • 0035056663 scopus 로고    scopus 로고
    • Serum alpha-fetoprotein for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: Influence of HBsAg and anti-HCV status
    • Trevisani F, D'Intino PE, Morselli-Labate AM, Mazzella G, Accogli E, Caraceni P, et al. Serum alpha-fetoprotein for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: influence of HBsAg and anti-HCV status. J Hepatol 2001;34:570-5.
    • (2001) J Hepatol , vol.34 , pp. 570-575
    • Trevisani, F.1    D'Intino, P.E.2    Morselli-Labate, A.M.3    Mazzella, G.4    Accogli, E.5    Caraceni, P.6
  • 41
    • 0033798307 scopus 로고    scopus 로고
    • Screening for hepatocellular carcinoma in Alaska natives infected with chronic hepatitis B: A 16-year population-based study
    • McMahon BJ, Bulkow L, Harpster A, Snowball M, Lanier A, Sacco F, et al. Screening for hepatocellular carcinoma in Alaska natives infected with chronic hepatitis B: A 16-year population-based study. Hepatology 2000;32:842-6.
    • (2000) Hepatology , vol.32 , pp. 842-846
    • McMahon, B.J.1    Bulkow, L.2    Harpster, A.3    Snowball, M.4    Lanier, A.5    Sacco, F.6
  • 42
    • 0032801344 scopus 로고    scopus 로고
    • The effectiveness of serum alpha-fetoprotein level in anti-HCV positive patients for screening hepatocellular carcinoma
    • Peng YC, Chan CS, Chen GH. The effectiveness of serum alpha-fetoprotein level in anti-HCV positive patients for screening hepatocellular carcinoma. Hepatogastroenterology 1999;46:3208-11.
    • (1999) Hepatogastroenterology , vol.46 , pp. 3208-3211
    • Peng, Y.C.1    Chan, C.S.2    Chen, G.H.3
  • 43
    • 0030863067 scopus 로고    scopus 로고
    • Usefulness of ED036 kit for measuring serum PIVKA-II levels in small hepatocellular carcinoma
    • Kuromatsu R, Tanaka M, Shimauchi Y, Shimada M, Tanikawa K, Watanabe K, et al. Usefulness of ED036 kit for measuring serum PIVKA-II levels in small hepatocellular carcinoma. J Gastroenterol 1997;32:507-12.
    • (1997) J Gastroenterol , vol.32 , pp. 507-512
    • Kuromatsu, R.1    Tanaka, M.2    Shimauchi, Y.3    Shimada, M.4    Tanikawa, K.5    Watanabe, K.6
  • 44
    • 0028808751 scopus 로고
    • The low positive rate of serum alpha-fetoprotein levels in hepatitis C virus antibody-positive patients with hepatocellular carcinoma
    • Furui J, Furukawa M, Kanematsu T. The low positive rate of serum alpha-fetoprotein levels in hepatitis C virus antibody-positive patients with hepatocellular carcinoma. Hepatogastroenterology 1995;42:445-9.
    • (1995) Hepatogastroenterology , vol.42 , pp. 445-449
    • Furui, J.1    Furukawa, M.2    Kanematsu, T.3
  • 45
    • 0029329801 scopus 로고
    • The role of tumor markers in the diagnosis of hepatocellular carcinoma, with special reference to the des-gamma-carboxy prothrombin
    • Grazi GL, Mazziotti A, Legnani C, Jovine E, Miniero R, Gallucci A, et al. The role of tumor markers in the diagnosis of hepatocellular carcinoma, with special reference to the des-gamma-carboxy prothrombin. Liver Transpl Surg 1995;1:249-55.
    • (1995) Liver Transpl Surg , vol.1 , pp. 249-255
    • Grazi, G.L.1    Mazziotti, A.2    Legnani, C.3    Jovine, E.4    Miniero, R.5    Gallucci, A.6
  • 46
    • 0028176803 scopus 로고
    • Frequency of raised alpha-fetoprotein level among Chinese patients with hepatocellular carcinoma related to hepatitis B and C
    • Tsai JF, Chang WY, Jeng JE, Ho MS, Lin ZY, Tsai JH. Frequency of raised alpha-fetoprotein level among Chinese patients with hepatocellular carcinoma related to hepatitis B and C. Br J Cancer 1994;69:1157-9.
