Impaired cardiac functional reserve and left ventricular hypertrophy in adult sheep after prenatal dexamethasone exposure

Circulation Research

Volumn 89, Issue 7, 2001, Pages 623-629

  Dodic, Miodrag ^a   Samuel, Chrishan ^a   Moritz, Karen ^a   Wintour, E Marelyn ^a   Morgan, John ^b   Grigg, Leeanne ^b   Wong, James ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Dexamethasone; Hypertension; Left ventricular hypertrophy; Sheep

Indexed keywords

COLLAGEN; DEXAMETHASONE; DOBUTAMINE; POLYGELINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART MUSCLE CONTRACTILITY; HEART OUTPUT; HYPERTENSION; M MODE ECHOCARDIOGRAPHY; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL;

EID: 0035964915     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh1901.097086     Document Type: Article

References (36)

1. Fetal, infant, and childhood growth are predictors of coronary heart disease, diabetes, and hypertension in adult men and women
2. Birth weight, weight at one year, and left ventricular mass in adult life
3. Growth in utero, adult blood pressure, and arterial compliance
4. Weights at birth and in early infancy, systolic pressure and left ventricular structure in subjects aged 8 to 24 years
5. The role of size at birth and postnatal catch-up growth in determining systolic blood pressure: A systematic review of the literature
6. In utero programming of chronic disease
7. An early prenatal exposure to excess glucocorticoid leads to hypertensive offspring in sheep
8. Altered cardiovascular haemodynamics and baroreceptor-heart rate reflex in adult sheep after prenatal exposure to dexamethasone
9. Intrauterine nutrition: Its importance during critical periods for cardiovascular and endocrine development
10. Glucocorticoids, 11β-hydroxysteroid dehydrogenase, and fetal programming
11. Intrauterine programming of cardiovascular disease by maternal nutritional status
12. Hypertension induced by fetal exposure to a maternal low-protein diet, in the rat, is prevented by pharmacological blockade of maternal glucocorticoid synthesis
13. Coronary heart disease after prenatal exposure to the Dutch famine, 1944-45
14. Plasma lipid profiles in adults after prenatal exposure to the Dutch famine
15. Obesity at the age of 50 y in men and women exposed to famine prenatally
16. Weanling rats exposed to maternal low-protein diets during discrete periods of gestation exhibit differing severity of hypertension
17. Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension
18. Problems in echocardiographic determinations: Echocardiographic-angiographic correlations in the presence or absence of asynergy
19. The effect of relaxin on collagen metabolism in the nonpregnant rat pubic symphysis: The influence of estrogen and progesterone in regulating relaxin activity
20. Two improved and simplified methods for the spectrophotometric determination of hydroxyproline
21. Collagen in the normal and hypertrophied human ventricle
22. The estimation of two collagens from human dermis by interrupted gel electrophoresis
23. Multiple comparison procedures updated
24. The myocardial β-adrenergic system in spontaneously hypertensive heart failure (SHHF) rats
25. Continuous relation between left ventricular mass and cardiovascular risk in essential hypertension
26. Why is left ventricular hypertrophy so predictive of morbidity and mortality?
27. Left ventricular geometry as an independent predictor for extracardiac target organ damage in essential hypertension
28. Echocardiographic determination of left ventricular mass in man
29. Left ventricular hypertrophy in hypertension: Stimuli, patterns, and consequences
30. 3 human skin collagen: Release by pepsin digestion and preponderance in fetal life
31. The athlete's heart: A meta-analysis of cardiac structure and function
32. Risk mechanisms in hypertensive heart disease
33. Aldosterone and the heart
34. Cardiac aldosterone production and ventricular remodeling
35. Relation of left ventricular diastolic properties to systolic function in arterial hypertension
36. Diastolic dysfunction precedes myocardial hypertrophy in the development of hypertension