Scored antibody reactivity determined by immunoblotting shows an association between clinical manifestations and presence of Borrelia burgdorferi sensu stricto, B. garinii, B. afzelii, and B. valaisiana in humans

Journal of Clinical Microbiology

Volumn 37, Issue 12, 1999, Pages 4086-4092

  Ryffel, Karine ^a   Péter, Olivier ^a   Rutti, Bernard ^b   Suard, André ^c   Dayer, Eric ^a  

^a Institut Central des Hopitaux Valaisans   (Switzerland)

^b UNIVERSITY OF NEUCHÂTEL   (Switzerland)

^c NONE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACRODERMATITIS; ANTIBODY RESPONSE; ARTICLE; BACTERIAL VIRULENCE; BORRELIA AFZELII; BORRELIA BURGDORFERI; BORRELIA GARINII; BORRELIA INFECTION; HOST RESISTANCE; HUMAN; INFECTION RESISTANCE; LYME DISEASE; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE;

BACTERIA (MICROORGANISMS); BORRELIA; BORRELIA AFZELII; BORRELIA BURGDORFERI; BORRELIA GARINII; BORRELIA VALAISIANA;

EID: 0344718084     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/jcm.37.12.4086-4092.1999     Document Type: Article

References (51)

1. Altpeter, E. S., and C. Meier. 1992. Epidemiologische Aspekte der neurolo gischen Komplikationen der Lyme-Borreliose in der Schweiz. Schweiz. Med. Wochenschr. 122:22-26.
2. Anthonissen, F. M., M. De Kesel, P. P. Hoet, and G. H. Bigaignon. 1994. Evidence for the involvement of different genospecies of Borrelia in the clinical outcome of Lyme disease in Belgium. Res. Microbiol. 145:327-331.
3. Assous, M. V., D. Postic, G. Paul, P. Nevot, and G. Baranton. 1993. Western blot analysis of sera from Lyme borreliosis patients according to the genomic species of the Borrelia strains used as antigens. Eur. J. Clin. Microbiol. Infect. Dis. 12:261-268.
4. Baranton, G., D. Postic, I. Saint-Girons, P. Boerlin, J. C. Piffaretti, M. Assous, and P. A. D. Grimont. 1992. Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis. Int. J. Syst. Bacteriol. 42:378-383.
5. Bemasconi, M. V., C. Valsangiacomo, T. Balmelli, O. Péter, and J. C. Piffaretti. 1997. Tick zoonoses in the southern part of Switzerland (Canton Ticino): occurrence of Borrelia burgdorferi sensu lato and Rickettsia sp. Eur. J. Epidemiol. 13:209-215.
6. Bruckbauer, H. R., V. Preac-Mursic, R. Fuchs, and B. Wilske. 1992. Cross-reactive proteins of Borrelia burgdorferi. Eur. J. Clin. Microbiol. Infect Dis. 11:224-232.
7. Bunikis, J., C. J. Luke, E. Bunikiene, S. Bergstrom, and A. G. Barbour. 1998. A surface-exposed region of a novel outer membrane protein (P66) of Borrelia spp. is variable in size and sequence. J. Bacteriol. 180:1618-1623.
8. Bunikis, J., B. Olsen, G. Westman, and S. Bergstrom. 1995. Variable serum immunoglobulin responses against different Borrelia burgdorferi sensu lato species in a population at risk for and patients with Lyme disease. J. Clin. Microbiol. 33:1473-1478.
9. Canica, M. M., F. Nato, L. du Merle, J. C. Mazie, G. Baranton, and D. Postic. 1993. Monoclonal antibodies for identification of Borrelia afzelii sp. nov. associated with late cutaneous manifestations of Lyme borreliosis. Scand. J. Infect. Dis. 25:441-448.
