Synthesis, spectral characterization and biological evaluation of phosphorylated derivatives of galanthamine

European Journal of Medicinal Chemistry

Volumn 45, Issue 1, 2010, Pages 203-209

  Koteswara Rao, V ^a   Janardhan Rao, A ^a   Subba Reddy, S ^a   Naga Raju, C ^a   Visweswara Rao, P ^a   Ghosh, S K ^b  

^a SRI VENKATESWARA UNIVERSITY   (India)

^b BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Antimicrobial activity; Antioxidant activity; Gram negative bacteria; Gram positive bacteria; Phosphorylated derivatives of galanthamine

Indexed keywords

2 AMINO ETHYLMERCAPTO(3 AMINO 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)(4 NITROPHENYL)PHOSPHATE; 2 AMINO ETHYLMERCAPTO(3 AMINO 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)BIS(2 CHLOROETHYL)AMINO PHOSPHATE; 2 AMINOETHYLAMINO(3 METHOXY 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)(4 NITROPHENYL)PHOSPHATE; 2 AMINOETHYLAMINO(3 METHOXY 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)BIS(2 CHLOROETHYL)AMINO PHOSPHATE; 2 DIHYDROGENPHOSPHATO(3 METHOXY 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)(4 NITROPHENYL)PHOSPHATE; 2 DIHYDROGENPHOSPHATO(3 METHOXY 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)BIS(2 CHLOROETHYL)AMINO PHOSPHATE; 2 HYDROXY ETHYLAMINO(3 METHOXY 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)(4 NITROPHENYL)PHOSPHATE; 2 HYDROXY ETHYLAMINO(3 METHOXY 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)BIS(2 CHLOROETHYL)AMINO PHOSPHATE; 2 HYDROXY ETHYLMERCAPTO(3 METHOXY 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)(4 NITROPHENYL)PHOSPHATE; 2 HYDROXY ETHYLMERCAPTO(3 METHOXY 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)BIS(2 CHLOROETHYL)AMINO PHOSPHATE; 2 HYDROXYETHOXY(3 METHOXY 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)(4 NITROPHENYL)PHOSPHATE; 2 HYDROXYETHOXY(3 METHOXY 11 METHYL 5,6,9,10,11,12 HEXAHYDRO 4AH 4 OXA 11 AZACYCLOHEPTA[DE]FLUOREN 6 YL)BIS(2 CHLOROETHYL)AMINO PHOSPHATE; ETHANOLAMINE; ETHYLENE GLYCOL; ETHYLENEDIAMINE; GALANTAMINE; MERCAPTAMINE; MERCAPTOETHANOL; TETRAHYDROFURAN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; NONHUMAN; PHOSPHORYLATION; RAT;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIOXIDANTS; BACTERIA; CATALASE; GALANTAMINE; GLUTATHIONE; LIPID PEROXIDATION; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; PHOSPHORYLATION; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 72049112827     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.09.045     Document Type: Article

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