Imaging applications of nanotechnology in cancer

Targeted Oncology

Volumn 4, Issue 3, 2009, Pages 169-181

  Gunasekera, U Ayanthi ^a   Pankhurst, Quentin A ^b   Douek, Michael ^c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b DAVY FARADAY RESEARCH LABORATORY   (United Kingdom)

^c GUY S HOSPITAL   (United Kingdom)

Author keywords

Cancer; Imaging; Nanoparticles; Nanotechnology

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; BOMBESIN; BOMBESIN RECEPTOR; C DOT; CARBON NANOTUBE; CONTRAST MEDIUM; CORE SHELL SILICA PARTICLE; DENDRIMER; DOXORUBICIN; GADOLINIUM; GADOLINIUM PENTETATE; GOLD NANOPARTICLE; LIPOSOME; LOW DENSITY LIPOPROTEIN; MACROGOL; MAGNETITE; MUCIN 1; NANOCOATING; NANOPARTICLE; NANOROD; NANOSHELL; POLYAMIDOAMINE; POLYSORBATE; QUANTUM DOT; SILICON DIOXIDE; SUPERPARAMAGNETIC IRON OXIDE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; TRASTUZUMAB; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; BRAIN CANCER; BREAST CANCER; CANCER DIAGNOSIS; CELL LABELING; COLON CANCER; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; DRUG CONJUGATION; DRUG TARGETING; FLUORESCENCE MICROSCOPY; HUMAN; ISOTOPE LABELING; LYMPH NODE METASTASIS; MULTIPHOTON MICROSCOPY; NANOIMAGING; NANOPROBE; NANOTECHNOLOGY; NEOPLASM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PANCREAS CANCER; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROSTATE CANCER; REVIEW; TREATMENT RESPONSE;

ANIMALS; CLINICAL TRIALS AS TOPIC; DIAGNOSTIC IMAGING; HUMANS; NANOMEDICINE; NANOTECHNOLOGY; NEOPLASMS;

EID: 72449165355     PISSN: 17762596     EISSN: 1776260X     Source Type: Journal    
DOI: 10.1007/s11523-009-0118-9     Document Type: Review

References (70)