10. Cinco, M., R. Murgia, M. Ruscio, and B. Andriolo. 1996. IgM and IgG significant reactivity to Borrelia burgdorferi sensu stricto, Borrelia garinii and Borrelia afzelii among Italian patients affected by Lyme arthritis or neurobor reliosis. FEMS. Immunol. Med. Microbiol. 14:159-166.
11. Demaerschalck, I., A. B. Messaoud, M. de Kesel, B. Hoyois, Y. Lobet, P. Hoet, G. Bigaignon, A. Bollen, and E. Godfroid. 1995. Simultaneous presence of different Borrelia burgdorferi genospecies in biological fluids of Lyme disease patients. J. Clin. Microbiol. 33:602-608.
12. Dressler, F., J. A. Whalen, B. N. Reinhardt, and A. C. Steere. 1993. Western blotting in the serodiagnosis of Lyme disease. J. Infect. Dis. 167:392-400.
13. Dunand, V., A. G. Bretz, A. Suard, G. Praz, E. Dayer, and O. Péter. 1998. Acrodermatitis chronica atrophicans and serologic confirmation of infection due to Borrelia afzelii and/or Borrelia garinii by immunoblot. Clin. Microbiol. Infect. 4:159-163.
14. Eiffert, H., A. Ohlenbusch, H.-J. Christen, R. Thompsen, A. Spielman, and F.-R. Matuschka. 1995. Nondifferentiation between Lyme disease spiro chetes from vector ticks and human cerebrospinal fluid. J. Infect. Dis. 171: 476-479.
15. Eiffert, H., A. Karsten, R. Thompsen, and H.-J. Christen. 1998. Characterization of Borrelia burgdorferi strains in Lyme arthritis. Scand. J. Infect. Dis. 30:265-268.
16. Engstrom, S. M., E. Shoop, and R. C. Johnson. 1995. Immunoblot interpretation criteria for serodiagnosis of early Lyme disease. J. Clin. Microbiol. 33:419-427.
17. Gern, L. Personal communication.
18. Gray, J. S., O. Kahl, J. N. Robertson, M. Daniel, A. Estrada-Pena, G. Gettinby, T. G. Jaenson, P. Jensen, F. Jongejan, F. Korenberg, K. Kurten bach, and P. Zeman. 1998. Lyme borreliosis habitat assessment. Zentralbl. Bakteriol. 287:211-228.
19. Humair, P. F., D. Postic, R. Wallich, and L. Gern. 1998. An avian reservoir (Turdus merula) of the Lyme borreliosis spirochetes. Zentbl. Bakteriol. Para sitenkd. Infektkrankh. Hyg. Abt. 1 Orig. 287:521-538.
20. Isogai, E., S. Tanaka, I. S. Braga III, C. Itakura, H. Isogai, K. Kimura, and N. Fujii. 1994. Experimental Borrelia garinii infection of Japanese quail. Infect. Immun. 62:3580-3582.
21. Kalish, R. A., J. M. Leong, and A. C. Steere. 1993. Association of treatment- resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi. Infect. Immun. 61:2774-2779.
22. Karlsson, M. 1991. Antibody response against autologous and heterologous isolates of Borrelia burgdorferi in four patients with Lyme neuroborreliosis. Eur. J. Clin. Microbiol. Infect. Dis. 10:742-745.
23. Karlsson, M., I. Mollegard, G. Stiernstedt, and B. Wretlind. 1989. Comparison of Western blot and enzyme-linked immunosorbent assay for diagnosis of Lyme borreliosis. Eur. J. Clin. Microbiol. Infect. Dis. 8:871-877.
24. Kirstein, F., S. Rijpkema, M. Molkenboer, and J. S. Gray. 1997. The distribution and prevalence of B. burgdorferi genomospecies in Ixodes ricinus ticks in Ireland. Eur. J. Epidemiol. 13:67-72.
