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Volumn 75, Issue 1, 2010, Pages 76-91

Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM; CEFOTAXIME; CEFTAZIDIME; CHLORAMPHENICOL; CIPROFLOXACIN; GLUTATHIONE PEROXIDASE; HYDROPEROXIDE; TYROSINE;

EID: 72949110182     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2009.06955.x     Document Type: Article
Times cited : (65)

References (60)
  • 1
    • 3242813728 scopus 로고    scopus 로고
    • The homogentisate pathway: A central catabolic pathway involved in the degradation of l-phenylalanine, l-tyrosine, and 3-hydroxyphenylacetate in Pseudomonas putida
    • Arias-Barrau, E., Olivera, E.R., Luengo, J.M., Fernández, C., Galán, B., García, J.L., et al. (2004) The homogentisate pathway: a central catabolic pathway involved in the degradation of l-phenylalanine, l-tyrosine, and 3-hydroxyphenylacetate in Pseudomonas putida. J Bacteriol 186 : 5062 5077.
    • (2004) J Bacteriol , vol.186 , pp. 5062-5077
    • Arias-Barrau, E.1    Olivera, E.R.2    Luengo, J.M.3    Fernández, C.4    Galán, B.5    García, J.L.6
  • 2
    • 33750230997 scopus 로고    scopus 로고
    • An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus
    • Chen, P.R., Bae, T., Williams, W.A., Duguid, E.M., Rice, P.A., Schneewind, O. He, C. (2006) An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus. Nat Chem Biol 2 : 591 595.
    • (2006) Nat Chem Biol , vol.2 , pp. 591-595
    • Chen, P.R.1    Bae, T.2    Williams, W.A.3    Duguid, E.M.4    Rice, P.A.5    Schneewind, O.6    He, C.7
  • 3
    • 58149105545 scopus 로고    scopus 로고
    • A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus
    • Chen, P.R., Nishida, S., Poor, C.B., Cheng, A., Bae, T., Kuechenmeister, L., et al. (2008a) A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus. Mol Microbiol 71 : 198 211.
    • (2008) Mol Microbiol , vol.71 , pp. 198-211
    • Chen, P.R.1    Nishida, S.2    Poor, C.B.3    Cheng, A.4    Bae, T.5    Kuechenmeister, L.6
  • 4
    • 51649131425 scopus 로고    scopus 로고
    • The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism
    • Chen, H., Hu, J., Chen, P.R., Lan, L., Li, Z., Hicks, L.M., et al. (2008b) The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism. Proc Natl Acad Sci USA 105 : 13586 13591.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13586-13591
    • Chen, H.1    Hu, J.2    Chen, P.R.3    Lan, L.4    Li, Z.5    Hicks, L.M.6
  • 5
    • 31344471227 scopus 로고    scopus 로고
    • OhrR and ohr are the primary sensor/regulator and protective genes against organic hydroperoxide stress in Agrobacterium tumefaciens
    • Chuchue, T., Tanboon, W., Prapagdee, B., Dubbs, J.M., Vattanaviboon, P. Mongkolsuk, S. (2006) ohrR and ohr are the primary sensor/regulator and protective genes against organic hydroperoxide stress in Agrobacterium tumefaciens. J Bacteriol 188 : 842 851.
    • (2006) J Bacteriol , vol.188 , pp. 842-851
    • Chuchue, T.1    Tanboon, W.2    Prapagdee, B.3    Dubbs, J.M.4    Vattanaviboon, P.5    Mongkolsuk, S.6
  • 7
    • 0020851762 scopus 로고
    • Nosocomial infections due to Pseudomonas aeruginosa: Review of recent trends
    • Cross, A., Allen, J.R., Burke, J., Ducel, G., Harris, A., John, J., et al. (1983) Nosocomial infections due to Pseudomonas aeruginosa: review of recent trends. Rev Infect Dis 5 : S837 S845.
    • (1983) Rev Infect Dis , vol.5
    • Cross, A.1    Allen, J.R.2    Burke, J.3    Ducel, G.4    Harris, A.5    John, J.6
  • 8
    • 33747082622 scopus 로고    scopus 로고
    • The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa
    • Dietrich, L.E., Price-Whelan, A., Petersen, A., Whiteley, M. Newman, D.K. (2006) The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa. Mol Microbiol 61 : 1308 1321.
