A β-carboline-1-one mimic of the anticancer Amaryllidaceae constituent pancratistatin: Synthesis and biological evaluation

Angewandte Chemie - International Edition

Volumn 43, Issue 40, 2004, Pages 5342-5346

  Rinner, Uwe ^a   Hudlicky, Tomas ^a   Gordon, Heather ^a   Pettit, George R ^b  

^a BROCK UNIVERSITY   (Canada)

^b ARIZONA STATE UNIVERSITY   (United States)

Author keywords

Antitumor agents; Asymmetric synthesis; Natural products; Pancratistatin; Synthetic methods

Indexed keywords

CELLS; SYNTHESIS (CHEMICAL); TUMORS;

ENZYMATIC DIHYDROXYLATION; INDOLE DERIVATIVES;

DRUG THERAPY;

7 DEOXYPANCRATISTATIN; BETA CARBOLIN 1 ONE; BETA CARBOLINE DERIVATIVE; HYDROXYL GROUP; LYCORICIDINE; NARCICLASINE; NATURAL PRODUCT; PANCRATISTATIN; PHENANTHRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

AMARYLLIDACEAE; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASYMMETRIC SYNTHESIS; ELECTRICITY; GEOMETRY; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE IMAGING; PHARMACOPHORE; PLANT; RNA TRANSCRIPTION;

AMARYLLIDACEAE ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARBOLINES; HYDROGEN BONDING; ISOQUINOLINES; MOLECULAR MIMICRY; MOLECULAR STRUCTURE; PLANTS, MEDICINAL; STEREOISOMERISM;

EID: 7244260408     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200460218     Document Type: Article

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