    • (1994) Br J Cancer , vol.69 , pp. 1157-1159
    • Tsai, J.F.1    Chang, W.Y.2    Jeng, J.E.3    Ho, M.S.4    Lin, Z.Y.5    Tsai, J.H.6
  • 47
    • 0028180445 scopus 로고
    • Prospective study of alpha-fetoprotein in cirrhotic patients monitored for development of hepatocellular carcinoma
    • Oka H, Tamori A, Kuroki T, Kobayashi K, Yamamoto S. Prospective study of alpha-fetoprotein in cirrhotic patients monitored for development of hepatocellular carcinoma. Hepatology 1994;19:61-6.
    • (1994) Hepatology , vol.19 , pp. 61-66
    • Oka, H.1    Tamori, A.2    Kuroki, T.3    Kobayashi, K.4    Yamamoto, S.5
  • 48
    • 0027103944 scopus 로고
    • Prospective study on the diagnosis of hepatocellular carcinoma by using alpha-fetoprotein reactive to lentil lectin
    • Tu Z, Yin Z, Wu M. Prospective study on the diagnosis of hepatocellular carcinoma by using alpha-fetoprotein reactive to lentil lectin. Chin Med Sci J 1992;7:191-6.
    • (1992) Chin Med Sci J , vol.7 , pp. 191-196
    • Tu, Z.1    Yin, Z.2    Wu, M.3
  • 49
    • 0025364993 scopus 로고
    • Lectin-reactive profiles of alpha-fetoprotein characterizing hepatocellular carcinoma and related conditions
    • Taketa K, Sekiya C, Namiki M, Akamatsu K, Ohta Y, Endo Y, et al. Lectin-reactive profiles of alpha-fetoprotein characterizing hepatocellular carcinoma and related conditions. Gastroenterology 1990;99:508-18.
    • (1990) Gastroenterology , vol.99 , pp. 508-518
    • Taketa, K.1    Sekiya, C.2    Namiki, M.3    Akamatsu, K.4    Ohta, Y.5    Endo, Y.6
  • 50
    • 0024803386 scopus 로고
    • Evaluation of des-gamma-carboxy prothrombin as a marker protein of hepatocellular carcinoma
    • Deyashiki Y, Nishioka Y, Takahashi K, Kosaka Y, Suzuki K. Evaluation of des-gamma-carboxy prothrombin as a marker protein of hepatocellular carcinoma. Cancer 1989;64:2546-51.
    • (1989) Cancer , vol.64 , pp. 2546-2551
    • Deyashiki, Y.1    Nishioka, Y.2    Takahashi, K.3    Kosaka, Y.4    Suzuki, K.5
  • 51
    • 0024564537 scopus 로고
    • A comparison between des-gamma-carboxy prothrombin and alpha-fetoprotein as markers of hepatocellular carcinoma in southern African blacks
    • King MA, Kew MC, Kuyl JM, Atkinson PM. A comparison between des-gamma-carboxy prothrombin and alpha-fetoprotein as markers of hepatocellular carcinoma in southern African blacks. J Gastroenterol Hepatol 1989;4:17-24.
    • (1989) J Gastroenterol Hepatol , vol.4 , pp. 17-24
    • King, M.A.1    Kew, M.C.2    Kuyl, J.M.3    Atkinson, P.M.4
  • 52
    • 0023836388 scopus 로고
    • The fucosylation index of alpha-fetoprotein and its usefulness in the early diagnosis of hepatocellular carcinoma
    • Aoyagi Y, Suzuki Y, Isemura M, Nomoto M, Sekine C, Igarashi K, et al. The fucosylation index of alpha-fetoprotein and its usefulness in the early diagnosis of hepatocellular carcinoma. Cancer 1988;61:769-74.
    • (1988) Cancer , vol.61 , pp. 769-774
    • Aoyagi, Y.1    Suzuki, Y.2    Isemura, M.3    Nomoto, M.4    Sekine, C.5    Igarashi, K.6
  • 53
    • 0022894647 scopus 로고
    • Evaluation of a monoclonal immunoenzymometric assay for alpha-fetoprotein
    • Chan DW, Kelsten M, Rock R, Bruzek D. Evaluation of a monoclonal immunoenzymometric assay for alpha-fetoprotein. Clin Chem 1986;32:1318-22.
