메뉴 건너뛰기




Volumn 111, Issue 8, 2008, Pages 3968-3977

Thalidomide for treatment of multiple myeloma: 10 years later

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALLOPURINOL; ANTICOAGULANT AGENT; BENZODIAZEPINE DERIVATIVE; CHLORPROMAZINE; CORTICOSTEROID; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; LOW MOLECULAR WEIGHT HEPARIN; MELPHALAN; METHYLPREDNISOLONE; NEUROLEPTIC AGENT; OPIATE DERIVATIVE; PAMIDRONIC ACID; PHENYTOIN; PREDNISOLONE; PREDNISONE; RESERPINE; SULFONAMIDE; THALIDOMIDE; VINCRISTINE; WARFARIN; ANTINEOPLASTIC AGENT;

EID: 43249097561     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2007-10-117457     Document Type: Review
Times cited : (280)

References (78)
  • 1
    • 0029548149 scopus 로고    scopus 로고
    • Immunomodulation by thalidomide: Systemic review of the literature and of unpublished observations
    • Zwingenberger K, Wnendt S. Immunomodulation by thalidomide: systemic review of the literature and of unpublished observations. J Inflamm. 1996;46:177-211.
    • (1996) J Inflamm , vol.46 , pp. 177-211
    • Zwingenberger, K.1    Wnendt, S.2
  • 2
    • 0031985198 scopus 로고    scopus 로고
    • Multiple myeloma: Increasing evidence for a multi- step transformation process
    • Hallek M, Leif Bergsagel P, Anderson KC. Multiple myeloma: increasing evidence for a multi- step transformation process. Blood. 1998;91:3-21.
    • (1998) Blood , vol.91 , pp. 3-21
    • Hallek, M.1    Leif Bergsagel, P.2    Anderson, K.C.3
  • 3
    • 0033105537 scopus 로고    scopus 로고
    • Cell adhesion mediated drug resistance (CAM- DR): Role of integrins and resistance to apopto- sis in human myeloma cell lines
    • Damiano JS, Cress AE, Hazlehurst LA, et al. Cell adhesion mediated drug resistance (CAM- DR): role of integrins and resistance to apopto- sis in human myeloma cell lines. Blood. 1999; 93:1658-1667.
    • (1999) Blood , vol.93 , pp. 1658-1667
    • Damiano, J.S.1    Cress, A.E.2    Hazlehurst, L.A.3
  • 4
    • 0034903286 scopus 로고    scopus 로고
    • Thalidomide in multiple myeloma, myelodysplastic syndromes and histiocytosis: Analysis of clinical results and of surrogate angiogenesis markers
    • Bertolini F, Mingrone W, Alietti A, et al. Thalidomide in multiple myeloma, myelodysplastic syndromes and histiocytosis: analysis of clinical results and of surrogate angiogenesis markers. Ann Oncol. 2001;12:987-990.
    • (2001) Ann Oncol , vol.12 , pp. 987-990
    • Bertolini, F.1    Mingrone, W.2    Alietti, A.3
  • 7
    • 0033630619 scopus 로고    scopus 로고
    • Metabolism of thalidomide in human microsomes, cloned human cytochrome P-450 isozymes and Hansen's disease patients
    • Teo S, Sabourin P, O'Brien K, et al. Metabolism of thalidomide in human microsomes, cloned human cytochrome P-450 isozymes and Hansen's disease patients. J Biochem Mol Toxicol. 2000;14:140-147.
    • (2000) J Biochem Mol Toxicol , vol.14 , pp. 140-147
    • Teo, S.1    Sabourin, P.2    O'Brien, K.3
  • 8
    • 0034822474 scopus 로고    scopus 로고
    • Thalidomide is distributed into human semen after oral dosing
    • Teo SK, Harden JL, Burke AB, et al. Thalidomide is distributed into human semen after oral dosing. Drug Metab Dispos. 2001;29:1355-1357.
    • (2001) Drug Metab Dispos , vol.29 , pp. 1355-1357
    • Teo, S.K.1    Harden, J.L.2    Burke, A.B.3
  • 9
    • 0032748385 scopus 로고    scopus 로고
    • Antitumor activity of thalidomide in refractory multiple myeloma
    • Singhal S, Mehta J, Desikan R, et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med. 1999;341:1565-1571.
    • (1999) N Engl J Med , vol.341 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 10
    • 0035880229 scopus 로고    scopus 로고
    • Ex-tented survival in advanced and refractory multiple myeloma after single-agent thalidomide: Identification of prognostic factors in a phase 2 study of 169 patients
    • Barlogie B, Desikan R, Eddlemor P, et al. Ex-tented survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients. Blood. 2001;98:492-494.
    • (2001) Blood , vol.98 , pp. 492-494
    • Barlogie, B.1    Desikan, R.2    Eddlemor, P.3
  • 11
    • 33750631112 scopus 로고    scopus 로고
    • Long-term results of thalidomide in refractory and relapsed multiple myeloma with emphasis on response duration
    • Cibeira MT, Rosinol L, Ramiro L, et al. Long-term results of thalidomide in refractory and relapsed multiple myeloma with emphasis on response duration. Eur J Haematol. 2006;77:486-492.
