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Volumn 55, Issue 1, 2010, Pages 52-59

Histomorphometric analysis and immunolocalization of RANKL and OPG during the alveolar healing process in female ovariectomized rats treated with oestrogen or raloxifene

Author keywords

Alveolar process; Estradiol; Osteoblasts; Osteoprotegerin; Ovariectomy; Raloxifene; RANKL

Indexed keywords

ESTROGEN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RALOXIFENE;

EID: 72649098090     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archoralbio.2009.11.001     Document Type: Article
Times cited : (43)

References (49)
  • 2
    • 0001822211 scopus 로고    scopus 로고
    • Embryology and cellular biology of bone
    • Avioli L.V., and Krane S.M. (Eds), Academic Press, New York p. 1-22
    • Raisz L.G., and Rodan G.A. Embryology and cellular biology of bone. In: Avioli L.V., and Krane S.M. (Eds). Metabolic bone disease and clinically related disorders (1998), Academic Press, New York p. 1-22
    • (1998) Metabolic bone disease and clinically related disorders
    • Raisz, L.G.1    Rodan, G.A.2
  • 3
    • 0034455103 scopus 로고    scopus 로고
    • Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
    • Manolagas S.C. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev 21 2 (2000) 115-137
    • (2000) Endocr Rev , vol.21 , Issue.2 , pp. 115-137
    • Manolagas, S.C.1
  • 4
    • 0026090089 scopus 로고
    • Bone-cell changes in estrogen-induced bone-mass increase in mice: dissociation of osteoclasts from bone surfaces
    • Liu C.C., and Howard G.A. Bone-cell changes in estrogen-induced bone-mass increase in mice: dissociation of osteoclasts from bone surfaces. Anat Rec 229 2 (1991) 240-250
    • (1991) Anat Rec , vol.229 , Issue.2 , pp. 240-250
    • Liu, C.C.1    Howard, G.A.2
  • 5
    • 0036548450 scopus 로고    scopus 로고
    • Effects of ovariectomy on trabecular structures of rat alveolar bone
    • Tanaka M., Ejiri S., Toyooka E., Kohno S., and Ozawa H. Effects of ovariectomy on trabecular structures of rat alveolar bone. J Periodontal Res 37 2 (2002) 161-165
    • (2002) J Periodontal Res , vol.37 , Issue.2 , pp. 161-165
    • Tanaka, M.1    Ejiri, S.2    Toyooka, E.3    Kohno, S.4    Ozawa, H.5
  • 6
    • 7044264638 scopus 로고    scopus 로고
    • Alendronate may protect against increased periodontitis-related bone loss in estrogen-deficient rats
    • Duarte M.P., de Assis D.R., Casati M.Z., Sallum A.W., Sallum E.A., and Nociti Jr. F.H. Alendronate may protect against increased periodontitis-related bone loss in estrogen-deficient rats. J Periodontol 75 9 (2004) 1196-1202
    • (2004) J Periodontol , vol.75 , Issue.9 , pp. 1196-1202
    • Duarte, M.P.1    de Assis, D.R.2    Casati, M.Z.3    Sallum, A.W.4    Sallum, E.A.5    Nociti Jr., F.H.6
  • 7
    • 0034284550 scopus 로고    scopus 로고
    • Therapeutic approaches to bone diseases
    • Rodan G.A., and Martin T.J. Therapeutic approaches to bone diseases. Science 289 5484 (2000) 1508-1514
    • (2000) Science , vol.289 , Issue.5484 , pp. 1508-1514
    • Rodan, G.A.1    Martin, T.J.2
  • 8
    • 33745886847 scopus 로고    scopus 로고
    • Treatment of menopausal symptoms in family medicine settings following the Women's Health Initiative findings
    • Burg M.A., Fraser K., Gui S., Grant K., Kosch S.G., Nierenberg B., et al. Treatment of menopausal symptoms in family medicine settings following the Women's Health Initiative findings. J Am Board Fam Med 19 2 (2006) 122-131
    • (2006) J Am Board Fam Med , vol.19 , Issue.2 , pp. 122-131
    • Burg, M.A.1    Fraser, K.2    Gui, S.3    Grant, K.4    Kosch, S.G.5    Nierenberg, B.6
  • 10
    • 0033581212 scopus 로고    scopus 로고
    • Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators
