CD4+CD25+ T regulatory cells limit effector T cells and favor the progression of brucellosis in BALB/c mice

Microbes and Infection

Volumn 12, Issue 1, 2010, Pages 3-10

  Pasquali, Paolo ^a   Thornton, Angela M ^b   Vendetti, Silvia ^a   Pistoia, Claudia ^a   Petrucci, Paola ^a   Tarantino, Michela ^a   Pesciaroli, Michele ^a   Ruggeri, Franco ^a   Battistoni, Andrea ^c   Shevach, Ethan M ^b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Brucella; Immune response; Immunology; Mouse model; Regulatory T cells

Indexed keywords

GAMMA INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; BRUCELLA ABORTUS; BRUCELLOSIS; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; EFFECTOR CELL; FEMALE; IMMUNE RESPONSE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SCID MOUSE; SPLEEN CELL; T CELL DEPLETION;

ANIMALS; BRUCELLA ABORTUS; BRUCELLOSIS; CD4-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; FEMALE; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MICE; MICE, INBRED BALB C; T-LYMPHOCYTES, REGULATORY;

BACTERIA (MICROORGANISMS); BRUCELLA; BRUCELLA MELITENSIS BIOVAR ABORTUS; MUS;

EID: 72949084389     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2009.09.005     Document Type: Article

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