25. Le Fleche, A., D. Postic, K. Girardet, O. Péter, and G. Baranton. 1997. Characterization of Borrelia lusitaniae sp. nov. by 16S ribosomal DNA. Int. J. Syst. Bacteriol. 47:921-925.
26. Luft, B. J., P. D. Gorevic, W. Jiang, P. Munoz, and R. J. Dattwyler. 1991. Immunologic and structural characterization of the dominant 66- to 73-kDa antigens of Borrelia burgdorferi. J. Immunol. 146:2776-2782.
27. Ma, B., B. Christen, D. Leung, and C. Vigo-Pelfrey. 1992. Serodiagnosis of Lyme borreliosis by Western immunoblot: reactivity of various significant antibodies against Borrelia burgdorferi. J. Clin. Microbiol. 30:370-376.
28. Magnarelli, L. A., J. F. Anderson, R. C. Johnson, R. B. Nadelman, and G. P. Wormser. 1994. Comparison of different strains of Borrelia burgdorferi sensulato used as antigens in enzyme-linked immunosorbent assays. J. Clin. Microbiol. 32:1154-1158.
29. Mansy, F., B. Hoyois, M. J. de Vos, A. van Elsen A. Bollen, and E. Godfroid. 1996. Colorimetric solid-phase capture hybridization assay for detection of amplified Borrelia burgdorferi DNA. BioTechniques 21:122-125.
30. Nakao, M., K. Miyamoto, and M. Fukunaga. 1994. Lyme disease spirochetes in Japan: enzootic transmission cycles in birds, rodents, and Ixodes persulcatus ticks. J. Infect. Dis. 170:878-882.
31. Norman, G. L., J. M. Antig, G. Bigaignon, and W. R. Hogrefe. 1996. Serodiagnosis of Lyme borreliosis by Borrelia burgdorferi sensu stricto, B. garinii, and B. afzelii Western blots (immunoblots). J. Clin. Microbiol. 34:1732-1738.
32. Olsen, B., T. G. Jaenson, L. Noppa, J. Bunikis, and S. Bergstrom. 1993. A Lyme borreliosis cycle in seabirds and Ixodes uriae ticks. Nature 362:340-342.
33. Péter, O., A.-G. Bretz, D. Postic, and E. Dayer. 1997. Association of distinct species of Borrelia burgdorferi sensu lato with neuroborreliosis in Switzerland. Clin. Microbiol. Infect. 3:423-431.
34. Péter, O., and A. G. Bretz. 1992. Polymorphism of outer surface proteins of Borrelia burgdorferi as a tool for classification. Zentbl. Bakteriol. Parasitenkd. Infektkrankh. Hyg. Abt. 1 Orig. 277:28-33.
35. Péter, O., A. G. Bretz, and D. Bee. 1995. Occurrence of different genospecies of Borrelia burgdorferi sensu lato in Ixodid ticks of Valais, Switzerland. Eur. J. Epidemiol. 11:463-467.
36. Postic, D., M. V. Assous, P. A. Grimont, and G. Baranton. 1994. Diversity of Borrelia burgdorferi sensu lato evidenced by restriction fragment length polymorphism of rrf (5S)-rrl (23S) intergenic spacer amplicons. Int. J. Syst. Bacteriol. 44:743-752.
37. Rijpkema, S. G., R. G. Herbes, N. Verbeek-De Kruif, and J. F. Schellekens. 1996. Detection of four species of Borrelia burgdorferi sensu lato in Ixodes ricinus ticks collected from roe deer (Capreolus capreolus) in The Netherlands. Epidemiol. Infect. 117:563-566.
38. Rijpkema, S. G. T., D. Tazelaar, M. Molkenboer, G. Noordhoek, G. Plantinga, L. Schools, and J. Schellekens. 1997. Detection of Borrelia afzelii, Borrelia burgdorferi sensu stricto, Borrelia garinii and group VS116 by PCR in skin biopsies of patients with erythema migrans and acrodermatitis chronica atrophicans. Clin. Microbiol. Infect. 3:109-116.
