Triptolide inhibits the proliferation of immortalized HT22 hippocampal cells via persistent activation of extracellular signal-regulated kinase-1/2 by down-regulating mitogen-activated protein kinase phosphatase-1 expression

Journal of Korean Neurosurgical Society

Volumn 46, Issue 4, 2009, Pages 389-396

  Hee, Sang Koo ^a   Sung, Don Kang ^a   Ju, Hwan Lee ^a   Kim, Nam Ho ^b   Chung, Hun Taeg ^c   Pae, Hyun Ock ^a  

^a Wonkwang University School of Medicine   (South Korea)

^b Wonkwang University Hospital   (South Korea)

^c University of Ulsan College of Medicine   (South Korea)

Author keywords

Extracellular signal regulated kinase 1 2; HT22 hippocampal cell; Mitogen activated protein kinase; Mitogen activated protein kinase phosphatase 1; Proliferation; Triptolide

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; SMALL INTERFERING RNA; TRIPTOLIDE; VANADIC ACID;

ANIMAL CELL; ANIMAL CELL CULTURE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; ENZYME ACTIVATION; GENETIC TRANSFECTION; GROWTH INHIBITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

EID: 72949123249     PISSN: 20053711     EISSN: 15987876     Source Type: Journal    
DOI: 10.3340/jkns.2009.46.4.389     Document Type: Article

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