    • (2006) Eur J Haematol , vol.77 , pp. 486-492
    • Cibeira, M.T.1    Rosinol, L.2    Ramiro, L.3
  • 12
    • 33644898842 scopus 로고    scopus 로고
    • A systematic review of phase II trials of thalidomide monotherapy in patients with relapsed or refractory multiple myeloma
    • Glasmacher A, Hahn A, Hoffmann F, et al. A systematic review of phase II trials of thalidomide monotherapy in patients with relapsed or refractory multiple myeloma. Br J Hematol. 2005;132:584-593.
    • (2005) Br J Hematol , vol.132 , pp. 584-593
    • Glasmacher, A.1    Hahn, A.2    Hoffmann, F.3
  • 13
    • 3242763046 scopus 로고    scopus 로고
    • Extramedullary multiple myeloma escapes the effect of thalidomide
    • Rosinol L, Cibeira MT, Blade J, et al Extramedullary multiple myeloma escapes the effect of thalidomide. Haematologica. 2004;89:832-836.
    • (2004) Haematologica , vol.89 , pp. 832-836
    • Rosinol, L.1    Cibeira, M.T.2    Blade, J.3
  • 14
    • 34147110072 scopus 로고    scopus 로고
    • Amulti-center prospective randomised study testing non inferiority of thalidomide 100 mg/day as compared with 400 mg/day in patients with refractory/relapsed multiple myeloma: Results of the final analysis of the IFM 01-02 study [abstract]
    • Yakoub-Agha I, Doyen C, Hulin C, et al. Amulti-center prospective randomised study testing non inferiority of thalidomide 100 mg/day as compared with 400 mg/day in patients with refractory/relapsed multiple myeloma: results of the final analysis of the IFM 01-02 study [abstract]. J Clin Oncol. 2006;24:7520.
    • (2006) J Clin Oncol , vol.24 , pp. 7520
    • Yakoub-Agha, I.1    Doyen, C.2    Hulin, C.3
  • 15
    • 0037208595 scopus 로고    scopus 로고
    • Thalidomide alone or with dexamethasone for previously untreated multiple myeloma
    • Weber D, Rankin K, Gavino M, et al. Thalidomide alone or with dexamethasone for previously untreated multiple myeloma. J Clin Oncol. 2003;21:16-19.
    • (2003) J Clin Oncol , vol.21 , pp. 16-19
    • Weber, D.1    Rankin, K.2    Gavino, M.3
  • 16
    • 17944376919 scopus 로고    scopus 로고
    • Thalidomide for previously untreated indolent or smoldering multiple myeloma
    • Rajkumar SV, Dispenzieri A, Fonseca R, et al. Thalidomide for previously untreated indolent or smoldering multiple myeloma. Leukemia. 2001;15:1274-1276.
    • (2001) Leukemia , vol.15 , pp. 1274-1276
    • Rajkumar, S.V.1    Dispenzieri, A.2    Fonseca, R.3
  • 17
    • 4544386351 scopus 로고    scopus 로고
    • Palumbo A, Bertola A, Falco P, et al. Efficacy of low dose thalidomide as first salvage regimen in multiple myeloma. Hemat J. 2004;5:318-324.
    • Palumbo A, Bertola A, Falco P, et al. Efficacy of low dose thalidomide as first salvage regimen in multiple myeloma. Hemat J. 2004;5:318-324.
  • 18
    • 0035018156 scopus 로고    scopus 로고
    • Low-dose thalidomide plus dexamethasone is an effective therapy for advanced myeloma
    • Palumbo A, Giaccone L, Bertola A, et al. Low-dose thalidomide plus dexamethasone is an effective therapy for advanced myeloma. Haematologica. 2001;86:399-403.
    • (2001) Haematologica , vol.86 , pp. 399-403
    • Palumbo, A.1    Giaccone, L.2    Bertola, A.3
  • 19
    • 0034899464 scopus 로고    scopus 로고
    • Thalidomide and dexamethasone combination or refractory multiple myeloma
    • Dimopoulos MA, Zervas K, Kouvatseas G, et al. Thalidomide and dexamethasone combination or refractory multiple myeloma. Ann Oncol. 2001;12:991-995.
    • (2001) Ann Oncol , vol.12 , pp. 991-995
    • Dimopoulos, M.A.1    Zervas, K.2    Kouvatseas, G.3
  • 20
    • 61849178582 scopus 로고    scopus 로고
    • Fermand JP, Jaccard A, Macro M, et al. A randomized comparison of dexamethasone + thalidomide (Dex/Tal) vs Dex + Placebo (Dex/P) in patients (pts) with relapsing multiple myeloma (MM) [abstract]. Blood. 2006;108:Abstract 3563.
    • Fermand JP, Jaccard A, Macro M, et al. A randomized comparison of dexamethasone + thalidomide (Dex/Tal) vs Dex + Placebo (Dex/P) in patients (pts) with relapsing multiple myeloma (MM) [abstract]. Blood. 2006;108:Abstract 3563.
