Blockade of ethanol-induced potentiation of glycine receptors by a peptide that interferes with Gβγ binding

Journal of Pharmacology and Experimental Therapeutics

Volumn 331, Issue 3, 2009, Pages 933-939

  Guzman, Leonardo ^a   Moraga Cid, Gustavo ^a   Avila, Ariel ^a   Figueroa, Maximiliano ^a   Yevenes, Gonzalo E ^a   Fuentealba, Jorge ^a   Aguayo, Luis G ^a  

^a UNIVERSITY OF CONCEPCIÓN   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BACLOFEN; CYTOKINE; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; GLUTATHIONE TRANSFERASE; GLYCINE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; PEPTIDE; PEPTIDE RQH; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID B RECEPTOR; G PROTEIN BETA GAMMA; G-PROTEIN BETA GAMMA; GABA TYPE B RECEPTOR, SUBUNIT 1; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; HYBRID PROTEIN; PEPTIDE FRAGMENT; PROTEIN SUBUNIT;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG POTENTIATION; ENZYME ASSAY; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PURIFICATION; AMINO ACID SEQUENCE; BINDING SITE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ELECTROPHYSIOLOGY; ESCHERICHIA COLI; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; BINDING SITES; CELL LINE; ELECTROPHYSIOLOGY; ESCHERICHIA COLI; ETHANOL; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GLUTATHIONE TRANSFERASE; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RECEPTORS, GABA-B; RECEPTORS, GLYCINE; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 73349101073     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.160440     Document Type: Article

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