Cell-Based Therapies for Musculoskeletal Repair

Principles of Regenerative Medicine

Volumn , Issue , 2008, Pages 888-911

  Li, Wan Ju ^a   Gollapudi, Kiran ^d   Patterson, David P ^a   Huang, George T J ^b   Tuan, Rocky S ^c  

^a National Institute of Arthritis Musculoskeletal and Skin Diseases   (United States)

^b UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 72049116487     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012369410-2.50053-X     Document Type: Chapter

References (92)

1. Abukawa H., Kaban L.B., Williams W.B., Terada S., Vacanti J.P., Troulis M.J. Effect of interferon-alpha-2b on porcine mesenchymal stem cells. J. Oral Maxillofac. Surg. 2006, 64:1214-1220.
2. Alhadlaq A., Mao J.J. Tissue-engineered neogenesis of human-shaped mandibular condyle from rat mesenchymal stemcells. J. Dent. Res. 2003, 82:951-956.
3. Awad H.A., Boivin G.P., Dressler M.R., Smith F.N., Young R.G., Butler D.L. Repair of patellar tendon injuries using a cell-collagen composite. J. Orthop. Res. 2003, 21:420-431.
4. Bach A.D., Beier J.P., Stern-Staeter J., Horch R.E. Skeletal muscle tissue engineering. J. Cell.Mol. Med.. 2004, 8:413-422.
5. Ball S.G., Shuttleworth A.C., Kielty C.M. Direct cell contact influences bone marrow mesenchymal stem cell fate. Int. J. Biochem. Cell Biol. 2004, 36:714-727.
6. Barry F., Boynton R.E., Liu B., Murphy J.M. Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation-dependent gene expression of matrix components. Exp. Cell Res. 2001, 268:189-200.
7. Bi W., Huang W., Whitworth D.J., Deng J.M., Zhang Z., Behringer R.R., de Crombrugghe B. Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization. Proc. Natl Acad. Sci. USA 2001, 98:6698-6703.
8. Boland G.M., Perkins G., Hall D.J., Tuan R.S. Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells. J. Cell. Biochem. 2004, 93:1210-1230.
9. Borschel G.H., Dennis R.G., Kuzon W.M. Contractile skeletal muscle tissue-engineered on a cellular scaffold. Plast. Reconstr. Surg. 2004, 113:595-602. discussion 603-604.
10. Brittberg M., Lindahl A., Nilsson A., Ohlsson C., Isaksson O., Peterson L. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N. Engl. J. Med. 1994, 331:889-895.
11. Caplan A.I. Mesenchymal stem cells. J. Orthop. Res. 1991, 9:641-650.
12. CDC Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation - United States, 2003-2005. MMWR Morb.Mortal. Wkly Rep. 2006, 55:1089-1092.
13. Chamberlain J.R., Schwarze U., Wang P.R., Hirata R.K., Hankenson K.D., Pace J.M., Underwood R.A., Song K.M., Sussman M., Byers P.H. Gene targeting in stem cells from individuals with osteogenesis imperfecta. Science 2004, 303:1198-1201.
14. Chang S.C., Chuang H.L., Chen Y.R., Chen J.K., Chung H.Y., Lu Y.L., Lin H.Y., Tai C.L., Lou J. Ex vivo gene therapy in autologous bone marrow stromal stem cells for tissue-engineered maxillofacial bone regeneration. Gene Ther. 2003, 10:2013-2019.
15. Chen F., Hui J.H., Chan W.K., Lee E.H. Cultured mesenchymal stem cell transfers in the treatment of partial growth arrest. J. Pediatr. Orthop. 2003, 23:425-429.
16. Chen F.H., Rousche K.T., Tuan R.S. Technology insight: adult stem cells in cartilage regeneration and tissue engineering. Nat. Clin. Pract. Rheumatol. 2006, 2:373-382.
17. Chen X.I., Armstrong M.A., Li G. Mesenchymal stem cells in immunoregulation. Immunol. Cell Biol. 2006, 84:413-421.
18. Chiang H., Kuo T.F., Tsai C.C., Lin M.C., She B.R., Huang Y.Y., Lee H.S., Shieh C.S., Chen M.H., Ramshaw J.A. Repair of porcine articular cartilage defect with autologous chondrocyte transplantation. J. Orthop.Res. 2005, 23:584-593.