    • Ettinger B., Black D.M., Mitlak B.H., Knicherbocker R.K., Nickelsen T., Genant H.K., et al. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. J Am Med Assoc 282 7 (1999) 637-645
    • (1999) J Am Med Assoc , vol.282 , Issue.7 , pp. 637-645
    • Ettinger, B.1    Black, D.M.2    Mitlak, B.H.3    Knicherbocker, R.K.4    Nickelsen, T.5    Genant, H.K.6
  • 11
    • 0033575083 scopus 로고    scopus 로고
    • The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial Multiple Outcomes of Raloxifene Evaluation
    • Cummings S.R., Eckert S., Krueger K.A., Grady D., Powles T.J., Cauley J.Á., et al. The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial Multiple Outcomes of Raloxifene Evaluation. J Am Med Assoc 281 23 (1999) 2189-2197
    • (1999) J Am Med Assoc , vol.281 , Issue.23 , pp. 2189-2197
    • Cummings, S.R.1    Eckert, S.2    Krueger, K.A.3    Grady, D.4    Powles, T.J.5    Cauley, J.Á.6
  • 12
    • 0037138787 scopus 로고    scopus 로고
    • Raloxifene and cardiovascular events in osteoporotic postmenopausal women: four-year results from the MORE (Multiple Outcomes of Raloxifene Evaluation) randomized trial
    • Barrett-Connor E., Grady D., Sashegyi A., Anderson P.W., Cox D.A., Hoszowski K., et al. Raloxifene and cardiovascular events in osteoporotic postmenopausal women: four-year results from the MORE (Multiple Outcomes of Raloxifene Evaluation) randomized trial. J Am Med Assoc 287 7 (2002) 847-857
    • (2002) J Am Med Assoc , vol.287 , Issue.7 , pp. 847-857
    • Barrett-Connor, E.1    Grady, D.2    Sashegyi, A.3    Anderson, P.W.4    Cox, D.A.5    Hoszowski, K.6
  • 13
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey D.L., Timms E., Tan H.-L., Kelley M.J., Dunstan C.R., Burgess T., et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93 2 (1998) 165-176
    • (1998) Cell , vol.93 , Issue.2 , pp. 165-176
    • Lacey, D.L.1    Timms, E.2    Tan, H.-L.3    Kelley, M.J.4    Dunstan, C.R.5    Burgess, T.6
  • 14
    • 13044316551 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
    • Hsu H., Lacey D.L., Dunstan C.R., Solovyev I., Colombero A., Timms E., et al. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci USA 96 7 (1999) 3540-3545
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.7 , pp. 3540-3545
    • Hsu, H.1    Lacey, D.L.2    Dunstan, C.R.3    Solovyev, I.4    Colombero, A.5    Timms, E.6
  • 15
    • 0031005576 scopus 로고    scopus 로고
    • Osteoprotegerin: a novel secreted protein involved in the regulation of bone density
    • Simonet W.S., Lacey D.L., Dunstan C.R., Kelley M., Chang M.S., Luthy R., et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 89 2 (1997) 309-319
    • (1997) Cell , vol.89 , Issue.2 , pp. 309-319
    • Simonet, W.S.1    Lacey, D.L.2    Dunstan, C.R.3    Kelley, M.4    Chang, M.S.5    Luthy, R.6
  • 16
    • 0015696431 scopus 로고
    • Wound healing following tooth extraction: histochemical study in rats
    • Okamoto T., and Russo M.C. Wound healing following tooth extraction: histochemical study in rats. Rev Fac Odontol Araçatuba 2 2 (1973) 153-169
    • (1973) Rev Fac Odontol Araçatuba , vol.2 , Issue.2 , pp. 153-169
    • Okamoto, T.1    Russo, M.C.2
  • 18
    • 84910870127 scopus 로고
    • Guide for the care and use of laboratory animals. DHHS publication
    • National Research Council, Department of Health and Human Services, NRC, Committee on Care and Use of Laboratory Animals of the Institute of Laboratory Animal Resources;
    • National Research Council. Guide for the care and use of laboratory animals. DHHS publication no. (NIH) 85-23 (rev.). Department of Health and Human Services, NRC, Committee on Care and Use of Laboratory Animals of the Institute of Laboratory Animal Resources; 1985.
