Mitochondrial dysfunction is related to necrosis-like programmed cell death induced by A23187 in CEM cells

European Journal of Pharmacology

Volumn 516, Issue 3, 2005, Pages 187-196

  Hamahata, Keigo ^a   Adachi, Souichi ^a   Matsubara, Hiroshi ^a   Okada, Masayuki ^a   Imai, Tsuyoshi ^a   Watanabe, Ken Ichiro ^a   Toyokuni, Shin Ya ^a   Ueno, Masaki ^b   Wakabayashi, Shigeo ^c   Katanosaka, Yuki ^c   Akiba, Satoshi ^d   Kubota, Masaru ^e   Nakahata, Tatsutoshi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KAGAWA UNIVERSITY   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^e KOBE CITY MEDICAL CENTER GENERAL HOSPITAL   (Japan)

Author keywords

Apoptosis; Bcl 2; Calcium ionophore; Clonazepam; Mitochondria; Necrosis

Indexed keywords

7 CHLORO 5 (2 CHLOROPHENYL) 1,5 DIHYDRO 4,1 BENZOTHIAZEPIN 2(3H) ONE; CALCIMYCIN; CLONAZEPAM; CYCLOSPORIN A; SODIUM CALCIUM EXCHANGE PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER CELL; CANCER CELL CULTURE; CELL DEATH; CELL MEMBRANE; CELL STRAIN HL 60; CHROMATIN CONDENSATION; CONTROLLED STUDY; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION PERMEABILITY TRANSITION; MITOCHONDRION SWELLING; PRIORITY JOURNAL;

APOPTOSIS; CALCIMYCIN; CALCIUM; CASPASE 3; CASPASES; CELL LINE, TUMOR; CELL SHAPE; CLONAZEPAM; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLOW CYTOMETRY; HL-60 CELLS; HUMANS; INTRACELLULAR MEMBRANES; IONOPHORES; MEMBRANE POTENTIALS; MITOCHONDRIA; NECROSIS; PHOSPHOLIPASES; PROTO-ONCOGENE PROTEINS C-BCL-2; THIAZEPINES; TIME FACTORS;

EID: 21544437612     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.04.018     Document Type: Article

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