19. Colter D.C., Class R., DiGirolamo C.M., Prockop D.J. Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow. Proc. Natl Acad. Sci. USA 2000, 97:3213-3218.
20. Deans R.J., Moseley A.B. Mesenchymal stem cells: biology and potential clinical uses. Exp. Hematol. 2000, 28:875-884.
21. Dezawa M., Ishikawa H., Itokazu Y, Yoshihara T., Hoshino M., Takeda S., Ide C., Nabeshima Y. Bone marrow stromal cells generate muscle cells and repair muscle degeneration. Science 2005, 309:314-317.
22. Dominici M., Le Blanc K., Mueller I., Slaper-Cortenbach I., Marini F., Krause D., Deans R., Keating A., Prockop D., Horwitz E. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006, 8:315-317.
23. Dreyfus P.A., Chretien F., Chazaud B., Kirova Y., Caramelle P., Garcia L., Butler-Browne G., Gherardi R.K. Adult bone marrow-derived stem cells in muscle connective tissue and satellite cell niches. Am. J. Pathol. 2004, 164:773-779.
24. Eames B.F., de la Fuente L., Helms J.A. Molecular ontogeny of the skeleton. Birth Defects Res. C Embryo Today 2003, 69:93-101.
25. Elisseeff J., Ferran A., Hwang S., Varghese S., Zhang Z. The role of biomaterials in stem cell differentiation: applications in the musculoskeletal system. Stem Cells Dev. 2006, 15:295-303.
26. Engler A.J., Sen S., Sweeney H.L., Discher D.E. Matrix elasticity directs stem cell lineage specification. Cell 2006, 126:677-689.
27. Fukuchi Y., Nakajima H., Sugiyama D., Hirose I., Kitamura T., Tsuji K. Human placenta-derived cells have mesenchymal stem/progenitor cell potential. Stem Cells 2004, 22:649-658.
28. Gersbach C.A., Le Doux J.M., Guldberg R.E., Garcia A.J. Inducible regulation of Runx2-stimulated osteogenesis. Gene Ther. 2006, 13:873-882.
29. Gregory C.A., Singh H., Perry A.S., Prockop D.J. The Wnt signaling inhibitor dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow. J. Biol. Chem. 2003, 278:28067-28078.
30. Haleem-Smith H., Derfoul A., Okafor C., Tuli R., Olsen D, Hall D.J., Tuan R.S. Optimization of high-efficiency transfection of adult human mesenchymal stem cells in vitro. Mol. Biotechnol. 2005, 30:9-20.
31. Hasegawa N., Kawaguchi H., Hirachi A., Takeda K., Mizuno N., Nishimura M., Koike C., Tsuji K., Iba H., Kato Y. Behavior of transplanted bone marrow-derived mesenchymal stem cells in periodontal defects. J. Periodontol. 2006, 77:1003-1007.
32. Hernigou P., Poignard A., Beaujean F., Rouard H. Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells. J. Bone Joint Surg. Am. 2005, 87:1430-1437.
33. Hibi H., Yamada Y., Ueda M., Endo Y. Alveolar cleft osteoplasty using tissue-engineered osteogenic material. Int. J. Oral Maxillofac. Surg. 2006, 35:551-555.
34. In't Anker P.S., Scherjon S.A., Kleijburg-van der Keur C., Noort W.A., Claas F.H., illemze R., Fibbe W.E., Kanhai H.H. Amniotic fluid as a novel source of mesenchymal stem cells for therapeutic transplantation. Blood 2003, 102:1548-1549.
35. Izuta Y., Ochi M., Adachi N., Deie M., Yamasaki T., Shinomiya R. Meniscal repair using bone marrowderived mesenchymal stem cells: experimental study using green fluorescent protein transgenic rats. Knee 2005, 12:217-223.
36. Jorgensen C., Djouad F., Fritz V., Apparailly F., Plence P., Noel D. Mesenchymal stem cells and rheumatoid arthritis. Joint Bone Spine 2003, 70:483-485.
37. Karp J.M., Ferreira L.S., Khademhosseini A., Kwon A.H., Yeh J., Langer R.S. Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis. in vitro Stem Cells 2006, 24:835-843.
