Comparison of a rapid immunoassay for antibodies to the C6 antigen with conventional tests for antibodies to Borrelia burgdorferi in dogs in Europe

Veterinary Record

Volumn 165, Issue 20, 2009, Pages 594-597

  Gerber, B ^a   Haug, K ^a   Eichenberger, S ^a   Reusch, C E ^a   Wittenbrink, M M ^b  

^a Clinic for Small Animal Internal Medicine   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BORRELIA BURGDORFERI; CANIS FAMILIARIS;

EID: 73049109077     PISSN: 00424900     EISSN: None     Source Type: Journal    
DOI: 10.1136/vr.165.20.594     Document Type: Article

References (29)

1. BACON, R. M., BIGGERSTAFF, B. J., SCHRIEFER, M. E., GILMORE, R. D., Jr, PHILIPP, M. T., STEERE, A. C., WORMSER, G. P., MARQUES, A. R. & JOHNSON, B. J. (2003) Serodiagnosis of Lyme disease by kinetic enzyme-tinked immunosorbent assay using recombinant VlsEl or peptide antigens of Borrelia burgdorferi compared with 2-tiered testing using whole-cell lysates. Journal of Infectious Diseases 187, 1187-1199
2. DRESSLER, F., ACKERMANN, R. & STEERE. A. C. (1994) Antibody responses to the three genomic groups of Borrelia burgdorferi in European Lyme borrelosis. Journal of Infectious Diseases 169, 313-318
3. GAUTHIER, D. T. & MANSFIELD, L. S. (1999) Western immunoblot analysis for distinguishing vaccination and infectious status with Borrelia burgdorferi (Lyme disease) in dogs. Journal of Veterinary Diagnostic Investigation 11, 259-265
4. GERBER, B., EICHENBERGER, S., WITTENRINK, M. M. & REUSCH, C. E. (2007) Increased prevalence of Borrelia burgdorferi infections in Bernese Mountain dogs: a possible breed disposition. BioMed Central Veterinary Research 3, 15
5. GERBER, B., HAUG, K., EICHENBERGER, S., REUSCH, C. E. & WITTENBRINK, M. M. (2009) Follow-up of Bernese Mountain dogs and other dogs with serologically diagnosed Borrelia burgdorferi infection: what happens to seropositive animals? BioMed Central Veterinary Research 5, 18
6. GOLDSTEIN, R. E., CORDNER, A. P., SANDLER, J. L, BELLOHUSEN, B. A. & ERB, H. N. (2007) Microalbuminuria and comparison of serologic testing for exposure to Borrelia burgdorferi in nonclinical Labrador and Golden Retrievers. Journal of Veterinary Diagnostic Investigation 19, 294-297
7. GOOSSENS, H. A., VAN DEN BOGAARD, A. E & NOHLMANS, M. K. (2001) Dogs as sentinels for human Lyme borreliosis in The Netherlands. Journal of Clinical Microbiology 39, 844-848
8. GREENE, C. E. & STRAUBINGER, R. K. (2006) Borreliosis. In Infectious Diseases of the Dog and the Cat. Ed C. E. Greene. Saunders Elsevier. pp 417-435
9. GUERRA, M., WALKER, E. & KITRON, U. (2000) Quantitative approach for the serodiagnosis of canine Lyme disease by the immunoblot procedure. Journal of Clinical Microbiology 38, 2628-2632
10. HAUSER, U., LEHNERT, G., LOBENTANZER, R. & WILSKE, B. (1997) Interpretation criteria for standardized Western blots for three European species of Borrelia burgdorferi sensu lato. Journal of Clinical Microbiology 35, 1433-1444
11. JACOBSON, R. H., CHANG, Y. F. & SHIN, S. J. (1996) Lyme disease: laboratory diagnosis of infected and vaccinated symptomatic dogs. Seminars in Veterinary Medicine And Surgery-Small Animal 11, 172-182
12. KRUPKA, I., PANTCHEV, N., LORENTZEN, L., WEISE, M. & STRAUBINGER, R. K. (2007) Tick-transmitted, bacterial infections in dogs: seroprevalences of Anaplasma phagocytophilum, Borrelia burgdorferi sensu lato and Ehrlichia canis in Germany. Praktische Tierarzt 88, 776-788 (In German)
13. LEVY, S., O'CONNOR, T. P., HANSCOM, J. L. & SHIELDS, P. (2002) Utility of an inoffice C6 ELISA test kit for determination of infection status of dogs naturally exposed to Borrelia burgdorferi. Veterinary Therapeutics 3, 308-315
14. LIANG, F. T., ABERER, E., CINCO, M., GERN, L., HU, C. M., LOBET, Y. N., RUSCIO, M., VOET, P. E., Jr, WEYNANTS, V. E. & PHILIPP, M. T. (2000a) Antigenic conservation of an immunodominant invariable region of the VlsE lipoprotein among European pathogenic genospecies of Borrelia burgdorferi SL. Journal of Infectious Diseases 182, 1455-1462
