Impaired processing of human pro-islet amyloid polypeptide is not a causative factor for fibril formation or membrane damage in vitro

Biochemistry

Volumn 48, Issue 46, 2009, Pages 10918-10925

  Khemtémourian, Lucie ^a   Casarramona, Gemma Lahoz ^b   Suylen, Dennis P L ^c   Hackeng, Tilman M ^c   Meeldijk, Johannes D ^a   De Kruijff, Ben ^a   Höppener, Jo W M ^b   Killian, J Antoinette ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID FIBRIL; BARRIER PROPERTIES; CATALYZING EFFECTS; FIBRIL FORMATION; FIBRILLOGENESIS; HELICAL STRUCTURES; HUMAN ISLETS; IN-VITRO; INTRACELLULAR TRANSPORT; LIPID VESICLES; MEMBRANE DAMAGE; MEMBRANE INSERTION; MEMBRANE LEAKAGES; PANCREATIC ISLET; TYPE 2 DIABETES MELLITUS;

BIOCHEMISTRY; GLYCOPROTEINS;

MEMBRANES;

AMYLIN; AMYLOID; HORMONE PRECURSOR;

ALPHA HELIX; ARTICLE; BETA SHEET; HORMONE STRUCTURE; HUMAN; IN VITRO STUDY; LIPID VESICLE; MEMBRANE DAMAGE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN PROCESSING;

AMYLOID; CIRCULAR DICHROISM; FLUORESCEINS; HUMANS; KINETICS; MEMBRANES, ARTIFICIAL; MODELS, MOLECULAR; PERMEABILITY; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, SECONDARY; SPECTROMETRY, FLUORESCENCE; SURFACE TENSION; THIAZOLES; UNILAMELLAR LIPOSOMES;

EID: 72749086820     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901076d     Document Type: Article

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