SAR of N-phenyl piperidine based oral integrin α5β1 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 1, 2010, Pages 65-68

  Zischinsky, Gunther ^a   Osterkamp, Frank ^a   Vossmeyer, Doerte ^a   Zahn, Grit ^a   Scharn, Dirk ^a   Zwintscher, Ariane ^a   Stragies, Roland ^a  

^a Jerini AG   (Germany)

Author keywords

Antagonists; Integrin 5 1; N Phenyl piperidine; Pharmacokinetic profile; Stereoisomers

Indexed keywords

HETEROCYCLIC COMPOUND; INTEGRIN ALPHA 5 BETA 1 ANTAGONIST; N PHENYL PIPERIDINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; IMMUNOREACTIVITY; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; AMINOPYRIDINES; ANIMALS; DOGS; DRUG DESIGN; INTEGRIN ALPHA5BETA1; MALE; PHENYLALANINE; PIPERIDINES; RATS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 72049118818     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.11.030     Document Type: Article

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