    • (1986) Clin Chem , vol.32 , pp. 1318-1322
    • Chan, D.W.1    Kelsten, M.2    Rock, R.3    Bruzek, D.4
  • 54
    • 0029090315 scopus 로고
    • Diagnosis of hepatocellular carcinoma by concanavalin A affinity electrophoresis of serum alpha-fetoprotein
    • Saitoh S, Ikeda K, Koida I, Suzuki Y, Kobayashi M, Tsubota A, et al. Diagnosis of hepatocellular carcinoma by concanavalin A affinity electrophoresis of serum alpha-fetoprotein. Cancer 1995;76:1139-44.
    • (1995) Cancer , vol.76 , pp. 1139-1144
    • Saitoh, S.1    Ikeda, K.2    Koida, I.3    Suzuki, Y.4    Kobayashi, M.5    Tsubota, A.6
  • 56
    • 0031879640 scopus 로고    scopus 로고
    • Outcome of 67 patients with hepatocellular cancer detected during screening of 1125 patients with chronic hepatitis
    • Izzo F, Cremona F, Ruffolo F, Palaia R, Parisi V, Curley SA. Outcome of 67 patients with hepatocellular cancer detected during screening of 1125 patients with chronic hepatitis. Ann Surg 1998;227:513-8.
    • (1998) Ann Surg , vol.227 , pp. 513-518
    • Izzo, F.1    Cremona, F.2    Ruffolo, F.3    Palaia, R.4    Parisi, V.5    Curley, S.A.6
  • 57
    • 17944402697 scopus 로고    scopus 로고
    • Utility of alpha-fetoprotein (AFP) in the screening of patients with virus-related chronic liver disease: Does different viral etiology influence AFP levels in HCC? A study in 350 western patients
    • Cedrone A, Covino M, Caturelli E, Pompili M, Lorenzelli G, Villani MR, et al. Utility of alpha-fetoprotein (AFP) in the screening of patients with virus-related chronic liver disease: Does different viral etiology influence AFP levels in HCC? A study in 350 western patients. Hepatogastroenterology 2000;47:1654-8.
    • (2000) Hepatogastroenterology , vol.47 , pp. 1654-1658
    • Cedrone, A.1    Covino, M.2    Caturelli, E.3    Pompili, M.4    Lorenzelli, G.5    Villani, M.R.6
  • 58
    • 0036329916 scopus 로고    scopus 로고
    • Racial differences in effectiveness of alpha-fetoprotein for diagnosis of hepatocellular carcinoma in hepatitis C virus cirrhosis
    • Nguyen MH, Garcia RT, Simpson PW, Wright TL, Keeffe EB. Racial differences in effectiveness of alpha-fetoprotein for diagnosis of hepatocellular carcinoma in hepatitis C virus cirrhosis. Hepatology 2002;36:410-7.
    • (2002) Hepatology , vol.36 , pp. 410-417
    • Nguyen, M.H.1    Garcia, R.T.2    Simpson, P.W.3    Wright, T.L.4    Keeffe, E.B.5
  • 59
    • 0031825234 scopus 로고    scopus 로고
    • Sonographic screening for hepatocellular carcinoma in patients with chronic hepatitis or cirrhosis: An evaluation
    • Larcos G, Sorokopud H, Berry G, Farrell GC. Sonographic screening for hepatocellular carcinoma in patients with chronic hepatitis or cirrhosis: An evaluation. Am J Roentgenol 1998;171:433-5.
    • (1998) Am J Roentgenol , vol.171 , pp. 433-435
    • Larcos, G.1    Sorokopud, H.2    Berry, G.3    Farrell, G.C.4
  • 60
    • 0029143545 scopus 로고
    • Clinical evaluation of serum alpha-fetoprotein and circulating immune complexes as tumour markers of hepatocellular carcinoma
    • Tsai JF, Jeng JE, Ho MS, Chang WY, Lin ZY, Tsai JH. Clinical evaluation of serum alpha-fetoprotein and circulating immune complexes as tumour markers of hepatocellular carcinoma. Br J Cancer 1995;72:442-6.