    • (1985) (NIH) 85-23 (rev.)
  • 19
    • 0028432767 scopus 로고
    • Early alveolar ridge osteogenesis following tooth extraction in the rat
    • Hsieh Y.D., Devlin H., and Roberts C. Early alveolar ridge osteogenesis following tooth extraction in the rat. Arch Oral Biol 39 5 (1994) 425-428
    • (1994) Arch Oral Biol , vol.39 , Issue.5 , pp. 425-428
    • Hsieh, Y.D.1    Devlin, H.2    Roberts, C.3
  • 20
    • 0002545003 scopus 로고    scopus 로고
    • Animal models of bone disease
    • San Diego: Academic Press;
    • Geddes A. Animal models of bone disease. In: Principles of bone biology. San Diego: Academic Press; 1996. p. 1343.
    • (1996) Principles of bone biology , pp. 1343
    • Geddes, A.1
  • 22
    • 67349250747 scopus 로고    scopus 로고
    • Raloxifene reduces circulating levels of interleukin-7 and monocyte chemoattractant protein-1 in postmenopausal women
    • Yasui T., Uemura H., Hyodo S., Yamada M., Yamamoto S., Maegawa M., et al. Raloxifene reduces circulating levels of interleukin-7 and monocyte chemoattractant protein-1 in postmenopausal women. Atherosclerosis 204 2 (2009) 471-475
    • (2009) Atherosclerosis , vol.204 , Issue.2 , pp. 471-475
    • Yasui, T.1    Uemura, H.2    Hyodo, S.3    Yamada, M.4    Yamamoto, S.5    Maegawa, M.6
  • 23
    • 55349132677 scopus 로고    scopus 로고
    • Effects of selective oestrogen receptor modulators on proliferation in tissue cultures of pre- and postmenopausal human endometrium
    • Punyadeera C., Kamps R., Defrère S., Dijcks F., de Goeij A., Ederveen A., et al. Effects of selective oestrogen receptor modulators on proliferation in tissue cultures of pre- and postmenopausal human endometrium. J Steroid Biochem Mol Biol 112 1-3 (2008) 102-109
    • (2008) J Steroid Biochem Mol Biol , vol.112 , Issue.1-3 , pp. 102-109
    • Punyadeera, C.1    Kamps, R.2    Defrère, S.3    Dijcks, F.4    de Goeij, A.5    Ederveen, A.6
  • 24
    • 67349183354 scopus 로고    scopus 로고
    • Increased circulating heat shock protein 60 induced by menopause, stimulates apoptosis of osteoblast-lineage cells via up-regulation of toll-like receptors
    • Kim Y.S., Koh J.M., Lee Y.S., Kim B.J., Lee S.H., Lee K.U., et al. Increased circulating heat shock protein 60 induced by menopause, stimulates apoptosis of osteoblast-lineage cells via up-regulation of toll-like receptors. Bone 45 1 (2009) 68-76
    • (2009) Bone , vol.45 , Issue.1 , pp. 68-76
    • Kim, Y.S.1    Koh, J.M.2    Lee, Y.S.3    Kim, B.J.4    Lee, S.H.5    Lee, K.U.6
  • 25
    • 4143065666 scopus 로고    scopus 로고
    • Effect of an estrogen-deficient state and its therapy on bone loss resulting from an experimental periodontitis in rats
    • Duarte P.M., Gonçalves P.F., Sallum A.W., Sallum E.A., Casati M.Z., and Nociti Jr. F.H. Effect of an estrogen-deficient state and its therapy on bone loss resulting from an experimental periodontitis in rats. J Periodontal Res 39 2 (2004) 107-110
    • (2004) J Periodontal Res , vol.39 , Issue.2 , pp. 107-110
    • Duarte, P.M.1    Gonçalves, P.F.2    Sallum, A.W.3    Sallum, E.A.4    Casati, M.Z.5    Nociti Jr., F.H.6
  • 26
    • 33750458959 scopus 로고    scopus 로고
    • Estrogen and alendronate therapies may prevent the influence of estrogen deficiency on the tooth-supporting alveolar bone: a histometric study in rats
