Characterization of a Borrelia burgdorferi VlsE invariable region useful in canine lyme disease serodiagnosis by enzyme-linked immunosorbent assay

Journal of Clinical Microbiology

Volumn 38, Issue 11, 2000, Pages 4160-4166

  Liang, F T ^a   Jacobson, R H ^a   Straubinger, R K ^a   Grooters, A ^a   Philipp, M T ^a  

^a TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BACTERIAL ANTIGEN; BACTERIUM LYSATE; EPITOPE; MEMBRANE PROTEIN; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BACTERIAL OUTER MEMBRANE; BACTERIUM CULTURE; BORRELIA BURGDORFERI; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DOG; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOBLOTTING; IMMUNOGENICITY; LYME DISEASE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; SERODIAGNOSIS; SERUM; TICK; VACCINATION; VETERINARY MEDICINE;

ACARI; ANIMALIA; BACTERIA (MICROORGANISMS); BORRELIA; BORRELIA BURGDORFERI; CANIS FAMILIARIS; SPIROCHAETALES;

EID: 0034462227     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/jcm.38.11.4160-4166.2000     Document Type: Article

References (23)

1. Experimental Lyme disease in dogs produces arthritis and persistent infection
2. A Borrelia genus-specific monoclonal antibody binds to a flagellar epitope
3. B-cell epitopes: Fact and fiction
4. Immunogenicity and antigen structure
5. Immunogenicity and efficacy study of a commercial Borrelia burgdorferi bacterin
6. Greater risk of Borrelia burgdorferi infection in dogs than in people
7. Immunochemical characterization of and isolation of the gene for a Borrelia burgdorferi immunodominant 60-kilodalton antigen common to a wide range of bacteria
8. Conservation and heterogeneity of vlsE among human and tick isolates of Borrelia burgdorferi
9. Validation of serological assays for diagnosis of infectious diseases
10. Genetic and immunological analyses of Vls (VMP-like sequences) of Borrelia burgdorferi
11. Human antibody responses to VlsE antigenic variable protein of Borrelia burgdorferi
12. An immunodominant conserved region within the variable domain of VlsE, the variable surface antigen of Borrelia burgdorferi
13. Sensitive and specific serodiagnosis of Lyme disease by ELISA with a peptide based on an immunodominant conserved region of Borrelia burgdorferi VlsE
14. Analysis of antibody response to invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi
15. Epitope mapping of the immunodominant invariable region of VlsE, the variable surface antigen of Borrelia burgdorferi
16. Cryptic and exposed invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi
17. Antigenic conservation of an immunodominant invariable region of the VlsE lipoprotein among European pathogenic genospecies of Borrelia burgdorferi s1
18. Dogs as sentinels for Lyme disease in Massachusetts
19. Immunologic and structural characterization of the dominant 66- to 73-kDa antigens of Borrelia burgdorferi
20. Cross-reactivity between Borrelia burgdorferi and other spirochetes affects specificity of serotests for detection of antibodies to the Lyme disease agent in dogs
21. Status of Borrelia burgdorferi infection after antibiotic treatment and the effects of corticosteroids: An experimental study
22. Antigenic variation in Lyme disease Borreliae by promiscuous recombination of VMP-like sequence cassettes