Syntheses and evaluation of the antioxidant activity of acitretin analogs with amide bond(s) in the polyene spacer

European Journal of Medicinal Chemistry

Volumn 45, Issue 1, 2010, Pages 298-310

  Hadjipavlou Litina, Dimitra ^a   Magoulas, George E ^b   Krokidis, Marios ^b   Papaioannou, Dionissios ^b  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b School of Health Sciences   (Greece)

Author keywords

Acitretin analog; Anti inflammatory activity; Antioxidant activity; Lipid peroxidation; Lipoxygenase inhibitor; Retinoid

Indexed keywords

3 [1 [(3 BENZO[D][1,3]DIOXOL 5 YL)ACRYLOYL] 1H INDOL 3 YL]ACRYLIC ACID; 3 [3 OXO 1 (2,4,5 TRIMETHOXYPHENYL) 2,3 DIHYDRO 1H PYRROLO[1,2 A]INDOL 9 YL]ACRYLIC ACID; 4 [3 (2,4 DIMETHOXYPHENYLCARBAMOYL) 1H INDOL 1 YL] 4 OXOBUT 2 ENOIC ACID; 4 [3 (3 NITROPHENYLCARBAMOYL) 1H INDOL 1 YL] 4 OXOBUT 2 ENOIC ACID; 4 OXO 4 [3 (PHENYLCARBAMOYL) 1H INDOL 1 YL] BUT 2 ENOIC ACID; ALDEHYDE DERIVATIVE; ANTIOXIDANT; CARBOXYLIC ACID DERIVATIVE; ETRETIN; FLUORENONE DERIVATIVE; LIPOXYGENASE; PYRROLE DERIVATIVE; TERT BUTYL 3 [1 [(3 (2,4,5 TRIMETHOXYPHENYL)ACRYLOYL] 1H INDOL 3 YL]ACRYLATE; TERT BUTYL 3 [1 [(3 BENZO[D][1,3]DIOXOL 5 YL)ACRYLOYL] 1H INDOL 3 YL]ACRYLATE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS;

ACITRETIN; AMIDES; ANIMALS; ANTIOXIDANTS; EDEMA; ELECTRONS; ESTERS; FEMALE; HETEROCYCLIC COMPOUNDS; HYDROPHOBICITY; INFLAMMATION; LIPID PEROXIDATION; LIPOXYGENASE; LIPOXYGENASE INHIBITORS; MALE; POLYENES; RATS; SOYBEANS;

EID: 72049101878     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.10.012     Document Type: Article

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