    • (1995) Br J Cancer , vol.72 , pp. 442-446
    • Tsai, J.F.1    Jeng, J.E.2    Ho, M.S.3    Chang, W.Y.4    Lin, Z.Y.5    Tsai, J.H.6
  • 61
    • 0030914165 scopus 로고    scopus 로고
    • Detection of hepatocellular cancer during screening of 1125 patients with chronic hepatitis virus infection
    • Izzo F, Cremona F, Ruffolo F, Palaia R, Parisi V, Curley S. Detection of hepatocellular cancer during screening of 1125 patients with chronic hepatitis virus infection. J Chemother 1997;9:151-2.
    • (1997) J Chemother , vol.9 , pp. 151-152
    • Izzo, F.1    Cremona, F.2    Ruffolo, F.3    Palaia, R.4    Parisi, V.5    Curley, S.6
  • 62
    • 0029103345 scopus 로고
    • Identification and screening of 416 patients with chronic hepatitis at high risk to develop hepatocellular cancer
    • discussion 80-3
    • Curley SA, Izzo F, Gallipoli A, de Bellis M, Cremona F, Parisi V. Identification and screening of 416 patients with chronic hepatitis at high risk to develop hepatocellular cancer. Ann Surg 1995;222:375-80; discussion 80-3
    • (1995) Ann Surg , vol.222 , pp. 375-380
    • Curley, S.A.1    Izzo, F.2    Gallipoli, A.3    de Bellis, M.4    Cremona, F.5    Parisi, V.6
  • 63
    • 0034122117 scopus 로고    scopus 로고
    • Sensitivity of commonly available screening tests in detecting hepatocellular carcinoma in cirrhotic patients undergoing liver transplantation
    • Gambarin-Gelwan M, Wolf DC, Shapiro R, Schwartz ME, Min AD. Sensitivity of commonly available screening tests in detecting hepatocellular carcinoma in cirrhotic patients undergoing liver transplantation. Am J Gastroenterol 2000;95:1535-8.
    • (2000) Am J Gastroenterol , vol.95 , pp. 1535-1538
    • Gambarin-Gelwan, M.1    Wolf, D.C.2    Shapiro, R.3    Schwartz, M.E.4    Min, A.D.5
  • 64
    • 0029124120 scopus 로고
    • Early detection of hepatocellular carcinoma associated with cirrhosis by combined assay of des-gamma-carboxy prothrombin and alpha-fetoprotein: A prospective study
    • Izuno K, Fujiyama S, Yamasaki K, Sato M, Sato T. Early detection of hepatocellular carcinoma associated with cirrhosis by combined assay of des-gamma-carboxy prothrombin and alpha-fetoprotein: A prospective study. Hepatogastroenterology 1995;42:387-93.
    • (1995) Hepatogastroenterology , vol.42 , pp. 387-393
    • Izuno, K.1    Fujiyama, S.2    Yamasaki, K.3    Sato, M.4    Sato, T.5
  • 65
    • 0027229211 scopus 로고
    • A multivariate analysis of risk factors for hepatocellular carcinogenesis: A prospective observation of 795 patients with viral and alcoholic cirrhosis
    • Ikeda K, Saitoh S, Koida I, Arase Y, Tsubota A, Chayama K, et al. A multivariate analysis of risk factors for hepatocellular carcinogenesis: a prospective observation of 795 patients with viral and alcoholic cirrhosis. Hepatology 1993;18:47-53.
    • (1993) Hepatology , vol.18 , pp. 47-53
    • Ikeda, K.1    Saitoh, S.2    Koida, I.3    Arase, Y.4    Tsubota, A.5    Chayama, K.6
  • 66
    • 18744419424 scopus 로고    scopus 로고
    • A prospective multicenter study of hepatocellular carcinoma in Italian hemophiliacs with chronic hepatitis C
    • for the Study Group of the Association of Italian Hemophilia Centers
    • Tradati F, Colombo M, Mannucci PM, Rumi MG, De Fazio C, Gamba G, et al., for the Study Group of the Association of Italian Hemophilia Centers. A prospective multicenter study of hepatocellular carcinoma in Italian hemophiliacs with chronic hepatitis C. Blood 1998;91:1173-7.