  • 21
    • 4544321241 scopus 로고    scopus 로고
    • Thalidomide plus oral melphalan compared with thalidomide alone for advanced multiple myeloma
    • Offidani M, Corvatta L, Marconi M, et al. Thalidomide plus oral melphalan compared with thalidomide alone for advanced multiple myeloma. Hematol J. 2004;5:312-317.
    • (2004) Hematol J , vol.5 , pp. 312-317
    • Offidani, M.1    Corvatta, L.2    Marconi, M.3
  • 22
    • 33644834155 scopus 로고    scopus 로고
    • Intravenous melphalan, thalidomide and prednisone in refractory and relapsed multiple myeloma
    • Palumbo A, Avonto I, Bruno B, et al. Intravenous melphalan, thalidomide and prednisone in refractory and relapsed multiple myeloma. Eur J Hematol. 2006;76:273-277.
    • (2006) Eur J Hematol , vol.76 , pp. 273-277
    • Palumbo, A.1    Avonto, I.2    Bruno, B.3
  • 23
    • 0036909461 scopus 로고    scopus 로고
    • Use of melphalan, thalidomide and dexamethasone in treatment of refractory and relapsed multiple myeloma
    • Srakovic G, Elson P, Trebisky B, et al. Use of melphalan, thalidomide and dexamethasone in treatment of refractory and relapsed multiple myeloma. Med Oncol. 2002;19:219-226.
    • (2002) Med Oncol , vol.19 , pp. 219-226
    • Srakovic, G.1    Elson, P.2    Trebisky, B.3
  • 24
    • 32544447241 scopus 로고    scopus 로고
    • Low-dose thalidomide with pegylated liposomal doxorubicin and high-dose dexamethasone for relapsed/refractory multiple myeloma: A prospective, multicenter, phase II study
    • Offidani M, Corvatta L, Marconi M, et al. Low-dose thalidomide with pegylated liposomal doxorubicin and high-dose dexamethasone for relapsed/refractory multiple myeloma: a prospective, multicenter, phase II study. Haematologica. 2006;91:133-136.
    • (2006) Haematologica , vol.91 , pp. 133-136
    • Offidani, M.1    Corvatta, L.2    Marconi, M.3
  • 25
    • 33745628076 scopus 로고    scopus 로고
    • Phase 2 study of pegylated liposomal doxorubicin, vincristine, decreased-frequency dexamethasone, and thalidomide in newly diagnosed and relapsedrefractory multiple myeloma
    • Hussein MA, Baz R, Srkalovic G, et al. Phase 2 study of pegylated liposomal doxorubicin, vincristine, decreased-frequency dexamethasone, and thalidomide in newly diagnosed and relapsedrefractory multiple myeloma. Mayo Clin Proc. 2006;81:889-895.
    • (2006) Mayo Clin Proc , vol.81 , pp. 889-895
    • Hussein, M.A.1    Baz, R.2    Srkalovic, G.3
  • 26
    • 21344459018 scopus 로고    scopus 로고
    • Low dose thalidomide in combination with oral weekly cyclophosphamide and pulsed dexamethasone is a well tolerated and effective regimen in patients with relapsed and refractory multiple myeloma
    • Kyriakou C, Thomson K, D'Sa S, et al. Low dose thalidomide in combination with oral weekly cyclophosphamide and pulsed dexamethasone is a well tolerated and effective regimen in patients with relapsed and refractory multiple myeloma. Br J Hematol. 2005;129:763-770.
    • (2005) Br J Hematol , vol.129 , pp. 763-770
    • Kyriakou, C.1    Thomson, K.2    D'Sa, S.3
  • 27
    • 11144356289 scopus 로고    scopus 로고
    • Pulsed cyclophosphamide, thalidomide and dexamethasone: An oral regiment for previously treated patients with multiple myeloma
    • Dimopoulos MA, Hamilos G, Zomas A, et al. Pulsed cyclophosphamide, thalidomide and dexamethasone: an oral regiment for previously treated patients with multiple myeloma. Hematol J. 2004;5:112-117.
    • (2004) Hematol J , vol.5 , pp. 112-117
    • Dimopoulos, M.A.1    Hamilos, G.2    Zomas, A.3
  • 28
    • 1942522741 scopus 로고    scopus 로고
    • The oral combination of thalidomide, cyclophosphamide and dexamethasone is effective in relapsed/refractory multiple myeloma
    • Garcia-Sanz R, Gonzalez-Porras JR, Hernandez JM, et al. The oral combination of thalidomide, cyclophosphamide and dexamethasone is effective in relapsed/refractory multiple myeloma. Leukemia. 2004;18:856-863.
    • (2004) Leukemia , vol.18 , pp. 856-863
    • Garcia-Sanz, R.1    Gonzalez-Porras, J.R.2    Hernandez, J.M.3
  • 29
    • 0042161862 scopus 로고    scopus 로고
    • Hyperfrac- tionated cyclophosphamide in combination with pulsed dexamethasone and thalidomide (HyperCTD) in primary refractory or relapsed multiple myeloma
    • Kropff MH, Lang N, Bisping G, et al. Hyperfrac- tionated cyclophosphamide in combination with pulsed dexamethasone and thalidomide (HyperCTD) in primary refractory or relapsed multiple myeloma. Br J Haematol. 2003;122:607-616.
