E-1,2-Dichlorovinyl ethers as irreversible protease inhibitors

Tetrahedron Letters

Volumn 45, Issue 8, 2004, Pages 1751-1753

  Schmidt, Boris ^a   Ehlert, Dennis K ^a   Braun, Hannes A ^a  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Enol ether; Protease

Indexed keywords

ETHER DERIVATIVE; PROTEINASE INHIBITOR;

AMINO TERMINAL SEQUENCE; AQUEOUS SOLUTION; ARTICLE; CHEMICAL REACTION; DIASTEREOISOMER; DRUG SYNTHESIS; HYDROLYSIS; PH MEASUREMENT;

EID: 0842305132     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2003.12.088     Document Type: Article

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5. f : 0.88 (Alox 60-N-E) to give the ether as a colorless oil (82.3 mg, 39%).
6. Moyano A., Charbonnier F., Greene A.E. J. Org. Chem. 52:1987;2919-2922.