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Volumn 22, Issue 11, 2009, Pages 1817-1826

Dehydroeburicoic acid induces calcium- and calpain-dependent necrosis in human U87MG glioblastomas

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL THIAZOL 2 YL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ADENOSINE TRIPHOSPHATE; BROMINE DERIVATIVE; CALCIUM; CALPAIN; CALPASTATIN; CASPASE; DEHYDROEBURICOIC ACID; EDETIC ACID; EGTAZIC ACID; FODRIN; LACTATE DEHYDROGENASE; LIPOCORTIN 5; PROPIDIUM IODIDE; TRITERPENE; UNCLASSIFIED DRUG;

EID: 72749091027     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx9002275     Document Type: Article
Times cited : (26)

References (46)
  • 1
    • 16644389757 scopus 로고    scopus 로고
    • Cytotoxicity and DNA topoisomerases inhibitory activity of constituents from the sclerotium of Poria cocos
    • Li, G., Xu, M. L., Lee, C. S., Woo, M. H., Chang, H. W., and Son, J. K. (2004) Cytotoxicity and DNA topoisomerases inhibitory activity of constituents from the sclerotium of Poria cocos. Arch. Pharmacal Res. 27, 829-833. (Pubitemid 43073702)
    • (2004) Archives of Pharmacal Research , vol.27 , Issue.8 , pp. 829-833
    • Li, G.1    Xu, M.-L.2    Lee, C.-S.3    Woo, M.-H.4    Chang, H.-W.5    Son, J.-K.6
  • 2
    • 15244358231 scopus 로고    scopus 로고
    • Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell lines
    • Hsu, Y. L., Kuo, Y. C., Kuo, P. L., Ng, L. T., Kuo, Y. H., and Lin, C. C. (2005) Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell lines. Cancer Lett. 221, 77-89.
    • (2005) Cancer Lett. , vol.221 , pp. 77-89
    • Hsu, Y.L.1    Kuo, Y.C.2    Kuo, P.L.3    Ng, L.T.4    Kuo, Y.H.5    Lin, C.C.6
  • 3
    • 33745193250 scopus 로고    scopus 로고
    • Apoptotic effects of Antrodia cinnamomea fruiting bodies extract are mediated through calcium and calpain-dependent pathways in Hep 3B cells
    • Kuo, P. L., Hsu, Y. L., Cho, C. Y., Ng, L. T., Kuo, Y. H., and Lin, C. C. (2006) Apoptotic effects of Antrodia cinnamomea fruiting bodies extract are mediated through calcium and calpain-dependent pathways in Hep 3B cells. Food Chem. Toxicol. 44, 1316-1326.
    • (2006) Food Chem. Toxicol. , vol.44 , pp. 1316-1326
    • Kuo, P.L.1    Hsu, Y.L.2    Cho, C.Y.3    Ng, L.T.4    Kuo, Y.H.5    Lin, C.C.6
  • 4
    • 1642344402 scopus 로고    scopus 로고
    • Antiproliferative and differentiating effects of polysaccharide fraction from fu-ling (Poria cocos) on human leukemic U937 and HL-60 cells
    • Chen, Y. Y., and Chang, H. M. (2004) Antiproliferative and differentiating effects of polysaccharide fraction from fu-ling (Poria cocos) on human leukemic U937 and HL-60 cells. Food Chem. Toxicol. 42, 759-769.
    • (2004) Food Chem. Toxicol. , vol.42 , pp. 759-769
    • Chen, Y.Y.1    Chang, H.M.2
  • 5
    • 0037210695 scopus 로고    scopus 로고
    • Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides
    • DOI 10.1007/s00253-002-1076-7
    • Wasser, S. P. (2002) Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl. Microbiol. Biotechnol. 60, 258-274. (Pubitemid 35352092)
    • (2003) Applied Microbiology and Biotechnology , vol.60 , Issue.3 , pp. 258-274
    • Wasser, S.1
  • 6
    • 0015496681 scopus 로고
    • Steroids and related natural products. 66. Structural modification of the triterpene A ring
    • Pettit, G. R., and Dias, J. R. (1972) Steroids and related natural products. 66. Structural modification of the triterpene A ring. J. Org. Chem. 37, 973-976.