    • Duarte P.M., Gonçalves P.F., Casati M.Z., de Toledo S., Sallum E.A., and Nociti Jr. F.H. Estrogen and alendronate therapies may prevent the influence of estrogen deficiency on the tooth-supporting alveolar bone: a histometric study in rats. J Periodontal Res 41 6 (2006) 541-546
    • (2006) J Periodontal Res , vol.41 , Issue.6 , pp. 541-546
    • Duarte, P.M.1    Gonçalves, P.F.2    Casati, M.Z.3    de Toledo, S.4    Sallum, E.A.5    Nociti Jr., F.H.6
  • 28
    • 0029062602 scopus 로고
    • Maxillary molar extraction causes increased bone loss in the mandible of ovariectomized rats
    • Elovic R.P., Hipp J.A., and Hayes W.C. Maxillary molar extraction causes increased bone loss in the mandible of ovariectomized rats. J Bone Miner Res 10 7 (1995) 1087-1093
    • (1995) J Bone Miner Res , vol.10 , Issue.7 , pp. 1087-1093
    • Elovic, R.P.1    Hipp, J.A.2    Hayes, W.C.3
  • 29
    • 0034193247 scopus 로고    scopus 로고
    • Bone wound healing after maxillary molar extraction in ovariectomized aged rats: quantitative backscattered electron image analysis
    • Shimizu M., Furuya R., Kawawa T., and Sasaki T. Bone wound healing after maxillary molar extraction in ovariectomized aged rats: quantitative backscattered electron image analysis. Anat Rec 259 1 (2000) 76-85
    • (2000) Anat Rec , vol.259 , Issue.1 , pp. 76-85
    • Shimizu, M.1    Furuya, R.2    Kawawa, T.3    Sasaki, T.4
  • 30
    • 0029315967 scopus 로고
    • The effect of ovariectomy on the healing tooth socket of the rat
    • Hsieh Y.D., Devlin H., and McCord F. The effect of ovariectomy on the healing tooth socket of the rat. Arch Oral Biol 40 6 (1995) 529-531
    • (1995) Arch Oral Biol , vol.40 , Issue.6 , pp. 529-531
    • Hsieh, Y.D.1    Devlin, H.2    McCord, F.3
  • 31
    • 3342897648 scopus 로고    scopus 로고
    • Bone healing in osteoporotic female rats following intra-alveolar grafting of bioactive glass
    • Teófilo J.M., Brentegani L.G., and Lamano-Carvalho T.L. Bone healing in osteoporotic female rats following intra-alveolar grafting of bioactive glass. Arch Oral Biol 49 9 (2004) 755-762
    • (2004) Arch Oral Biol , vol.49 , Issue.9 , pp. 755-762
    • Teófilo, J.M.1    Brentegani, L.G.2    Lamano-Carvalho, T.L.3
  • 32
    • 27744599521 scopus 로고    scopus 로고
    • Circulating osteoprotegerin and receptor activator for nuclear factor kappaB ligand: clinical utility in metabolic bone disease assessment
    • Rogers A., and Eastell R. Circulating osteoprotegerin and receptor activator for nuclear factor kappaB ligand: clinical utility in metabolic bone disease assessment. J Clin Endocrinol Metab 90 11 (2005) 6323-6331
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.11 , pp. 6323-6331
    • Rogers, A.1    Eastell, R.2
  • 33
    • 34548454049 scopus 로고    scopus 로고
    • Biology of RANK, RANKL, and osteoprotegerin
    • Boyce B.F., and Xing L. Biology of RANK, RANKL, and osteoprotegerin. Arthritis Res Ther 9 Suppl 1 (2007) S1
    • (2007) Arthritis Res Ther , vol.9 , Issue.SUPPL. 1
    • Boyce, B.F.1    Xing, L.2
  • 34
    • 73949119177 scopus 로고    scopus 로고
    • Haidar ZS, Hamdy RC, Tabrizian M. Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part A. Current challenges in BMP delivery. Biotechnol Lett 2009 [Epub ahead of print].
    • Haidar ZS, Hamdy RC, Tabrizian M. Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part A. Current challenges in BMP delivery. Biotechnol Lett 2009 [Epub ahead of print].
