메뉴 건너뛰기




Volumn 75, Issue 1, 2010, Pages 14-19

Free Radical Theory of Aging: Implications in Male Infertility

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; CELL NUCLEUS DNA; COPPER ZINC SUPEROXIDE DISMUTASE; FREE RADICAL; GLUTATHIONE PEROXIDASE; LIPOFUSCIN; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; TELOMERASE; TESTOSTERONE;

EID: 72249114003     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2009.05.025     Document Type: Review
Times cited : (83)

References (50)
  • 1
    • 0035140143 scopus 로고    scopus 로고
    • Effects of male age on semen quality and fertility: a review of the literature
    • Kidd S.A., Eskenazi B., and Wyrobek A.J. Effects of male age on semen quality and fertility: a review of the literature. Fertil Steril 75 (2001) 237-248
    • (2001) Fertil Steril , vol.75 , pp. 237-248
    • Kidd, S.A.1    Eskenazi, B.2    Wyrobek, A.J.3
  • 2
    • 0034253464 scopus 로고    scopus 로고
    • Effects of aging on male fertility?
    • Plas E., Berger P., Hermann M., et al. Effects of aging on male fertility?. Exp Gerontol 35 (2000) 543-551
    • (2000) Exp Gerontol , vol.35 , pp. 543-551
    • Plas, E.1    Berger, P.2    Hermann, M.3
  • 4
    • 1842486896 scopus 로고    scopus 로고
    • Age-induced apoptosis in the male genital tract of the mouse
    • Jara M., Carballada R., and Esponda P. Age-induced apoptosis in the male genital tract of the mouse. Reproduction 127 (2004) 359-366
    • (2004) Reproduction , vol.127 , pp. 359-366
    • Jara, M.1    Carballada, R.2    Esponda, P.3
  • 5
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman K.B., and Ames B.N. The free radical theory of aging matures. Physiol Rev 78 (1998) 547-581
    • (1998) Physiol Rev , vol.78 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 6
    • 0036420517 scopus 로고    scopus 로고
    • How mitochondrial damage affects cell function
    • James A.M., and Murphy M.P. How mitochondrial damage affects cell function. J Biomed Sci 9 (2002) 475-487
    • (2002) J Biomed Sci , vol.9 , pp. 475-487
    • James, A.M.1    Murphy, M.P.2
  • 7
    • 37349018261 scopus 로고    scopus 로고
    • Clinical relevance of oxidative stress in male factor infertility: an update
    • Agarwal A., Makker K., and Sharma R. Clinical relevance of oxidative stress in male factor infertility: an update. Am J Reprod Immunol 59 (2008) 2-11
    • (2008) Am J Reprod Immunol , vol.59 , pp. 2-11
    • Agarwal, A.1    Makker, K.2    Sharma, R.3
  • 8
    • 40649097305 scopus 로고    scopus 로고
    • Age-related increase of reactive oxygen species in neat semen in healthy fertile men
    • Cocuzza M., Athayde K.S., Agarwal A., et al. Age-related increase of reactive oxygen species in neat semen in healthy fertile men. Urology 71 (2008) 490-494
    • (2008) Urology , vol.71 , pp. 490-494
    • Cocuzza, M.1    Athayde, K.S.2    Agarwal, A.3
  • 9
    • 35448962513 scopus 로고    scopus 로고
    • A continuous correlation between oxidative stress and telomere shortening in fibroblasts
    • Richter T., and von Zglinicki T. A continuous correlation between oxidative stress and telomere shortening in fibroblasts. Exp Gerontol 42 (2007) 1039-1042
    • (2007) Exp Gerontol , vol.42 , pp. 1039-1042
    • Richter, T.1    von Zglinicki, T.2
  • 10
    • 0022922763 scopus 로고
    • Ultrastructure of Leydig's cells in human ageing testes
    • Paniagua R., Amat P., Nistal M., et al. Ultrastructure of Leydig's cells in human ageing testes. J Anat 146 (1986) 173-183
