메뉴 건너뛰기




Volumn 7, Issue 23, 2009, Pages 4918-4923

Peptide thioester synthesis through N→S acyl-transfer: Application to the synthesis of a β-defensin

Author keywords

[No Author keywords available]

Indexed keywords

ACYL TRANSFER; DEFENSINS; MINI-PROTEINS; NATIVE CHEMICAL LIGATION; PEPTIDE THIOESTERS; THIOESTERS;

EID: 72449169005     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b913886b     Document Type: Article
Times cited : (36)

References (19)
  • 13
    • 58149471991 scopus 로고    scopus 로고
    • For clarity BME (pH8.0), BME/TFA and MAA in Fig. 2a, and 10% AcOH and 10% MBA (Fig. 2b) are given non-zero values for peptide thioester synthesis and peptide hydrolysis respectively, despite zero values being recorded
    • J. Kang J. P. Richardson D. Macmillan Chem. Commun. 2009 4 407
    • (2009) Chem. Commun. , Issue.4 , pp. 407
    • Kang, J.1    Richardson, J.P.2    MacMillan, D.3
  • 19
    • 43749116000 scopus 로고    scopus 로고
    • The chemotaxis graph shows the number of CCR6-expressing HEK293 cells migrated towards the peptide. Data is presented as numerical mean ± SD, of the number of cells per high power field (HPF) (x40 magnification). Each assay was repeated 3 times, in triplicate, with 3 fields of view per repeat. Asterisks represent significant chemoattraction from control at p<0.001 (***). Results are approximately equivalent to CCR6 chemokine ligand CCL20 (MIP-3α) and murine β-defensin Defb14 (Data not shown) Minimum bactericidal concentrations are the lowest concentrations of peptide required for 99.99% of bacteria to die
    • K. Taylor D. J. Clarke B. McCullough W. Chin E. Seo D. Yang J. Oppenheim D. Uhrin J. R. W. Govan D. J. Campopiano D. MacMillan P. Barran J. R. Dorin J. Biol. Chem. 2008 283 6631
    • (2008) J. Biol. Chem. , vol.283 , pp. 6631
    • Taylor, K.1    Clarke, D.J.2    McCullough, B.3    Chin, W.4    Seo, E.5    Yang, D.6    Oppenheim, J.7    Uhrin, D.8    Govan, J.R.W.9    Campopiano, D.J.10    MacMillan, D.11    Barran, P.12    Dorin, J.R.13


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.