Cyclooxygenase-2 expression in experimental post-transplant obliterative bronchiolitis

Journal of Pathology

Volumn 204, Issue 3, 2004, Pages 340-348

  Päiväniemi, Outi E ^a,b   Maasilta, Paula K ^a   Alho, Hanni S ^a   Wolff, C Henrik J ^a   Salminen, Ulla Stina ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b KANTA HÄME CENTRAL HOSPITAL   (Finland)

Author keywords

COX 2; Experimental obliterative bronchiolitis; Lung transplantation

Indexed keywords

AZATHIOPRINE; CYCLOOXYGENASE 2; CYCLOSPORIN A; DICLOFENAC; EOSIN; EVEROLIMUS; HEMATOXYLIN; IMMUNOGLOBULIN G; LINCOMYCIN; METHYLPREDNISOLONE; MONOCLONAL ANTIBODY; RAPAMYCIN;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOGRAFT; BRONCHIOLITIS; CALCULATION; CELL PROLIFERATION; CLINICAL OBSERVATION; CONTROLLED STUDY; FOLLOW UP; GRAFT VERSUS HOST REACTION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROBLAST; LUNG TRANSPLANTATION; NONHUMAN; PATHOGENESIS; POSTOPERATIVE INFECTION; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RATING SCALE; SWINE;

ANIMALS; AZATHIOPRINE; BRONCHI; BRONCHIOLITIS OBLITERANS; CHONDROCYTES; CYCLOOXYGENASE 2; CYCLOSPORINE; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FIBROBLASTS; FIBROSIS; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; ISOENZYMES; MACROPHAGES; METHYLPREDNISOLONE; POSTOPERATIVE PERIOD; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SIROLIMUS; SWINE;

EID: 7244258909     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1631     Document Type: Article

References (31)

1. Trulock EP, Edwards LB, Taylor DO, et al. The registry of the International Society for Heart and Lung Transplantation: Twentieth Official Adult Lung and Heart-Lung Transplant Report 2003. J Heart Lung Transplant 2003; 22: 625-635.
2. Estenne M, Maurer JR, Boehler A, et al. Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria. J Heart Lung Transplant 2002; 21: 297-310.
3. Boehler A, Kesten S, Weder W, et al. Bronchiolitis obliterans after lung transplantation. Chest 1998; 114: 1411-1426.
4. Elssner A, Vogelmeier C. The role of neutrophils in the pathogenesis of obliterative bronchiolitis after lung transplantation. Transplant Infect Dis 2001; 3: 168-176.
5. Mitchell JA, Larkin S, Williams TJ. Cyclooxygenase-2 regulation and relevance in inflammation. Biochem Pharmacol 1995; 10: 1535-1542.
6. Kam PCA, See AU-L. Cyclo-oxygenase isoenzymes: physiological and pharmacological role. Anaesthesia 2000; 55: 442-449.
7. 2 production by IFN-γ in human macrophages. J Immunol 1998; 161: 2441-2448.
8. Redington AE, Meng Q-H, Springall DR, et al. Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in the airway epithelium of asthmatic subjects and regulation by corticosteroid treatment. Thorax 2001; 56: 351-357.
9. Gilroy DW, Colville-Nash PR. New insights into the role of COX-2 in inflammation. J Mol Med 2000; 78: 121-129.
10. Watkins DN, Peroni DJ, Lenzo JC, et al. Expression and localization of COX-2 in human airways and cultured airway epithelial cells. Eur Respir J 1999; 13: 999-1007.
11. Yang X, Ma N, Szabolcs MJ, et al. Upregulation of COX-2 during cardiac allograft rejection. Circulation 2000; 101: 430-438.
12. Salminen US, Maasilta P, Taskinen E, et al. Prevention of small airway obliteration in a swine heterotopic lung allograft model. J Heart Lung Transplant 2000; 19: 193-206.
13. Uusitalo MH, Salminen US, Ikonen TS, et al. Alloimmune injury preceding airway obliteration in porcine heterotopic lung implants: a histologic and immunohistologic study. Transplantation 1999; 68: 970-975.
14. King MB, Pedtke AC, Levrey-Hadden HL, et al. Obliterative airway disease progress in heterotopic airway allograft without persistent alloimmune stimulus. Transplantation 2002; 74 557-562.
15. Adams BF, Brazeton T, Morris RE. The role of respiratory epithelium in a rat model of obliterative airway disease. Transplantation 2000; 69: 661-664.
16. Maasilta PK, Salminen US, Lautenschlager IT, et al. Immune cells and immunosuppression in a porcine bronchial model of obliterative bronchiolitis. Transplantation 2001; 72: 998-1005.
17. Schmedtje JF, Ji YS, Liu WL, et al. Hypoxia induces cyclooxygenase-2 via the NF-κB p65 transcription factor in human vascular endothelial cells. J Biol Chem 1997; 272: 601-608.
18. Wolff H, Saukkonen K, Anttila S, et al. Expression of cyclooxygenase-2 in human lung carcinoma. Cancer Res 1998; 58 4997-5000.
19. Dubois RN. Review article: cyclooxygenase - a target for colon cancer prevention. Aliment Pharmacol Ther 2000; 14: 64-67.
20. Davies G, Martin LA, Sacs N, et al. Cyclooxygenase-2 (COX-2), aromatase and breast cancer: a possible role for COX-2 inhibitors in breast cancer chemoprevention. Ann Oncol 2002; 13 669-678.
21. Xu XC. Cox-2 inhibitors in cancer treatment and prevention, a recent development. Anticancer Drugs 2002; 13: 127-137.
22. Hida T, Yatabe Y, Achiwa H, et al. Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res 1998; 58: 3761-3764.
23. Lassus P, Wolff H, Andersson S. Cyclooxygenase-2 in human perinatal lung. Pediatr Res 2000; 47: 602-605.
24. Bundy RE, Marczin N, Birks EF, et al. Transplant atherosclerosis: role of phenotypic modulation of vascular smooth muscle by nitric oxide. Gen Pharmacol 2000; 34: 73-84.
25. Reichenspurner H, Girgis RE, Robbins RC, et al. Obliterative bronchiolitis after lung and heart-lung transplantation. Ann Thorac Surg 1995; 60: 1845-1853.
26. Baker CSR, Hall RJC, Evans TJ, et al. Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages. Arterioscler Thromb Vasc Biol 1999; 19: 646-655.
27. Salminen US, Maasilta P, Harjula A, et al. Nitric oxide in the development of obliterative bronchiolitis in a heterotopic pig model. Transplantation 2002; 73: 1724-1729.
28. Ma N, Szabolcs MJ, Sun J, et al. The effect of selective inhibition of cyclooxygenase (COX)-2 on acute cardiac allograft rejection. Transplantation 2002; 74: 1534.
29. 1 Shortening and nitric oxide-mediated inhibition of vascular smooth muscle cell proliferation. Circulation 2003; 108: 1015-1021.
30. Goldstein RH, Polgar P. The effect of interaction of bradykinin and prostaglandins on protein and collagen production by lung fibroblasts. J Biol Chem 1982; 257: 8530-8533.
31. Mio T, Nagai S, Kitaichi M, Kawatani A, Izumi T. Proliferative characteristics of fibroblast lines derived from open lung biopsy specimens of patients with IPF (UIP). Chest 1992; 102: 832-837.