    • (1972) J. Org. Chem. , vol.37 , pp. 973-976
    • Pettit, G.R.1    Dias, J.R.2
  • 7
    • 0000954753 scopus 로고
    • Triterpenes of Poria cocos
    • Tai, T., Akahori, A., and Shingu, T. (1993) Triterpenes of Poria cocos. Phytochemistry 32, 1239-1244.
    • (1993) Phytochemistry , vol.32 , pp. 1239-1244
    • Tai, T.1    Akahori, A.2    Shingu, T.3
  • 8
    • 0030050517 scopus 로고    scopus 로고
    • Steroids and triterpenoids of Antrodia cinnamomea - A fungus parasitic on Cinnamomum micranthum
    • DOI 10.1016/0031-9422(95)00767-9
    • Yang, S. W., Shen, Y. C., and Chen, C. H. (1996) Steroids and triterpenoids of Antodia cinnamomea - A fungus parasitic on Cinnamomum micranthum. Phytochemistry 41, 1389-1392. (Pubitemid 3036990)
    • (1996) Phytochemistry , vol.41 , Issue.5 , pp. 1389-1392
    • Yang, S.-W.1    Shen, Y.-C.2    Chen, C.-H.3
  • 9
    • 15744404456 scopus 로고    scopus 로고
    • Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells
    • Hsu, Y. L., Kuo, P. L., Lin, L. T., and Lin, C. C. (2005) Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells. J. Pharmacol. Exp. Ther. 313, 333-344.
    • (2005) J. Pharmacol. Exp. Ther. , vol.313 , pp. 333-344
    • Hsu, Y.L.1    Kuo, P.L.2    Lin, L.T.3    Lin, C.C.4
  • 10
    • 0033638986 scopus 로고    scopus 로고
    • Effect of saikosaponin, a triterpene saponin, on apoptosis in lymphocytes: Association with c-myc, p53, and bcl-2 mRNA
    • Hsu, M. J., Cheng, J. S., and Huang, H. C. (2000) Effect of saikosaponin, a triterpene saponin, on apoptosis in lymphocytes: Association with c-myc, p53, and bcl-2 mRNA. Br. J. Pharmacol. 131, 1285-1293.
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 1285-1293
    • Hsu, M.J.1    Cheng, J.S.2    Huang, H.C.3
  • 13
    • 0036316721 scopus 로고    scopus 로고
    • PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway
    • DOI 10.1038/sj.cdd.4400982
    • Wan, X., Yokoyama, Y., Shinohara, A., Takahashi, Y., and Tamaya, T. (2002) PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway. Cell Death Differ. 9, 414-420. (Pubitemid 34814621)
    • (2002) Cell Death and Differentiation , vol.9 , Issue.4 , pp. 414-420
    • Wan, X.1    Yokoyama, Y.2    Shinohara, A.3    Takahashi, Y.4    Tamaya, T.5
  • 16
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry, N. A., and Lazebnik, Y. (1998) Caspases: Enemies within. Science 281, 1312-1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 17
    • 0842281645 scopus 로고    scopus 로고
    • Cell Death: Critical Control Points
    • DOI 10.1016/S0092-8674(04)00046-7
    • Danial, N. N., and Korsmeyer, S. J. (2004) Cell death: Critical control points. Cell 116, 205-219. (Pubitemid 38167313)
    • (2004) Cell , vol.116 , Issue.2 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 18
    • 0141884305 scopus 로고    scopus 로고
