The pharmacology of mesolimbic dopamine neurons: A dual-probe microdialysis study in the ventral tegmental area and nucleus accumbens of the rat brain

Journal of Neuroscience

Volumn 16, Issue 8, 1996, Pages 2605-2611

  Westerink, B H C ^a   Kwint, H F ^a   DeVries, J B ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

CGP 52432; dopamine; microdialysis; NMDA; nucleus accumbens; VTA

Indexed keywords

3 AMINO 1 HYDROXY 2 PYRROLIDINONE; 4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ATROPINE; BACLOFEN; BICUCULLINE; DIZOCILPINE; DOPAMINE 2 RECEPTOR; KAINIC ACID; MECAMYLAMINE; MUSCIMOL; N METHYL DEXTRO ASPARTIC ACID; SULPIRIDE; [3 (3,4 DICHLOROBENZYLAMINO)PROPYL](DIETHOXYMETHYL)PHOSPHINIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; LIMBIC SYSTEM; MALE; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM;

EID: 0029961667     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-08-02605.1996     Document Type: Article

References (41)

1. Bayer VE, Pickel VM (1991) GABA-labeled terminals form proportionally more synapses with dopaminergic neurons having low densities of tyrosine hydroxylase immunoreactivity in rat ventral tegmental area. Brain Res 559:44-55.
2. Blackburn JR, Pfaus JG, Phillips AG (1992) Dopamine functions in appetitive and defensive behaviours. Prog Neurobiol 39:247-279.
3. Charlety PJ, Grenhoff J, Chergru K, De la Chapelle B, Buda M, Svensson TH, Chouvet G (1991) Bursts firing of mesencephalic dopaminc neurons is inhibited by somatodendritic application of kynurenate. Acta Physiol Scand 142:105-112.
4. Calabresi P, Lacey MG, North RA (1989) Nicotinic excitation of rat ventral tegmental neurones in vitro studied by intracellular recording. Br J Pharmacol 98:135-140.
5. Cherqui K, Charlety PJ, Akaoka H, Saunier CF, Brunet JL, Buda M, Svensson TH, Chouvet G (1993) Tonic activation of NMDA receptors causes spontaneous burst discharge of rat midbrain dopamine neurons in vivo. Eur J Neurosci 5:137-144.
6. Christie MF, Bridge S, James LB, Beart PM (1989) Excitotoxin lesions suggest an aspartatergic projection from rat medial prefrontal cortex to ventral tegmental area. Acta Physiol Scand 136:135-136.
7. Corrigall WA, Coen KM, Adamson KL (1994) Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area. Brain Res 653:278-284.
8. Fibiger HC, Philips AG (1986) Reward, motivation, cognition: psychobiology of mesotelenccphalic dopamine systems. In: Handbook of physiology, Vol 4, Intrinsic regulatory systems of the brain, pp 647-675. Bethesda: American Physiology Society.
9. French ED, Mura A, Wang T (1993) MK-80L phencyclidine (PCP), and PCP-like drugs increase burst firing in rat A10 dopamine neurons: comparison to competitive NMDA antagonists. Synapse 13:108-116.
10. Gonon FG, Buda MJ (1985) Regulation of dopamine release by impulse flow and by autoreceptors as studied by in vivo voltammetry in the rat striatum. Neuroscience 41:765-774.
11. Grace AA, Bunney BS (1979) Paradoxal GABA excitation of nigral dopaminergic cells: indirect mediation through reticulata inhibitory neurons. Eur J Pharmacol 59:211-218.
12. Jiang ZG, Pessia M, North RA (1993) Dopamine and baclofen inhibit the hyperpolarization-activated cation current in rat ventral tegmental neurones. J Physiol (Lond) 462:753-764.
13. Johnson SW, North RA (1992) Two types of neurone in the rat ventral tegmental area and their synaptic inputs. J Physiol (Lond) 450:455-468.
14. Johnson SW, Seutin V, North RA (1992) Burst firing in dopamine neurons induced by N-methyl-D-aspartate: role of electrogenic sodium pump. Science 258:665-657.
15. Kalivas P (1993) Neurotransmitter regulation of dopamine neurons in the ventral tegmental area. Brain Res Rev 18:75-113.
16. Klitenick MA, DeWitte P, Kalivas PW (1992) Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study. J Neurosci 12:2623-2632.
17. Lacey MG, Calabresi P, North RA (1990) Muscarine depolarizes rat substantia nigra zona compacta and ventral tegmental neurons in vitro through M1-like receptors. J Pharmacol Exp Ther 253:395-400.
18. B autoreceptor antagonist in rat cerebral cortex. Eur J Pharmacol 237:191-195.
19. Le Moal M, Simon H (1991) Mesocorticolimbic dopaminergic network: functional and regulatory roles. Physiol Rev 155-234.