    • (1998) Blood , vol.91 , pp. 1173-1177
    • Tradati, F.1    Colombo, M.2    Mannucci, P.M.3    Rumi, M.G.4    De Fazio, C.5    Gamba, G.6
  • 67
    • 0029946856 scopus 로고    scopus 로고
    • Ultrasound follow-up of patients at risk for hepatocellular carcinoma: Results of a prospective study on 360 cases
    • Solmi L, Primerano AM, Gandolfi L. Ultrasound follow-up of patients at risk for hepatocellular carcinoma: Results of a prospective study on 360 cases. Am J Gastroenterol 1996;91:1189-94.
    • (1996) Am J Gastroenterol , vol.91 , pp. 1189-1194
    • Solmi, L.1    Primerano, A.M.2    Gandolfi, L.3
  • 68
    • 0028661203 scopus 로고
    • Screening for hepatocellular carcinoma in patients with Child's A cirrhosis: An 8-year prospective study by ultrasound and alphafetoprotein
    • Cottone M, Turri M, Caltagirone M, Parisi P, Orlando A, Fiorentino G, et al. Screening for hepatocellular carcinoma in patients with Child's A cirrhosis: An 8-year prospective study by ultrasound and alphafetoprotein. J Hepatol 1994;21:1029-34.
    • (1994) J Hepatol , vol.21 , pp. 1029-1034
    • Cottone, M.1    Turri, M.2    Caltagirone, M.3    Parisi, P.4    Orlando, A.5    Fiorentino, G.6
  • 69
    • 0023882166 scopus 로고
    • Plasma abnormal prothrombin (des-gamma-carboxy prothrombin) as a marker of hepatocellular carcinoma
    • Fujiyama S, Morishita T, Hashiguchi O, Sato T. Plasma abnormal prothrombin (des-gamma-carboxy prothrombin) as a marker of hepatocellular carcinoma. Cancer 1988;61:1621-8.
    • (1988) Cancer , vol.61 , pp. 1621-1628
    • Fujiyama, S.1    Morishita, T.2    Hashiguchi, O.3    Sato, T.4
  • 70
    • 0036215258 scopus 로고    scopus 로고
    • Early diagnosis of hepatocellular carcinoma using a sensitive assay for serum des-gamma-carboxy prothrombin: A prospective study
    • Ikoma J, Kaito M, Ishihara T, Nakagawa N, Kamei A, Fujita N, et al. Early diagnosis of hepatocellular carcinoma using a sensitive assay for serum des-gamma-carboxy prothrombin: A prospective study. Hepatogastroenterology 2002;49:235-8.
    • (2002) Hepatogastroenterology , vol.49 , pp. 235-238
    • Ikoma, J.1    Kaito, M.2    Ishihara, T.3    Nakagawa, N.4    Kamei, A.5    Fujita, N.6
  • 71
    • 0027130291 scopus 로고
    • Clinical evaluation of plasma des-gamma-carboxy prothrombin as a marker protein of hepatocellular carcinoma in patients with tumors of various sizes
    • Kasahara A, Hayashi N, Fusamoto H, Kawada Y, Imai Y, Yamamoto H, et al. Clinical evaluation of plasma des-gamma-carboxy prothrombin as a marker protein of hepatocellular carcinoma in patients with tumors of various sizes. Dig Dis Sci 1993;38:2170-6.
    • (1993) Dig Dis Sci , vol.38 , pp. 2170-2176
    • Kasahara, A.1    Hayashi, N.2    Fusamoto, H.3    Kawada, Y.4    Imai, Y.5    Yamamoto, H.6
  • 72
    • 0023950388 scopus 로고
    • Ultrasonography and alpha-fetoprotein in diagnosis of hepatocellular carcinoma in cirrhosis
    • Maringhini A, Cottone M, Sciarrino E, Marceno MP, La Seta F, Fusco G, et al. Ultrasonography and alpha-fetoprotein in diagnosis of hepatocellular carcinoma in cirrhosis. Dig Dis Sci 1988;33:47-51.
