Dual functionality of cyclooxygenase-2 as a regulator of tumor necrosis factor-mediated G1 shortening and nitric oxide-mediated inhibition of vascular smooth muscle cell proliferation

Circulation

Volumn 108, Issue 8, 2003, Pages 1015-1021

  Haider, Asifa ^b   Lee, Irene ^b   Grabarek, Jerzy ^b   Darzynkiewicz, Zbigniew ^b   Ferreri, Nicholas R ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b NONE

Author keywords

Muscle, smooth; Nitric oxide; Prostaglandins; Thromboxane

Indexed keywords

ANGIOTENSIN; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTACYCLIN; THROMBOXANE A2; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; HYPERTROPHY; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL CYCLE PROTEINS; CELL DIVISION; CELLS, CULTURED; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DNA; ENZYME INHIBITORS; EPOPROSTENOL; G1 PHASE; ISOENZYMES; MALE; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; THROMBOXANE A2; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEINS;

EID: 0042358724     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000085211.97972.2C     Document Type: Article

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