    • (2003) Br J Haematol , vol.122 , pp. 607-616
    • Kropff, M.H.1    Lang, N.2    Bisping, G.3
  • 30
    • 0037396605 scopus 로고    scopus 로고
    • Thalidomide as initial therapy for early-stage myeloma
    • Rajkumar SV, Gertz MA, Lacy MQ, et al. Thalidomide as initial therapy for early-stage myeloma. Leukemia. 2003;17:775-779.
    • (2003) Leukemia , vol.17 , pp. 775-779
    • Rajkumar, S.V.1    Gertz, M.A.2    Lacy, M.Q.3
  • 31
    • 33644831033 scopus 로고    scopus 로고
    • Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group
    • Rajkumar SV, Blood E, Vesole D, et al. Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol. 2006;24:431-436.
    • (2006) J Clin Oncol , vol.24 , pp. 431-436
    • Rajkumar, S.V.1    Blood, E.2    Vesole, D.3
  • 32
    • 22044452126 scopus 로고    scopus 로고
    • Superiority of thalidomide and dexamethasone over vincristine-doxorubicin-dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma
    • Cavo M, Zamagni E, Tosi P, et al. Superiority of thalidomide and dexamethasone over vincristine-doxorubicin-dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma. Blood. 2005;106:35-39.
    • (2005) Blood , vol.106 , pp. 35-39
    • Cavo, M.1    Zamagni, E.2    Tosi, P.3
  • 33
    • 61849119985 scopus 로고    scopus 로고
    • Macro M, Divine M, Uzunhan Y, et al. Dexamethasone+thalidomide (dex/thal) compared to VAD as a pre-transplant treatment in newly diagnosed multiple myeloma (MM): a randomized trial [abstract]. Blood. 2006;108:Abstract 57.
    • Macro M, Divine M, Uzunhan Y, et al. Dexamethasone+thalidomide (dex/thal) compared to VAD as a pre-transplant treatment in newly diagnosed multiple myeloma (MM): a randomized trial [abstract]. Blood. 2006;108:Abstract 57.
  • 34
    • 0036843032 scopus 로고    scopus 로고
    • Combination therapy with thalidomide plus dexametha- sone for newly diagnosed myeloma
    • Rajkumar SV, Hayman S, Gertz MA, et al. Combination therapy with thalidomide plus dexametha- sone for newly diagnosed myeloma. J Clin Oncol. 2002;20:3419-3423.
    • (2002) J Clin Oncol , vol.20 , pp. 3419-3423
    • Rajkumar, S.V.1    Hayman, S.2    Gertz, M.A.3
  • 36
    • 22044451992 scopus 로고    scopus 로고
    • Thalidomide-dexamethasone as primary therapy for advanced multiple myeloma
    • Wang M, Weber D, Delasalle K, Alexanian R. Thalidomide-dexamethasone as primary therapy for advanced multiple myeloma. Am J Hematol. 2005;79:194-197.
    • (2005) Am J Hematol , vol.79 , pp. 194-197
    • Wang, M.1    Weber, D.2    Delasalle, K.3    Alexanian, R.4
  • 37
    • 33644843725 scopus 로고    scopus 로고
    • Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: Randomised controlled trial
    • Palumbo A, Bringhen S, Caravita T, et al. Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial. Lancet. 2006;367:825-831.
    • (2006) Lancet , vol.367 , pp. 825-831
    • Palumbo, A.1    Bringhen, S.2    Caravita, T.3
  • 38
    • 34848833957 scopus 로고    scopus 로고
    • Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): A randomised trial
    • Facon T, Mary J, Hulin C, et al. Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial. Lancet. 2007;370:1209-1218.
    • (2007) Lancet , vol.370 , pp. 1209-1218
    • Facon, T.1    Mary, J.2    Hulin, C.3
  • 39
    • 61849120625 scopus 로고    scopus 로고
    • Hulin C, Facon T, Rodon P, et al. Melphalan-Prednisone-Thalidomide (MP-T) demonstrates a significant survival advantage in elderly patients >75 years with multiple myeloma compared with Melphalan and Prednisone (MP) in a randomized, double blind, placebo-controlled trial IFM 01-01 [abstract]. Blood. 2007;110:Abstract 75.
    • Hulin C, Facon T, Rodon P, et al. Melphalan-Prednisone-Thalidomide (MP-T) demonstrates a significant survival advantage in elderly patients >75 years with multiple myeloma compared with Melphalan and Prednisone (MP) in a randomized, double blind, placebo-controlled trial IFM 01-01 [abstract]. Blood. 2007;110:Abstract 75.
  • 40
    • 9144226204 scopus 로고    scopus 로고
    • Primary treatment of multiple myeloma with thalidomide, vincristine, liposomal doxorubicin and dexamethasone (T-VAD doxil): A phase II multi-center study
    • Zervas K, Dimopoulus MA, Hatzicharissi E, et al. Primary treatment of multiple myeloma with thalidomide, vincristine, liposomal doxorubicin and dexamethasone (T-VAD doxil): a phase II multi-center study. Ann Oncol. 2004;15:134-138.