    • (1986) J Anat , vol.146 , pp. 173-183
    • Paniagua, R.1    Amat, P.2    Nistal, M.3
  • 11
    • 33746016268 scopus 로고    scopus 로고
    • Mitochondria: more than just a powerhouse
    • McBride H.M., Neuspiel M., and Wasiak S. Mitochondria: more than just a powerhouse. Curr Biol 16 (2006) R551-R560
    • (2006) Curr Biol , vol.16
    • McBride, H.M.1    Neuspiel, M.2    Wasiak, S.3
  • 12
    • 0034306267 scopus 로고    scopus 로고
    • Mitochondria, oxygen free radicals, disease and ageing
    • Raha S., and Robinson B.H. Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem Sci 25 (2000) 502-508
    • (2000) Trends Biochem Sci , vol.25 , pp. 502-508
    • Raha, S.1    Robinson, B.H.2
  • 13
    • 0842328003 scopus 로고    scopus 로고
    • Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes
    • Green K., Brand M.D., and Murphy M.P. Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes 53 suppl 1 (2004) S110-S118
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Green, K.1    Brand, M.D.2    Murphy, M.P.3
  • 14
    • 0039174315 scopus 로고    scopus 로고
    • Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation
    • Vasquez-Vivar J., Kalyanaraman B., and Kennedy M.C. Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation. J Biol Chem 275 (2000) 14064-14069
    • (2000) J Biol Chem , vol.275 , pp. 14064-14069
    • Vasquez-Vivar, J.1    Kalyanaraman, B.2    Kennedy, M.C.3
  • 15
    • 49249112023 scopus 로고    scopus 로고
    • Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa
    • Koppers A.J., De Iuliis G.N., Finnie J.M., et al. Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa. J Clin Endocrinol Metab 93 (2008) 3199-3207
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3199-3207
    • Koppers, A.J.1    De Iuliis, G.N.2    Finnie, J.M.3
  • 16
    • 0037160091 scopus 로고    scopus 로고
    • Topology of superoxide production from different sites in the mitochondrial electron transport chain
    • St-Pierre J., Buckingham J.A., Roebuck S.J., et al. Topology of superoxide production from different sites in the mitochondrial electron transport chain. J Biol Chem 277 (2002) 44784-44790
    • (2002) J Biol Chem , vol.277 , pp. 44784-44790
    • St-Pierre, J.1    Buckingham, J.A.2    Roebuck, S.J.3
  • 17
    • 0034920441 scopus 로고    scopus 로고
    • Mitochondrial theory of aging matures-roles of mtDNA mutation and oxidative stress in human aging
    • Wei Y.H., Ma Y.S., Lee H.C., et al. Mitochondrial theory of aging matures-roles of mtDNA mutation and oxidative stress in human aging. Zhonghua Yi Xue Za Zhi (Taipei) 64 (2001) 259-270
    • (2001) Zhonghua Yi Xue Za Zhi (Taipei) , vol.64 , pp. 259-270
    • Wei, Y.H.1    Ma, Y.S.2    Lee, H.C.3
  • 18
    • 36549024981 scopus 로고    scopus 로고
    • Clinical relevance of oxidative stress and sperm chromatin damage in male infertility: an evidence based analysis
    • Cocuzza M., Sikka S.C., Athayde K.S., et al. Clinical relevance of oxidative stress and sperm chromatin damage in male infertility: an evidence based analysis. Int Braz J Urol 33 (2007) 603-621
    • (2007) Int Braz J Urol , vol.33 , pp. 603-621
    • Cocuzza, M.1    Sikka, S.C.2    Athayde, K.S.3
  • 19
    • 1542329063 scopus 로고    scopus 로고
    • Aging alters the functional expression of enzymatic and non-enzymatic antioxidant defense systems in testicular rat Leydig's cells