    • (2006) Mol Microbiol , vol.61 , pp. 1308-1321
    • Dietrich, L.E.1    Price-Whelan, A.2    Petersen, A.3    Whiteley, M.4    Newman, D.K.5
  • 9
    • 50649098819 scopus 로고    scopus 로고
    • Redox-active antibiotics control gene expression and community behavior in divergent bacteria
    • Dietrich, L.E., Teal, T.K., Price-Whelan, A. Newman, D.K. (2009) Redox-active antibiotics control gene expression and community behavior in divergent bacteria. Science 321 : 1203 1206.
    • (2009) Science , vol.321 , pp. 1203-1206
    • Dietrich, L.E.1    Teal, T.K.2    Price-Whelan, A.3    Newman, D.K.4
  • 10
    • 0034971954 scopus 로고    scopus 로고
    • OhrR is a repressor of ohrA, a key organic hydroperoxide resistance determinant in Bacillus subtilis
    • Fuangthong, M., Atichartpongkul, S., Mongkolsuk, S. Helmann, J.D. (2001) OhrR is a repressor of ohrA, a key organic hydroperoxide resistance determinant in Bacillus subtilis. J Bacteriol 183 : 4134 4141.
    • (2001) J Bacteriol , vol.183 , pp. 4134-4141
    • Fuangthong, M.1    Atichartpongkul, S.2    Mongkolsuk, S.3    Helmann, J.D.4
  • 11
    • 58149389286 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa-Candida albicans interactions: Localization and fungal toxicity of a phenazine derivative
    • Gibson, J., Sood, A. Hogan, D.A. (2009) Pseudomonas aeruginosa-Candida albicans interactions: localization and fungal toxicity of a phenazine derivative. Appl Environ Microbiol 75 : 504 513.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 504-513
    • Gibson, J.1    Sood, A.2    Hogan, D.A.3
  • 12
    • 0022797349 scopus 로고
    • Pseudomonas aeruginosa and cystic fibrosis: Unusual bacterial adaptation and pathogenesis
    • Govan, J.R.W. Harris, G.S. (1986) Pseudomonas aeruginosa and cystic fibrosis: unusual bacterial adaptation and pathogenesis. Microbiol Sci 3 : 302 308.
    • (1986) Microbiol Sci , vol.3 , pp. 302-308
    • Govan, J.R.W.1    Harris, G.S.2
  • 13
    • 0024811787 scopus 로고
    • Bacterial adaptation to oxidative stress: Implications for pathogenesis and interaction with phagocytic cells
    • Hassett, D.J. Cohen, M.S. (1989) Bacterial adaptation to oxidative stress: implications for pathogenesis and interaction with phagocytic cells. FASEB J 3 : 2574 2582.
    • (1989) FASEB J , vol.3 , pp. 2574-2582
    • Hassett, D.J.1    Cohen, M.S.2
  • 14
    • 0033451899 scopus 로고    scopus 로고
    • Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide
    • Hassett, D.J., Ma, J.F., Elkins, J.G., McDermott, T.R., Ochsner, U.A., West, S.E., et al. (1999) Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide. Mol Microbiol 34 : 1082 1093.
    • (1999) Mol Microbiol , vol.34 , pp. 1082-1093
    • Hassett, D.J.1    Ma, J.F.2    Elkins, J.G.3    McDermott, T.R.4    Ochsner, U.A.5    West, S.E.6
  • 15
    • 0032575051 scopus 로고    scopus 로고
    • A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: Application for isolation of unmarked Pseudomonas aeruginosa mutants
    • Hoang, T.T., Karkhoff-Schweizer, R.R., Kutchma, A.J. Schweizer, H.P. (1998) A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants. Gene 212 : 77 86.
    • (1998) Gene , vol.212 , pp. 77-86
    • Hoang, T.T.1    Karkhoff-Schweizer, R.R.2    Kutchma, A.J.3    Schweizer, H.P.4
  • 17
    • 50649117912 scopus 로고    scopus 로고
    • Cellular defenses against superoxide and hydrogen peroxide
    • Imlay, J.A. (2008) Cellular defenses against superoxide and hydrogen peroxide. Annu Rev Biochem 77 : 755 776.