    • (2004) Ann Oncol , vol.15 , pp. 134-138
    • Zervas, K.1    Dimopoulus, M.A.2    Hatzicharissi, E.3
  • 41
    • 0035927983 scopus 로고    scopus 로고
    • Deep venous thrombosis and thalidomide therapy for multiple myeloma
    • Osman K, Comenzo R, Rajkumar SV. Deep venous thrombosis and thalidomide therapy for multiple myeloma. N Engl J Med. 2001;344:1951.
    • (2001) N Engl J Med , vol.344 , pp. 1951
    • Osman, K.1    Comenzo, R.2    Rajkumar, S.V.3
  • 42
    • 19944430150 scopus 로고    scopus 로고
    • Thalidomide in combination with vincristine, epirubicin and dexamethasone (VED) for previously untreated patients with multiple myeloma
    • Schutt P, Ebeling P, Buttkereit U, et al. Thalidomide in combination with vincristine, epirubicin and dexamethasone (VED) for previously untreated patients with multiple myeloma. Eur J Haematol. 2005;74:40-46.
    • (2005) Eur J Haematol , vol.74 , pp. 40-46
    • Schutt, P.1    Ebeling, P.2    Buttkereit, U.3
  • 43
    • 28544436819 scopus 로고    scopus 로고
    • The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma
    • Baz R, Li L, Kottke-Marchant K, et al. The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma. Mayo Clin Proc. 2005;80:1549-1551.
    • (2005) Mayo Clin Proc , vol.80 , pp. 1549-1551
    • Baz, R.1    Li, L.2    Kottke-Marchant, K.3
  • 44
    • 33749361262 scopus 로고    scopus 로고
    • Thalidomide, dexamethasone and pegylated liposomal doxorubicin (ThaDD) for patients older than 65 years with newly diagnosed multiple myeloma
    • Offidani M, Corvatta L, Piersantelli MN, et al. Thalidomide, dexamethasone and pegylated liposomal doxorubicin (ThaDD) for patients older than 65 years with newly diagnosed multiple myeloma. Blood. 2006;108:2159-2164.
    • (2006) Blood , vol.108 , pp. 2159-2164
    • Offidani, M.1    Corvatta, L.2    Piersantelli, M.N.3
  • 45
    • 34548173936 scopus 로고    scopus 로고
    • VAD-doxil versus VAD-doxil plus thalidomide as initial treatment for multiple myeloma: Results of a multi-center randomized trial of the Greek myeloma study group
    • Zervas K, Mihou D, Katodritou E, et al. VAD-doxil versus VAD-doxil plus thalidomide as initial treatment for multiple myeloma: results of a multi-center randomized trial of the Greek myeloma study group. Ann Oncol. 2007;18:1369-1375.
    • (2007) Ann Oncol , vol.18 , pp. 1369-1375
    • Zervas, K.1    Mihou, D.2    Katodritou, E.3
  • 46
    • 19944368366 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism with low molecular-weight heparin in patients with multiple myeloma treated with thalidomide and chemotherapy
    • Minnema MC, Breitkreutz I, Auwerda Jja, et al. Prevention of venous thromboembolism with low molecular-weight heparin in patients with multiple myeloma treated with thalidomide and chemotherapy. Leukemia. 2004;18:2044-2046.
    • (2004) Leukemia , vol.18 , pp. 2044-2046
    • Minnema, M.C.1    Breitkreutz, I.2    Jja, A.3
  • 47
    • 33751081803 scopus 로고    scopus 로고
    • The combination of cyclophosphomide, thalidomide and dexamethasone is an effective alternative to cyclophosphamide-vincristine-doxorubicin-methylprednisolone as induction chemotherapy prior to autologous transplantation for multiple myeloma: A case-matched analysis
    • Wu P, Davies FE, Horton C, et al. The combination of cyclophosphomide, thalidomide and dexamethasone is an effective alternative to cyclophosphamide-vincristine-doxorubicin-methylprednisolone as induction chemotherapy prior to autologous transplantation for multiple myeloma: a case-matched analysis. Leuk Lymphoma. 2006;47:2335-2338.
    • (2006) Leuk Lymphoma , vol.47 , pp. 2335-2338
    • Wu, P.1    Davies, F.E.2    Horton, C.3
  • 48
    • 33745749976 scopus 로고    scopus 로고
    • Combination chemotherapy with cyclophosphamide, thalidomide and dexamethasone for patients with refractory, newly diagnosed or relapsed myeloma
    • Sidra G, Williams CD, Russel NH, et al. Combination chemotherapy with cyclophosphamide, thalidomide and dexamethasone for patients with refractory, newly diagnosed or relapsed myeloma. Haematologica. 2006;91:862-863.
    • (2006) Haematologica , vol.91 , pp. 862-863
    • Sidra, G.1    Williams, C.D.2    Russel, N.H.3
  • 49
    • 33644833147 scopus 로고    scopus 로고
    • Thalidomide and hematopoietic-cell transplantation for multiple myeloma
    • Barlogie B, Tricot G, Anaissie E, et al. Thalidomide and hematopoietic-cell transplantation for multiple myeloma. N Engl J Med. 2006;354:1021-1030.
