Localization of 11β-hydroxysteroid dehydrogenase type II in human epithelial tissues

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 9, 1996, Pages 3244-3248

  Smith, Robin E ^a   Maguire, Julie A ^a   Stein Oakley, Alicia N ^a   Sasano, Hironobu ^b   Takahashi, Ken Ichi ^b   Fukushima, Kouhei ^b   Krozowski, Zygmunt S ^a  

^a ALFRED HOSPITAL   (Australia)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ALDOSTERONE; GLUCOCORTICOID RECEPTOR; MINERALOCORTICOID RECEPTOR; POLYCLONAL ANTIBODY;

ADOLESCENT; ADULT; AGED; ANTIBODY PRODUCTION; ARTICLE; ENZYME LOCALIZATION; ENZYME SPECIFICITY; FEMALE; HAIR FOLLICLE; HUMAN; HUMAN TISSUE; HYPERTENSION; INTESTINE EPITHELIUM; MALE; PAROTID GLAND; PRIORITY JOURNAL; SEBACEOUS GLAND; SUBMANDIBULAR GLAND; SWEAT GLAND;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ADULT; ARTERIOLES; ECCRINE GLANDS; EPIDERMIS; EPITHELIUM; FEMALE; HUMANS; HYDROXYSTEROID DEHYDROGENASES; ILEUM; IMMUNOENZYME TECHNIQUES; MALE; PAROTID GLAND; SALIVARY GLANDS; SKIN; SUBMANDIBULAR GLAND; TISSUE DISTRIBUTION;

EID: 0029847770     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.9.3244     Document Type: Article

References (24)

1. Krozowski ZS, Funder JW. 1983 Renal mineralocorticoid receptors and hippocampal corticosterone-binding species have identical intrinsic steroid specificity. Proc Natl Acad Sci USA. 80:6036-6060.
2. Edwards CR, Stewart PM, Burl D, et al. 1988 Localisation of 11 beta-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet. 2:986-989.
3. Funder JW, Pearce PT, Smith R, Smith AI. 1988 Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science. 242:583-585.
4. Ulick S, Levine LS, Gunczler P, et al. 1979 A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol. J Clin Endocrinol Metab. 49:757-764.
5. Wilson RC, Krozowski ZS, Li K, et al. 1995 A mutation in the HSD11B2 gene in a family with apparent mineralocorticoid excess. J Clin Endocrinol Metab. 80:2263-2266.
6. Mune T, Rogerson FM, Nikkila H, Agarwal AK, White PC. 1995 Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase. Nat Genet. 10:394-399.
7. Stewart PM, Krozowski ZS, Gupta A, et al. 1996 Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11 beta-hydroxysteroid dehydrogenase type 2 gene. Lancet. 347:88-91.
8. Krozowski Z, Maguire JA, Stein-Oakley AN, Dowling J, Smith RE, Andrews RK. 1995 Immunohistochemical localization of the 11 beta-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta. J Clin Endocrinol Metab. 80:2203-2209.
9. Krozowski Z, Wendell K, Ahima R, Harlan R. 1992 Type-I corticosteroid receptor-like immunoreactivity in the rat salivary glands and distal colon - modulation by corticosteroids. Mol Cell Endocrinol. 85:21-32.
10. Kenouch S, Lombes M, Delahaye F, Eugene E, Bonvalet JP, Farman N. 1994 Human skin as target for aldosterone: coexpression of mineralocorticoid receptors and 11 beta-hydroxysteroid dehydrogenase. J Clin Endocrinol Metab. 79:1334-1341.
11. Schulman G, Miller-Diener A, Litwack G, Basil CP. 1986 Characterization of the rat colonic aldosterone receptor and its activation process. J Biol Chem. 261:12102-12106.
12. Rusvai E, Naray-Fejes-Toth A. 1993 A new isoform of 11-beta-hydroxysteroid dehydrogenase in aldosterone target cells. J Biol Chem. 268:10717-10720.
13. Albiston AL, Obeyesekere VR, Smith RE, Krozowski ZS. 1994 Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol. 105:R11-R17.
14. Kyossev Z, Walker PD, Reeves WB. 1996 Immunolocalization of NAD-dependent 11 beta-hydroxysteroid dehydrogenase in human kidney and colon. Kidney Int. 49:271-281.
15. Reid AF, Coghlan JP, Spence CD, Whitworth JA, Scoggins BA. 1989 Studies on spirolactone steroid antagonists in ACTH-induced hypertension in sheep. J Steroid Biochem Mol Biol. 33:1213-1221.
16. Lotti LV, Hand AR. 1988 Endocytosis of parotid salivary proteins by striated duct cells in streptozotocin-diabetic rats. Anat Rec. 221:802-811.
17. Schmid G, Heidland A. 1984 Cation excretion and kallikrein secretion by the rat parotid gland in various hypertensive models. J Cardiovasc Pharmacol. 6:S101-S106.
18. Fuller PJ, Verity K. 1990 Mineralocorticoid receptor gene expression in the gastrointestinal tract: distribution and ontogeny. J Steroid Biochem Mol Biol. 36:263-267.
19. Suzuki S, Ren LJ, Chen H. 1989 Further studies on the effect of aldosterone on Mg2+-HCO3(-)-ATPase and carbonic anhydrase from rat intestinal mucosa. J Steroid Biochem Mol Biol. 33:89-99.
20. Armanini D, Endres S, Kuhnle U, Weber PC. 1988 Parallel determination of mineralocorticoid and glucocorticoid receptors in T- and B-lymphocytes of human spleen. Acta Endocrinol (Copenh). 118:479-482.
21. Fuller PJ, Verity K. 1990 Colonie sodium-potassium adenosine triphosphate subunit gene expression: ontogeny and regulation by adrenocortical steroids. Endocrinology. 127:32-38.
22. Whorwood CB, Ricketts ML, Stewart PM. 1994 Epithelial cell localization of type 211 beta-hydroxysteroid dehydrogenase in rat and human colon endocrinology. 135:2533-2541.
23. Burton AF, Anderson FH. 1983 Inactivation of corticosteroids in intestinal mucosa by 11 beta-hydroxysteroid: NADP oxidoreductase (EC 1.1.1.146). Am J Gastroenterol. 78:627-631.
24. Epple HJ, Schulzke JD, Schmitz H, Fromm M. 1995 Enzyme- and mineralocorticoid receptor-controlled electrogenic na+ absorption in human rectum in vitro. Am J Physiol Gastrointest L. 32:G42-G48.