    • (2008) Annu Rev Biochem , vol.77 , pp. 755-776
    • Imlay, J.A.1
  • 19
    • 0028285881 scopus 로고
    • Deletion and transposon mutagenesis and sequence analysis of the pRO1600 OriR region found in the broad-host range plasmids of the pQF series
    • Jansons, I., Touchie, G., Sharp, R., Almquist, K., Farina, M., Lam, J.S. Kropinski, A.M. (1994) Deletion and transposon mutagenesis and sequence analysis of the pRO1600 OriR region found in the broad-host range plasmids of the pQF series. Plasmid 31 : 265 274.
    • (1994) Plasmid , vol.31 , pp. 265-274
    • Jansons, I.1    Touchie, G.2    Sharp, R.3    Almquist, K.4    Farina, M.5    Lam, J.S.6    Kropinski, A.M.7
  • 20
    • 38049121021 scopus 로고    scopus 로고
    • Characterization of a homogentisate dioxygenase mutant in Pseudomonas chlororaphis O6
    • Kang, B.R., Han, S.H., Cho, S.M., Anderson, A.J., Kim, I.S., Park, S.K. Kim, Y.C. (2008) Characterization of a homogentisate dioxygenase mutant in Pseudomonas chlororaphis O6. Curr Microbiol 56 : 145 149.
    • (2008) Curr Microbiol , vol.56 , pp. 145-149
    • Kang, B.R.1    Han, S.H.2    Cho, S.M.3    Anderson, A.J.4    Kim, I.S.5    Park, S.K.6    Kim, Y.C.7
  • 21
    • 17644426975 scopus 로고    scopus 로고
    • Novel roles of ohrR-ohr in Xanthomonas sensing, metabolism, and physiological adaptive response to lipid hydroperoxide
    • Klomsiri, C., Panmanee, W., Dharmsthiti, S., Vattanaviboon, P. Mongkolsuk, S. (2005) Novel roles of ohrR-ohr in Xanthomonas sensing, metabolism, and physiological adaptive response to lipid hydroperoxide. J Bacteriol 187 : 3277 3281.
    • (2005) J Bacteriol , vol.187 , pp. 3277-3281
    • Klomsiri, C.1    Panmanee, W.2    Dharmsthiti, S.3    Vattanaviboon, P.4    Mongkolsuk, S.5
  • 22
    • 14944340675 scopus 로고    scopus 로고
    • Activation of SoxR-dependent transcription in Pseudomonas aeruginosa
    • Kobayashi, K. Tagawa, S. (2004) Activation of SoxR-dependent transcription in Pseudomonas aeruginosa. J Biochem 136 : 607 615.
    • (2004) J Biochem , vol.136 , pp. 607-615
    • Kobayashi, K.1    Tagawa, S.2
  • 23
    • 3042548715 scopus 로고    scopus 로고
    • Longitudinal study of oxidative status in 312 cystic fibrosis patients in stable state and during bronchial exacerbation
    • Lagrange-Puget, M., Durieu, I., Ecochard, R., Abbas-Chorfa, F., Drai, J., Steghens, J.P., et al. (2004) Longitudinal study of oxidative status in 312 cystic fibrosis patients in stable state and during bronchial exacerbation. Pediatr Pulmonol 38 : 43 49.
    • (2004) Pediatr Pulmonol , vol.38 , pp. 43-49
    • Lagrange-Puget, M.1    Durieu, I.2    Ecochard, R.3    Abbas-Chorfa, F.4    Drai, J.5    Steghens, J.P.6
  • 24
    • 8544275274 scopus 로고    scopus 로고
    • A novel sensor kinase-response regulator hybrid regulates type III secretion and is required for virulence in Pseudomonas aeruginosa
    • Laskowski, M.A., Osborn, E. Kazmierczak, B.I. (2004) A novel sensor kinase-response regulator hybrid regulates type III secretion and is required for virulence in Pseudomonas aeruginosa. Mol Microbiol 54 : 1090 1103.
