A germline knowledge based computational approach for determining antibody complementarity determining regions

Molecular Immunology

Volumn 47, Issue 4, 2010, Pages 694-700

  Zhao, Shanrong ^a   Lu, Jin ^b  

^a Centocor Discovery Research   (United States)

^b CENTOCOR INC   (United States)

Author keywords

Algorithm; CDR definition; CDR delimitation; Chothia; Complementarity determining regions (CDRs); Framework regions (FRs); Germline; IMGT; JAVA; Kabat; Somatic deletions; Somatic insertions

Indexed keywords

ALGORITHM; AMINO ACID SEQUENCE; ANTIBODY ENGINEERING; ARTICLE; BIOINFORMATICS; COMPLEMENTARITY DETERMINING REGION; GENE DELETION; GENE INSERTION; GENE LIBRARY; GENE SEQUENCE; GENETIC VARIABILITY; GERM LINE; KNOWLEDGE BASE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SOMATIC HYPERMUTATION;

ALGORITHMS; AMINO ACID SEQUENCE; COMPLEMENTARITY DETERMINING REGIONS; COMPUTATIONAL BIOLOGY; GERM CELLS; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; SEQUENCE DELETION;

EID: 72949120359     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.10.028     Document Type: Article

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