Opioid peptide receptor studies. 14. Stereochemistry determines agonist efficacy and intrinsic efficacy in the [35S]GTP-γ-S functional binding assay

Synapse

Volumn 39, Issue 1, 2001, Pages 64-69

  Dawson, Niamh M ^a   Hamid, Emad H ^b   Egan, Michael F ^b   Meredith, Gloria E ^c  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

Author keywords

Analgesics; Intrinsic efficacy; Opioid receptors

Indexed keywords

ANALGESIC AGENT; MORPHAN DERIVATIVE; NIH 8508; NIH 8509; OPIATE PEPTIDE; OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ISOMER; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY;

ANALGESICS, OPIOID; ANIMALS; BINDING SITES; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MICE; MOLECULAR CONFORMATION; MORPHINANS; RADIOLIGAND ASSAY; RECEPTORS, OPIOID, MU; SULFUR RADIOISOTOPES; TUMOR CELLS, CULTURED;

EID: 0035217224     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2396(20010101)39:1<64::AID-SYN9>3.0.CO;2-J     Document Type: Article

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