The effect of tapering period on plasma pro-inflammatory cytokine levels and performance in elite male cyclists

Journal of Sports Science and Medicine

Volumn 8, Issue 4, 2009, Pages 600-606

  Farhangimaleki, Negin ^a   Zehsaz, Farzad ^a   Tiidus, Peter M ^b  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b WILFRID LAURIER UNIVERSITY   (Canada)

Author keywords

Endurance training; Immune; Interleukin 1 ; Interleukin 6; Performance; Tumor necrosis factor

Indexed keywords

EID: 72249098952     PISSN: None     EISSN: 13032968     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Arnold, M.C., Papanicolaou, D.A., O'Grady, J.A., Lotsikas, A., Dale, J.K., Straus, S.E. and Grafman, J. (2002) Using an interleukin-6 challenge to evaluate neuropsychological performance in chronic fatigue syndrome. Psychological Medicine 32, 1075-1089.
2. Brenner, I.K.M., Natale, V.M. and Vasiliou, P. (1999) Impact of three different types of exercise on components of the inflammatory response. European Journal of Applied Physiology 80, 452-460.
3. Bruunsgaard, H., Skinhoj, P., Qvist, J. and Pedersen, B. K. (1999) Elderly humans show prolonged in vivo inflammatory activity during pneumococcal infections. Journal of Infectious Diseases 180, 551-554.
4. Camus, G., Poortmans, J., Nys, M.I., Deby-Dupont, G., Duchateau, J., Deby, C. and Lamy, M. (1997) Mild endotoxemia and the inflammatory response induced by a marathon race. Clinical Science 92, 415-422.
5. Gleeson, M., Nieman, D.C. and Pedersen, B.K. (2004) Exercise, nutrition and immune function. Journal of Sports Sciences 22, 115-125.
6. Goldshy, R.A., Kindt, T.J. and Osborne, B.A. (2003) Immunology. NewYork: Freeman. 1-8.
7. Houmard, J. (1991) Impact of reduced training on performance in endurance athletes. Sports Medicine 12, 380-393.
8. Houmard, J.A., Scott, B.K. and Justice, C.L. (1994) The effects of taper on performance in distance runners. Medicine and Science in Sports and Exercise 26, 624-631.
9. Kuipers, H., Verstappen, F.T.J. and Keizer, H.A. (1985) Variability of aerobic performance in the laboratory and its physiologic correlates. Sports Medicine 6, 197-201.
10. Metz, J. (2003) Upper respiratory tract infections: who plays, who sits? Current Sports Medicine Reports 2(84), 84-90.
11. Meyer, T., Faude, O., Urhausen, A., Scharhag, J. and Kindermann, W. (2004) Different effects of two regeneration regimens on immunological parameters in cyclists. Medicine and Sciences in Sports and Exercise 36(10), 1743-1749.
12. Mujika, I., Goya, A., Ruiz, E., Grijalba, A., Santisteban, J. and Padilla, S. (2002) Physiological and performance responses to a 6-day taper in middle-distance runners: influence of training frequency. International Journal of Sports Medicine 23, 367-373.
13. Neary, J.P., Martin, T.P. and Reid, D.C. (1992) The effects of a reduced exercise duration taper programme on performance and muscle enzymes of endurance cyclists. European Journal of Applied Physiology 65, 30-36.
14. Neary, J.P., Bhambhani, Y.N. and McKenzie, D.C. (2003a) Effects of different stepwise reduction taper protocols on cycling performance. Canadian Journal of Applied Physiology 28(4), 576-587.
15. Nijs, J., Meeus, M. and Mc Gegor, N.R. (2005) Chronic fatigue syndrome: exercise performance related to immune dysfunction. Medicine and Science in Sports and Exercise 37(10), 1647-1654.