20. Leviel V, Chéramy A, Nieoullon A, Glowinski J (1979) Symmetric bilateral changes in dopamine release from the caudate nuclei of the cat induced by unilateral nigral application of glycine and GABA related compounds. Brain Res 174:259-270.
21. Nastuk MA, Graybiel AM (1991) Pharmacologically defined M1 and M2 muscarinic cholinergic binding sites in the cat's substantia nigra: development and maturity. Brain Res Dev Brain Res 61:1-10.
22. Nieoullon A, Cheramy A, Glowinski J (1977) Release of dopamine in vivo from cat substantia nigra. Nature 266:375-377.
23. Nissel M, Nomikos GG, Svensson TH (1994a) Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area. Synapse 16:36-44.
24. Nissel M, Nomikos GG, Svensson TH (1994b) Infusion of nicotine in the ventral tegmental area of the nucleus accumbens of the rat differently affects accumbal dopamine release. Pharmacol Toxicol 75:348-352.
25. Overton P, Clark D (1992) Iontophoretically administered drugs acting at the N-methyl-D-aspartate receptor modulate burst firing in A9 dopamine neurons in the rat. Synapse 10:131-140.
26. Paxinos G, Watson C (1982) The rat brain in stereotaxic coordinates. New York: Academic.
27. Parker GC, Winn P (1992) Additivity of nicotinic and muscarinic cholinergic stimulation of substantia nigra. NeuroReport 3:1105-1108.
28. Sachs BD, Meisel RL (1988) The physiology of male sexual behavior. In: The physiology of reproduction (Knobil E, Neill J, eds), pp 1393-1485. New York: Raven.
29. Santiago M, Westerink BHC (1991) The regulation of dopamine release from nigrostriatal neurons in conscious rats: the role of somatodendritic autoreceptors. Eur J Pharmacol 204:79-85.
30. Santiago M, Westerink BHC (1992) The role of GABA receptors in the control of nigrostriatal dopaminergic neurons: a microdialysis study in awake rats. Eur J Pharmacol 219:175-181.
31. Seutin V, Verbanck P, Massotte L, Dresse A (1990) Evidence for the presence of N-methyl-D-aspartate receptors in the ventral tegmental area of the rat: an electrophysiological in vitro study. Brain Res 514:147-150.
32. Seutin V, Johnson SW, North RA (1994) Effect of dopamine and baclofen on N-methyl-D-aspartate-induced burst firing in rat ventral tegmental neurons. Neuroscience 58:201-206.
33. Suaud-Chagny MF, Chergui K, Chouvet G, Gonon F (1992) Relationship between dopamine release in the nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area. Neuroscience 49:63-72.
34. A receptor-mediated inhibition of rat substantia nigra dopaminergic neurons by pars reticulata projection neurons. J Neurosci 15:3092-3103.
35. Wang T, French ED (1993) Electrophysiological evidence for the existence of NMDA and non-NMDA receptors on rat ventral tegmental neurons. Synapse 13:270-277.
36. Wang T, O'Connor WT, Ungerstedt U, French ED (1994) N-methyl-D-aspartic acid biphasically regulates the biochemical and electrophysiological response of A10 dopamine neurons in the ventral tegmental area: in vivo microdialysis and in vitro electrophysiological studies. Brain Res 666:255-262.
37. Westerink BHC, Santiago M, deVries JB (1992) The release of dopamine from nerve terminals and dendrites of nigrostriatal neurons induced by excitatory amino acids in the conscious rat. Naunyn Schmiedebergs Arch Pharmacol 345:523-529.
38. Yeomans JS, Mathur A, Tampakeras M (1993) Rewarding brain stimulation: role of tegmental cholinergic neurons that activate dopamine neurons. Behav Neurosci 107:1077-1087.
39. Yoshida M, Yokoo H, Tanaka T, Mizoguchi K, Emoto H, Ishi H, Tanaka M (1993) Facilitatory modulation of mesolimbic dopamine neuronal activity by a mu-opioid agonist and nicotine as examined with in vivo microdialysis. Brain Res 624:277-280.
40. Yoshida M, Yokoo H, Tanaka T, Emoto H, Tanaka M (1994) Opposite changes in the mesolimbic dopamine metabolism in the nerve terminal and cell body sites induced by locally infused baclofen in the rat. Brain Res 636:111-114.
41. Zhang J, Chiodo LA, Freeman AS (1994) Influence of excitatory amino acid receptor subtypes on the electrophysiological activity of dopaminergic and nondopaminergic neurons in rat substantia nigra. J Pharmacol Exp Ther 269:313-321.