    • (2006) N Engl J Med , vol.354 , pp. 1021-1030
    • Barlogie, B.1    Tricot, G.2    Anaissie, E.3
  • 50
    • 0037103292 scopus 로고    scopus 로고
    • Thrombogenic activity of doxorubicin in myeloma patients receiving thalidomide: Implications for therapy
    • Zangari M, Siegel E, Barlogie B, et al. Thrombogenic activity of doxorubicin in myeloma patients receiving thalidomide: implications for therapy. Blood. 2002;100:1168-1171.
    • (2002) Blood , vol.100 , pp. 1168-1171
    • Zangari, M.1    Siegel, E.2    Barlogie, B.3
  • 51
    • 4544332965 scopus 로고    scopus 로고
    • Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: Effects of prophylactic and therapeutic anticoagulation
    • Zangari M, Barlogie B, Anaissie E, et al. Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: effects of prophylactic and therapeutic anticoagulation. Br J Haematol. 2004;126:715-721.
    • (2004) Br J Haematol , vol.126 , pp. 715-721
    • Zangari, M.1    Barlogie, B.2    Anaissie, E.3
  • 52
    • 33748314823 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, placebo-controlled trial of thalidomide plus dexamethasone versus dexamethasone alone as initial therapy for newly diagnosed multiple myeloma [abstract]
    • Rajkumar SV, Hussein M, Catalano J, et al. A multicenter, randomized, double-blind, placebo-controlled trial of thalidomide plus dexamethasone versus dexamethasone alone as initial therapy for newly diagnosed multiple myeloma [abstract]. J Clin Oncol. 2006;24:7517.
    • (2006) J Clin Oncol , vol.24 , pp. 7517
    • Rajkumar, S.V.1    Hussein, M.2    Catalano, J.3
  • 53
    • 34249673492 scopus 로고    scopus 로고
    • Thalidomide in newly diagnosed multiple myeloma: Influence of thalidomide treatment on peripheral blood stem cell collection yield
    • Breitkreutz I, Lokhorst HM, Raab MS, et al. Thalidomide in newly diagnosed multiple myeloma: influence of thalidomide treatment on peripheral blood stem cell collection yield. Leukemia. 2007; 21:1294-1299.
    • (2007) Leukemia , vol.21 , pp. 1294-1299
    • Breitkreutz, I.1    Lokhorst, H.M.2    Raab, M.S.3
  • 54
    • 33751164196 scopus 로고    scopus 로고
    • Maintenance therapy with thalidomide improves survival in multiple myeloma patients
    • Attal M, Harousseau JL, Leyvraz S, et al. Maintenance therapy with thalidomide improves survival in multiple myeloma patients. Blood. 2006;108:3289-3294.
    • (2006) Blood , vol.108 , pp. 3289-3294
    • Attal, M.1    Harousseau, J.L.2    Leyvraz, S.3
  • 55
    • 61849176875 scopus 로고    scopus 로고
    • Spencer A, Prince HM, Roberts A, et al. Thalidomide improve survivals when use after ASCT [abstract]. Hematologica. 2007;92:Abstract S7b.
    • Spencer A, Prince HM, Roberts A, et al. Thalidomide improve survivals when use after ASCT [abstract]. Hematologica. 2007;92:Abstract S7b.
  • 56
    • 41349095233 scopus 로고    scopus 로고
    • Single autologous stem cell transplantation followed by maintenance therapy with thalidomide is superior to double autologous transplantation in multiple myeloma: Results of a multicentre randomized clinical trial
    • Abdelkefi A, Ladeb S, Torjman L, et al. Single autologous stem cell transplantation followed by maintenance therapy with thalidomide is superior to double autologous transplantation in multiple myeloma: results of a multicentre randomized clinical trial. Blood. 2008;111:1805-1810.
    • (2008) Blood , vol.111 , pp. 1805-1810
    • Abdelkefi, A.1    Ladeb, S.2    Torjman, L.3
  • 57
    • 61849156690 scopus 로고    scopus 로고
    • Cavo M, Testoni N, Terragna C, et al. Up-front thalidomide-dexamethasone (thal) and double autologous transplantation (double TX) for multiple myeloma: comparison with double TX without added thalidomide and prognostic implications of chromosome 13 deletion and traslocation t(4;14) [abstract]. Blood. 2006;108:Abstract 3081.
    • Cavo M, Testoni N, Terragna C, et al. Up-front thalidomide-dexamethasone (thal) and double autologous transplantation (double TX) for multiple myeloma: comparison with double TX without added thalidomide and prognostic implications of chromosome 13 deletion and traslocation t(4;14) [abstract]. Blood. 2006;108:Abstract 3081.
  • 58
    • 34547909238 scopus 로고    scopus 로고
    • Time to first progression, but not b2-microglobulin, predicts outcome in myeloma patients who received thalidomide as salvage therapy
    • Palumbo A, Bringhen S, Falco P, et al. Time to first progression, but not b2-microglobulin, predicts outcome in myeloma patients who received thalidomide as salvage therapy. Cancer. 2007;110:824-829.
    • (2007) Cancer , vol.110 , pp. 824-829
    • Palumbo, A.1    Bringhen, S.2    Falco, P.3
  • 59
    • 0026561179 scopus 로고
    • Thalidomide in human immunodeficiency virus (HIV) patients: A review of safety considerations
    • Gunzler V. Thalidomide in human immunodeficiency virus (HIV) patients: a review of safety considerations. Drug Safety. 1992;7:116-134.