    • (2004) Mol Microbiol , vol.54 , pp. 1090-1103
    • Laskowski, M.A.1    Osborn, E.2    Kazmierczak, B.I.3
  • 25
    • 3042550379 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa pyocyanin is critical for lung infection in mice
    • DOI 10.1128/IAI.72.7.4275-4278.2004
    • Lau, G.W., Ran, H., Kong, F., Hassett, D.J. Mavrodi, D. (2004a) Pseudomonas aeruginosa pyocyanin is critical for lung infection in mice. Infect Immun 72 : 4275 4278. (Pubitemid 38821943)
    • (2004) Infection and Immunity , vol.72 , Issue.7 , pp. 4275-4278
    • Lau, G.W.1    Ran, H.2    Kong, F.3    Hassett, D.J.4    Mavrodi, D.5
  • 26
    • 9644257146 scopus 로고    scopus 로고
    • The role of pyocyanin in Pseudomonas aeruginosa infection
    • DOI 10.1016/j.molmed.2004.10.002, PII S1471491404002606
    • Lau, G.W., Hassett, D.J., Ran, H. Kong, F. (2004b) The role of pyocyanin in Pseudomonas aeruginosa infection. Trends Mol Med 10 : 599 606. (Pubitemid 39573151)
    • (2004) Trends in Molecular Medicine , vol.10 , Issue.12 , pp. 599-606
    • Lau, G.W.1    Hassett, D.J.2    Ran, H.3    Kong, F.4
  • 27
    • 16244393355 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa OxyR is required for full virulence in rodent and insect models of infection and for resistance to human neutrophils
    • Lau, G.W., Britigan, B.E. Hassett, D.J. (2005) Pseudomonas aeruginosa OxyR is required for full virulence in rodent and insect models of infection and for resistance to human neutrophils. Infect Immun 73 : 2550 2553.
    • (2005) Infect Immun , vol.73 , pp. 2550-2553
    • Lau, G.W.1    Britigan, B.E.2    Hassett, D.J.3
  • 28
    • 33645046114 scopus 로고    scopus 로고
    • Activity of purified QscR, a Pseudomonas aeruginosa orphan quorum-sensing transcription factor
    • Lee, J.H., Lequette, Y. Greenberg, E.P. (2006) Activity of purified QscR, a Pseudomonas aeruginosa orphan quorum-sensing transcription factor. Mol Microbiol 59 : 602 609.
    • (2006) Mol Microbiol , vol.59 , pp. 602-609
    • Lee, J.H.1    Lequette, Y.2    Greenberg, E.P.3
  • 29
    • 0031921608 scopus 로고    scopus 로고
    • Cloning and characterization of the Pseudomonas aeruginosa zwf gene encoding glucose-6-phosphate dehydrogenase, an enzyme important in resistance to methyl viologen (paraquat)
    • Ma, J.F., Hager, P.W., Howell, M.L., Phibbs, P.V. Hassett, D.J. (1998) Cloning and characterization of the Pseudomonas aeruginosa zwf gene encoding glucose-6-phosphate dehydrogenase, an enzyme important in resistance to methyl viologen (paraquat). J Bacteriol 180 : 1741 1749.
    • (1998) J Bacteriol , vol.180 , pp. 1741-1749
    • Ma, J.F.1    Hager, P.W.2    Howell, M.L.3    Phibbs, P.V.4    Hassett, D.J.5
  • 30
    • 0033534534 scopus 로고    scopus 로고
    • Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model
    • Mahajan-Miklos, S., Tan, M.W., Rahme, L.G. Ausubel, F.M. (1999) Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model. Cell 96 : 47 56.
    • (1999) Cell , vol.96 , pp. 47-56
    • Mahajan-Miklos, S.1    Tan, M.W.2    Rahme, L.G.3    Ausubel, F.M.4
  • 31
    • 0035685204 scopus 로고    scopus 로고
    • Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1
    • Mavrodi, D.V., Bonsall, R.F., Delaney, S.M., Soule, M.J., Phillips, G. Thomashow, L.S. (2001) Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1. J Bacteriol 183 : 6454 6465.
    • (2001) J Bacteriol , vol.183 , pp. 6454-6465
    • Mavrodi, D.V.1    Bonsall, R.F.2    Delaney, S.M.3    Soule, M.J.4    Phillips, G.5    Thomashow, L.S.6
  • 33
    • 0031029702 scopus 로고    scopus 로고
    • Role of oxidants in microbial pathophysiology
    • Miller, R.A. Britigan, B.E. (1997) Role of oxidants in microbial pathophysiology. Clin Microbiol Rev 10 : 1 18.