38. Kern S., Eichler H., Stoeve J., Kluter H., Bieback K. Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 2006, 24:1294-1301.
39. Kim H., Lee J.H., Suh H. Interaction of mesenchymal stem cells and osteoblasts for in vitro osteoblasts. Yonsei Med. J. 2003, 44:187-197.
40. Kneser U., Stangenberg L., Ohnolz J., Buettner O., Stern-Straeter J., Mobest D., Horch R.E., Stark G.B., Schaefer D.J. Evaluation of processed bovine cancellous bone matrix seeded with syngenic osteoblasts in a critical size calvarial defect rat model. J. Cell. Mol. Med. 2006, 10:695-707.
41. Kramer J., Hegert C., Guan K., Wobus A.M., Muller P.K., Rohwedel J. Embryonic stem cell-derived chondrogenic differentiation in vitro:activation by BMP-2 and BMP-4. Mech. Dev. 2000, 92:193-205.
42. Kuo C.K., Li W.J., Mauck R.L., Tuan R.S. Cartilage tissue engineering: its potential and uses. Curr. Opin. Rheumatol. 2006, 18:64-73.
43. Lee R.H., Kim B., Choi I., Kim H., Choi H.S., Suh K., Bae Y.C., Jung J.S. Characterization and expression analysis of mesenchymal stem cells from human bone marrow and adipose tissue. Cell. Physiol. Biochem. 2004, 14:311-324.
44. Lefebvre V., Smits P. Transcriptional control of chondrocyte fate and differentiation. Birth Defects Res. C Embryo Today 2005, 75:200-212.
45. Levenberg S., Huang N.F., Lavik E., Rogers A.B., Itskovitz-Eldor J., Langer R. Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. Proc. Natl Acad. Sci. USA 2003, 100:12741-12746.
46. Li W.J., Tuli R., Huang X., Laquerriere P., Tuan R.S. Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold. Biomaterials 2005, 26:5158-5166.
47. Li W.J., Tuli R., Okafor C., Derfoul A., Danielson K.G., Hall D.J., Tuan R.S. A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells. Biomaterials 2005, 26:599-609.
48. Li W.J., Jiang Y.J., Tuan R.S. Chondrocyte phenotype in engineered fibrous matrix is regulated by fiber size. Tissue Eng. 2006, 12:1775-1785.
49. Li W.J., Mauck R.L., Cooper J.A., Yuan X., Tuan R.S. Engineering controllable anisotropy in electrospun biodegradable nanofibrous scaffolds for musculoskeletal tissue engineering. J. Biomech. 2007, 40:1686-1693.
50. Lieberman J.R., Daluiski A., Stevenson S., Wu L., McAllister P., Lee Y.P., Kabo J.M., Finerman G.A., Berk A.J., Witte O.N. The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats. J. Bone Joint Surg. Am. 1999, 81:905-917.
51. Lim J.K., Hui J., Li L., Thambyah A., Goh J., Lee E.H. Enhancement of tendon graft osteointegration using mesenchymal stem cells in a rabbit model of anterior cruciate ligament reconstruction. Arthroscopy 2004, 20:899-910.
52. Liu C.-H., Hwang S.-M. Cytokine interactions in mesenchymal stem cells from cord blood. Cytokine 2005, 32:270-279.
53. Liu W., Chen B., Deng D., Xu F., Cui L., Cao Y. Repair of tendon defect with dermal fibroblast engineered tendon in a porcine model. Tissue Eng. 2006, 12:775-788.
54. Lou J., Tu Y., Ludwig F.J., Zhang J., Manske P.R. Effect of bone morphogenetic protein-12 gene transfer on mesenchymal progenitor cells. Clin. Orthop. Relat. Res. 1999, 333-339.
55. Lu F.-Z., Fujino M., Kitazawa Y., Uyama T., Hara Y., Funeshima N., Jiang J.-Y., Umezawa A., Li X.-K. Characterization and gene transfer in mesenchymal stem cells derived from human umbilical-cord blood. J. Lab. Clin. Med. 2005, 146:271-278.
56. Madry H., Kaul G., Cucchiarini M., Stein U., Zurakowski D., Remberger K., Menger M.D., Kohn D., Trippel S.B. Enhanced repair of articular cartilage defects in vivo transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I). Gene Ther. 2005, 12:1171-1179.
