Measurement of salivary cortisol with liquid chromatography-tandem mass spectrometry in patients undergoing dynamic endocrine testing

Clinical Endocrinology

Volumn 72, Issue 1, 2010, Pages 17-21

  Perogamvros, Ilias ^a   Owen, Laura J ^b   Keevil, Brian G ^b   Brabant, Georg ^a   Trainer, Peter J ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; TETRACOSACTIDE;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ASSESSMENT; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; HYPOTHALAMUS HYPOPHYSIS SYSTEM; INSULIN TOLERANCE TEST; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; SALIVA; SALIVA ANALYSIS; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; ADRENAL INSUFFICIENCY; ADULT; AGED; AGED, 80 AND OVER; CHROMATOGRAPHY, LIQUID; DIAGNOSTIC TECHNIQUES, ENDOCRINE; FEMALE; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; SALIVA; TANDEM MASS SPECTROMETRY; TIME FACTORS; YOUNG ADULT;

EID: 72249091877     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2009.03582.x     Document Type: Article

References (23)

1. Vining, R.F., McGinley, R.A., Maksvytis, J.J. et al. (1983) Salivary cortisol: a better measure of adrenal cortical function than serum cortisol. Annals of Clinical Biochemistry, 20, 329 335.
2. Nieman, L.K., Biller, B.M., Findling, J.W. et al. (2008) The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline. Journal of Clinical Endocrinology and Metabolism, 93, 1526 1540.
3. Papanicolaou, D.A., Mullen, N., Kyrou, I. et al. (2002) Nighttime salivary cortisol: a useful test for the diagnosis of Cushing's syndrome. Journal of Clinical Endocrinology and Metabolism, 87, 4515 4521.
4. Raff, H., Raff, J.L. Findling, J.W. (1998) Late-night salivary cortisol as a screening test for Cushing's syndrome. Journal of Clinical Endocrinology and Metabolism, 83, 2681 2686.
5. Vining, R.F., McGinley, R.A. Symons, R.G. (1983) Hormones in saliva: mode of entry and consequent implications for clinical interpretation. Clinical Chemistry, 29, 1752 1756.
6. Cohen, J., Ward, G., Prins, J. et al. (2006) Variability of cortisol assays can confound the diagnosis of adrenal insufficiency in the critically ill population. Intensive Care Medicine, 32, 1901 1905.
7. Raff, H., Homar, P.J. Burns, E.A. (2002) Comparison of two methods for measuring salivary cortisol. Clinical Chemistry, 48, 207 208.
8. Jonsson, B.A., Malmberg, B., Amilon, A. et al. (2003) Determination of cortisol in human saliva using liquid chromatography-electrospray tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 784, 63 68.
9. Baid, S.K., Sinaii, N., Wade, M. et al. (2007) Radioimmunoassay and tandem mass spectrometry measurement of bedtime salivary cortisol levels: a comparison of assays to establish hypercortisolism. Journal of Clinical Endocrinology and Metabolism, 92, 3102 3107.
10. Owen, L.J., Wear, J.E. Keevil, B.G. (2007) A simple on-line solid phase extraction liquid chromatography tandem mass spectrometry method for the measurement of salivary cortisol. Clinical Chemistry and Laboratory Medicine, 45, Abstract M341.
11. Viardot, A., Huber, P., Puder, J.J. et al. (2005) Reproducibility of nighttime salivary cortisol and its use in the diagnosis of hypercortisolism compared with urinary free cortisol and overnight dexamethasone suppression test. Journal of Clinical Endocrinology and Metabolism, 90, 5730 5736.
12. Marik, P.E., Pastores, S.M., Annane, D. et al. (2008) Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine. Critical Care Medicine, 36, 1937 1949.
13. Smith, R.E., Maguire, J.A., Stein-Oakley, A.N. et al. (1996) Localization of 11 beta-hydroxysteroid dehydrogenase type II in human epithelial tissues. Journal of Clinical Endocrinology and Metabolism, 81, 3244 3248.
14. Van Uum, S.H., Walker, B.R., Hermus, A.R. et al. (2002) Effect of glycyrrhetinic acid on 11 beta-hydroxysteroid dehydrogenase activity in normotensive and hypertensive subjects. Clinical Science (London), 102, 203 211.
15. Siemens Healthcare Diagnostics Inc 2008) Advia Centaur Immunoassay Systems Customer Bulletin. Siemens Healthcare Diagnostics Ltd, Surrey, UK.
16. Gozansky, W.S., Lynn, J.S., Laudenslager, M.L. et al. (2005) Salivary cortisol determined by enzyme immunoassay is preferable to serum total cortisol for assessment of dynamic hypothalamic-pituitary-adrenal axis activity. Clinical Endocrinology (Oxford), 63, 336 341.
17. Aardal-Eriksson, E., Karlberg, B.E. Holm, A.C. (1998) Salivary cortisol - an alternative to serum cortisol determinations in dynamic function tests. Clinical Chemistry and Laboratory Medicine, 36, 215 222.
18. Arafah, B.M., Nishiyama, F.J., Tlaygeh, H. et al. (2007) Measurement of salivary cortisol concentration in the assessment of adrenal function in critically ill subjects: a surrogate marker of the circulating free cortisol. Journal of Clinical Endocrinology and Metabolism, 92, 2965 2971.
19. Vogeser, M., Briegel, J. Zachoval, R. (2002) Dialyzable free cortisol after stimulation with Synacthen. Clinical Biochemistry, 35, 539 543.
20. Tunn, S., Mollmann, H., Barth, J. et al. (1992) Simultaneous measurement of cortisol in serum and saliva after different forms of cortisol administration. Clinical Chemistry, 38, 1491 1494.
21. Qureshi, A.C., Bahri, A., Breen, L.A. et al. (2007) The influence of the route of oestrogen administration on serum levels of cortisol-binding globulin and total cortisol. Clinical Endocrinology (Oxford), 66, 632 635.
22. O'Beirne, J., Holmes, M., Agarwal, B. et al. (2007) Adrenal insufficiency in liver disease - what is the evidence? Journal of Hepatology, 47, 418 423.
23. Arafah, B.M. (2006) Hypothalamic pituitary adrenal function during critical illness: limitations of current assessment methods. Journal of Clinical Endocrinology and Metabolism, 91, 3725 3745.