    • Diversity in the mechanisms of neuronal cell death
    • DOI 10.1016/S0896-6273(03)00601-9
    • Yuan, J., Lipinski, M., and Degterev, A. (2003) Diversity in the mechanisms of neuronal cell death. Neuron 40, 401-413. (Pubitemid 37244104)
    • (2003) Neuron , vol.40 , Issue.2 , pp. 401-413
    • Yuan, J.1    Lipinski, M.2    Degterev, A.3
  • 19
    • 20444375511 scopus 로고    scopus 로고
    • Proteolytic mechanisms in necrotic cell death and neurodegeneration
    • DOI 10.1016/j.febslet.2005.03.052, PII S0014579305003984
    • Artal-Sanz, M., and Tavernarakis, N. (2005) Proteolytic mechanisms in necrotic cell death and neurodegeneration. FEBS Lett. 579, 3287-3296. (Pubitemid 40804676)
    • (2005) FEBS Letters , vol.579 , Issue.15 , pp. 3287-3296
    • Artal-Sanz, M.1    Tavernarakis, N.2
  • 20
    • 0029899405 scopus 로고    scopus 로고
    • + currents in rat cerebellar granule neurones of a membrane-permeable analogue of the calcium chelator BAPTA
    • + currents in rat cerebellar granule neurones of a membrane-permeable analogue of the calcium chelator BAPTA. Br. J. Pharmacol. 118, 1772-1778.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1772-1778
    • Watkins, C.S.1    Mathie, A.2
  • 21
    • 33748961353 scopus 로고    scopus 로고
    • Mitochondrial membrane permeability transition and cell death
    • DOI 10.1016/j.bbabio.2006.03.017, PII S0005272806000727, Mitochondria: from Molecular Insight to Physiology and Pathology
    • Tsujimoto, Y., Nakagawa, T., and Shimizu, S. (2006) Mitochondrial membrane permeability transition and cell death. Biochim. Biophys. Acta 1757, 1297-1300. (Pubitemid 44442106)
    • (2006) Biochimica et Biophysica Acta - Bioenergetics , vol.1757 , Issue.9-10 , pp. 1297-1300
    • Tsujimoto, Y.1    Nakagawa, T.2    Shimizu, S.3
  • 22
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • DOI 10.1152/physrev.00013.2006
    • Kroemer, G., Galluzzi, L., and Brenner, C. (2007) Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 87, 99-163. (Pubitemid 46209992)
    • (2007) Physiological Reviews , vol.87 , Issue.1 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 23
    • 0030915587 scopus 로고    scopus 로고
    • Intracellular ATP levels determine cell death fate by apoptosis or necrosis
    • Eguchi, Y., Shimizu, S., and Tsujimoto, Y. (1997) Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res. 57, 1835-1840. (Pubitemid 27209706)
    • (1997) Cancer Research , vol.57 , Issue.10 , pp. 1835-1840
    • Eguchi, Y.1    Shimizu, S.2    Tsujimoto, Y.3
  • 25
    • 27844595293 scopus 로고    scopus 로고
    • Caspase and calpain function in cell death: Bridging the gap between apoptosis and necrosis
    • Harwood, S. M., Yaqoob, M. M., and Allen, D. A. (2005) Caspase and calpain function in cell death: Bridging the gap between apoptosis and necrosis. Ann. Clin. Biochem. 42, 415-431.