    • (1997) Clin Microbiol Rev , vol.10 , pp. 1-18
    • Miller, R.A.1    Britigan, B.E.2
  • 34
    • 0036047508 scopus 로고    scopus 로고
    • Regulation of inducible peroxide stress responses
    • Mongkolsuk, S. Helmann, J.D. (2002) Regulation of inducible peroxide stress responses. Mol Microbiol 45 : 9 15.
    • (2002) Mol Microbiol , vol.45 , pp. 9-15
    • Mongkolsuk, S.1    Helmann, J.D.2
  • 35
    • 36248933266 scopus 로고    scopus 로고
    • Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR
    • Newberry, K.J., Fuangthong, M., Panmanee, W., Mongkolsuk, S. Brennan, R.G. (2007) Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR. Mol Cell 28 : 652 664.
    • (2007) Mol Cell , vol.28 , pp. 652-664
    • Newberry, K.J.1    Fuangthong, M.2    Panmanee, W.3    Mongkolsuk, S.4    Brennan, R.G.5
  • 36
    • 0033874090 scopus 로고    scopus 로고
    • Role of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF
    • Ochsner, U.A., Vasil, M.L., Alsabbagh, E., Parvatiyar, K. Hassett, D.J. (2000) Role of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF. J Bacteriol 182 : 4533 4544.
    • (2000) J Bacteriol , vol.182 , pp. 4533-4544
    • Ochsner, U.A.1    Vasil, M.L.2    Alsabbagh, E.3    Parvatiyar, K.4    Hassett, D.J.5
  • 37
    • 0346991729 scopus 로고    scopus 로고
    • Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide
    • Palma, M., DeLuca, D., Worgall, S. Quadri, L.E. (2004) Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide. J Bacteriol 186 : 248 252.
    • (2004) J Bacteriol , vol.186 , pp. 248-252
    • Palma, M.1    Deluca, D.2    Worgall, S.3    Quadri, L.E.4
  • 38
    • 17644408447 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa SoxR does not conform to the archetypal paradigm for SoxR-dependent regulation of the bacterial oxidative stress adaptive response
    • Palma, M., Zurita, J., Ferreras, J.A., Worgall, S., Larone, D.H., Shi, L., et al. (2005) Pseudomonas aeruginosa SoxR does not conform to the archetypal paradigm for SoxR-dependent regulation of the bacterial oxidative stress adaptive response. Infect Immun 73 : 2958 2966.
    • (2005) Infect Immun , vol.73 , pp. 2958-2966
    • Palma, M.1    Zurita, J.2    Ferreras, J.A.3    Worgall, S.4    Larone, D.H.5    Shi, L.6
  • 39
    • 0036032183 scopus 로고    scopus 로고
    • OhrR, a transcription repressor that senses and responds to changes in organic peroxide levels in Xanthomonas campestris pv. phaseoli
    • Panmanee, W., Vattanaviboon, P., Eiamphungporn, W., Whangsuk, W., Sallabhan, R. Mongkolsuk, S. (2002) OhrR, a transcription repressor that senses and responds to changes in organic peroxide levels in Xanthomonas campestris pv. phaseoli. Mol Microbiol 45 : 1647 1654.
    • (2002) Mol Microbiol , vol.45 , pp. 1647-1654
    • Panmanee, W.1    Vattanaviboon, P.2    Eiamphungporn, W.3    Whangsuk, W.4    Sallabhan, R.5    Mongkolsuk, S.6
  • 40
    • 32444439989 scopus 로고    scopus 로고
    • Novel organic hydroperoxide-sensing and responding mechanisms for OhrR, a major bacterial sensor and regulator of organic hydroperoxide stress
    • Panmanee, W., Vattanaviboon, P., Poole, L.B. Mongkolsuk, S. (2006) Novel organic hydroperoxide-sensing and responding mechanisms for OhrR, a major bacterial sensor and regulator of organic hydroperoxide stress. J Bacteriol 188 : 1389 1395.