    • (1992) Drug Safety , vol.7 , pp. 116-134
    • Gunzler, V.1
  • 60
    • 0033770171 scopus 로고    scopus 로고
    • Assessment of the in vitro and in vivo genotoxicity of thalomid (thalidomide)
    • Teo S, Morgan M, Stirling D, et al. Assessment of the in vitro and in vivo genotoxicity of thalomid (thalidomide). Teratog Carcinog Mutagen. 2000;20:301-311.
    • (2000) Teratog Carcinog Mutagen , vol.20 , pp. 301-311
    • Teo, S.1    Morgan, M.2    Stirling, D.3
  • 61
    • 0031735722 scopus 로고    scopus 로고
    • Does thalidomide cause second generation birth defects?
    • Smithells D. Does thalidomide cause second generation birth defects? Drug Safety. 1998;19:339-341.
    • (1998) Drug Safety , vol.19 , pp. 339-341
    • Smithells, D.1
  • 62
    • 0036526384 scopus 로고    scopus 로고
    • Activated protein C resistance in the absence of factor V Leiden mutation is a common finding in multiple myeloma and is associated with an increased risk of thrombotic complications
    • Zangari M, Saghafifar F, Anaissie E, et al. Activated protein C resistance in the absence of factor V Leiden mutation is a common finding in multiple myeloma and is associated with an increased risk of thrombotic complications. Blood Coagul Fibrinolysis. 2002;13:187-192.
    • (2002) Blood Coagul Fibrinolysis , vol.13 , pp. 187-192
    • Zangari, M.1    Saghafifar, F.2    Anaissie, E.3
  • 63
    • 4444308010 scopus 로고    scopus 로고
    • Modification of thrombomodulin plasma levels in refractory myeloma patients during treatment with thalidomide and dexamethasone
    • Corso A, Lorenzi A, Terulla V, et al. Modification of thrombomodulin plasma levels in refractory myeloma patients during treatment with thalidomide and dexamethasone. Ann Hematol. 2004;83:588-591.
    • (2004) Ann Hematol , vol.83 , pp. 588-591
    • Corso, A.1    Lorenzi, A.2    Terulla, V.3
  • 64
    • 4644316831 scopus 로고    scopus 로고
    • Thalidomide protects endothelial cells from doxorubicin-induced apoptosis but alters cell morphology
    • Kaushal V, Kaushal GP, Melkaveri SN, et al. Thalidomide protects endothelial cells from doxorubicin-induced apoptosis but alters cell morphology. J Thromb Haemost. 2004;2:327- 334.
    • (2004) J Thromb Haemost , vol.2 , pp. 327-334
    • Kaushal, V.1    Kaushal, G.P.2    Melkaveri, S.N.3
  • 65
    • 16244363678 scopus 로고    scopus 로고
    • Markers of endothelial and haemostatic function in the treatment of relapsed myeloma with the immuno-modulatory agent actimid (CC-4047) and their relationship with venous thrombosis
    • Streetly M, Hunt BJ, Parmar K, et al. Markers of endothelial and haemostatic function in the treatment of relapsed myeloma with the immuno-modulatory agent actimid (CC-4047) and their relationship with venous thrombosis. Eur J Haematol. 2005;74:293-296.
    • (2005) Eur J Haematol , vol.74 , pp. 293-296
    • Streetly, M.1    Hunt, B.J.2    Parmar, K.3
  • 66
    • 5344258973 scopus 로고    scopus 로고
    • Adverse effects of thalidomide administration in patients with neoplastic disease
    • Dimopoulos MA, Eleutherakis V. Adverse effects of thalidomide administration in patients with neoplastic disease. Am J Med. 2004;117:508-515.
    • (2004) Am J Med , vol.117 , pp. 508-515
    • Dimopoulos, M.A.1    Eleutherakis, V.2
  • 67
    • 11144354418 scopus 로고    scopus 로고
    • Bradycardia during therapy for multiple myeloma with tha- lidomide
    • Fahdi IE, Gaddam V, Saucedo JF, et al. Bradycardia during therapy for multiple myeloma with tha- lidomide. Am J Cardiol. 2004;93:1052-1055.
    • (2004) Am J Cardiol , vol.93 , pp. 1052-1055
    • Fahdi, I.E.1    Gaddam, V.2    Saucedo, J.F.3
  • 68
    • 33749051832 scopus 로고    scopus 로고
    • Development of neuropathy in patients with myeloma treated with thalidomide: Patterns of occurrence and the role of electrophysiologic monitoring
    • Mileshkin L, Stark R, Day B, et al. Development of neuropathy in patients with myeloma treated with thalidomide: patterns of occurrence and the role of electrophysiologic monitoring. J Clin Oncol. 2006;24:4507-4514.