  • 35
    • 69249088910 scopus 로고    scopus 로고
    • Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model
    • Young S., Patel Z.S., Kretlow J.D., Murphy M.B., Mountziaris P.M., Baggett L.S., et al. Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model. Tissue Eng Part A 15 9 (2009) 2347-2362
    • (2009) Tissue Eng Part A , vol.15 , Issue.9 , pp. 2347-2362
    • Young, S.1    Patel, Z.S.2    Kretlow, J.D.3    Murphy, M.B.4    Mountziaris, P.M.5    Baggett, L.S.6
  • 36
    • 0032079445 scopus 로고    scopus 로고
    • Osteoprotegerin deficient mice develop early onset osteoporosis and arterial calcification
    • Bucay N., Sarosi I., Dunstan C.R., Morony S., Tarpley J., Capparelli C., et al. Osteoprotegerin deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev 12 9 (1998) 1260-1268
    • (1998) Genes Dev , vol.12 , Issue.9 , pp. 1260-1268
    • Bucay, N.1    Sarosi, I.2    Dunstan, C.R.3    Morony, S.4    Tarpley, J.5    Capparelli, C.6
  • 37
    • 0031765480 scopus 로고    scopus 로고
    • A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro
    • Quinn J.M., Elliott J., Gillespie M.T., and Martin T.J. A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro. Endocrinology 139 10 (1998) 4424-4427
    • (1998) Endocrinology , vol.139 , Issue.10 , pp. 4424-4427
    • Quinn, J.M.1    Elliott, J.2    Gillespie, M.T.3    Martin, T.J.4
  • 38
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
    • Yasuda E, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, Mochizuki S, et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 1998;95(7):3597-602.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.7 , pp. 3597-3602
    • Yasuda, E.1    Shima, N.2    Nakagawa, N.3    Yamaguchi, K.4    Kinosaki, M.5    Mochizuki, S.6
  • 39
    • 0034455667 scopus 로고    scopus 로고
    • Clinical review 114: hot topic The role of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in the pathogenesis and treatment of metabolic bone diseases
    • Hofbauer L.C., and Heufelder A.E. Clinical review 114: hot topic The role of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in the pathogenesis and treatment of metabolic bone diseases. J Clin Endocrinol Metab 85 7 (2000) 2355-2363
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.7 , pp. 2355-2363
    • Hofbauer, L.C.1    Heufelder, A.E.2
  • 40
    • 0037398261 scopus 로고    scopus 로고
    • Role of RANK ligand in mediating increased bone resorption in early posmenopausal women
    • Eghbali-Fatourechi G., Klosla S., Sanyal A., Boyle W.J., Lacey D.L., and Riggs B.L. Role of RANK ligand in mediating increased bone resorption in early posmenopausal women. J Clin Invest 111 8 (2003) 1221-1230
    • (2003) J Clin Invest , vol.111 , Issue.8 , pp. 1221-1230
    • Eghbali-Fatourechi, G.1    Klosla, S.2    Sanyal, A.3    Boyle, W.J.4    Lacey, D.L.5    Riggs, B.L.6
  • 41
    • 0033581952 scopus 로고    scopus 로고
    • Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
    • Kong Y.Y., Feige U., Sarosi I., Bolon B., Tafuri A., Morony S., et al. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 402 6759 (1999) 304-309
    • (1999) Nature , vol.402 , Issue.6759 , pp. 304-309
    • Kong, Y.Y.1    Feige, U.2    Sarosi, I.3    Bolon, B.4    Tafuri, A.5    Morony, S.6
  • 42
    • 0033805254 scopus 로고    scopus 로고
    • Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection
    • Teng Y.T., Nguyen H., Gao X., Kong Y.Y., Gorczynski R.M., Singh B., et al. Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection. J Clin Invest 106 6 (2000) R59-R67
    • (2000) J Clin Invest , vol.106 , Issue.6
    • Teng, Y.T.1    Nguyen, H.2    Gao, X.3    Kong, Y.Y.4    Gorczynski, R.M.5    Singh, B.6
  • 43
    • 0035723970 scopus 로고    scopus 로고