    • (2006) J Bacteriol , vol.188 , pp. 1389-1395
    • Panmanee, W.1    Vattanaviboon, P.2    Poole, L.B.3    Mongkolsuk, S.4
  • 41
    • 40849097418 scopus 로고    scopus 로고
    • Discovering mechanisms of signaling-mediated cysteine oxidation
    • Poole, L.B. Nelson, K.J. (2008) Discovering mechanisms of signaling-mediated cysteine oxidation. Curr Opin Chem Biol 12 : 18 24.
    • (2008) Curr Opin Chem Biol , vol.12 , pp. 18-24
    • Poole, L.B.1    Nelson, K.J.2
  • 42
    • 33644907519 scopus 로고    scopus 로고
    • Rethinking 'secondary' metabolism: Physiological roles for phenazine antibiotics
    • Price-Whelan, A., Dietrich, L.E. Newman, D.K. (2006) Rethinking 'secondary' metabolism: physiological roles for phenazine antibiotics. Nat Chem Biol 2 : 71 78.
    • (2006) Nat Chem Biol , vol.2 , pp. 71-78
    • Price-Whelan, A.1    Dietrich, L.E.2    Newman, D.K.3
  • 43
    • 0027158657 scopus 로고
    • Versatile suicide vectors which allow direct selection for gene replacement in Gram-negative bacteria
    • Quandt, J. Hynes, M.F. (1993) Versatile suicide vectors which allow direct selection for gene replacement in Gram-negative bacteria. Gene 127 : 15 21.
    • (1993) Gene , vol.127 , pp. 15-21
    • Quandt, J.1    Hynes, M.F.2
  • 44
    • 0344198520 scopus 로고    scopus 로고
    • Human targets of Pseudomonas aeruginosa pyocyanin
    • Ran, H., Hassett, D.J. Lau, G.W. (2003) Human targets of Pseudomonas aeruginosa pyocyanin. Proc Natl Acad Sci USA 100 : 14315 14320.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14315-14320
    • Ran, H.1    Hassett, D.J.2    Lau, G.W.3
  • 45
    • 0016515874 scopus 로고
    • Pseudomonas aeruginosa infections: Persisting problems and current research to find new therapies
    • Reynolds, H.Y., Levine, A.S., Wood, R.E., Zierdt, C.H., Dale, D.C. Pennington, J.E. (1975) Pseudomonas aeruginosa infections: persisting problems and current research to find new therapies. Ann Intern Med 82 : 819 831.
    • (1975) Ann Intern Med , vol.82 , pp. 819-831
    • Reynolds, H.Y.1    Levine, A.S.2    Wood, R.E.3    Zierdt, C.H.4    Dale, D.C.5    Pennington, J.E.6
  • 46
    • 65649121900 scopus 로고    scopus 로고
    • Inactivation of the hmgA gene of Pseudomonas aeruginosa leads to pyomelanin hyperproduction, stress resistance and increased persistence in chronic lung infection
    • Rodríguez-Rojas, A., Mena, A., Martín, S., Borrell, N., Oliver, A. Blázquez, J. (2009) Inactivation of the hmgA gene of Pseudomonas aeruginosa leads to pyomelanin hyperproduction, stress resistance and increased persistence in chronic lung infection. Microbiology 155 : 1050 1057.
    • (2009) Microbiology , vol.155 , pp. 1050-1057
    • Rodríguez-Rojas, A.1    Mena, A.2    Martín, S.3    Borrell, N.4    Oliver, A.5    Blázquez, J.6
  • 48
    • 0029061955 scopus 로고
    • An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosa
    • Schweizer, H.P. Hoang, T. (1995) An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosa. Gene 158 : 15 22.
    • (1995) Gene , vol.158 , pp. 15-22
    • Schweizer, H.P.1    Hoang, T.2
  • 50
    • 50249123949 scopus 로고    scopus 로고
    • Conversion of Bacillus subtilis OhrR from a 1-Cys to a 2-Cys peroxide sensor
    • Soonsanga, S., Lee, J.W. Helmann, J.D. (2008) Conversion of Bacillus subtilis OhrR from a 1-Cys to a 2-Cys peroxide sensor. J Bacteriol 190 : 5738 5745.