    • (1988) Dig Dis Sci , vol.33 , pp. 47-51
    • Maringhini, A.1    Cottone, M.2    Sciarrino, E.3    Marceno, M.P.4    La Seta, F.5    Fusco, G.6
  • 73
    • 0032080912 scopus 로고    scopus 로고
    • The usefulness of determining des-gamma-carboxy prothrombin by sensitive enzyme immunoassay in the early diagnosis of patients with hepatocellular carcinoma
    • Mita Y, Aoyagi Y, Yanagi M, Suda T, Suzuki Y, Asakura H. The usefulness of determining des-gamma-carboxy prothrombin by sensitive enzyme immunoassay in the early diagnosis of patients with hepatocellular carcinoma. Cancer 1998;82:1643-8.
    • (1998) Cancer , vol.82 , pp. 1643-1648
    • Mita, Y.1    Aoyagi, Y.2    Yanagi, M.3    Suda, T.4    Suzuki, Y.5    Asakura, H.6
  • 74
    • 0030018852 scopus 로고    scopus 로고
    • Determination of serum des-gamma-carboxy prothrombin levels in patients with small-sized hepatocellular carcinoma: Comparison of the conventional enzyme immunoassay and two modified methods
    • Nomura F, Ishijima M, Horikoshi A, Nakai T, Ohnishi K. Determination of serum des-gamma-carboxy prothrombin levels in patients with small-sized hepatocellular carcinoma: Comparison of the conventional enzyme immunoassay and two modified methods. Am J Gastroenterol 1996;91:1380-3.
    • (1996) Am J Gastroenterol , vol.91 , pp. 1380-1383
    • Nomura, F.1    Ishijima, M.2    Horikoshi, A.3    Nakai, T.4    Ohnishi, K.5
  • 75
    • 0033048769 scopus 로고    scopus 로고
    • Serum des-gamma-carboxy prothrombin levels determined by a new generation of sensitive immunoassays in patients with small-sized hepatocellular carcinoma
    • Nomura F, Ishijima M, Kuwa K, Tanaka N, Nakai T, Ohnishi K. Serum des-gamma-carboxy prothrombin levels determined by a new generation of sensitive immunoassays in patients with small-sized hepatocellular carcinoma. Am J Gastroenterol 1999;94:650-4.
    • (1999) Am J Gastroenterol , vol.94 , pp. 650-654
    • Nomura, F.1    Ishijima, M.2    Kuwa, K.3    Tanaka, N.4    Nakai, T.5    Ohnishi, K.6
  • 76
    • 0035702588 scopus 로고    scopus 로고
    • Multicenter prospective analysis of newly diagnosed hepatocellular carcinoma with respect to the percentage of lens culinaris agglutinin-reactive alpha-fetoprotein
    • Oka H, Saito A, Ito K, Kumada T, Satomura S, Kasugai H, et al. Multicenter prospective analysis of newly diagnosed hepatocellular carcinoma with respect to the percentage of lens culinaris agglutinin-reactive alpha-fetoprotein. J Gastroenterol Hepatol 2001;16:1378-83.
    • (2001) J Gastroenterol Hepatol , vol.16 , pp. 1378-1383
    • Oka, H.1    Saito, A.2    Ito, K.3    Kumada, T.4    Satomura, S.5    Kasugai, H.6
  • 77
    • 0033457907 scopus 로고    scopus 로고
    • Clinical utility of simultaneous measurement of serum high-sensitivity des-gamma-carboxy prothrombin and lens culinaris agglutinin A-reactive alpha-fetoprotein in patients with small hepatocellular carcinoma
    • Sassa T, Kumada T, Nakano S, Uematsu T. Clinical utility of simultaneous measurement of serum high-sensitivity des-gamma-carboxy prothrombin and lens culinaris agglutinin A-reactive alpha-fetoprotein in patients with small hepatocellular carcinoma. Eur J Gastroenterol Hepatol 1999;11:1387-92.