    • Osteoprotegerin inhibits artery calcification induced by warfarin and by vitamin D
    • Price P.A., June H.H., Buckley J.R., and Williamson Mk. Osteoprotegerin inhibits artery calcification induced by warfarin and by vitamin D. Arterioscler Thromb Vasc Biol 21 10 (2001) 1610-1616
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , Issue.10 , pp. 1610-1616
    • Price, P.A.1    June, H.H.2    Buckley, J.R.3    Williamson, Mk.4
  • 44
    • 1542379067 scopus 로고    scopus 로고
    • Disabling of receptor activator of nuclear factor-kappaB (RANK) receptor complex by novel osteoprotegerin-like peptidomimetics restores bone loss in vivo
    • Cheng X., Kinosaki M., Takami M., Choi Y., Zhang H., and Murali R. Disabling of receptor activator of nuclear factor-kappaB (RANK) receptor complex by novel osteoprotegerin-like peptidomimetics restores bone loss in vivo. J Biol Chem 279 9 (2004) 8269-8277
    • (2004) J Biol Chem , vol.279 , Issue.9 , pp. 8269-8277
    • Cheng, X.1    Kinosaki, M.2    Takami, M.3    Choi, Y.4    Zhang, H.5    Murali, R.6
  • 45
    • 0034608813 scopus 로고    scopus 로고
    • Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression
    • Shevde N.K., Bendixen A.C., Dienger K.M., and Pike J.W. Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression. Proc Natl Acad Sci USA 97 14 (2000) 7829-7834
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.14 , pp. 7829-7834
    • Shevde, N.K.1    Bendixen, A.C.2    Dienger, K.M.3    Pike, J.W.4
  • 46
    • 0033304632 scopus 로고    scopus 로고
    • Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells
    • Hofbauer L.C., Khosla S., Dunstan C.R., Lancey D.L., Spelsberg T.C., and Riggs B.L. Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology 140 9 (1999) 4367-4370
    • (1999) Endocrinology , vol.140 , Issue.9 , pp. 4367-4370
    • Hofbauer, L.C.1    Khosla, S.2    Dunstan, C.R.3    Lancey, D.L.4    Spelsberg, T.C.5    Riggs, B.L.6
  • 47
    • 72649091661 scopus 로고    scopus 로고
    • Effects of alendronate treatment on serum levels of osteoprotegerin and total receptor activator of nuclear factor kappaB in women with postmenopausal osteoporosis
    • Epub ahead of print
    • Reyes-García R, Muñoz-Torres M, García DF, Mezquita-Raya P, García Salcedo JA, de Dios Luna J. Effects of alendronate treatment on serum levels of osteoprotegerin and total receptor activator of nuclear factor kappaB in women with postmenopausal osteoporosis. Menopause 2009 [Epub ahead of print].
    • (2009) Menopause
    • Reyes-García, R.1    Muñoz-Torres, M.2    García, D.F.3    Mezquita-Raya, P.4    García Salcedo, J.A.5    de Dios Luna, J.6
  • 48
    • 0033815281 scopus 로고    scopus 로고
    • Force-induced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression
    • Kobayashi Y., Hashimoto F., Miyamoto H., Kanaoka K., Miyazaki-Kawashita Y., Nakashima T., et al. Force-induced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression. J Bone Miner Res 15 10 (2000) 1924-1934
    • (2000) J Bone Miner Res , vol.15 , Issue.10 , pp. 1924-1934
    • Kobayashi, Y.1    Hashimoto, F.2    Miyamoto, H.3    Kanaoka, K.4    Miyazaki-Kawashita, Y.5    Nakashima, T.6
  • 49
    • 12144286198 scopus 로고    scopus 로고
    • Novel and selective small molecule stimulators of osteoprotegerin expression inhibit bone resorption
    • Onyia J.E., Galvin R.J., Ma Y.L., Halladay D.L., Miles R.R., Yang X., et al. Novel and selective small molecule stimulators of osteoprotegerin expression inhibit bone resorption. J Pharmacol Exp Ther 309 1 (2004) 369-379
    • (2004) J Pharmacol Exp Ther , vol.309 , Issue.1 , pp. 369-379
    • Onyia, J.E.1    Galvin, R.J.2    Ma, Y.L.3    Halladay, D.L.4    Miles, R.R.5    Yang, X.6


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