    • Cao L., Leers-Sucheta S., and Azhar S. Aging alters the functional expression of enzymatic and non-enzymatic antioxidant defense systems in testicular rat Leydig's cells. J Steroid Biochem Mol Biol 88 (2004) 61-67
    • (2004) J Steroid Biochem Mol Biol , vol.88 , pp. 61-67
    • Cao, L.1    Leers-Sucheta, S.2    Azhar, S.3
  • 20
    • 33947261701 scopus 로고    scopus 로고
    • Spermatozoa have decreased antioxidant enzymatic capacity and increased reactive oxygen species production during aging in the Brown Norway rat
    • Weir C.P., and Robaire B. Spermatozoa have decreased antioxidant enzymatic capacity and increased reactive oxygen species production during aging in the Brown Norway rat. J Androl 28 (2007) 229-240
    • (2007) J Androl , vol.28 , pp. 229-240
    • Weir, C.P.1    Robaire, B.2
  • 21
    • 33644534186 scopus 로고    scopus 로고
    • Aging and the brown Norway rat leydig cell antioxidant defense system
    • Luo L., Chen H., Trush M.A., et al. Aging and the brown Norway rat leydig cell antioxidant defense system. J Androl 27 (2006) 240-247
    • (2006) J Androl , vol.27 , pp. 240-247
    • Luo, L.1    Chen, H.2    Trush, M.A.3
  • 22
    • 0036023469 scopus 로고    scopus 로고
    • Telomeres in mammalian male germline cells
    • Zalenskaya I.A., and Zalensky A.O. Telomeres in mammalian male germline cells. Int Rev Cytol 218 (2002) 37-67
    • (2002) Int Rev Cytol , vol.218 , pp. 37-67
    • Zalenskaya, I.A.1    Zalensky, A.O.2
  • 24
    • 0031860668 scopus 로고    scopus 로고
    • Telomerase activity in the testis of infertile patients with selected causes
    • Fujisawa M., Tanaka H., Tatsumi N., et al. Telomerase activity in the testis of infertile patients with selected causes. Hum Reprod 13 (1998) 1476-1479
    • (1998) Hum Reprod , vol.13 , pp. 1476-1479
    • Fujisawa, M.1    Tanaka, H.2    Tatsumi, N.3
  • 25
    • 0031717779 scopus 로고    scopus 로고
    • Expression of the RNA component of telomerase during human development and differentiation
    • Yashima K., Maitra A., Rogers B.B., et al. Expression of the RNA component of telomerase during human development and differentiation. Cell Growth Differ 9 (1998) 805-813
    • (1998) Cell Growth Differ , vol.9 , pp. 805-813
    • Yashima, K.1    Maitra, A.2    Rogers, B.B.3
  • 26
    • 0037470062 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening
    • Serra V., von Zglinicki T., Lorenz M., et al. Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening. J Biol Chem 278 (2003) 6824-6830
    • (2003) J Biol Chem , vol.278 , pp. 6824-6830
    • Serra, V.1    von Zglinicki, T.2    Lorenz, M.3
  • 27
    • 0032493742 scopus 로고    scopus 로고
    • Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress
    • Furumoto K., Inoue E., Nagao N., et al. Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress. Life Sci 63 (1998) 935-948
    • (1998) Life Sci , vol.63 , pp. 935-948
    • Furumoto, K.1    Inoue, E.2    Nagao, N.3
  • 28
  • 29
    • 1842611977 scopus 로고    scopus 로고
    • Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells
    • Haendeler J., Hoffmann J., Diehl J.F., et al. Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells. Circ Res 94 (2004) 768-775
    • (2004) Circ Res , vol.94 , pp. 768-775
    • Haendeler, J.1    Hoffmann, J.2    Diehl, J.F.3
  • 30
    • 0034086553 scopus 로고    scopus 로고
    • The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosis
    • Zhu H., Fu W., and Mattson M.P. The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosis. J Neurochem 75 (2000) 117-124