    • (2006) J Clin Oncol , vol.24 , pp. 4507-4514
    • Mileshkin, L.1    Stark, R.2    Day, B.3
  • 69
    • 3042735765 scopus 로고    scopus 로고
    • Thalidomide for patients with relapsed multiple myeloma after high-dose chemotherapy and stem cell transplantation: Results of an open-label multicenter phase 2 study of efficacy, toxicity and biological activity
    • Richardson P, Schlossman R, Jagannath S, et al. Thalidomide for patients with relapsed multiple myeloma after high-dose chemotherapy and stem cell transplantation: results of an open-label multicenter phase 2 study of efficacy, toxicity and biological activity. Mayo Clin Proc. 2004;79:875-882.
    • (2004) Mayo Clin Proc , vol.79 , pp. 875-882
    • Richardson, P.1    Schlossman, R.2    Jagannath, S.3
  • 70
    • 2942748363 scopus 로고    scopus 로고
    • Thalidomide sensory neurotoxicity: A clinical and neurophysiology study
    • Cavaletti G, Beronio A, Reni L, et al. Thalidomide sensory neurotoxicity: a clinical and neurophysiology study. Neurology. 2004;62:2291.
    • (2004) Neurology , vol.62 , pp. 2291
    • Cavaletti, G.1    Beronio, A.2    Reni, L.3
  • 71
    • 0036446745 scopus 로고    scopus 로고
    • Incidence and risk factors for thalidomide neuropathy: A prospective study of 135 dermatologic patients
    • Bastuji-Garin S, Ochonisky S, Bouche P, et al. Incidence and risk factors for thalidomide neuropathy: a prospective study of 135 dermatologic patients. J Invest Dermatol. 2002;119:1020-1026.
    • (2002) J Invest Dermatol , vol.119 , pp. 1020-1026
    • Bastuji-Garin, S.1    Ochonisky, S.2    Bouche, P.3
  • 72
    • 0034727058 scopus 로고    scopus 로고
    • Life-threatening toxic epidermal necrolysis with thalidomide therapy for myeloma
    • Rajkumar SV, Gertz MA, Witzig TE. Life-threatening toxic epidermal necrolysis with thalidomide therapy for myeloma. N Engl J Med. 2000;343:972-973.
    • (2000) N Engl J Med , vol.343 , pp. 972-973
    • Rajkumar, S.V.1    Gertz, M.A.2    Witzig, T.E.3
  • 73
    • 0037381374 scopus 로고    scopus 로고
    • Dermatologic side effects of thalidomide in patients with multiple myeloma
    • Hall VC, El-Azhary RA, Bouwhuis S, et al. Dermatologic side effects of thalidomide in patients with multiple myeloma. J Am Acad Dermatol. 2003;48:548-552.
    • (2003) J Am Acad Dermatol , vol.48 , pp. 548-552
    • Hall, V.C.1    El-Azhary, R.A.2    Bouwhuis, S.3
  • 74
    • 0036532258 scopus 로고    scopus 로고
    • Hypothyroidism in patients with multiple myeloma following treatment with thalidomide
    • Badros AZ, Siegel E, Bodenner D, et al. Hypothyroidism in patients with multiple myeloma following treatment with thalidomide. Am J Med. 2002; 112:412-413.
    • (2002) Am J Med , vol.112 , pp. 412-413
    • Badros, A.Z.1    Siegel, E.2    Bodenner, D.3
  • 75
    • 0035990828 scopus 로고    scopus 로고
    • Phase II trial of thalidomide in renal cell carcinoma
    • Escudier B, Lassau N, Couanet D, et al. Phase II trial of thalidomide in renal cell carcinoma. Ann Oncol. 2002;13:1029-1035.
    • (2002) Ann Oncol , vol.13 , pp. 1029-1035
    • Escudier, B.1    Lassau, N.2    Couanet, D.3
  • 76
    • 0037350158 scopus 로고    scopus 로고
    • Severe hepatic toxicity due to thalidomide in relapsed multiple myeloma
    • Trojan A, Chasse E, Gay B, et al. Severe hepatic toxicity due to thalidomide in relapsed multiple myeloma. Ann Oncol. 2003;14:501-502.
    • (2003) Ann Oncol , vol.14 , pp. 501-502
    • Trojan, A.1    Chasse, E.2    Gay, B.3
  • 77
    • 0347989302 scopus 로고    scopus 로고
    • Pharma- cokinetics of thalidomide in patients with impaired renal function and while on and off dialysis
    • Eriksson T, Hoglund P, Turesson I, et al. Pharma- cokinetics of thalidomide in patients with impaired renal function and while on and off dialysis. J Pharm Pharmacol. 2003;55:1701-1706.
    • (2003) J Pharm Pharmacol , vol.55 , pp. 1701-1706
    • Eriksson, T.1    Hoglund, P.2    Turesson, I.3
  • 78
    • 3242755855 scopus 로고    scopus 로고
    • Thalidomide alone or in combination with dexamethasone in patients with advanced, relapsed or refractory multiple myeloma and renal failure
    • Tosi P, Zamagni E, Cellini C, et al. Thalidomide alone or in combination with dexamethasone in patients with advanced, relapsed or refractory multiple myeloma and renal failure. Eur J Haematol. 2004;73:98-103.
    • (2004) Eur J Haematol , vol.73 , pp. 98-103
    • Tosi, P.1    Zamagni, E.2    Cellini, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.