Th2 but not Th1 immune bias results in altered lung functions in a murine model of pulmonary Cryptococcus neoformans infection

Infection and Immunity

Volumn 77, Issue 12, 2009, Pages 5389-5399

  Jain, Aditya V ^a   Zhang, Yanmei ^b   Fields, W Bradley ^a,b   McNamara, David A ^a   Choe, Mun Y ^a   Chen, Gwo Hsiao ^a,b   Erb Downward, John ^b   Osterholzer, John J ^a,b   Toews, Galen B ^a,b   Huffnagle, Gary B ^b,c   Olszewski, Michal A ^a,b  

^a VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4;

AIRWAY RESISTANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CELLULAR IMMUNITY; CONTROLLED STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; EOSINOPHIL; FEMALE; FUNGAL STRAIN; FUNGUS CULTURE; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOPHENOTYPING; INFLAMMATION; INOCULATION; LUNG FUNCTION; LUNG INFECTION; MACROPHAGE; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INFECTION; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

ANIMALS; BRAIN; COLONY COUNT, MICROBIAL; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; FEMALE; IMMUNOGLOBULIN E; INFLAMMATION; INFLAMMATION MEDIATORS; LEUKOCYTES; LUNG; LUNG DISEASES, FUNGAL; MICE; MICE, INBRED BALB C; RATS; RESPIRATORY FUNCTION TESTS; TH1 CELLS; TH2 CELLS;

EID: 72449193573     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00809-09     Document Type: Article

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