1. Feynman RP (1959) There's plenty of room at the bottom. Presented at the Annual Meeting of the American Physical Society, December 29, 1959, California Institute of Technology, Pasadena, CA). http://www.zyvex.com/nanotech/feynman. html
2. N Sanvicens MP Marco 2008 Multifunctional nanoparticles-properties and prospects for their use in human medicine Trends Biotechnol 26 8 425 433 10.1016/j.tibtech.2008.04.005 18514941
3. M Longmire PL Choyke H Kobayashi 2008 Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats Nanomed 3 5 703 717 10.2217/17435889.3.5.703 18817471
4. H Maeda 2001 The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting Adv Enzyme Regul 41 189 207 10.1016/S0065-2571(00)00013-3 11384745 (Pubitemid 32520323)
5. RK Jain 2008 Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer Nat Rev Cancer 8 4 309 316 10.1038/nrc2346 18337733
6. MV Yezhelyev X Gao Y Xing A Al-Hajj S Nie RM O'Regan 2006 Emerging use of nanoparticles in diagnosis and treatment of breast cancer Lancet Oncol 7 8 657 667 10.1016/S1470-2045(06)70793-8 16887483 (Pubitemid 44143778)
7. C Loo A Lowery N Halas J West R Drezek 2005 Immunotargeted nanoshells for integrated cancer imaging and therapy Nano Lett 5 4 709 711 10.1021/nl050127s 15826113 (Pubitemid 40609745)
8. JR McCarthy R Weissleder 2008 Multifunctional magnetic nanoparticles for targeted imaging and therapy Adv Drug Deliv Rev 60 11 1241 1251 10.1016/j.addr.2008.03.014 18508157
9. M Ferrari 2005 Cancer nanotechnology: opportunities and challenges Nat Rev Cancer 5 3 161 171 10.1038/nrc1566 15738981 (Pubitemid 40314948)
10. J Yang CH Lee HJ Ko JS Suh HG Yoon K Lee, et al. 2007 Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer Angew Chem Int Ed Engl 46 46 8836 8839 10.1002/anie.200703554 17943947 (Pubitemid 350207937)
11. Z Medarova W Pham C Farrar V Petkova A Moore 2007 In vivo imaging of siRNA delivery and silencing in tumors Nat Med 13 3 372 377 10.1038/nm1486 17322898 (Pubitemid 46376679)
12. LR Hirsch AM Gobin AR Lowery F Tam RA Drezek NJ Halas, et al. 2006 Metal nanoshells Ann Biomed Eng 34 1 15 22 10.1007/s10439-005-9001-8 16528617
13. LR Hirsch RJ Stafford JA Bankson SR Sershen B Rivera RE Price, et al. 2003 Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance Proc Natl Acad Sci USA 100 23 13549 13554 10.1073/pnas.2232479100 14597719 (Pubitemid 37444779)
14. JR McCarthy KA Kelly EY Sun R Weissleder 2007 Targeted delivery of multifunctional magnetic nanoparticles Nanomed 2 2 153 167 10.2217/17435889.2.2. 153 17716118 (Pubitemid 46850565)
15. P Dinh C Sotiriou MJ Piccart 2007 The evolution of treatment strategies: aiming at the target Breast 16 Suppl 2 S10 S16 10.1016/j.breast.2007.07.032 17764940
16. S Nie Y Xing GJ Kim JW Simons 2007 Nanotechnology applications in cancer Annu Rev Biomed Eng 9 257 288 10.1146/annurev.bioeng.9.060906.152025 17439359 (Pubitemid 350246658)
17. R Kumar I Roy TY Ohulchanskyy LN Goswami AC Bonoiu EJ Bergey, et al. 2008 Covalently dye-linked, surface-controlled, and bioconjugated organically modified silica nanoparticles as targeted probes for optical imaging ACS Nano 2 3 449 456 10.1021/nn700370b 19206569
18. U Menon IJ Jacobs 2000 Recent developments in ovarian cancer screening Curr Opin Obstet Gynecol 12 1 39 42 10.1097/00001703-200002000-00007 10752515 (Pubitemid 32260287)
19. X Wang L Yang ZG Chen DM Shin 2008 Application of nanotechnology in cancer therapy and imaging CA Cancer J Clin 58 2 97 110 10.3322/CA.2007.0003 18227410
20. MG Harisinghani J Barentsz PF Hahn WM Deserno S Tabatabaei CH van de Kaa, et al. 2003 Noninvasive detection of clinically occult lymph-node metastases in prostate cancer N Engl J Med 348 25 2491 2499 10.1056/NEJMoa022749 12815134 (Pubitemid 36706536)
21. MG Harisinghani R Weissleder 2004 Sensitive, noninvasive detection of lymph node metastases PLoSMed 1 3 e66
22. MN Rhyner AM Smith X Gao H Mao L Yang S Nie 2006 Quantum dots and multifunctional nanoparticles: new contrast agents for tumor imaging Nanomed 1 2 209 217 10.2217/17435889.1.2.209 17716110
23. AM Smith H Duan AM Mohs S Nie 2008 Bioconjugated quantum dots for in vivo molecular and cellular imaging Adv Drug Deliv Rev 60 11 1226 1240 10.1016/j.addr.2008.03.015 18495291
24. Y Nagasaki T Ishii Y Sunaga Y Watanabe H Otsuka K Kataoka 2004 Novel molecular recognition via fluorescent resonance energy transfer using a biotin-PEG/polyamine stabilized CdS quantum dot Langmuir 20 15 6396 6400 10.1021/la036034c 15248728