16. Nishimoto, N., Sasai, M., Shima, Y., Nakagawa, M., Matsumoto, T., Shirai, T., Kishimoto, T. and Yoshizaki, K. (2000) Improvement in Castleman's disease by humanized anti-interleukin-6 recep tor antibody therapy. Blood 95, 56-61.
17. Ostrowski, K., Rohde, T., Asp, S., Schjeriing, P. and Pedersen, B.K. (1999) Proand anti-inflammatory cytokine balance in strenuous exercise in humans. Journal of Physiology 515, 287-291.
18. Ostrowski, K., Rohde, T., Zacho, M., Asp, S. and Pedersen, B.K. (1998) Evidence that interieukin-6 is produced in human skeletal muscle during prolonged running. Journal of Physiology 508, 949-953.
19. Peake, J.M., Suzuki, K., Wilson, G., Hordern, M., Yamaya, K., Nosaka, K., Mackinnon, L. and Coombes, J.S. (2005) Exercise-induced muscle damage, plasma cytokines and markers of neutrophil activation. Medicine and Science in Sports and Exercise 37, 737-745.
20. Peake, J.M., Wilson, G., Hordern, M., Suzuki, K., Nosaka, K., Yamaya, K., Mackinnon, L. and Coombes, J. (2004) Changes in neutrophil receptor expression, degranulation and respiratory burst activity after moderate and high intensity exercise. Journal of Applied Physiology 97, 612-618.
21. Pedersen, B.K. and Febbraio, M. (2008) Muscle as an endocrine organ: Focus on muscle-derived interleukin-6. Physiological Review 88, 1379-1406.
22. Pedersen, B.K. and Hoffman-Goetz, L. (2000) Exercise and the immune system: regulation, integration and adaptation. Physiological Review 80, 1055-1081.
23. Plomgard, P., Bouzakri, K., Krogh-Madsen, R., Mittendorf, B., Zierath, J.R. and Pedersen, B.K. (2005) Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. Diabetes 54, 2939-2945.
24. Rietjens, G.J.W.M., Keizer, H.A., Kuipers, H. and Saris, W.H.M. (2001) A reduction in training volume and intensity for 21 days does not impair performance in cyclists. British Journal of Sports Medicine 35, 431-434.
25. Rokitzki, L., Logemann, E. and Keul, J. (1994) Interleukin-6, tumor necrosis factor-alpha and malondialdehyde serum concentration during a marathon-run. International Journal of Sports Medicine 15, 360.
26. Ronsen, O., Kjeldsen-Kragh, J. and Haug, E. (2002) Recovery time affects immunoendocrine responses to a second bout of endurance exercise. American Journal of Physiology Cell Physiology 283, C1612-C1620.
27. Scharhag, J., Meyer, T., Gabriel, H.H.W., Schlick, B., Faude, O. and Kindermann, W. (2006) Does prolonged cycling of moderate intensity affect immune cell function? British Journal of Sports Medicine 39, 171-177.
28. Shepley, B., MacDougall, J.D., Cipriano, N., Sutton, J.R., Tarnopolsky, M.A. and Coates, G. (1992) Physiological effects of tapering in highly trained athletes. Journal of Applied Physiology 72(2), 706-711.
29. Smith, L.L. (2000) Cytokine hypothesis of overtraining: a physiological adaptation to excessive stress? Medicine and Science in Sports and Exercise 32, 317-331.
30. Tuan, TC, Hsu, T.G., Fong, M.C., Hsu, C.F., Tsai, K.K., Lee, C.Y. and Kong, C.W. (2008) Deleterious effects of short-term highintensity exercise on the immune function: evidence from leukocyte mitochondrial alternations and apoptosis. British Journal of Sports Medicine 42(1), 11-15.
31. Tessetore, A., Meeusen, R., Tiberi, M., Cortis, C., Pagano, R. and Capranica, L. (2005) Aerobic and anaerobic profiles, heart rate and match analysis in older soccer players. Ergonomics 48(11-14), 122-129.