    • (2008) J Bacteriol , vol.190 , pp. 5738-5745
    • Soonsanga, S.1    Lee, J.W.2    Helmann, J.D.3
  • 52
    • 0034944405 scopus 로고    scopus 로고
    • Complex regulation of the organic hydroperoxide resistance gene (ohr) from Xanthomonas involves OhrR, a novel organic peroxide-inducible negative regulator, and posttranscriptional modifications
    • Sukchawalit, R., Loprasert, S., Atichartpongkul, S. Mongkolsuk, S. (2001) Complex regulation of the organic hydroperoxide resistance gene (ohr) from Xanthomonas involves OhrR, a novel organic peroxide-inducible negative regulator, and posttranscriptional modifications. J Bacteriol 183 : 4405 4412.
    • (2001) J Bacteriol , vol.183 , pp. 4405-4412
    • Sukchawalit, R.1    Loprasert, S.2    Atichartpongkul, S.3    Mongkolsuk, S.4
  • 54
    • 31944442501 scopus 로고    scopus 로고
    • Quorum sensing: Dynamic response of Pseudomonas aeruginosa to external signals
    • Wagner, V.E., Frelinger, J.G., Barth, R.K. Iglewski, B.H. (2006) Quorum sensing: dynamic response of Pseudomonas aeruginosa to external signals. Trends Microbiol 14 : 55 58.
    • (2006) Trends Microbiol , vol.14 , pp. 55-58
    • Wagner, V.E.1    Frelinger, J.G.2    Barth, R.K.3    Iglewski, B.H.4
  • 55
    • 31344443334 scopus 로고    scopus 로고
    • Ligand-responsive transcriptional regulation by members of the MarR family of winged helix proteins
    • Wilkinson, S.P. Grove, A. (2006) Ligand-responsive transcriptional regulation by members of the MarR family of winged helix proteins. Curr Issues Mol Biol 8 : 51 62.
    • (2006) Curr Issues Mol Biol , vol.8 , pp. 51-62
    • Wilkinson, S.P.1    Grove, A.2
  • 56
    • 51149109323 scopus 로고    scopus 로고
    • Role of quorum sensing by Pseudomonas aeruginosa in microbial keratitis and cystic fibrosis
    • Willcox, M.D., Zhu, H., Conibear, T.C., Hume, E.B., Givskov, M., Kjelleberg, S. Rice, S.A. (2008) Role of quorum sensing by Pseudomonas aeruginosa in microbial keratitis and cystic fibrosis. Microbiology 154 : 2184 2194.
    • (2008) Microbiology , vol.154 , pp. 2184-2194
    • Willcox, M.D.1    Zhu, H.2    Conibear, T.C.3    Hume, E.B.4    Givskov, M.5    Kjelleberg, S.6    Rice, S.A.7
  • 57
    • 0023777725 scopus 로고
    • Measurement of Pseudomonas aeruginosa phenazine pigments in sputum and assessment of their contribution to sputum sol toxicity for respiratory epithelium
    • Wilson, R., Sykes, D.A., Watson, D., Rutman, A., Taylor, G.W. Cole, P.J. (1988) Measurement of Pseudomonas aeruginosa phenazine pigments in sputum and assessment of their contribution to sputum sol toxicity for respiratory epithelium. Infect Immun 56 : 2515 2517.
    • (1988) Infect Immun , vol.56 , pp. 2515-2517
    • Wilson, R.1    Sykes, D.A.2    Watson, D.3    Rutman, A.4    Taylor, G.W.5    Cole, P.J.6
  • 58
    • 57449113839 scopus 로고    scopus 로고
    • The role of quorum sensing in chronic cystic fibrosis Pseudomonas aeruginosa infections
    • Winstanley, C. Fothergill, J.L. (2009) The role of quorum sensing in chronic cystic fibrosis Pseudomonas aeruginosa infections. FEMS Microbiol Lett 290 : 1 9.
    • (2009) FEMS Microbiol Lett , vol.290 , pp. 1-9
    • Winstanley, C.1    Fothergill, J.L.2
  • 60
    • 46049083393 scopus 로고    scopus 로고
    • Involvement of a novel efflux system in biofilm-specific resistance to antibiotics
    • Zhang, L. Mah, T.F. (2008) Involvement of a novel efflux system in biofilm-specific resistance to antibiotics. J Bacteriol 190 : 4447 4452.
    • (2008) J Bacteriol , vol.190 , pp. 4447-4452
    • Zhang, L.1    Mah, T.F.2


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