    • (2000) J Neurochem , vol.75 , pp. 117-124
    • Zhu, H.1    Fu, W.2    Mattson, M.P.3
  • 31
    • 33749656530 scopus 로고    scopus 로고
    • The lysosomal-mitochondrial axis theory of postmitotic aging and cell death
    • Terman A., Gustafsson B., and Brunk U.T. The lysosomal-mitochondrial axis theory of postmitotic aging and cell death. Chem Biol Interact 163 (2006) 29-37
    • (2006) Chem Biol Interact , vol.163 , pp. 29-37
    • Terman, A.1    Gustafsson, B.2    Brunk, U.T.3
  • 32
    • 0033796721 scopus 로고    scopus 로고
    • Regulation of Leydig cell steroidogenic function during aging
    • Zirkin B.R., and Chen H. Regulation of Leydig cell steroidogenic function during aging. Biol Reprod 63 (2000) 977-981
    • (2000) Biol Reprod , vol.63 , pp. 977-981
    • Zirkin, B.R.1    Chen, H.2
  • 34
    • 0034881033 scopus 로고    scopus 로고
    • Oxidative stress and protein aggregation during biological aging
    • Squier T.C. Oxidative stress and protein aggregation during biological aging. Exp Gerontol 36 (2001) 1539-1550
    • (2001) Exp Gerontol , vol.36 , pp. 1539-1550
    • Squier, T.C.1
  • 35
    • 0024496063 scopus 로고
    • Age-related deposition of amyloid P component in normal human testis
    • Herriot R., and Walker F. Age-related deposition of amyloid P component in normal human testis. J Pathol 157 (1989) 11-14
    • (1989) J Pathol , vol.157 , pp. 11-14
    • Herriot, R.1    Walker, F.2
  • 36
    • 0025770042 scopus 로고
    • Age-related accumulation of congophilic fibrillar inclusions in endocrine cells
    • Bohl J., Steinmetz H., and Storkel S. Age-related accumulation of congophilic fibrillar inclusions in endocrine cells. Virchows Arch A Pathol Anat Histopathol 419 (1991) 51-58
    • (1991) Virchows Arch A Pathol Anat Histopathol , vol.419 , pp. 51-58
    • Bohl, J.1    Steinmetz, H.2    Storkel, S.3
  • 37
    • 33744745014 scopus 로고    scopus 로고
    • Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis
    • Santos J.H., Meyer J.N., and Van Houten B. Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis. Hum Mol Genet 15 (2006) 1757-1768
    • (2006) Hum Mol Genet , vol.15 , pp. 1757-1768
    • Santos, J.H.1    Meyer, J.N.2    Van Houten, B.3
  • 38
    • 0028979570 scopus 로고
    • Ageing of the hypothalamo-pituitary-testicular axis in men
    • Vermeulen A., and Kaufman J.M. Ageing of the hypothalamo-pituitary-testicular axis in men. Horm Res 43 (1995) 25-28
    • (1995) Horm Res , vol.43 , pp. 25-28
    • Vermeulen, A.1    Kaufman, J.M.2
  • 39
    • 23844530668 scopus 로고    scopus 로고
    • Late-onset hypogonadism in the aging male (LOH): definition, diagnostic and clinical aspects
    • Schubert M., and Jockenhovel F. Late-onset hypogonadism in the aging male (LOH): definition, diagnostic and clinical aspects. J Endocrinol Invest 28 (2005) 23-27
    • (2005) J Endocrinol Invest , vol.28 , pp. 23-27
    • Schubert, M.1    Jockenhovel, F.2
  • 40
    • 0036228939 scopus 로고    scopus 로고
    • Comparison of semen quality in older and younger men attending an andrology clinic
    • Jung A., Schuppe H.C., and Schill W.B. Comparison of semen quality in older and younger men attending an andrology clinic. Andrologia 34 (2002) 116-122
    • (2002) Andrologia , vol.34 , pp. 116-122
    • Jung, A.1    Schuppe, H.C.2    Schill, W.B.3
  • 41
    • 34147108651 scopus 로고    scopus 로고