57. Mareschi K., Biasin E., Piacibello W., Aglietta M., Madon E., Fagioli F. Isolation of human mesenchymal stem cells bone marrow versus umbilical cord blood. Haematologica 2001, 86:1099-1100.
58. Matsubara T., Tsutsumi S., Pan H., Hiraoka H., Oda R., Nishimura M., Kawaguchi H., Nakamura K., Kato Y. A new technique to expand human mesenchymal stem cells using basement membrane extracellular matrix. Biochem. Biophys. Res. Commun. 2004, 313:503-508.
59. Mauck R.L., Soltz M.A., Wang C.C., Wong D.D., Chao P.H., Valhmu W.B., Hung C.T., Ateshian G.A. Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J. Biomech. Eng. 2000, 122:252-260.
60. Mauney J.R., Blumberg J., Pirun M., Volloch V., Vunjak-Novakovic G., Kaplan D.L. Osteogenic differentiation of human bone marrow stromal cells on partially demineralized bone scaffolds in vitro. Tissue Eng. 2004, 10:81-92.
61. McBeath R., Pirone D.M., Nelson C.M., Bhadriraju K., Chen C.S. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev. Cell 2004, 6:483-495.
62. Meisel H.J., Ganey T., Hutton W.C., Libera J., Minkus Y., Alasevic O. Clinical experience in cell-based therapeutics: intervention and outcome. Eur. Spine J. 2006, 15(Suppl 15):397-405.
63. Miyanishi K., Trindade M.C., Lindsey D.P., Beaupre G.S., Carter D.R., Goodman S.B., Schurman D.J., Smith R.L. Dose- and time-dependent effects of cyclic hydrostatic pressure on transforming growth factor-beta3-induced chondrogenesis by adult human mesenchymal stem cel. Tissue Eng. 2006, 12:2253-2262.
64. Nussenbaum B., Krebsbach P.H. The role of gene therapy for craniofacial and dental tissue engineering. Adv. Drug Deliv. Rev. 2006, 58:577-591.
65. Ohazama A., Modino S.A., Miletich I., Sharpe P.T. Stem-cell-based tissue engineering of murine teeth. J. Dent. Res. 2004, 83:518-522.
66. Okafor C.C., Haleem-Smith H., Laqueriere P., Manner P.A., Tuan R.S. Particulate endocytosis mediates biological responses of human mesenchymal stem cells to titanium wear debris. J. Orthop. Res. 2006, 24:461-473.
67. Park Y., Lutolf M.P., Hubbell J.A., Hunziker E.B., Wong M. Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair. Tissue Eng. 2004, 10:515-522.
68. Paul R., Haydon R.C., Cheng H., Ishikawa A., Nenadovich N., Jiang W., Zhou L., Breyer B., Feng T., Gupta P. Potential use of Sox9 gene therapy for intervertebral degenerative disc disease. Spine 2003, 28:755-763.
69. Pittenger M.F., Mackay A.M., Beck S.C., Jaiswal R.K., Douglas R., Mosca J.D., Moorman M.A., Simonetti D.W., Craig S., Marshak D.R. Multilineage potential of adult human mesenchymal stem cells. Science 1999, 284:143-147.
70. Qi M., Hu J., Zou S., Zhou H., Han L. Mandibular distraction osteogenesis enhanced by bone marrow mesenchymal stem cells in rats. J. Craniomaxillofac. Surg. 2006, 34:283-289.
71. Quarto R., Mastrogiacomo M., Cancedda R., Kutepov S.M., Mukhachev V., Lavroukov A., Kon E., Marcacci M. Repair of large bone defects with the use of autologous bone marrow stromal cells. N. Engl. J. Med.. 2001, 344:385-386.
72. Romanov Y.A., Svintsitskaya V.A., Smirnov V.N. Searching for alternative sources of postnatal human mesenchymal stem cells: candidate MSC-like cells from umbilical cord. Stem Cells 2003, 21:105-110.
73. Rotter N., Ung F., Roy A.K., Vacanti M., Eavey R.D., Vacanti C.A., Bonassar L.J. Role for interleukin 1alpha in the inhibition of chondrogenesis in autologous implants using polyglycolic acid-polylactic acid scaffolds. Tissue Eng. 2005, 11:192-200.
