Inhibition of phosphatidylinositol 3-kinase signaling in hepatic stellate cells blocks the progression of hepatic fibrosis

Hepatology

Volumn 50, Issue 5, 2009, Pages 1512-1523

  Son, Gakuhei ^a   Hines, Ian N ^a   Lindquist, Jeff ^a   Schrum, Laura W ^b   Rippe, Richard A ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; S6 KINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL DEATH; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVATION; ENZYME INHIBITION; EXTRACELLULAR MATRIX; FIBROGENESIS; LIVER CELL; LIVER FIBROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; STELLATE CELL;

ACTINS; ADENOVIRIDAE; ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN TYPE I; CYCLIN D1; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; EXTRACELLULAR MATRIX; HEPATIC STELLATE CELLS; LIVER CIRRHOSIS; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION;

EID: 72949093788     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.23186     Document Type: Article

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