The reaction mechanism of phenylethanolamine N-methyltransferase: A density functional theory study

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1794, Issue 12, 2009, Pages 1831-1837

  Georgieva, Polina ^a   Wu, Qian ^b   McLeish, Michael J ^b,c   Himo, Fahmi ^a,d  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^b UNIVERSITY OF MICHIGAN   (United States)

^c INDIANA UNIVERSITY   (United States)

^d STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Enzyme mechanism; Methyl transfer; Mutagenesis; pKa; Quantum chemistry

Indexed keywords

ADRENALIN; CATECHOL METHYLTRANSFERASE; CATECHOLAMINE; GLUTAMIC ACID; GLYCINE METHYLTRANSFERASE; GUANIDINOACETATE METHYLTRANSFERASE; METHYLTRANSFERASE; NORADRENALIN; PHENYLETHANOLAMINE N METHYLTRANSFERASE; S ADENOSYLMETHIONINE;

ARTICLE; CATALYSIS; CATECHOLAMINE SYNTHESIS; DENSITY FUNCTIONAL THEORY; ENZYME ACTIVE SITE; GEOMETRY; HUMAN; MUTAGENESIS; PRIORITY JOURNAL; REACTION ANALYSIS; X RAY;

EID: 73049101676     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2009.08.022     Document Type: Article

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