15. LIANG, F. T., JACOBSON, R. H., STRAUBINGER, R. K., GROOTERS, A. & PHILIPP, M. T. (2000b) Characterization of a Borrelia burgdorferi VlsE invariable region useful in canine Lyme disease serodiagnosis by enzyme-linked immunosorbent assay. Journal of Clinical Microbiology 38, 4160-4166
16. LIANG, F. T., STEERE, A. C., MARQUES, A. R., JOHNSON, B. J., MILLER, J. N. & PHILIPP, M. T. (1999) Sensitive and specific serodiagnosis of Lyme disease by enzymelinked immunosorbent assay with a peptide based on an immunodominant conserved region of Borrelia burgdorferi vlsE. Journal of Clinical Microbiology 37, 3990-3996
17. LINDENMAYER, J. M., MARSHALL, D. & ONDERDONK, A. B. (1991) Dogs as sentinels for Lyme disease in Massachusetts. American Journal of Public Health 81, 1448-1455
18. LITTMAN, M. P., GOLDSTEIN, R. E., LABATO, M. A., LAPPIN, M. R. &. MOORE, G. E. (2006) ACVIM small animal consensus statement on Lyme disease in dogs: diagnosis, treatment, and prevention. Journal of Veterinary Internal Medicine 20, 422-434
19. MAGNARELLI, L. A., IJDO, J. W., PADULA, S. J., FLAVELL, R. A. & FIKRIG, E. (2000) Serologic diagnosis of Lyme borreliosis by using enzyme-linked immunosorbent assays with recombinant antigens. Journal of Clinical Microbiology 38, 1735-1739
20. MARQUES, A. R., MARTIN, D. S. & PHILIPP, M. T. (2002) Evaluation of the C6 peptide enzyme-linked immunosorbent assay for individuals vaccinated with the recombinant OspA vaccine. Journal of Clinical Microbiology 40, 2591-2593
21. O'CONNOR, T. P., ESTY, K. J., HANSCOM, J. L., SHIELDS, P. & PHILIPP, M. T. (2004) Dogs vaccinated with common Lyme disease vaccines do not respond to IR6, the conserved immunodominant region of the VlsE surface protein of Borrelia burgdorferi. Clinical and Diagnostic Laboratory Immunology 11, 458-462
22. PHILIPP, M. T., BOWERS, L. C., FAWCETT, P. T., JACOBS, M. B., LIANG, F. T., MARQUES, A. R., MITCHELL, P. D., PURCELL, J. E., RATTERREE, M. S. & STRAUBINGER, R. K. (2001) Antibody response to IR6, a conserved immunodominant region of the VlsE lipoprotein, wanes rapidly after antibiotic treatment of Borrelia burgdorferi infection in experimental animals and in humans. Journal of Infectious Diseases 184, 870-878
23. ROBERTSON, J., GUY, E., ANDREWS, N., WILSKE, B., ANDA, P., GRANSTROM, M., HAUSER, U., MOOSMANN, Y., SAMBRI, V., SCHELLEKENS, J., STANEK, G. & GRAY, J. (2000) A European multicenter study of immunoblotting in serodiagnosis of lyme borreliosis. Journal of Clinical Microbiology 38, 2097-2102
24. RYFFEL, K., PETER, O., RUTTI, B., SUARD, A. & DAYER, E. (1999) Scored antibody reactivity determined by immunoblotting shows an association between clinical manifestations and the presence of Borrelia burgdorferi sensu stricto, B garinii, B afzelli, and B valaisiana in humans. Journal of Clinical Microbiology 37, 4086-4092
25. SPECK, S., REINER, B., STREICH, W. J., REUSCH, C. & WITTENBRINK, M. M. (2007) Canine borreliosis: a laboratory diagnostic trial. Veterinary Microbiology 120, 132-141
26. STANEK, G. & STRLE, F. (2003) Lyme borreliosis. Lancet 362, 1639-1647
27. STEERE, A. C. (2001) Lyme disease. New England Journal of Medicine 345, 115-125
28. STRAUBINGER, R. K., STRAUBINGER, A. F., SUMMERS, B. A. & JACOBSON, R. H. (2000) Status of Borrelia burgdorferi infection after antibiotic treatment and the effects of corticosteroids: An experimental study. Journal of Infectious Diseases 181, 1069-1081
29. WITTENBRINK, M. M., FAILING, K. & KRAUSS, H. (1996) Enzyme-linked immunosorbent assay and immunoblot analysis for detection of antibodies to Borrelia burgdorferi in dogs. The impact of serum absorption with homologous and heterologous bacteria. Veterinary Microbiology 48, 257-268