    • (1999) Eur J Gastroenterol Hepatol , vol.11 , pp. 1387-1392
    • Sassa, T.1    Kumada, T.2    Nakano, S.3    Uematsu, T.4
  • 78
    • 0028037521 scopus 로고
    • Serum des-gamma-carboxyprothrombin concentration determined by the avidin-biotin complex method in small hepatocellular carcinomas
    • Saitoh S, Ikeda K, Koida I, Tsubota A, Arase Y, Chayama K, et al. Serum des-gamma-carboxyprothrombin concentration determined by the avidin-biotin complex method in small hepatocellular carcinomas. Cancer 1994;74:2918-23.
    • (1994) Cancer , vol.74 , pp. 2918-2923
    • Saitoh, S.1    Ikeda, K.2    Koida, I.3    Tsubota, A.4    Arase, Y.5    Chayama, K.6
  • 79
    • 0034146463 scopus 로고    scopus 로고
    • A simultaneous monitoring of lens culinaris agglutinin A-reactive alpha-fetoprotein and des-gamma-carboxy prothrombin as an early diagnosis of hepatocellular carcinoma in the follow-up of cirrhotic patients
    • Shimauchi Y, Tanaka M, Kuromatsu R, Ogata R, Tateishi Y, Itano S, et al. A simultaneous monitoring of lens culinaris agglutinin A-reactive alpha-fetoprotein and des-gamma-carboxy prothrombin as an early diagnosis of hepatocellular carcinoma in the follow-up of cirrhotic patients. Oncol Rep 2000;7:249-56.
    • (2000) Oncol Rep , vol.7 , pp. 249-256
    • Shimauchi, Y.1    Tanaka, M.2    Kuromatsu, R.3    Ogata, R.4    Tateishi, Y.5    Itano, S.6
  • 80
    • 0029099151 scopus 로고
    • A clinical study of lectin-reactive alpha-fetoprotein as an early indicator of hepatocellular carcinoma in the follow-up of cirrhotic patients
    • Shiraki K, Takase K, Tameda Y, Hamada M, Kosaka Y, Nakano T. A clinical study of lectin-reactive alpha-fetoprotein as an early indicator of hepatocellular carcinoma in the follow-up of cirrhotic patients. Hepatology 1995;22:802-7.
    • (1995) Hepatology , vol.22 , pp. 802-807
    • Shiraki, K.1    Takase, K.2    Tameda, Y.3    Hamada, M.4    Kosaka, Y.5    Nakano, T.6
  • 81
    • 0028291568 scopus 로고
    • Protein induced by vitamin K absence or antagonist II as a prognostic marker in hepatocellular carcinoma. Comparison with alpha-fetoprotein
    • Suehiro T, Sugimachi K, Matsumata T, Itasaka H, Taketomi A, Maeda T. Protein induced by vitamin K absence or antagonist II as a prognostic marker in hepatocellular carcinoma. Comparison with alpha-fetoprotein. Cancer 1994;73:2464-71.
    • (1994) Cancer , vol.73 , pp. 2464-2471
    • Suehiro, T.1    Sugimachi, K.2    Matsumata, T.3    Itasaka, H.4    Taketomi, A.5    Maeda, T.6
  • 82
    • 0027422524 scopus 로고
    • A collaborative study for the evaluation of lectin-reactive alpha-fetoproteins in early detection of hepatocellular carcinoma
    • Taketa K, Endo Y, Sekiya C, Tanikawa K, Koji T, Taga H, et al. A collaborative study for the evaluation of lectin-reactive alpha-fetoproteins in early detection of hepatocellular carcinoma. Cancer Res 1993;53:5419-23.
    • (1993) Cancer Res , vol.53 , pp. 5419-5423
    • Taketa, K.1    Endo, Y.2    Sekiya, C.3    Tanikawa, K.4    Koji, T.5    Taga, H.6
  • 83
    • 0024217002 scopus 로고
    • Plasma abnormal prothrombin levels in patients with small hepatocellular carcinoma
    • Tanabe Y, Ohnishi K, Nomura F, Iida S. Plasma abnormal prothrombin levels in patients with small hepatocellular carcinoma. Am J Gastroenterol 1988;83:1386-9.