25. TJ Fountaine SM Wincovitch DH Geho SH Garfield S Pittaluga 2006 Multispectral imaging of clinically relevant cellular targets in tonsil and lymphoid tissue using semiconductor quantum dots Mod Pathol 19 9 1181 1191 10.1038/modpathol.3800628 16778828 (Pubitemid 44268188)
26. LA Bentolila Y Ebenstein S Weiss 2009 Quantum dots for in vivo small-animal imaging J Nucl Med 50 4 493 496 10.2967/jnumed.108.053561 19289434
27. WJ Mulder R Koole RJ Brandwijk G Storm PT Chin GJ Strijkers, et al. 2006 Quantum dots with a paramagnetic coating as a bimodal molecular imaging probe Nano Lett 6 1 1 6 10.1021/nl051935m 16402777 (Pubitemid 43166093)
28. S Santra H Yang JT Stanley PH Holloway BM Moudgil G Walter, et al. 2005 Rapid and effective labeling of brain tissue using TAT-conjugated CdS:Mn/ZnS quantum dots Chem Commun (Camb) 25 3144 3146 10.1039/b503234b (Pubitemid 41002376)
29. AM Derfus AA Chen DH Min E Ruoslahti SN Bhatia 2007 Targeted quantum dot conjugates for siRNA delivery Bioconjug Chem 18 5 1391 1396 10.1021/bc060367e 17630789 (Pubitemid 47464045)
30. EB Voura JK Jaiswal H Mattoussi SM Simon 2004 Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy Nat Med 10 9 993 998 10.1038/nm1096 15334072 (Pubitemid 39273742)
31. C Kirchner T Liedl S Kudera T Pellegrino A Munoz Javier HE Gaub, et al. 2005 Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles Nano Lett 5 2 331 338 10.1021/nl047996m 15794621 (Pubitemid 40308295)
32. RS Yang LW Chang JP Wu MH Tsai HJ Wang YC Kuo, et al. 2007 Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment Environ Health Perspect 115 9 1339 1343 17805425
33. J Choi AA Burns RM Williams Z Zhou A Flesken-Nikitin WR Zipfel, et al. 2007 Core-shell silica nanoparticles as fluorescent labels for nanomedicine J Biomed Opt 12 6 064007 10.1117/1.2823149 18163823
34. D Kim S Park JH Lee YY Jeong S Jon 2007 Antibiofouling polymer-coated gold nanoparticles as a contrast agent for in vivo X-ray computed tomography imaging J Am Chem Soc 129 24 7661 7665 10.1021/ja071471p 17530850 (Pubitemid 46981930)
35. Z Liu W Cai L He N Nakayama K Chen X Sun, et al. 2007 In vivo biodistribution and highly efficient tumor targeting of carbon nanotubes in mice Nat Nanotechnol 2 1 47 52 10.1038/nnano.2006.170 18654207 (Pubitemid 46210038)
36. M Hamoudeh MA Kamleh R Diab H Fessi 2008 Radionuclides delivery systems for nuclear imaging and radiotherapy of cancer Adv Drug Deliv Rev 60 12 1329 1346 10.1016/j.addr.2008.04.013 18562040
37. GH Zoarski JR Parker RB Lufkin HR Harnsberger CH Rhoda 1992 Efficacy of gadoteridol for magnetic resonance imaging of extracranial head and neck pathology Invest Radiol 27 Suppl 1 S53 S57 1506154
38. S Vitols 1991 Uptake of low-density lipoprotein by malignant cells-possible therapeutic applications Cancer Cells 3 12 488 495 1840290
39. IR Corbin H Li J Chen S Lund-Katz R Zhou JD Glickson, et al. 2006 Low-density lipoprotein nanoparticles as magnetic resonance imaging contrast agents Neoplasia 8 6 488 498 10.1593/neo.05835 16820095 (Pubitemid 44035333)
40. DA Tomalia LA Reyna S Svenson 2007 Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging Biochem Soc Trans 35 Pt 1 61 67 17233602
41. H Kobayashi S Kawamoto Y Sakai PL Choyke RA Star MW Brechbiel, et al. 2004 Lymphatic drainage imaging of breast cancer in mice by micro-magnetic resonance lymphangiography using a nano-size paramagnetic contrast agent J Natl Cancer Inst 96 9 703 708 15126607
42. X Shi S Wang S Meshinchi ME Van Antwerp X Bi I Lee, et al. 2007 Dendrimer-entrapped gold nanoparticles as a platform for cancer-cell targeting and imaging Small 3 7 1245 1252 10.1002/smll.200700054 17523182
43. A Vogel 1997 Nonlinear absorption: intraocular microsurgery and laser lithotripsy Phys Med Biol 42 5 895 912 10.1088/0031-9155/42/5/011 9172266 (Pubitemid 27263507)
44. DL Thorek AK Chen J Czupryna A Tsourkas 2006 Superparamagnetic iron oxide nanoparticle probes for molecular imaging Ann Biomed Eng 34 1 23 38 10.1007/s10439-005-9002-7 16496086
45. MK Yu YY Jeong J Park S Park JW Kim JJ Min, et al. 2008 Drug-loaded superparamagnetic iron oxide nanoparticles for combined cancer imaging and therapy in vivo Angew Chem Int Ed Engl 47 29 5362 5365 10.1002/anie.200800857 18551493
46. KJ Landmark S Dimaggio J Ward C Kelly S Vogt S Hong, et al. 2008 Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers ACS Nano 2 4 773 783 10.1021/nn800034w 19206610
47. AK Gupta RR Naregalkar VD Vaidya M Gupta 2007 Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications Nanomed 2 1 23 39 10.2217/17435889.2.1.23 17716188 (Pubitemid 46845774)
