Role of metallothionein1h in cisplatin resistance of non-small cell lung cancer cells

Chinese Journal of Cancer Research

Volumn 21, Issue 4, 2009, Pages 247-254

  Hou, Xin Fang ^a   Fan, Qing Xia ^b,c   Wang, Liu Xing ^b,c   Lu, Shi Xin ^d  

^a Henan Tumor Hospital   (China)

^b ZHENGZHOU UNIVERSITY   (China)

^c THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^d PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; Drug resistance; Metallothionein; MT1H; Non small cell lung cancer

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CISPLATIN; METALLOTHIONEIN I; METALLOTHIONEIN I H; PLASMID DNA; PROTEIN BAX; PROTEIN BCL 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; DRUG SENSITIVITY; FLOW CYTOMETRY; GENE CONSTRUCT; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LUNG NON SMALL CELL CANCER; NICK END LABELING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 72349087449     PISSN: 10009604     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11670-009-0247-9     Document Type: Article

References (27)

1. A.K. West R. Stallings C.E. Hildebrand, et al. 1990 Human metallothionein genes: structure of the functional locus at 16q13[J] Genomics 8 513 518 10.1016/0888-7543(90)90038-V 1:CAS:528:DyaK3MXit1ams74%3D 2286373
2. M.G. Cherian P.C. Huang C.D. Klaassen, et al. 1993 National Cancer Institute workshop on the possible roles of metallothionein in carcinogenesis[J] Cancer Res 53 922 925 1:STN:280:DyaK3s7ltlOqtQ%3D%3D 8428370
3. M.G. Cherian S.B. Howell N. Imura, et al. 1994 Role of metallothionein in carcinogenesis[J] Toxicol Appl Pharmacol 126 1 5 10.1006/taap.1994.1083 1:CAS:528:DyaK2cXjt1SgtrY%3D 8184419 (Pubitemid 24168861)
4. R. Shimoda W.E. Achanzar W. Qu, et al. 2003 Metallothionein is a potential negative regulator of apoptosis[J] Toxicol Sci 73 294 300 10.1093/toxsci/kfg095 1:CAS:528:DC%2BD3sXktVCgu7s%3D 12700406 (Pubitemid 36701735)
5. M. Yamasaki T. Nomura F. Sato, et al. 2007 Metallothionein is up-regulated under hypoxia and promotes the survival of human prostate cancer cells[J] Oncol Rep 18 1145 1153 1:CAS:528:DC%2BD2sXhtlKhsr7J 17914565
6. B.H. Bay R. Jin J. Huang, et al. 2006 Metallothionein as a prognostic biomarker in breast cancer[J] Exp Biol Med(Maywood) 231 1516 1521 1:CAS:528:DC%2BD28XhtVylt7%2FO
7. R. Jin V.T. Chow P.H. Tan, et al. 2002 Metallothionein 2A expression is associated with cell prolifetation in breast cancer[J] Carcinogenesis 23 81 86 10.1093/carcin/23.1.81 1:CAS:528:DC%2BD38XptFSrsw%3D%3D 11756227
8. J.H. Chun H.K. Kim E. Kim, et al. 2004 Increased expression of metallothionein is associated with irinotecan resistance in gastric cancer[J] Cancer Res 64 4703 4706 10.1158/0008-5472.CAN-04-1063 1:CAS:528: DC%2BD2cXls1Oms7k%3D 15256434 (Pubitemid 38924509)
9. M. Karin R.I. Richards 1982 Human metallothionein genes-primary structure of the metallothionein-II gene and a related processed gene[J] Nature 299 797 802 10.1038/299797a0 1:CAS:528:DyaL3sXktVWitL8%3D 7133118
10. R.I. Richards A. Heguy M. Karin 1984 Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids[J] Cell 37 263 272 10.1016/0092-8674(84)90322-2 1:CAS:528:DyaL2cXkvVCrs70%3D 6327055
11. A. Heguy A. West R.I. Richards, et al. 1986 Structure and tissue-specific expression of the human metallothionein IB gene[J] Mol Cell Biol 6 2149 2157 1:CAS:528:DyaL28XksFGmsLw%3D 3785191
