Effect of an estrogen-deficient state and its therapy on bone loss resulting from an experimental periodontitis in rats

Journal of Periodontal Research

Volumn 39, Issue 2, 2004, Pages 107-110

  Duarte, Poliana Mendes ^a   Gonçalves, Patricia Furtado ^a   Sallum, Antonio Wilson ^a   Sallum, Enilson Antonio ^a   Casati, Marcio Zaffalon ^a   Nociti Jr , Francisco Humberto ^a,b  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Calcitonin; Estrogen; Osteoporosis; Periodontitis

Indexed keywords

CALCITONIN; ESTROGEN; ALKALINE PHOSPHATASE; CALCIUM; ESTRADIOL;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BLOOD ANALYSIS; BONE METABOLISM; CALCIUM BLOOD LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; ESTROGEN DEFICIENCY; ESTROGEN THERAPY; EXPERIMENTAL MODEL; INTERMETHOD COMPARISON; NONHUMAN; OSTEOLYSIS; OVARIECTOMY; PERIODONTITIS; RANDOMIZATION; RAT; STATISTICAL SIGNIFICANCE; TOOTH PLAQUE; TREATMENT OUTCOME; ANALYSIS OF VARIANCE; ANIMAL; BLOOD; FEMALE; IMAGE PROCESSING; INSTRUMENTATION; LIGATION; PATHOLOGY; STATISTICAL ANALYSIS; TIME; WISTAR RAT;

ALKALINE PHOSPHATASE; ALVEOLAR BONE LOSS; ANALYSIS OF VARIANCE; ANIMALS; CALCITONIN; CALCIUM; DENTAL PLAQUE; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; FEMALE; IMAGE PROCESSING, COMPUTER-ASSISTED; LIGATION; MATCHED-PAIR ANALYSIS; OVARIECTOMY; PERIODONTITIS; RANDOM ALLOCATION; RATS; RATS, WISTAR; TIME FACTORS;

EID: 4143065666     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2004.00714.x     Document Type: Article

References (17)

1. Page RC, Schroeder HE. Pathogenesis of inflammatory periodontal disease. A summary of current work. Lab Invest 1976;34:235-249.
2. Genco RJ. Current view of risk factors for periodontal disease. J Periodontol 1996;67:1041-1049.
3. Harrison JE. Osteoporosis. In: Tam CS, Heersche JNM, Murray TM, eds. Metabolic bone diseases: cellular and tissue mechanisms. Boca Raton: CRC Press, 1989: 240-267.
4. Wronski TJ, Dann LM, Qi H et al. Skeletal effects of withdrawal of estrogen and diphosphonate treatment in ovariectomized rats. Calcif Tissue Int 1993;53:210-216.
5. Wronski TJ, Yen C-F, Burton KW et al. Skeletal effects of calcitonin in ovariectomized rats. Endocrinology 1991;129:2246-2250.
6. Kribbs PJ. Comparison of mandibular bone in normal and osteoporotic women. J Prosthet Dent 1990;63:218-222.
7. Wactawski-Wende J, Grossi SG, Trevisan M et al. The role of osteopenia in oral bone loss and periodontal disease. J Periodontol 1996;67:1076-1084.
8. Klemetti E, Collin H-L, Forss H et al. Mineral status of skeleton and advanced periodontal disease. J Clin Periodontol 1994;21:184-188.
9. Johnson RB, Gilbert JA, Cooper RC et al. Alveolar bone loss one year following ovariectomy in sheep. J Periodontol 1997;68:864-871.
10. Simonet WS, Lacey DL, Dunstan CR et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997;89:309-319.
11. Teng Y-TA, Nguyen H, Gao X et al. Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection. J Clin Invest 2000;106:R59-R67.
12. Lindberg MK, Erlandsson M, Alatalo SL et al. Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the OPG/RANKL (osteoprotegerin/receptor activator of NF-kappa B ligand) ratio and serum interleukin-6 in male mice. J Endocrinol 2001;171:425-433.
13. Kawamoto S, Ejiri S, Hoshi K et al. Immunolocalization of osteoclast differentiation factor in rat periodontium. Arch Oral Biol 2002;47:55-58.
14. Vaananen HK, Harkonen PL. Estrogen and bone metabolism. Maturitas 1996;23:65.
15. Shen Y, Li M, Wronski TJ. Skeletal effects of calcitonin treatment and withdrawal in ovariectomized rats. Calcif Tissue Int 1996;58:263-267.
16. Gruber HE, Ivey JL, Baylink DJ et al. Long-term calcitonin therapy in post-menopausal osteoporosis. Metabolism 1984;33:295-303.
17. Messer HH, Copp DH. Changes in response to calcitonin following prolonged administration to intact rats. Proc Soc Exp Biol Med 1974;146:643-647.