    • Relationship between age and semen parameters in men with normal sperm concentration: analysis of 6022 semen samples
    • Levitas E., Lunenfeld E., Weisz N., et al. Relationship between age and semen parameters in men with normal sperm concentration: analysis of 6022 semen samples. Andrologia 39 (2007) 45-50
    • (2007) Andrologia , vol.39 , pp. 45-50
    • Levitas, E.1    Lunenfeld, E.2    Weisz, N.3
  • 42
    • 33749995549 scopus 로고    scopus 로고
    • Quantitative effects of male age on sperm motion
    • Sloter E., Schmid T.E., Marchetti F., et al. Quantitative effects of male age on sperm motion. Hum Reprod 21 (2006) 2868-2875
    • (2006) Hum Reprod , vol.21 , pp. 2868-2875
    • Sloter, E.1    Schmid, T.E.2    Marchetti, F.3
  • 43
    • 0346849777 scopus 로고    scopus 로고
    • Effects of age on DNA double-strand breaks and apoptosis in human sperm
    • Singh N.P., Muller C.H., and Berger R.E. Effects of age on DNA double-strand breaks and apoptosis in human sperm. Fertil Steril 80 (2003) 1420-1430
    • (2003) Fertil Steril , vol.80 , pp. 1420-1430
    • Singh, N.P.1    Muller, C.H.2    Berger, R.E.3
  • 44
    • 33745476745 scopus 로고    scopus 로고
    • Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm
    • Wyrobek A.J., Eskenazi B., Young S., et al. Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm. Proc Natl Acad Sci USA 103 (2006) 9601-9606
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 9601-9606
    • Wyrobek, A.J.1    Eskenazi, B.2    Young, S.3
  • 45
    • 46649109138 scopus 로고    scopus 로고
    • Evaluation of nuclear DNA damage in human spermatozoa in men opting for assisted reproduction
    • Shamsi M.B., Kumar R., and Dada R. Evaluation of nuclear DNA damage in human spermatozoa in men opting for assisted reproduction. Indian J Med Res 127 (2008) 115-123
    • (2008) Indian J Med Res , vol.127 , pp. 115-123
    • Shamsi, M.B.1    Kumar, R.2    Dada, R.3
  • 46
    • 33845660012 scopus 로고    scopus 로고
    • The effects of male age on sperm DNA damage in healthy non-smokers
    • Schmid T.E., Eskenazi B., Baumgartner A., et al. The effects of male age on sperm DNA damage in healthy non-smokers. Hum Reprod 22 (2007) 180-187
    • (2007) Hum Reprod , vol.22 , pp. 180-187
    • Schmid, T.E.1    Eskenazi, B.2    Baumgartner, A.3
  • 47
    • 27644443950 scopus 로고    scopus 로고
    • Apoptosis in human unfertilized oocytes after intracytoplasmic sperm injection
    • Bosco L., Ruvolo G., Morici G., et al. Apoptosis in human unfertilized oocytes after intracytoplasmic sperm injection. Fertil Steril 84 (2005) 1417-1423
    • (2005) Fertil Steril , vol.84 , pp. 1417-1423
    • Bosco, L.1    Ruvolo, G.2    Morici, G.3
  • 49
    • 0019846358 scopus 로고
    • Paternal age and Down's syndrome: data from prenatal diagnoses (DFG)
    • Stene J., Stene E., Stengel-Rutkowski S., et al. Paternal age and Down's syndrome: data from prenatal diagnoses (DFG). Hum Genet 59 (1981) 119-124
    • (1981) Hum Genet , vol.59 , pp. 119-124
    • Stene, J.1    Stene, E.2    Stengel-Rutkowski, S.3
  • 50
    • 40349093037 scopus 로고    scopus 로고
    • Epigenetics and assisted reproductive technologies: human imprinting syndromes
    • Lawrence L.T., and Moley K.H. Epigenetics and assisted reproductive technologies: human imprinting syndromes. Semin Reprod Med 26 (2008) 143-152
    • (2008) Semin Reprod Med , vol.26 , pp. 143-152
    • Lawrence, L.T.1    Moley, K.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.