    • (2005) Ann. Clin. Biochem. , vol.42 , pp. 415-431
    • Harwood, S.M.1    Yaqoob, M.M.2    Allen, D.A.3
  • 26
    • 0029854806 scopus 로고    scopus 로고
    • Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: Contributory roles of both protease families in neuronal apoptosis
    • Nath, R., Raser, K. J., Stafford, D., Hajimohammadreza, I., Posner, A., Allen, H., Talanian, R. V., Yuen, P., Gilbertsen, R. B., and Wang, K. K. (1996) Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: Contributory roles of both protease families in neuronal apoptosis. Biochem. J. 319 (Part 3), 683-690. (Pubitemid 26386177)
    • (1996) Biochemical Journal , vol.319 , Issue.3 , pp. 683-690
    • Nath, R.1    Raser, K.J.2    Stafford, D.3    Hajimohammadreza, I.4    Posner, A.5    Allen, H.6    Talanian, R.V.7    Yuen, P.-W.8    Gilbertsen, R.B.9    Wang, K.K.W.10
  • 28
    • 7744235672 scopus 로고    scopus 로고
    • Death by design: Apoptosis, necrosis and autophagy
    • DOI 10.1016/j.ceb.2004.09.011, PII S0955067404001474
    • Edinger, A. L., and Thompson, C. B. (2004) Death by design: Apoptosis, necrosis and autophagy. Curr. Opin. Cell Biol. 16, 663-669. (Pubitemid 39463117)
    • (2004) Current Opinion in Cell Biology , vol.16 , Issue.6 , pp. 663-669
    • Edinger, A.L.1    Thompson, C.B.2
  • 31
    • 0034668833 scopus 로고    scopus 로고
    • Mitochondria and calcium: From cell signalling to cell death
    • Part 1
    • Duchen, M. R. (2000) Mitochondria and calcium: From cell signalling to cell death. J. Physiol. 529 (Part 1), 57-68.
    • (2000) J. Physiol. , vol.529 , pp. 57-68
    • Duchen, M.R.1
  • 33
    • 15844407874 scopus 로고    scopus 로고
    • Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
    • DOI 10.1038/nature03317
    • Nakagawa, T., Shimizu, S., Watanabe, T., Yamaguchi, O., Otsu, K., Yamagata, H., Inohara, H., Kubo, T., and Tsujimoto, Y. (2005) Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434, 652-658. (Pubitemid 40488558)
    • (2005) Nature , vol.434 , Issue.7033 , pp. 652-658
    • Nakagawa, T.1    Shimizu, S.2    Watanabe, T.3    Yamaguchi, O.4    Otsu, K.5    Yamagata, H.6    Inohara, H.7    Kubo, T.8    Tsujimoto, Y.9
  • 36
    • 0037214421 scopus 로고    scopus 로고
    • Calpain mediates progressive plasma membrane permeability and proteolysis of cytoskeleton-associated paxillin, talin, and vinculin during renal cell death
    • DOI 10.1124/jpet.102.043406
    • Liu, X., and Schnellmann, R. G. (2003) Calpain mediates progressive plasma membrane permeability and proteolysis of cytoskeleton-associated paxillin, talin, and vinculin during renal cell death. J. Pharmacol. Exp. Ther. 304, 63-70. (Pubitemid 36008913)
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.304 , Issue.1 , pp. 63-70
    • Liu, X.1    Schnellmann, R.G.2
  • 38
    • 84856583036 scopus 로고    scopus 로고
    • Calpain in the CNS: From synaptic function to neurotoxicity
    • Liu, J., Liu, M. C., and Wang, K. K. (2008) Calpain in the CNS: From synaptic function to neurotoxicity. Sci. Signaling 1, re1.
