Inactivation of the hmgA gene of Pseudomonas aeruginosa leads to pyomelanin hyperproduction, stress resistance and increased persistence in chronic lung infection

Microbiology

Volumn 155, Issue 4, 2009, Pages 1050-1057

  Rodríguez Rojas, Alexandro ^a   Mena, Ana ^b   Martín, Soledad ^a   Borrell, Nuria ^b   Oliver, Antonio ^b   Blázquez, Jesús ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b HOSPITAL UNIVERSITARIO SON ESPASES   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTAZIDIME; CIPROFLOXACIN; HIGH MOBILITY GROUP A PROTEIN; HOMOGENTISATE 1,2 DIOXYGENASE; IMIPENEM; PIGMENT; PYOMELANIN; TOBRAMYCIN; UNCLASSIFIED DRUG; MELANIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CHRONIC DISEASE; CONTROLLED STUDY; EVOLUTIONARY ADAPTATION; GENE DISRUPTION; GENE INACTIVATION; GENE INSERTION; GENE LOCATION; GENETIC COMPLEMENTATION; LUNG INFECTION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERSISTENT INFECTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; TRANSPOSON; ACUTE DISEASE; ANIMAL; BIOSYNTHESIS; CYSTIC FIBROSIS; FEMALE; GENE SILENCING; GENETICS; HEAT SHOCK RESPONSE; HUMAN; LUNG DISEASE; METABOLISM; MICROBIOLOGY; MORTALITY; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; PSEUDOMONAS INFECTION; UPREGULATION;

MURINAE; PSEUDOMONAS AERUGINOSA;

ACUTE DISEASE; ANIMALS; CHRONIC DISEASE; CYSTIC FIBROSIS; FEMALE; GENE SILENCING; HEAT-SHOCK RESPONSE; HOMOGENTISATE 1,2-DIOXYGENASE; HUMANS; LUNG DISEASES; MELANINS; MICE; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; UP-REGULATION;

EID: 65649121900     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.024745-0     Document Type: Article

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