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Volumn 11, Issue 23, 2009, Pages 5478-5481

Modular construction of 2-substituted benzo[b]furans from 1,2-Dichlorovinyl ethers

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; BENZOFURAN DERIVATIVE; CHLORINATED HYDROCARBON; ETHER DERIVATIVE; VINYL DERIVATIVE;

EID: 72449211741     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol902307m     Document Type: Article
Times cited : (43)

References (47)
  • 24
    • 40949124680 scopus 로고    scopus 로고
    • Lautens has devised a related method for the synthesis of indoles and benzofurans. See: (a) Fang, Y.-Q.; Lautens, M. J. Org. Chem. 2008, 73, 538.
    • (2008) J. Org. Chem. , vol.73 , pp. 538
    • Fang, Y.-Q.1    Lautens, M.2
  • 28
    • 72449181221 scopus 로고    scopus 로고
    • Xantphos was an equally effective ligand in these reactions, but we chose the less-expensive DPEphos for the bulk of our work.
    • Xantphos was an equally effective ligand in these reactions, but we chose the less-expensive DPEphos for the bulk of our work.
  • 30
    • 72449209594 scopus 로고    scopus 로고
    • Schmidt et al. (ref 9c) have reported an analogous Pd-catalyzed coupling to a 1,2-dichlorovinyl ether. Curiously, they obtained specific C-2 alkynylation.
    • Schmidt et al. (ref 9c) have reported an analogous Pd-catalyzed coupling to a 1,2-dichlorovinyl ether. Curiously, they obtained specific C-2 alkynylation.
  • 41
    • 72449186943 scopus 로고    scopus 로고
    • The preparation and characterization of 28-30 are described in the Supporting Information.
    • The preparation and characterization of 28-30 are described in the Supporting Information.
  • 42
    • 72449124584 scopus 로고    scopus 로고
    • The N-BOC enamides underwent Suzuki coupling but failed to cyclize under the one-pot conditions. When monoarylated N-BOC enamides were separately subjected to Pd-catalyzed cyclization conditions, cyclization did occur, but substantial loss of the BOC group was observed. See the Supporting Information for experimental details.
    • The N-BOC enamides underwent Suzuki coupling but failed to cyclize under the one-pot conditions. When monoarylated N-BOC enamides were separately subjected to Pd-catalyzed cyclization conditions, cyclization did occur, but substantial loss of the BOC group was observed. See the Supporting Information for experimental details.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.