48. H Lee MK Yu S Park S Moon JJ Min YY Jeong, et al. 2007 Thermally cross-linked superparamagnetic iron oxide nanoparticles: synthesis and application as a dual imaging probe for cancer in vivo J Am Chem Soc 129 42 12739 12745 10.1021/ja072210i 17892287 (Pubitemid 350004485)
49. DG Stupack DA Cheresh 2004 Integrins and angiogenesis Curr Top Dev Biol 64 207 238 10.1016/S0070-2153(04)64009-9 15563949 (Pubitemid 39752398)
50. MD Pierschbacher E Ruoslahti 1984 Variants of the cell recognition site of fibronectin that retain attachment-promoting activity Proc Natl Acad Sci USA 81 19 5985 5988 10.1073/pnas.81.19.5985 6237366 (Pubitemid 15219582)
51. X Montet K Montet-Abou F Reynolds R Weissleder L Josephson 2006 Nanoparticle imaging of integrins on tumor cells Neoplasia 8 3 214 222 10.1593/neo.05769 16611415 (Pubitemid 43671237)
52. M Liong J Lu M Kovochich T Xia SG Ruehm AE Nel, et al. 2008 Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery ACS Nano 2 5 889 896 10.1021/nn800072t 19206485
53. P Tallury K Payton S Santra 2008 Silica-based multimodal/multifunctional nanoparticles for bioimaging and biosensing applications Nanomed 3 4 579 592 10.2217/17435889.3.4.579 18694319
54. CW Lu Y Hung JK Hsiao M Yao TH Chung YS Lin, et al. 2007 Bifunctional magnetic silica nanoparticles for highly efficient human stem cell labeling Nano Lett 7 1 149 154 10.1021/nl0624263 17212455 (Pubitemid 46225844)
55. JH Lee YW Jun SI Yeon JS Shin J Cheon 2006 Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma Angew Chem Int Ed Engl 45 48 8160 8162 10.1002/anie.200603052 17103471 (Pubitemid 44974152)
56. T Joshi M Douek QA Pankhurst S Hattersley A Brazdeikis M Hall-Craggs E De Vita A Bainbridge R Sainsbury A Sharma 2007 Magnetic nanoparticles for detecting sentinel lymph nodes Eur J Surg Oncol 33 9 1135
57. Statistical Information Team (2009) Cancer research UK, breast cancer. http://info.cancerresearchuk.org/cancerstats/
58. S Kim YT Lim EG Soltesz AM De Grand J Lee A Nakayama, et al. 2004 Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping Nat Biotechnol 22 1 93 97 10.1038/nbt920 14661026 (Pubitemid 38057962)
59. JH Lee YM Huh YW Jun JW Seo JT Jang HT Song, et al. 2007 Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging Nat Med 13 1 95 99 10.1038/nm1467 17187073 (Pubitemid 46067392)
60. V Bagalkot L Zhang E Levy-Nissenbaum S Jon PW Kantoff R Langer, et al. 2007 Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer Nano Lett 7 10 3065 3070 10.1021/nl071546n 17854227 (Pubitemid 350132931)
61. C Wang J Chen T Talavage J Irudayaraj 2009 Gold nanorod/Fe3O4 nanoparticle "nano-pearl-necklaces" for simultaneous targeting, dual-mode imaging, and photothermal ablation of cancer cells Angew Chem Int Ed Engl 48 15 2759 2763 10.1002/anie.200805282 19283813
62. Z Medarova L Rashkovetsky P Pantazopoulos A Moore 2009 Multiparametric monitoring of tumor response to chemotherapy by noninvasive imaging Cancer Res 69 3 1182 1189 10.1158/0008-5472.CAN-08-2001 19141648
63. P Fortina LJ Kricka DJ Graves J Park T Hyslop F Tam, et al. 2007 Applications of nanoparticles to diagnostics and therapeutics in colorectal cancer Trends Biotechnol 25 4 145 152 10.1016/j.tibtech.2007.02.005 17316852 (Pubitemid 46413367)
64. R Weissleder K Kelly EY Sun T Shtatland L Josephson 2005 Cell-specific targeting of nanoparticles by multivalent attachment of small molecules Nat Biotechnol 23 11 1418 1423 10.1038/nbt1159 16244656 (Pubitemid 41679395)
65. R Weissleder CH Tung U Mahmood A Bogdanov Jr 1999 In vivo imaging of tumors with protease-activated near-infrared fluorescent probes Nat Biotechnol 17 4 375 378 10.1038/7933 10207887 (Pubitemid 29166041)
66. TP Thomas AK Patri A Myc MT Myaing JY Ye TB Norris, et al. 2004 In vitro targeting of synthesized antibody-conjugated dendrimer nanoparticles Biomacromolecules 5 6 2269 2274 10.1021/bm049704h 15530041 (Pubitemid 39585279)
67. O Veiseh C Sun J Gunn N Kohler P Gabikian D Lee, et al. 2005 Optical and MRI multifunctional nanoprobe for targeting gliomas Nano Lett 5 6 1003 1008 10.1021/nl0502569 15943433 (Pubitemid 40925409)
68. X Montet R Weissleder L Josephson 2006 Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas Bioconjug Chem 17 4 905 911 10.1021/bc060035+ 16848396 (Pubitemid 44162607)
69. T Tanaka P Decuzzi M Cristofanilli JH Sakamoto E Tasciotti FM Robertson, et al. 2009 Nanotechnology for breast cancer therapy Biomed Microdevices 11 1 49 63 10.1007/s10544-008-9209-0 18663578
70. TF Massoud SS Gambhir 2003 Molecular imaging in living subjects: seeing fundamental biological processes in a new light Genes Dev 17 5 545 580 10.1101/gad.1047403 12629038 (Pubitemid 36307540)