12. C.J. Schmidt M.F. Jubier D.H. Hamer 1985 Structure and expression of two human metallothionein-I isoform genes and a related pseudogene[J] J Biol Chem 260 7731 7737 1:CAS:528:DyaL2MXks1Gqtr8%3D 2581970
13. U. Varshney N. Jahroudi R. Foster, et al. 1986 Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids[J] Mol Cell Biol 6 26 37 1:CAS:528:DyaL28XhtVegtbg%3D 3023827
14. F.A. Stennard A.F. Holloway J. Hamilton, et al. 1994 Characterisation of six additional human metallothionein genes[J] Biochim Biophys Acta 1218 357 365 1:CAS:528:DyaK2cXmslegu7o%3D 8049263
15. R.D. Palmiter S.D. Findley T.E. Whitmore, et al. 1992 MT-III, a brain-specific member of the metallothionein gene family[J] Proc Natl Acad Sci USA 89 6333 6337 10.1073/pnas.89.14.6333 1:CAS:528:DyaK3sXktVegsL0%3D 1631128
16. C.J. Quaife S.D. Findley J.C. Erickson, et al. 1994 Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia[J] Biochemistry 33 7250 7259 10.1021/bi00189a029 1:CAS:528:DyaK2cXktlWksr0%3D 8003488 (Pubitemid 24208763)
17. J.H. Kägi A. Schäffer 1988 Biochemistry of metallothionein [J] Biochemistry 27 8509 8515 10.1021/bi00423a001 3064814 (Pubitemid 18275219)
18. J.E. Bylander S.L. Li M.A. Sens, et al. 1995 Exposure of human proximal tubule cells to cytotoxic levels of CdC12 induces the additional expression of metallothionein 1A mRNA[J] Toxicol Lett 76 209 217 10.1016/0378-4274(95)80005-X 1:CAS:528:DyaK2MXltV2ksLs%3D 7762008
19. H. Xia Q. Mao H.L. Paulson, et al. 2002 siRNA-mediated gene silencing in vitro and in vivo[J] Nat Biotechnol 20 1006 1010 10.1038/nbt739 1:CAS:528:DC%2BD38XnsVGkt74%3D 12244328
20. M.S. Duxbury H. Ito E. Benoit, et al. 2003 RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity[J] Biochem Biophys Res Commun 311 786 792 10.1016/j.bbrc.2003. 10.060 1:CAS:528:DC%2BD3sXos12lu7w%3D 14623342 (Pubitemid 37377726)
21. S. Filleur A. Courtin S. Ait-Si-Ali, et al. 2003 SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth[J] Cancer Res 63 3919 3922 1:CAS:528:DC%2BD3sXlsFOjtbs%3D 12873985
22. D. Wang S.J. Lippard 2005 Cellular processing of platinum anticancer drugs[J] Nat Rev Drug Discov 4 307 320 10.1038/nrd1691 1:CAS:528: DC%2BD2MXivVart7c%3D 15789122 (Pubitemid 41130944)
23. F. Zunino P. Perego S. Pilotti, et al. 1997 Role of apoptotic response in cellular resistance to cytotoxic agents[J] Pharmacol Ther 76 177 185 10.1016/S0163-7258(97)00086-7 1:CAS:528:DyaK1cXlsVKl 9535179 (Pubitemid 28078570)
24. J.C. Reed 1999 Mechanisms of apoptosis avoidance in cancer[J] Curr Opin Oncol 11 68 75 10.1097/00001622-199901000-00014 1:CAS:528:DyaK1MXhvVGns7s%3D 9914881 (Pubitemid 29082059)
25. J.C. Reed 1997 Double identity for proteins of the Bcl-2 family[J] Nature 387 773 776 10.1038/42867 1:CAS:528:DyaK2sXktVOlsr0%3D 9194558 (Pubitemid 27270895)
26. M.A. Estève M. Carré V. Bourgarel-Rey, et al. 2006 Bcl-2 down-regulation and tubulin subtype composition are involved in resistance of ovarian cancer cells to vinflunine[J] Mol Cancer Ther 5 2824 2833 10.1158/1535-7163.MCT-06-0277 17121929 (Pubitemid 44849009)
27. M.E. McCurrach T.M. Connor C.M. Knudson, et al. 1997 Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis[J] Proc Natl Acad Sci USA 94 2345 2349 10.1073/pnas.94.6.2345 1:CAS:528:DyaK2sXhvF2lurk%3D 9122197 (Pubitemid 27136877)