    • (2008) Sci. Signaling , vol.1
    • Liu, J.1    Liu, M.C.2    Wang, K.K.3
  • 39
    • 33846502748 scopus 로고    scopus 로고
    • Calpain-Mediated mGluR1alpha Truncation: A Key Step in Excitotoxicity
    • DOI 10.1016/j.neuron.2006.12.020, PII S0896627306010257
    • Xu, W., Wong, T. P., Chery, N., Gaertner, T., Wang, Y. T., and Baudry, M. (2007) Calpain-mediated mGluR1alpha truncation: A key step in excitotoxicity. Neuron 53, 399-412. (Pubitemid 46161261)
    • (2007) Neuron , vol.53 , Issue.3 , pp. 399-412
    • Xu, W.1    Wong, T.P.2    Chery, N.3    Gaertner, T.4    Wang, Y.T.5    Baudry, M.6
  • 40
    • 4544262395 scopus 로고    scopus 로고
    • Dehydrotrametenonic acid and dehydroeburiconic acid from Poria cocos and their inhibitory effects on eukaryotic DNA polymerase alpha and beta
    • DOI 10.1271/bbb.68.448
    • Akihisa, T., Mizushina, Y., Ukiya, M., Oshikubo, M., Kondo, S., Kimura, Y., Suzuki, T., and Tai, T. (2004) Dehydrotrametenonic acid and dehydroeburiconic acid from Poria cocos and their inhibitory effects on eukaryotic DNA polymerase alpha and beta. Biosci., Biotechnol., Biochem. 68, 448-450. (Pubitemid 39251550)
    • (2004) Bioscience, Biotechnology and Biochemistry , vol.68 , Issue.2 , pp. 448-450
    • Akihisa, T.1    Mizushina, Y.2    Ukiya, M.3    Oshikubo, M.4    Kondo, S.5    Kimura, Y.6    Suzuki, T.7    Tai, T.8
  • 41
    • 1942471903 scopus 로고    scopus 로고
    • A novel DNA topoisomerase inhibitor: Dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos
    • DOI 10.1111/j.1349-7006.2004.tb03215.x
    • Mizushina, Y., Akihisa, T., Ukiya, M., Murakami, C., Kuriyama, I., Xu, X., Yoshida, H., and Sakaguchi, K. (2004) A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos. Cancer Sci. 95, 354-360. (Pubitemid 38519477)
    • (2004) Cancer Science , vol.95 , Issue.4 , pp. 354-360
    • Mizushina, Y.1    Akihisa, T.2    Ukiya, M.3    Murakami, C.4    Kuriyama, I.5    Xu, X.6    Yoshida, H.7    Sakaguchi, K.8
  • 42
    • 0033556544 scopus 로고    scopus 로고
    • The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187
    • DOI 10.1006/taap.1998.8580
    • Qian, T., Herman, B., and Lemasters, J. J. (1999) The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187. Toxicol. Appl. Pharmacol. 154, 117-125. (Pubitemid 29072493)
    • (1999) Toxicology and Applied Pharmacology , vol.154 , Issue.2 , pp. 117-125
    • Qian, T.1    Herman, B.2    Lemasters, J.J.3
  • 44
    • 70349269114 scopus 로고    scopus 로고
    • Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells
    • Yeh, C. T., Rao, Y. K., Yao, C. J., Yeh, C. F., Li, C. H., Chuang, S. E., Luong, J. H., Lai, G. M., and Tzeng, Y. M. (2009) Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells. Cancer Lett. 285, 73-79.
    • (2009) Cancer Lett. , vol.285 , pp. 73-79
    • Yeh, C.T.1    Rao, Y.K.2    Yao, C.J.3    Yeh, C.F.4    Li, C.H.5    Chuang, S.E.6    Luong, J.H.7    Lai, G.M.8    Tzeng, Y.M.9
  • 45
    • 0037330831 scopus 로고    scopus 로고
    • Necrosis: A specific form of programmed cell death?
    • DOI 10.1016/S0014-4827(02)00027-7
    • Proskuryakov, S. Y., Konoplyannikov, A. G., and Gabai, V. L. (2003) Necrosis: A specific form of programmed cell death? Exp. Cell Res. 283, 1-16. (Pubitemid 36259891)
    • (2003) Experimental Cell Research , vol.283 , Issue.1 , pp. 1-16
    • Proskuryakov, S.Y.1    Konoplyannikov, A.G.2    Gabai, V.L.3
  • 46
    • 0033598713 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
    • Ha, H. C., and Snyder, S. H. (1999) Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc. Natl. Acad. Sci. U.S.A. 96, 13978-13982.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 13978-13982
    • Ha, H.C.1    Snyder, S.H.2


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