    • (1988) Am J Gastroenterol , vol.83 , pp. 1386-1389
    • Tanabe, Y.1    Ohnishi, K.2    Nomura, F.3    Iida, S.4
  • 84
    • 0025342730 scopus 로고
    • Plasma des-gamma-carboxyprothrombin in the early stage of hepatocellular carcinoma
    • Tsai SL, Huang GT, Yang PM, Sheu JC, Sung JL, Chen DS. Plasma des-gamma-carboxyprothrombin in the early stage of hepatocellular carcinoma. Hepatology 1990;11:481-8.
    • (1990) Hepatology , vol.11 , pp. 481-488
    • Tsai, S.L.1    Huang, G.T.2    Yang, P.M.3    Sheu, J.C.4    Sung, J.L.5    Chen, D.S.6
  • 85
    • 0033773681 scopus 로고    scopus 로고
    • Does surveillance for hepatocellular carcinoma in HCV cirrhotic patients improve treatment outcome mainly due to better clinical status at diagnosis?
    • Giannini E, Arzani L, Borro P, Botta F, Fasoli A, Risso D, et al. Does surveillance for hepatocellular carcinoma in HCV cirrhotic patients improve treatment outcome mainly due to better clinical status at diagnosis? Hepatogastroenterology 2000;47:1395-8.
    • (2000) Hepatogastroenterology , vol.47 , pp. 1395-1398
    • Giannini, E.1    Arzani, L.2    Borro, P.3    Botta, F.4    Fasoli, A.5    Risso, D.6
  • 86
    • 0035253469 scopus 로고    scopus 로고
    • Des-gamma-carboxy prothrombin as a useful predisposing factor for the development of portal venous invasion in patients with hepatocellular carcinoma: A prospective analysis of 227 patients
    • Koike Y, Shiratori Y, Sato S, Obi S, Teratani T, Imamura M, et al. Des-gamma-carboxy prothrombin as a useful predisposing factor for the development of portal venous invasion in patients with hepatocellular carcinoma: A prospective analysis of 227 patients. Cancer 2001;91:561-9.
    • (2001) Cancer , vol.91 , pp. 561-569
    • Koike, Y.1    Shiratori, Y.2    Sato, S.3    Obi, S.4    Teratani, T.5    Imamura, M.6
  • 87
    • 0032784523 scopus 로고    scopus 로고
    • Prognostic significance of anatomical resection and des-gamma-carboxy prothrombin in patients with hepatocellular carcinoma
    • Imamura H, Matsuyama Y, Miyagawa Y, Ishida K, Shimada R, Miyagawa S, et al. Prognostic significance of anatomical resection and des-gamma-carboxy prothrombin in patients with hepatocellular carcinoma. Br J Surg 1999;86:1032-8.
    • (1999) Br J Surg , vol.86 , pp. 1032-1038
    • Imamura, H.1    Matsuyama, Y.2    Miyagawa, Y.3    Ishida, K.4    Shimada, R.5    Miyagawa, S.6
  • 88
    • 0024578397 scopus 로고
    • Publication bias and dissemination of clinical research
    • Begg CB, Berlin JA. Publication bias and dissemination of clinical research. J Natl Cancer Inst 1989;81:107-15.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 107-115
    • Begg, C.B.1    Berlin, J.A.2
  • 92
    • 0024541162 scopus 로고
    • Alpha-fetoprotein monitoring in Chinese patients with chronic hepatitis B virus infection: Role in the early detection of hepatocellular carcinoma
    • Lok AS, Lai CL. Alpha-fetoprotein monitoring in Chinese patients with chronic hepatitis B virus infection: Role in the early detection of hepatocellular carcinoma. Hepatology 1989;9:110-5.
    • (1989) Hepatology , vol.9 , pp. 110-115
    • Lok, A.S.1    Lai, C.L.2
  • 93
    • 69749090745 scopus 로고    scopus 로고
    • The Study Group for Evidence Based Guideline for the Diagnosis and Treatment of Hepatocellular Carcinoma. Tokyo: Kanehara & Co
    • The Study Group for Evidence Based Guideline for the Diagnosis and Treatment of Hepatocellular Carcinoma. Evidence based guideline for the diagnosis and treatment of hepatocellular carcinoma. Tokyo: Kanehara & Co; 2005.
    • (2005) Evidence Based Guideline for the Diagnosis and Treatment of Hepatocellular Carcinoma


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.