74. Rouwkema J., de Boer J., Van Blitterswijk C.A. Endothelial cells assemble into a 3-dimensional prevascular network in a bone tissue engineering construct. Tissue Eng. 2006, 12:2685-2693.
75. Sampaolesi M., Blot S., D'Antona G., Granger N., Tonlorenzi R., Innocenzi A., Mognol P., Thibaud J.L., Galvez B.G., Barthelemy I. Mesangioblast stem cells ameliorate muscle function in dystrophic dogs. Nature 2006, 444:574-579.
76. Sartorelli V., Caretti G. Mechanisms underlying the transcriptional regulation of skeletal myogenesis. Curr. Opin. Genet. Dev. 2005, 15:528-535.
77. Schofield R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 1978, 4:7-25.
78. Sekiya I., Larson B.L., Vuoristo J.T., Reger R.L., Prockop D.J. Comparison of effect of BMP-2, -4, and -6 on in vitro formation of human adult stem cells from bone marrow stroma. Cell Tissue Res. 2005, 320:269-276.
79. Shen F.H., Visger J.M., Balian G., Hurwitz S.R., Diduch D.R. Systemically administered mesenchymal stromal cells transduced with insulin-like growth factor-I localize to a fracture site and potentiate healing. J. Orthop. Trauma. 2002, 16:651-659.
80. Steck E., Bertram H., Abel R., Chen B., Winter A., Richter W. Induction of intervertebral disc-like cells from adult mesenchymal stem cells. Stem Cells 2005, 23:403-411.
81. Tamaki T., Akatsuka A., Ando K., Nakamura Y., Matsuzawa H., Hotta T., Roy R.R., Edgerton V.R. Identification of myogenic-endothelial progenitor cells in the interstitial spaces of skeletal muscle. J. Cell Biol. 2002, 157:571-577.
82. Tozer S., Duprez D. Tendon and ligament: development, repair and disease. Birth Defects Res. C Embryo Today 2005, 75:226-236.
83. Tuan R.S., Boland G., Tuli R. Adult mesenchymal stem cells and cell-based tissue engineering. Arthr. Res. Ther. 2003, 5:32-45.
84. Tuli R., Tuli S., Nandi S., Huang X., Manner P.A., Hozack W.J., Danielson K.G., Hall D.J., Tuan R.S. Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt. J. Biol. Chem. 2003, 278:41227-41236.
85. Tuli R., Nandi S., Li W.J., Tuli S., Huang X., Manner P.A., Laquerriere P., Noth U., Hall D.J., Tuan R.S. Human mesenchymal progenitor cell-based tissue engineering of a single-unit osteochondral construct. Tissue Eng. 2004, 10:1169-1179.
86. Vacanti C.A., Bonassar L.J., Vacanti M.P., Shufflebarger J. Replacement of an avulsed phalanx with tissueengineered bone. N. Engl. J. Med. 2001, 344:1511-1514.
87. Veilleux N., Spector M. Effects of FGF-2 and IGF-1 on adult canine articular chondrocytes in type II collagen- glycosaminoglycan scaffolds in vitro. Osteoarthr. Cartilage 2005, 13:278-286.
88. Wakitani S., Imoto K., Yamamoto T., Saito M., Murata N., Yoneda M. Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees. Osteoarthr. Cartilage 2002, 10:199-206.
89. Wakitani S., Aoki H., Harada Y., Sonobe M., Morita Y., Mu Y., Tomita N., Nakamura Y., Takeda S., Watanabe T.K. Embryonic stem cells form articular cartilage, not teratomas, in osteochondral defects of rat joints. Cell Transplant. 2004, 13:331-336.
90. Yamada Y., Ueda M., Naiki T., Nagasaka T. Tissue-engineered injectable bone regeneration for osteointegrated dental implants. Clin. Oral Implants Res. 2004, 15:589-597.
91. Yamada Y., Ueda M., Hibi H., Baba S. A novel approach to periodontal tissue regeneration with mesenchymal stem cells and platelet-rich plasma using tissue engineering technology: a clinical case. Int. J. Periodont. Rest. Dent. 2006, 26:363-369.
92. Young B.H., Peng H., Huard J. Muscle-based gene therapy and tissue engineering to improve bone healing. Clin. Orthop. Relat. Res. 2002, S243-S251.