39. Ryffel, K., O. Péter, L. Binet. and E. Dayer. 1998. Interpretation of immunoblots for Lyme borreliosis using a semiquantitative approach. Clin. Microbiol. Infect. 4:205-212.
40. Saint Girons, I., L. Gern, J. S. Gray, E. C. Guy, E. Korenberg, P. A. Nuttall, S. G. T. Rijpkema, A. Schönberg, G. Stanek, and D. Postic. 1998. Identification of Borrelia burgdorferi sensu lato species in Europe. Zentbl. Bakteriol. Parasitenkd. Infektkrankh. Hyg. Abt. 1 Orig. 287:190-195.
41. Steere, A. C. 1989. Lyme disease. N. Engl. J. Med. 321:586-596.
42. Valsangiacomo, C. T. Balmelli, and J. C. Piffaretti. 1997. A phylogenetic analysis of Borrelia burgdorferi sensu lato based on sequence information from the hbb gene, coding for a histone-like protein. Int. J. Syst. Bacteriol. 47:1-10.
43. van Dam, A. P., H. Kuiper, K. Vos, A. Widdjojokusumo, B. M. de Jongh, S. Spanjaard, A. C. T. Ramselaar, M. D. Kramer, and J. Dankert. 1993. Different genospecies of Borrelia burgdorferi are associated with distinct clinical manifestations of Lyme borreliosis. Clin. Infect. Dis. 17:708-717.
44. Vasiliu, V., P. Herzer, D. Rossler, G. Lehnert, and B. Wilske. 1998. Heterogeneity of Borrelia burgdorferi sensu lato demonstrated by an ospA-type- specific PCR in synovial fluid from patients with Lyme arthritis. Med. Microbiol. Immunol. (Berlin) 187:97-102.
45. Wang, G., A. P. van Dam, A. Le Flèche, D. Postic, O. Péter, G. Baranton, R. de Boer, L. Spanjaard, and J. Dankert. 1997. Genetic and phenotypic analysis of Borrelia valaisiana sp. nov. (Borrelia genomic groups VS116 and M19). Int. J. Syst. Bacteriol. 47:926-932.
46. Wilske, B., U. Busch, H. Eiffert, V. Fingerle, H. W. Pfister, D. Rössler, and V. Preac-Mursic. 1996. Diversity of OspA and OspC among cerebrospinal fluid isolates of Borrelia burgdorferi sensu lato from patients with neuroborreliosis in Germany. Med. Microbiol. Immunol. (Berlin) 184:195-201.
47. Wilske, B., V. Fingerle, V. Preac-Mursic, S. Jauris-Heipke, A. Hofmann, H. Loy, H. W. Pfister, D. Rössler, and E. Soutschek. 1994. Immunoblot using recombinant antigens derived from different genospecies of Borrelia burg dorferi sensu lato. Med. Microbiol. Immunol. (Berlin) 183:43-59.
48. Wilske, B., V. Preac-Mursic, U. B. Göbel, B. Graf, S. Jauris, E. Soutschek, E. Schwab, and G. Zumstein. 1993. An OspA serotyping system for Borrelia burgdorferi based on reactivity with monoclonal antibodies and OspA sequence analysis. J. Clin. Microbiol. 31:340-350.
49. Wilske, B., V. Preac-Mursic, S. Jauris, A. Hofmann, I. Pradel, E. Soutschek, E. Schwab, G. Will, and G. Wanner. 1993. Immunological and molecular polymorphisms of OspC, an immunodominant major outer surface protein of Borrelia burgdorferi. Infect. Immun. 61:2182-2191.
50. Wilske, B., V. Preac-Mursic, G. Schierz, and K. V. Busch. 1986. Immunochemical and immunological analysis of European Borrelia burgdorferi strains. Zentbl. Bakteriol Mikrobiol. Hyg. Reihe A 263:92-102.
51. Zoller, L., S. Burkard, and H. Schafer. 1991. Validity of Western immunoblot band patterns in the serodiagnosis of Lyme borreliosis. J. Clin. Microbiol. 29:174-182.